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Normal Reference Range - Blood Test Results Decoded

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Contains The Complete <strong>Blood</strong> Count (CBC) and<br />

Differential


WBC Meaning & <strong>Range</strong>s<br />

White <strong>Blood</strong> Cell Count is the actual number<br />

of white blood cells per volume of blood<br />

White blood cells are cells that make up the<br />

immune system in the blood<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: 4.5 – 10 10 3 /μL<br />

Optimal <strong>Range</strong>: 5.5 – 10 10 3 /μL


Causes of High/Low WBC<br />

The upper end of normal means your immune<br />

system is definitely producing enough white<br />

blood cells to prevent infections<br />

High WBC levels means that there is an<br />

infection or leukemia (cancer of the blood)<br />

Low WBC levels could be due to an immune<br />

deficiency or a liver or spleen disorder


Treating High WBC<br />

Medications - Antibiotics, steroids,<br />

chemotherapy for cancer<br />

Procedures - Leukapheresis, bone marrow<br />

treatment for cancer<br />

Diet changes - Drink more water, less fat and<br />

sugar intake, increase fiber and eat garlic and<br />

omega-3 foods<br />

Supplements - Probiotics, echinacea, tea tree oil<br />

(topically) and other herbs


Treating Low WBC<br />

Medications - Meloid growth factors<br />

Diet changes - Eat carrots, spinach, kale, garlic<br />

Supplements - Oleander extract, selenium,<br />

ginseng, Siberian ginseng, Echinacea, green<br />

tea, pau d'arco, suma root, beta glucans, aloe<br />

vera, probiotics


RBC Meaning & <strong>Range</strong>s<br />

Red blood cell count is the actual number of<br />

red blood cells per volume of blood<br />

Red blood cells are the ones that carry oxygen<br />

and remove carbon dioxide<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: male 5 – 6 <br />

10 6 /μL and female 4 – 5 10 6 /μL<br />

Optimal <strong>Range</strong>: male 5 – 6 10 6 /μL and<br />

female 4 – 5 10 6 /μL


Hemoglobin Meaning & <strong>Range</strong>s<br />

Hemoglobin is the amount of oxygen-carrying<br />

protein in the blood’s red blood cells.<br />

It also carries toxic carbon dioxide from your<br />

tissues and organs back to your lungs<br />

This iron-containing protein makes blood red<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: male 14 – 17.5<br />

g/dL and female 12.3 – 15.3 g/dL<br />

Optimal <strong>Range</strong>: male 14 – 17.5 g/dL and<br />

female 12.3 – 15.3 g/dL


Hematocrit Meaning & <strong>Range</strong>s<br />

Hematocrit measures the percentage of red<br />

blood cells in a given volume of whole blood<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: male 40.7 –<br />

50.3% and female 36.1 – 44.3%<br />

Optimal <strong>Range</strong>: male 40.7 – 50.3% and<br />

female 36.1 – 44.3%<br />

The hematocrit not only depends on how many<br />

red blood cells there are, but also how big they<br />

are


Causes of High/Low <strong>Results</strong><br />

High results can indicate dehydration,<br />

congenital heart disease, kidney tumor,<br />

pulmonary fibrosis or can be the result of<br />

smoking cigarettes<br />

Low results can indicate anemia


Treating High <strong>Results</strong><br />

Medications - Aspirin or cancer drugs like<br />

Hydrea or Leukeran<br />

Procedures - Phlebotomy (bloodletting) for<br />

high RBC<br />

Diet changes - Drink more water<br />

Supplements - Stay away from iron<br />

Lifestyle Changes - Quit smoking


Treating Low <strong>Results</strong><br />

Medications - Procrit, Epogen, Aranesp<br />

Procedures - <strong>Blood</strong> transfusion, bone marrow<br />

transplant<br />

Diet changes - Eat red meat, liver, greens,<br />

beans<br />

Supplements - Iron, B12, B6, folic acid and<br />

many herbs


MCV Meaning & <strong>Range</strong>s<br />

Mean Corpuscular Volume (MCV) measures<br />

the average size of your red blood cells<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: 80 – 100 fL<br />

Optimal <strong>Range</strong>: 80 – 100 fL


MCH Meaning & <strong>Range</strong>s<br />

Mean corpuscular hemoglobin (MCH) is a<br />

calculation of the average amount of oxygencarrying<br />

hemoglobin inside a red blood cell<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: 27 – 31 pg<br />

Optimal <strong>Range</strong>: 27 – 31 pg


Causes of High/Low MCV/MCH<br />

High MCV/MCH can be a result of macrocytic<br />

anemia (likely due to vitamin deficiencies),<br />

liver disease, hypothyroidism, myelofibrosis,<br />

reticulocytosis<br />

Low MCV/MCH can be due to lead poisoning,<br />

microcytic anemia (likely due to iron<br />

deficiency), hemoglobinopathy (genetic<br />

disorder resulting in abnormally-shaped<br />

hemoglobin, unable to efficiently carry<br />

oxygen)


Treating High MCV/MCH<br />

Procedures - <strong>Blood</strong> transfusion<br />

Diet changes - Foods high in B12 and folic<br />

acid<br />

Supplements - B12


Treating Low MCV/MCH<br />

Medications - For lead poisoning, chelation<br />

therapy may be used or the drug EDTA.<br />

Extreme iron deficiency can be treated with<br />

hemodialysis or with an IV drip.<br />

Diet changes - Foods high in iron<br />

Supplements - Iron tablets


MCHC Meaning & <strong>Range</strong>s<br />

Mean corpuscular hemoglobin concentration<br />

(MCHC) is a calculation of the average<br />

concentration of hemoglobin inside a red cell<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: 32 – 36 g/dL<br />

Optimal <strong>Range</strong>: 32 – 36 g/dL


Causes of High/Low MCHC<br />

Low MCHC (hypochromia) is seen in<br />

conditions where the hemoglobin is abnormally<br />

diluted inside the red cells, such as in iron<br />

deficiency anemia and in thalassemia<br />

High MCHC (hyperchromia) is seen in<br />

conditions where the hemoglobin is abnormally<br />

concentrated inside the red cells, such as in<br />

burn victims


Treating High/LowMCHC<br />

Supplements - For high MCHC, vitamin B12<br />

Supplements - For low MCHC, iron tablets


RDW Meaning & <strong>Range</strong>s<br />

Red cell distribution width (RDW) is a<br />

calculation of the variation in the size of your<br />

red blood cells<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: 11 – 15%<br />

Optimal <strong>Range</strong>: 11 – 15%


Causes of High/Low RDW<br />

High RDW is due to pernicious anemia<br />

(anemia due to an inability to absorb vitamin<br />

B12 from foods and supplements)<br />

Low RDW indicates that your red blood cells<br />

are all very close in size (they could all be very<br />

large – macrocytic anemia – or all very small –<br />

microcytic anemia)


Treating High/Low RDW<br />

Medications - For low RDW, iron tablets or<br />

erythropoietin, epoetin and alfa, which<br />

stimulate red blood cell production and for<br />

high RDW, B12 shot<br />

Diet changes –For high RDW, B12 enriched<br />

foods and for low RDW, iron rich foods<br />

Supplements – For high RDW, B12 and for low<br />

RDW, B12 and iron


Platelets Meaning & <strong>Range</strong>s<br />

The platelet count is the number of platelets in<br />

a given volume of blood; these disc-shaped<br />

cells are your body's main clotting factor,<br />

which help form blood clots<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: 150 – 450 ×<br />

10 3 /μL<br />

Optimal <strong>Range</strong>: 240 – 400 × 10 3 /μL<br />

Both increases and decreases can point to<br />

conditions of excess bleeding or clotting


Causes of High/Low Platelets<br />

High platelets indicate thrombocytosis, mildly<br />

high platelets indicate chronic infection, very<br />

high platelets indicate myeloproliferative<br />

disorder (abnormal growth of blood cell<br />

elements in the bone marrow)<br />

Low platelets indicate thrombocytopenia,<br />

disseminated intravascular coagulation,<br />

hemolytic anemia, hypersplenism, idiopathic<br />

thrombocytopenic purpura or leukemia—<br />

mostly all due to a chronic infection<br />

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31<br />

Treating High/Low Platelets<br />

Medications - For high platelets, Anagrelide<br />

(Agrylin/Xagrid) is a platelet reducing agent and<br />

for low platelets, antibiotics for infection or<br />

drugs for specific diseases<br />

Diet changes - For low platelets, avoid red<br />

meat, dairy, alcohol<br />

Supplements - For high platelets, low dose<br />

Aspirin and for low platelets, vitamin K and fish<br />

oils


Neutrophils Meaning &<br />

<strong>Range</strong>s<br />

<strong>Normal</strong>ly the most abundant type of white<br />

blood cell in healthy adults; these are the white<br />

blood cells that are first in line to fight infection<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: 2.5 – 7 × 10 3 /μL<br />

Optimal <strong>Reference</strong> <strong>Range</strong>: 3 – 6.5 × 10 3 /μL


Causes of High/Low<br />

Neutrophils<br />

High neutrophils is called neutrophilia and is a<br />

result of a short-term bacterial infection<br />

Low neutrophils is called neutropenia and is<br />

usually caused by viral infections, radiotherapy<br />

and chemotherapy<br />

34


Treating High/Low Neutrophils<br />

35<br />

Medications - For high neutrophils, antibiotics<br />

and for low neutrophils, antibiotics or<br />

antifungals


Lymphocytes Meaning &<br />

<strong>Range</strong>s<br />

Lymphocytes normally make up about 25% of<br />

the total white blood cell count and have two<br />

kinds: B cells, which produce antibodies, and T<br />

cells, which recognize invaders and process<br />

them for removal<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: 1 – 4.8 × 10 3 /μL<br />

Optimal <strong>Range</strong>: 2.5 – 4.5 × 10 3 /μL


Causes of High/Low<br />

Lymphocytes<br />

38<br />

High lymphocytes can indicate the flu, chicken<br />

pox, tuberculosis, leukemia, mumps or rubella<br />

Low lymphocytes are usually a result of the<br />

body producing lymphocytes in an abnormal<br />

manner due to stress, malnutrition, Hodgkins<br />

disease or an immune disorder such as AIDS


Treating High/Low Lymphocytes<br />

Medications - For high lymphocytes,<br />

antibiotics or drugs specified for illness and<br />

for low lymphocytes, antibiotics<br />

Diet changes - For high lymphocytes, high<br />

protein and for low lymphocytes, foods rich in<br />

antioxidants, vitamins and minerals<br />

Supplements - For high lymphocytes,<br />

vitamin C and zinc and for low lymphocytes,<br />

vitamin supplements<br />

39<br />

39


Monocytes Meaning &<br />

<strong>Range</strong>s<br />

Monocytes ―eat‖ bacteria and other foreign<br />

particles to destroy them; they make up 5-10%<br />

of the total white blood cell count.<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: 0.2 – 0.6 ×<br />

10 3 /μL<br />

Optimal <strong>Range</strong>: 0.2 – 0.6 × 10 3 /μL


Causes of High/Low<br />

Monocytes<br />

High monocytes is called monocytosis and can<br />

be due to inflammation, stress, an autoimmune<br />

disease or sepsis<br />

Low monocytes is called monocytopenia,<br />

which is which is a form of leukopenia<br />

42


Treating High/Low Monocytes<br />

43<br />

Medications - For high monocytes, drugs to treat<br />

condition causing the high levels and for low<br />

monocytes, antibiotics.<br />

Diet changes - For high monocytes, food rich in<br />

antioxidants<br />

Supplements - For high monocytes, fish oils


Eosinophils Meaning &<br />

<strong>Range</strong>s<br />

Eosinophils are believed to function in allergic<br />

responses and in resisting some infections<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: 0.1 – 0.4 ×<br />

10 3 /μL<br />

Optimal <strong>Range</strong>: 0.1 – 0.3 × 10 3 /μL


Causes of High/Low<br />

Eosinophils<br />

High eosinophils indicate allergies, eczema,<br />

asthma or an autoimmune disease<br />

Low eosinophils is usually due to a bacterial<br />

infection or Cushing's disease<br />

46


Treating High/Low Eosinophils<br />

47<br />

Medications - For high eosinophils, allergy or<br />

asthma medications and for low eosinophils,<br />

corticosteroids or antibody therapy to fight the<br />

infection<br />

Diet changes - For high eosinophils, fruits,<br />

nuts and antioxidant-rich foods<br />

Supplements - For high eosinophils,<br />

quercetin to reduce allergies or asthma


Basophils Meaning & <strong>Range</strong>s<br />

Basophils are involved in the beginning stages<br />

of inflammation, which is the body's reaction to<br />

injury or irritation<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: 0.04 – 0.1 ×<br />

10 3 /μL<br />

Optimal <strong>Range</strong>: 0.04 – 0.1 × 10 3 /μL


Causes of High/Low<br />

Basophils<br />

High basophils indicate a parasitic infection<br />

Low basophils are hard to diagnose as basophil<br />

levels are normally at an extremely low level<br />

50


Treating High Basophils<br />

51<br />

Medications - Appropriate anti-parasitic<br />

Diet changes - Large amounts of water and<br />

fiber<br />

Supplements - Probiotics, garlic, vitamin C


Immature Granulocyte Meaning &<br />

<strong>Range</strong>s<br />

Immature granulocytes are white blood cells<br />

that will become monocytes, eosinophils and<br />

basophils<br />

<strong>Normal</strong> <strong>Reference</strong> <strong>Range</strong>: 0 – 0.1 × 10 3 /μL<br />

Optimal <strong>Range</strong>: 0 – 0.1 × 10 3 /μL


Dealing With High/Low Immature<br />

Granulocytes<br />

High or low immature granulocytes indicates<br />

the need for additional testing to determine<br />

which type(s) of white blood cell is affected<br />

The cause and treatment will depend on<br />

whether monocytes, eosinophils or basophils<br />

are the ones affected<br />

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