2012 Promega catalogue

Life
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2012
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Cell Signaling
Protein Deamidation Detection
182
ISOQUANT ® Isoaspartate Detection Kit
Product Size Cat.# Price ($)
ISOQUANT ® Isoaspartate Detection Kit 100 assays MA1010 2004.00
For Research Use Only. Not for Use in Diagnostic Procedures.
Description: The ISOQUANT ® Isoaspartate Detection Kit is intended for
quantitative detection of isoaspartic acid residues in proteins and peptides,
which can result from the gradual, nonenzymatic deamidation of asparagine or
rearrangement of aspartic acid residues during storage or handling. Because
the kit does not depend on the monitoring of charge differences for detection,
charge heterogeneity does not interfere with the assay. The ISOQUANT ® Kit can
be used on peptides or proteins such as monoclonal antibodies.
Features:
• Great Efficiency: Simple procedure with a test time of less than one hour.
Automation possible with HPLC autosampler capability.
• Economical: HPLC detection eliminates cost and inconvenience of
radioactive materials handling.
• Analytical: Quantitative results available.
• Versatile: Perform individual samples or batches. Small sample size
makes the assay suitable for research, analytical methods, formulations
and process development work.
• Robust: Not affected by common buffer components.
• HPLC Detection Method: Fits with existing equipment and expertise.
• Sensitive: Detects isoaspartate resulting from aspartic acid rearrangement
as well as deamidation of asparagine.
Storage Conditions: Store at –20°C.
Protocol Part#
ISOQUANT ® Isoaspartate Detection Kit Technical Bulletin
TBI001
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