Gastric Digestion of Foods—Challenges and Opportunities for Food ...
Gastric Digestion of Foods—Challenges and Opportunities for Food ...
Gastric Digestion of Foods—Challenges and Opportunities for Food ...
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In Vitro Dissolution Testing <strong>of</strong> Oral<br />
Dosage Forms: USP apparatus<br />
• Apparatus 1 - Basket (37º)<br />
• Apparatus 2 - Paddle (37º)<br />
• Apparatus 3 - Reciprocating Cylinder (37º)<br />
• Apparatus 4 - Flow-Through Cell (37º)<br />
• 500 ml –1000 ml (900 ml)<br />
• Agitation speed: 50-100 rpm <strong>for</strong> basket method, <strong>and</strong> 25-75 rpm <strong>for</strong><br />
paddle method.<br />
• Aqueous dissolution medium composed <strong>of</strong> 0.1 N HCl (or pH 1.2)