Plants with toxic alkaloids - University of Washington

Plants with toxic alkaloids - University of Washington Plants with toxic alkaloids - University of Washington

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Teratogenic Plants Teratogens cause abnormalities of physiological development; which in mammals early appear as birth defects . Approx. 1 % of all livestock in US rangeland shows birth defects from teratogenic plants. Western False Hellebore = Corn lily = Veratrum californicum causes poisoning in sheep, cattle and goat. Identified teratogens are the steroidal alkaloids cyclopamine, cycloposine and jervine interfering with neurological embryo development causing lambs with monkeyfaces and one eye (cyclopsis) Lupines Lupinus ssp Conium and Nicotiana contain piperidine & quinolizidine alkaloids inducing birth defects in the form of palate cleft (lips). Quinolizidine alkaloid anagyrine causes birth defects in cattle. Other piperidine alkaloids affect birth defects in in sheep and goats. Coniine & anabasine (from Nicotiana) cause similar effects in swine, gaots, sheep and cattle.

Rhubarb RheumXcultorum malic acid in petiole, oxalic acid + anthraquinone glycos. In blades intern bleeding lethal Corn lily Veratrum viride/ protoanemonin – typical highly toxic alkaloids malformations, cramps Pokeweed Phytolacca amer stomach pain, cramps, convulsions espec. From root

Rhubarb RheumXcultorum<br />

malic acid in petiole, oxalic<br />

acid + anthraquinone glycos.<br />

In blades intern bleeding<br />

lethal<br />

Corn lily Veratrum viride/<br />

protoanemonin – typical<br />

highly <strong>toxic</strong> <strong>alkaloids</strong> <br />

malformations, cramps<br />

Pokeweed Phytolacca amer<br />

stomach pain, cramps,<br />

convulsions espec. From<br />

root

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