Development of a Bioluminescent Cell-Based Assay to ... - Promega
Development of a Bioluminescent Cell-Based Assay to ... - Promega
Development of a Bioluminescent Cell-Based Assay to ... - Promega
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A new bioassay for Fc effec<strong>to</strong>r functionality in ADCC<br />
Highlights <strong>of</strong> a novel bioluminescent cell-based bioassay:<br />
A cell-based bioassay <strong>to</strong> quantify potency <strong>of</strong> Fc effec<strong>to</strong>r<br />
function in ADCC MOA pathway<br />
<strong>Based</strong> on target cell-bound antibody activation <strong>of</strong> FcgIIIa<br />
recep<strong>to</strong>r signaling pathways in the effec<strong>to</strong>r cell<br />
<strong>Bioluminescent</strong> NFAT-RE-luciferase reporter bioassay readout<br />
is in engineered effec<strong>to</strong>r cells<br />
Confidential and Proprietary. Not for Further Disclosure.<br />
The bioassay is robust, specific, precise and accurate<br />
Suitable for stability studies, lot release and antibody characterization<br />
Effec<strong>to</strong>r cells are reagents -in frozen, thaw-and-use format<br />
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