Quantitative Sensory Testing (QST) - Does assessing ... - TI Pharma

2. Bilateral abnormalities in neuropathic pain
findings reporting 41% abnormalities using the QST protocol (Maier et al 2010).
In our healthy volunteers, abnormalities were observed across all QST parameters with
the exception of DMA. The detected sensory abnormalities reflected gain of function
for the most part, some loss of function and in a minority fraction both gain and loss of
function (Fig 2-1).
Although previously reported otherwise (Maier et al 2010), in the present study, PHS
>1 occurred in 1.4% at the test side “dorsal hand” and in 9.3% at the test side “dorsal
foot”. The presence of abnormal PHS in our study could be associated with a greater
likelihood of sensory dysfunction with an increase in age (r=0.193; p