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Hyperbaric Oxygen Therapy - Hyperbaric Chamber Information ...

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Sensitivity analysis<br />

Table 83 shows the results of the sensitivity analysis varying the efficacy of the<br />

comparator group using the 95% CI, costs of a doctor in attendance during treatment,<br />

varying the number of HBOT sessions per patient and the number of chambers in the<br />

facility.<br />

Table 83 Sensitivity analysis – osteoradionecrosis<br />

Sensitivity Analysis Incremental cost per case of osteoradionecrosis avoided<br />

$28,480 – primary case<br />

15.87% of patients in the comparator group with<br />

$66,187<br />

osteoradionecrosis (lower 95% CI)<br />

46.98% of patients in the comparator group with<br />

osteoradionecrosis (upper 95% CI)<br />

Cost of doctor/specialist covered by cost of patient<br />

assessment prior to a course of HBOT treatment<br />

$16,663<br />

$18,438<br />

15 HBOT sessions per patient $14,212<br />

40 HBOT sessions per patient $37,991<br />

Operating costs shared between 2 HBOT units $16,214<br />

Operating costs shared between 4 HBOT units $10,081<br />

Table 83 shows that if the staff requirements of a hyperbaric nurse, technician and<br />

physician are shared among four HBOT chambers in a hyperbaric facility, the<br />

incremental cost per case of osteoradionecrosis avoided is $10,081. The incremental cost<br />

per case of osteoradionecrosis avoided is $66,187, using the lower limit of the 95% CI<br />

for the efficacy of the comparator group, keeping the efficacy of the HBOT group fixed.<br />

Summary<br />

The incremental treatment cost per case of osteoradionecrosis avoided is estimated to be<br />

$28,480, in patients who had an indication for removal of one or more teeth in a segment<br />

of the mandible. Sensitivity analysis suggests a range of $10,081-$66,187 per case of<br />

osteoradionecrosis avoided.<br />

Conclusions<br />

The indicative cost-effective ratios estimated for a small number of indications i.e.<br />

HBOT in diabetic wounds, necrotising soft tissue infections, and osteoradionecrosis, are<br />

summarised in Table 84.<br />

Table 84 Summary of indicative cost-effectiveness ratios in four indications<br />

Diabetic Wounds<br />

- Incremental Cost per Amputation Avoided $22,054 (cost saving to $63,100)<br />

Non-Diabetic Wounds<br />

Treatment cost of $6,941 per patient for a one third<br />

- Reduction in Wound Area<br />

reduction in wound area<br />

Incremental Cost per Death Avoided<br />

- Necrotising Soft Tissue Infections<br />

$16,105 ($5,368-$71,557)<br />

Incremental Cost per Case of Osteoradionecrosis Avoided $28,480 ($10,081-$66,187)<br />

In addition:<br />

<strong>Hyperbaric</strong> oxygen therapy 89

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