Biomedical Engineering – From Theory to Applications

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388 Biomedical Engineering – From Theory to Applications Rebouças J.S.; DeFreitas-Silva G.; Idemori Y.M., Spasojević I., Benov L., Batinić-Haberle I. (2008a). Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier. Free Radical Biology & Medicine Vol. 45 No 2 (July 15), pp. 201–210, ISSN 0891-5849, doi: 10.1016/j.freeradbiomed.2008.04.009. Rebouças J.S., Spasojević I., Tjahjono D.H., Richaud A., Mendez F., Benov L., Batinić-Haberle I. (2008b). Redox modulation of oxidative stress by Mn porphyrin-based therapeutics: the effect of charge distribution. Dalton Transactions, No.9, pp. 1233– 1242, ISSN 1477-9226, doi: 10.1039/B716517J Rees J.R.E., Lao-Sirieix P., Wong A., Fitzgerald R.C. (2010). Treatment for Barrett’s oesophagus. Cochrane Database of Systematic Reviews Issue 1. Art. No.: CD004060. doi: 10.1002/14651858.CD004060.pub2 Renner M.W., Miura M., Easson M.W., Vicente M.G.H. (2006). Recent progress in the syntheses and biological evaluation of boronated porphyrins for boron neutroncapture therapy. Anticancer Agents Medicinal Chemistry Vol. 6 No.2 (October 31), pp. 145–157, ISSN: 1871-5206, doi: 10.1002/chin.200644231 Rosenthal M.A., Kavar B., Uren S., Kaye A.H. (2003). Promising survival in patients with high-grade gliomas following therapy with a novel boronated porphyrin. Journal of Clinical Neuroscience Vol. 10 No. 4 (July), pp. 425-427, ISSN 0967-5868, doi: 10.1016/S0967-5868(03)00062-6. Rothemund P. (1936). A New Porphyrin Synthesis. The Synthesis of Porphin. Journal of American Chemists Society, vol. 58, No. 4 pp. 625-627, ISSN 0002-7863, doi: 10.1021/ja01295a027. Rothemund, P. (1939). Porphyrin studies. III. The structure of the porphine ring system Journal of American Chemists Society Vol. 61 No. 10, pp. 2912-2015, ISSN 0002-7863 Salvemini D., Little J., Doyle T., Neumann W. (2011). Roles of reactive oxygen and nitrogen species in pain. Free Radical Biology & Medicine, ISSN 0891-5849, doi:10.1016/j.freeradbiomed.2011.01.026 (Epub ahead of print). Salvemini D., Neumann W. (2009). Targeting peroxynitrite driven nitroxidative stress with synzymes: A novel therapeutic approach in chronic pain management. Life Sciences Vol. 86 No. 15-16 (April 10), pp. 604-614, ISSN 0024-3205, doi: 10.1016/j.lfs.2009.06.011 Santos P.F., Reis L.V., Almeida P., Oliveira A.S., Vieira Ferreira L.F., Singlet oxygen generation ability of squarylium cyanine dyes, J.Photochem. Photobiol. A: Chem. 160 (2003) pp. 159–161. ISSN 09380856, doi: 10.1013/j.bmc.2005.03.062 Santos P.F., Reis L.V., Almeida P., Serrano J.P., Oliveira A.S., Vieira Ferreira L.F., Efficiency of singlet oxygen generation of aminosquarylium cyanines, J.Photochem. Photobiol. A: Chem. 163 (2004) pp. 267–269. ISSN 0001-4845, 25 doi: 10.1011/ar0300012 Schneider R.; Schmitt F.; Frochot C.; Fort Y.; Lourette N.; Guillemin F.; Müller J.F.; Barberi- Heyob M. (2005). Design, synthesis, and biological evaluation of folic acid targeted tetraphenylporphyrin as novel photosensitizers for selective photodynamic therapy, Bioorganic & Medicinal Chemistry, Vol 13 No. 8 (April 15), pp. 2799-808,. ISSN 09680896, doi: 10.1016/j.bmc.2005.02.025
Trends in Interdisciplinary Studies Revealing Porphyrinic Compounds Multivalency Towards Biomedical Application Senge M.O. (2005). Nucleophilic Substitution as a Tool for the Synthesis of Unsymmetrical Porphyrins. Accounts of Chemical Research Vol. 38 No. 9, 733-743, ISSN 0001-4842, doi: 10.1021/ar0500012 Senge M.O., Shaker Y.M., Pintea M., Ryppa C., Hatscher S.S., Ryan A., Sergeeva Y., (2010). Synthesis of meso-substituted ABCD-type porphyrins by functionalization reactions. European Journal of Organic Chemistry No.2 (January), pp. 237-258, ISSN 1434-193X, doi: 10.1002/ejoc.200901113 Sessler J.L., Weghorn S.J., Lynch V., Johnson M.R. (1994a). Turcasarin, The Largest Expanded Porphyrin Prepared to Date. Angewandte Chemie International Edition English, vol. 33, pp. 1509-1512, ISSN. 1433-7851 Sessler J.L.; Brucker E.A.; Weghorn S.J.; Kisters M.; Schäfer M., Lex J., Vogel E. (1994b). Corrphycene: A New Porphyrin Isomer. Angewandte Chemie International Edition English, vol. 33, pp. 2308-2312, ISSN. 1433-7851 Sessler J.L., Davis JM, Lynch V. (1998). Synthesis and Characterization of a Stable Smaragdyrin Isomer. Journal of Organic Chemistry Vol. 60 No. 23 (September), pp. 7062-7065, ISSN 1434-193X, doi: 10.1021/jo981019b Shahbazi-Gahrouei D., Williams M., Rizvi S., Allen B.J. (2001). In vivo studies of Gd-DTPAmonoclonal antibody and Gd-porphyrins: potential magnetic resonance imaging contrast agents for melanoma. Journal of Magnetic Resonance Imaging, Vol.14 No.2 (August), pp. 169-174, ISSN 1053-1807, doi: 10.1002/jmri.1168. Song R.; Kim Y.S.; Sohn Y.S. (2002). Synthesis and selective tumor targeting properties of water soluble porphyrin-Pt(II) conjugates, Journal Inorganic Biochemistry. Vol. 89 No. 1-2 (April 10) pp.83-88, ISSN 0162- 0134, doi: 10.1016/S0162-0134(01)00413-5. Sortino S. (2008). Nanostructured molecular films and nanoparticles with photoactivable functionalities. Photochemical & Photobiological Sciences, Vol. 7, pp. : 911-924, ISSN 1474-905X, doi: 10.1039/B807353H. Spikes J.D. (1989). Photosensitization. In The Science of Photobiology. Photosensitization, Smith K.S. (Ed.), pp. 79-110. Plenum Press, ISBN 978-0306430596 New York, London. Tang H.M., Hamblin M.R., Yow C.M. (2007). A comparative in vitro photoinactivation study of clinical isolates of multidrug-resistant pathogens. Journal of Infection and Chemotherapy Vol 13 No.2 (April), pp. 87-91, ISSN 1341-321X, doi: 10.1007/s10156- 006-0501-8. van Duijnhoven F.H., Aalbers R.I., Rovers J.P., Terpstra O.T., Kuppen P.J. (2003). The immunological consequences of photodynamic treatment of cancer, a literature review. Immunobiology Vol. 207 No. 2, pp. 105-113, ISSN 0171-2985, doi: 10.1078/0171-2985-00221. Verma S., Watt G.M., Mai Z., Hasan T. (2007). Strategies for enhanced photodynamic therapy effects Photochemistry & Photobiology Vol 83 No. 5 (September/October) pp. 996-1005, ISSN 0031-8655, doi: 10.1111/j.1751-1097.2007.00166.x Vicente M.G.H. (2001). Porphyrin-based sensitizers in the detection and treatment of cancer: recent progress. Current Medicinal Chemistry - Anti-Cancer Agents Vol. 1, No. 2 (August), pp. 175-194, ISSN 1568-0118. Vicente M.G.H., Wickramasighe A., Nurco D.J., Wang H.W.H., Nawrocky M.M., Makar M.S., Miura M. (2003). Syntheses, toxicity and biodistribution of two 5,15-di[3,5- (nido-carboranyl-methyl)phenyl]porphyrin in EMT-6 tumor bearing mice. 389
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BIOMEDICAL ENGINEERING - FROM THEOR
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free online editions of InTech Book
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VI Contents Chapter 9 Targeted Magn
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X Preface stand-alone and readers c
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2 Biomedical Engineering - From The
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4 Fig. 2. Process for retrieval inf
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6 Biomedical search engine Scientif
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10 Biomedical Engineering - From Th
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12 Bireme http://regional.bv salud.
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14 Semantic Networks analysis Biome
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108 Method (Detection) CIEF-tITP-CZ
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110 Method (Detection) Analyte Matr
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120 6. Conclusion Biomedical Engine
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150 5. Conclusions Biomedical Engin
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162 1 st phase : half year 4 2 nd p
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166 7. Innovative active training B
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172 12. Maturing projects’ story
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180 16. Acknowledgments Biomedical
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190 R* M M M M MR*M O O O O M O R*
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196 Fig. 9. Chemical structure of 5
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198 Relative Intensity (AU) Biomedi
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204 2. Preparation of IO nanopartic
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256 3. Deposition techniques Biomed
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300 2. Nanoparticles in biomedical
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454 In this case, the eigenvalues a
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472 Nb b b l l1 Biomedical Engineer
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