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Plants with toxic alkaloids - University of Washington

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Papaveracea – Poppy family -Opium<br />

Opium lachryma papaveris) is the dried<br />

latex from the opium poppy Papaver<br />

somniferum containing up to 12%<br />

morphine, adjusted for medicine to 10 %<br />

(Europe).<br />

Morphine is a potent opiate analgesic<br />

medication. It was the first alkaloid to be<br />

isolated in 1804 by Friedrich Sertürner,<br />

a “Apotheker” in Halle (Germany), first<br />

distributed by same in 1817, and first<br />

commercially sold by Merck in 1827,<br />

which at the time was a single small<br />

chemists' shop in Darmstadt.<br />

Morphine is regarded as the gold standard <strong>of</strong> analgesics to relieve severe, agonizing<br />

pain. Like other opioids, such as oxycodone, hydromorphone, and diacetylmorphine<br />

(heroin), it acts directly on the CNS. Morphine has a high potential for addiction;<br />

tolerance and psychological dependence develop rapidly,

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