Development of a Bioluminescent Cell-Based Assay to ... - Promega
Development of a Bioluminescent Cell-Based Assay to ... - Promega
Development of a Bioluminescent Cell-Based Assay to ... - Promega
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ADCC Reporter Bioassay is robust<br />
Fold <strong>of</strong> Induction<br />
Fold <strong>of</strong> Induction<br />
30<br />
20<br />
10<br />
0<br />
-10 -9 -8 -7 -6 -5<br />
Log10 [B1 antibody], g/ml<br />
30<br />
20<br />
10<br />
1<br />
0<br />
-10 -9 -8 -7 -6 -5<br />
Log10 [B1 antibody], g/ml<br />
Confidential and Proprietary. Not for Further Disclosure.<br />
Time <strong>of</strong> induction<br />
1<br />
6<br />
7<br />
14<br />
1<br />
7<br />
13<br />
16<br />
Run Hr induction EC50<br />
1 6 hr 3.15 x 10e-8 g/ml<br />
2 5.5 hr 3.83 x 10e-8 g/ml<br />
E:T ratio and cells/well<br />
Run E:T ratio T cells E cells EC50<br />
1 7.5:1 10K 75K 3.09 x 10e-8 g/ml<br />
2 6:1 15K 90K 3.83 x 10e-8 g/ml
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