Hyperbaric Oxygen Therapy - Hyperbaric Chamber Information ...
Hyperbaric Oxygen Therapy - Hyperbaric Chamber Information ...
Hyperbaric Oxygen Therapy - Hyperbaric Chamber Information ...
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the identified studies. Until more rigorous evidence is collected, the use of HBOT in the<br />
management of these conditions cannot be supported on the basis of the current<br />
inconsistent results.<br />
Cancer: head and neck<br />
The identified studies were disparate in their research designs, varied in their populations,<br />
discrepant in their therapies, and conflicting in their outcomes and conclusions. Overall,<br />
there is a lack of well-conducted studies to support the use of hyperbaric oxygen therapy<br />
for head and neck cancer and there is little firm evidence of a beneficial effect.<br />
Cancer: cervix<br />
The studies failed to provide enough evidence to come to firm conclusions about the<br />
effectiveness of exposure to HBO in conjunction with radiotherapy for cervical cancer.<br />
Any conclusions reached from these studies would need to take into consideration the<br />
disparity in intervention and comparison protocols, poor methodological descriptions,<br />
and substantial post-hoc comparisons.<br />
Cancer: bladder<br />
There are conflicting results about the survival benefit afforded by exposure to HBOT in<br />
conjunction with radiotherapy for bladder cancer. The lack of methodological rigour, the<br />
variations in protocols, and inadequate descriptions of populations make it difficult to<br />
arrive at a global assessment of effectiveness.<br />
Cancer: lymphomas<br />
A single study provides some evidence of the efficacy of HBOT in the treatment of<br />
lymphomas. The validity of the end-points used is unclear. The generation of evidence<br />
from properly randomised clinical trials that focus on other outcomes is needed to<br />
support or refute the effectiveness of HBOT for this indication.<br />
Cancer: lung<br />
A single study provides little evidence of the effect of HBOT in the treatment of lung<br />
cancer. More studies in different settings and examining more varied outcomes are<br />
required to reach more generalisable evidence of effect.<br />
Cancer: neuroblastoma<br />
While this study provides some evidence of the effect of HBOT in the treatment of<br />
neuroblastoma, the use of this technology cannot be supported until more rigorous<br />
evidence is collected.<br />
Carbon monoxide poisoning<br />
A Cochrane systematic review failed to demonstrate a significant reduction in neurologic<br />
sequelae following HBOT for carbon monoxide poisoning. Additional rigorous studies<br />
are required to examine the efficacy of HBOT on other outcomes and in distinct patient<br />
subsets.<br />
xiv <strong>Hyperbaric</strong> oxygen therapy