IMS Company Profiles - Report Buyer
IMS Company Profiles - Report Buyer IMS Company Profiles - Report Buyer
IMS COM PANY PRO FILES NOVARTIS Company/Organization Date Area of Collaboration Terms of Agreement Immusol 2005 Target identification Three-year discovery, development and commercialization agreement to use Immusol’s gene-activation technology to discover targets, which Novartis might elect to use for the development of pharmaceuticals. Avalon 2005 Drug discovery Agreement to develop small-molecule drug using Avalon’s drug-discovery engine and product candidates in Novartis’ chemical library. Milestone achieved in January 2008. Immusol 2005 Drug discovery Three-year discovery, development and commercialization collaboration. Immusol will leverage its gene activation technology to discover biologically validated drug targets for Novartis. Idera (formerly Hybridon) 2005 Drug discovery Research collaboration and license deal for the discovery, optimization, development and commercialization of Toll-like receptor 9 drug candidates targeting asthma and allergy based on Hybridon’s proprietary immune modulatory oligonucleotide (IMO) technology platform. Galapagos 2005 Design research programs Agreement to use Galapagos’ genomics services division’s SilenceSelect target discovery system. Conor Medsystems 2005 Drug-coated stents Conor will test three Novartis products (Glivec, Elidel and midostaurin) for use with future stents for the treatment of clogged heart arteries. If one of the compounds proves successful, Conor has the option to obtain a worldwide, non-exclusive license to commercialize products combining the compound and its stents. © 2009 IMS Health In cor po rated or its af fil i ates Page 134
IMS COM PANY PRO FILES NOVARTIS Company/Organization Date Area of Collaboration Terms of Agreement Compugen 2005 Systems biology Pilot research project in the field of systems biology. Compugen will generate information about biological interaction network through the development of a proprietary platform for research and analysis of microarray and other biological data. Novartis will obtain sole rights to the specific results of the project, and Compugen will retain all rights to the research and discovery systems developed through the collaboration. ESBATech 2005 Drug discovery Collaboration on the discovery of receptor tyrosine kinase inhibitors using ESBATech’s cellular HTS technology for inhibitor identification. ESBATech will receive up-front and milestone payments and research funding. Biotech (Thailand’s National Center for Genetic Engineering and Biotechnology) 2005 Natural products Agreement with the Thai government to develop new medicines based on natural herbs found in Thailand. Biotech will receive technology transfer and financial contributions. Avanir 2005 Inflammation drugs Global research, development and commercialization agreement to develop orally active small molecules therapeutics targeting macrophage migration inhibitory factor (MIF) as potential treatments for inflammatory diseases. Avanir will receive over $200m in combined upfront and milestone payments, plus royalties and funding of up to $2.5m per year for up to four years. Infinity 2005 Chemical drug development © 2009 IMS Health In cor po rated or its af fil i ates Page 135 Two-year collaborative agreement for development of small molecules for the potential treatment of undisclosed indications. The molecules are to be designed by both companies, and synthesized using Infinity’s diversity-oriented synthesis technology.
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<strong>IMS</strong> COM PANY PRO FILES NOVARTIS<br />
<strong>Company</strong>/Organization Date Area of<br />
Collaboration<br />
Terms of Agreement<br />
Compugen 2005 Systems biology Pilot research project in the field of<br />
systems biology. Compugen will generate<br />
information about biological interaction<br />
network through the development of a<br />
proprietary platform for research and<br />
analysis of microarray and other biological<br />
data. Novartis will obtain sole rights to the<br />
specific results of the project, and<br />
Compugen will retain all rights to the<br />
research and discovery systems developed<br />
through the collaboration.<br />
ESBATech 2005 Drug discovery Collaboration on the discovery of receptor<br />
tyrosine kinase inhibitors using<br />
ESBATech’s cellular HTS technology for<br />
inhibitor identification. ESBATech will<br />
receive up-front and milestone payments<br />
and research funding.<br />
Biotech (Thailand’s<br />
National Center for<br />
Genetic Engineering and<br />
Biotechnology)<br />
2005 Natural products Agreement with the Thai government to<br />
develop new medicines based on natural<br />
herbs found in Thailand. Biotech will<br />
receive technology transfer and financial<br />
contributions.<br />
Avanir 2005 Inflammation drugs Global research, development and<br />
commercialization agreement to develop<br />
orally active small molecules therapeutics<br />
targeting macrophage migration inhibitory<br />
factor (MIF) as potential treatments for<br />
inflammatory diseases. Avanir will receive<br />
over $200m in combined upfront and<br />
milestone payments, plus royalties and<br />
funding of up to $2.5m per year for up to<br />
four years.<br />
Infinity 2005 Chemical drug<br />
development<br />
© 2009 <strong>IMS</strong> Health In cor po rated or its af fil i ates Page 135<br />
Two-year collaborative agreement for<br />
development of small molecules for the<br />
potential treatment of undisclosed<br />
indications. The molecules are to be<br />
designed by both companies, and<br />
synthesized using Infinity’s<br />
diversity-oriented synthesis technology.