Health Assessment Document for Diesel Emissions - NSCEP | US ...
Health Assessment Document for Diesel Emissions - NSCEP | US ...
Health Assessment Document for Diesel Emissions - NSCEP | US ...
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
N -,_.<br />
-\0<br />
00<br />
VI<br />
N<br />
,_.<br />
0<br />
§ I<br />
I<br />
0<br />
0<br />
z<br />
0<br />
...,<br />
- (')<br />
...,<br />
tr1<br />
0<br />
:::0<br />
10<br />
c:::<br />
0<br />
...,<br />
tr1<br />
Species/sex<br />
Mouse!CR,M<br />
Rat, Sprague<br />
Dawley,<br />
M<br />
'Irradiated exhaust.<br />
PMN =Polymorphonuclear leukocyte.<br />
AM =Alveolar macrophage.<br />
Table 5-2. Short-term effects of diesel exhaust on laboratory animals (continuted)<br />
Exposure<br />
period<br />
6 weeks<br />
24 h<br />
Particles<br />
(mg/m 3 )<br />
100 J.lgDPM<br />
intranasally<br />
5-100 J.lg/10 6<br />
AM/mlofDPM<br />
CxT<br />
(mg·h/m 3 )<br />
co<br />
(ppm)<br />
N0 1<br />
(ppm)'<br />
so 1<br />
(ppm) Effects Study<br />
DPM aggravated ovalbumin- Takano et at. (1997)<br />
induced airway inflammation and<br />
provided evidence that DPM can<br />
enhance manifestations of<br />
allergic asthma<br />
Unchanged, but not organic-free Yang et at. (1997)<br />
DPM enhanced production of<br />
proinflammatory cytokines
Change language