Plants with toxic alkaloids - University of Washington

Plants with toxic alkaloids - University of Washington Plants with toxic alkaloids - University of Washington

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Speckled Locoweed Astralagus lentiginosous Neurotoxins cause crazy behavior = locoism, lifestock may seek locoweeds instead of healthy food plants nerve cells damaged , bad death Poison vetch Astralagus pectinatus Accumulates selenium “blind staggers” in lifestock …death

Teratogens Teratology is the study of abnormalities of physiological development. Narrowly thought of as the study of birth defects, it is much broader than that, taking in other developmental stages, such as puberty; and other life forms, such as plants. The term was popularized in the 1960s by Dr. David W. Smith of the University of Washington Medical School, who became known in 1973 for the discovery of Fetal alcohol syndrome. Drugs and medications: tobacco, caffeine, drinking alcohol (ethanol), isotretinoin (13cis-retinoic acid, Roaccutane) = a anti ACNE medication, temazepam (Restoril; Normisson), nitrazepam (Mogadon), nimetazepam (Ermin), aminopterin, coumarin, diethylstilbestrol, phenytoin Environmental chemicals: polychlorinated biphenyls (PCBs), polychlorinated dibenzodioxins a.k.a dioxin, polychlorinated dibenzofurans (PCDFs), , organic mercury, ethidium bromide, etc. Ionizing radiation: atomic fallout, diagnostic x-rays, radiation Infections: cytomegalovirus, herpes virus, parvovirus B19, rubella virus (German measles), syphilis, toxoplasmosis, encephalitis virus. Metabolic imbalance: alcoholism, diabetes, folic acid deficiency, iodine deficiency,hyperthermia, phenylketonuria, rheumatism

Speckled Locoweed<br />

Astralagus lentiginosous<br />

Neurotoxins cause<br />

crazy behavior = locoism,<br />

lifestock may seek locoweeds<br />

instead <strong>of</strong> healthy food plants<br />

nerve cells damaged ,<br />

bad death<br />

Poison vetch<br />

Astralagus pectinatus<br />

Accumulates selenium<br />

“blind staggers” in lifestock<br />

…death

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