25.03.2013 Views

Quantitative Sensory Testing (QST) - Does assessing ... - TI Pharma

Quantitative Sensory Testing (QST) - Does assessing ... - TI Pharma

Quantitative Sensory Testing (QST) - Does assessing ... - TI Pharma

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

Contents<br />

Chapter 1<br />

1. General introduction<br />

1.1. Neuropathic pain<br />

1.1.1. Diagnosis of neuropathic pain<br />

1.1.2. Treatment of neuropathic pain<br />

1.2. <strong>Quantitative</strong> <strong>Sensory</strong> <strong>Testing</strong> (<strong>QST</strong>)<br />

1.2.1. <strong>QST</strong> and homogenous groups of somatosensory abnormalities<br />

Chapter 2<br />

Bilateral sensory abnormalities in patients with unilateral neuropathic<br />

pain; a <strong>Quantitative</strong> <strong>Sensory</strong> <strong>Testing</strong> (<strong>QST</strong>) study<br />

Abstract<br />

1. Introduction<br />

2. Methods<br />

2.1. Description of healthy controls<br />

2.2. Description of the patient cohort<br />

2.3. <strong>Quantitative</strong> sensory testing (<strong>QST</strong>)<br />

2.4. Data analysis and statistics<br />

2.4.1. Z-transformation of <strong>QST</strong> data<br />

2.4.2 Proportion of patients with sensory abnormalities at the affected side<br />

2.4.3. Proportion of patients with sensory abnormalities at the contralateral side<br />

2.4.4. Proportion of patients with sensory abnormalities for the same<br />

<strong>QST</strong> parameter at the affected and contralateral side<br />

2.4.5. Correlation between background pain and sensory abnormalities<br />

2.4.6. Correlation between numbers of sensory abnormalities at the affected<br />

and contralateral side<br />

3. Results<br />

3.1. <strong>QST</strong> observations in healthy controls<br />

3.1.1. <strong>Sensory</strong> function in healthy controls<br />

3.2. Demographics of patients<br />

3.3. <strong>QST</strong> observations in patients<br />

3.3.1. <strong>Sensory</strong> function in patients<br />

3.3.2. <strong>Sensory</strong> changes at patients affected side<br />

3.3.3. <strong>Sensory</strong> changes at the patient’s contralateral side<br />

3.3.3.1. Example of magnitude of somatosensory abnormalities<br />

13<br />

15<br />

17<br />

19<br />

19<br />

21<br />

22<br />

25<br />

26<br />

27<br />

28<br />

28<br />

28<br />

29<br />

29<br />

29<br />

30<br />

30<br />

30<br />

31<br />

31<br />

31<br />

31<br />

31<br />

32<br />

34<br />

34<br />

36<br />

38<br />

39

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!