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Analysis Method Reference range Requirement Comments<br />

Cotinine<br />

GC/MS non-smoker < 5 µg/l<br />

passive smoker < 85 µg/l<br />

smoker > 200 µg/l<br />

non-smoker < 5 µg/l<br />

passive smoker < 85 µg/l<br />

smoker 45 - 524 µg/l<br />

saliva 1 ml<br />

urine 10 ml<br />

serum 2 ml<br />

meconium 1 g<br />

Coumarins GC/MS urine 20 ml<br />

Coxiella burneti complement<br />

binding reaction<br />

Creatine<br />

Creatine kinase<br />

Creatinine<br />

< 1 : 10<br />

photometry (UV) women 19 - 270 mg/d<br />

men 11 - 189 mg/d<br />

photometry (UV) women < 140 U/l<br />

men < 170 U/l<br />

infant up to 7 days < 650 U/l<br />

infant up to 30 days < 290 U/l<br />

children up to 1 year < 200 U/l<br />

photometry adults < 1.20 mg/dl<br />

up to 1 month < 1.20 mg/dl<br />

7 - 12 month < 1.00 mg/dl<br />

0.4 - 2.6 g/l<br />

1.0 - 2.5 g/d<br />

13th - 20th week of gestation 0.4 - 0.8 mg/dl<br />

21st - 34th week of gestation 0.9 - 2.0 mg/dl<br />

serum 1 ml<br />

urine 5 ml<br />

P: Sample of 24-hour collection<br />

serum 1 ml<br />

serum 1 ml<br />

urine 5 ml<br />

amniotic liquor 1 ml<br />

Metabolite of nicotine<br />

Acenocoumarol, Cumarin, Cumatetralyl,<br />

Phenoprocoumon and Warfarin are<br />

detected<br />

Isoenzymes: see creatinine kinaseisoenzymes<br />

Page 37

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