Quantitative Sensory Testing (QST) - Does assessing ... - TI Pharma

2. Bilateral abnormalities in neuropathic pain
Thermal hypesthesias were observed also in most of the patients for CDT, WDT and
TSL. For MDT there was predominantly a sensory loss observed indicating a mechanical
hypesthesia. It was possible to detect hyperesthesia for VDT for one patient, but for the
large majority VDT responses indicated hypesthesia.
In 25% (n=20) of the patients a sensory gain for PHS was detected at the affected side.
DMA was present in 26% of the patients, in 6% of very mild intensity, however, 20%
of patients showed a clinical relevant increased response for DMA indicating a dynamic
allodynia.
3.3.3. Sensory changes at the patient’s contralateral side
Sensory abnormalities at the contralateral side ranged from 1.2% (n=1) for CPT to
29.6% (n=24) for PPT. With the exception of CPT, 95% Confidence Intervals confirmed
that the prevalence differed significantly from zero (p