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Sudden deafness and acoustic trauma<br />

First Author and<br />

Year<br />

of Publication<br />

Cavallazi 1996 95<br />

Vavrina 1995 96<br />

Hoffmann 1993 97<br />

(acute)<br />

Hoffmann 1993 98<br />

(chronic)<br />

NHMRC<br />

Level<br />

Study Design Location<br />

Dates of<br />

Enrolment Size<br />

Characteristics of Study Population †<br />

Age (years)<br />

Mean (SD)<br />

Sex Ratio<br />

(M:F)<br />

III-2 Comparative study Italy ? ‡ 62 48.2 (29-70) § 32:30<br />

III-2 Comparative study<br />

Switzerlan<br />

d<br />

? 78<br />

I=24.9 (6.3)<br />

C=22.7 (7.6)<br />

II RCT Germany ? 20 ? ?<br />

II RCT Germany ? 44 ? ?<br />

* Abbreviations: C = comparison group, F = female, I = intervention group, M = male, RCT = randomised controlled trial, SD = standard<br />

deviation.<br />

† <strong>Information</strong> is given for intervention and comparison groups, if available. Otherwise, total study population values are stated.<br />

‡ Unstated, unclear, or unknown.<br />

§ Figures in parentheses are ranges.<br />

Cancer: head and neck<br />

First Author and<br />

Year of Publication<br />

Whittle 1990 99<br />

Henk 1986 100<br />

Sealy 1986 101<br />

Berry 1979 102<br />

Sause 1979 103<br />

Chang 1973 104<br />

Churchill-Davidson<br />

1973 105<br />

Shigamatsu 1973 106<br />

Henk 1970 107<br />

NHMRC<br />

Level<br />

Study Design Location<br />

Dates of<br />

Enrolment Size<br />

Characteristics of Study Population †<br />

Age (years)<br />

Mean (SD)<br />

III-2 Comparative study UK 1963 to 1985 397 ? ‡ ?<br />

II RCT UK 1972 to 1977 107 ? ?<br />

II RCT<br />

South<br />

Africa<br />

II RCT UK<br />

II RCT USA<br />

II RCT USA<br />

III-3<br />

III-1<br />

III-1<br />

Comparative study<br />

with historical<br />

controls<br />

Pseudorandomised<br />

controlled trial<br />

Pseudorandomised<br />

controlled trial<br />

Sep 1980 to<br />

Mar 1984<br />

Jan 1971 to<br />

Dec 1974<br />

Nov 1970 to<br />

Dec 1976<br />

Jan 1964 to<br />

Mar 1971<br />

102 <strong>Hyperbaric</strong> oxygen therapy<br />

130<br />

24<br />

50<br />

I=56<br />

C=55<br />

I=61 (6)<br />

C=66 (9)<br />

I=57 (38-80) §<br />

C=63 (36-81)<br />

?<br />

Sex Ratio<br />

(M:F)<br />

I=56:8<br />

C=60:6<br />

?<br />

I=8:13<br />

C=15:8<br />

51 ? 2.5:1<br />

UK 1962 to 1972 171 ? ?<br />

Japan 1969 to 1971 42<br />

UK<br />

Sep 1964 to<br />

Jun 1969<br />

213<br />

I=56.6<br />

C=57.7<br />

I=60<br />

C=58<br />

?<br />

I=76:25<br />

C=71:41<br />

* Abbreviations: C = comparison group, F = female, I = intervention group, M = male, RCT = randomised controlled trial, SD = standard<br />

deviation.<br />

† <strong>Information</strong> is given for intervention and comparison groups, if available. Otherwise, total study population values are stated.<br />

‡ Unstated, unclear, or unknown.<br />

§ Figures in parentheses are ranges.

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