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Gastric Digestion of Foods—Challenges and Opportunities for Food ...

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Stomach<br />

• Volume: 50ml to 4 liters <strong>of</strong> liquid<br />

• From an engineering perspective, the human<br />

stomach is a receptacle, a grinder, a mixer <strong>and</strong> a<br />

pump that controls the digestion process<br />

– Chemical digestion by enzyme activity<br />

– Mechanical digestion by the mixing in the stomach<br />

• <strong>Gastric</strong> juice: Colorless fluid<br />

– 1.5 L secreted/d<br />

• Hydrochloric acid<br />

– breaks the food apart <strong>and</strong> kills most <strong>of</strong> the bacteria<br />

that you swallow<br />

• Mucus (~1.5 g/L)<br />

– <strong>for</strong>ms a gelatinous coating over the mucosal surface.<br />

• Pepsin (~ 1 g/L)<br />

– proteins broken down into smaller polypeptide chains<br />

• Salt, <strong>Gastric</strong> Lipase<br />

– fat digestion begins here

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