Prime User Manual - ISP
Prime User Manual - ISP
Prime User Manual - ISP
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Chapter 3: <strong>Prime</strong>–Structure Prediction: Initial Steps<br />
<strong>Prime</strong> 2.1 <strong>User</strong> <strong>Manual</strong><br />
Figure 3.5. The Find Homologs step with search results.<br />
If structure alignment fails or does not give the intended result, the problem may be one of the<br />
following:<br />
• The selected templates are structurally too dissimilar for a meaningful alignment.<br />
• One or more of the template structures includes multiple chains, and either<br />
• Two or more templates are chains from one .pdb file (the structure alignment facility<br />
will not align chains from the same file), or<br />
• The chains that were aligned were not the chains you intended to align.