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IMS Company Profiles - Report Buyer

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<strong>IMS</strong> COM PANY PRO FILES NOVARTIS<br />

<strong>Company</strong>/Organization Date Area of<br />

Collaboration<br />

Terms of Agreement<br />

ProMetic Biosciences 2006 Vaccines Agreement to develop synthetic-ligand<br />

affinity adsorbent for the purification of a<br />

recombinant protein vaccine. ProMetic will<br />

receive funding from Novartis. Financial<br />

details were not disclosed.<br />

Entelos 2006 Drug development Research in multiple disease areas.<br />

Novartis will provide R&D funding, while<br />

Entelos will conduct biosimulation<br />

research, which predicts the effects of<br />

drugs using “virtual patients”. The<br />

technology will provide more information<br />

for Novartis’ drug development, including<br />

the design of phase III clinical trial design.<br />

Financial terms were not disclosed.<br />

Momenta 2006 Biosimilars Agreement between Sandoz and Momenta<br />

to develop four follow-on and complex<br />

generic versions of previously approved<br />

recombinant biotechnology and complex<br />

drugs. Sandoz will make an initial<br />

payment of $75m for the purchase of<br />

approximately 4.7m shares of Momenta,<br />

which is also eligible to receive up to<br />

$188m in additional payments if all<br />

milestones are achieved.<br />

Cytopia 2006 Drug discovery Global license and R&D collaboration to<br />

develop orally active, small molecules<br />

therapeutics targeting JAK3 kinases for<br />

the prevention of transplant rejection and<br />

the treatment of multiple indications in<br />

autoimmune diseases such as rheumatoid<br />

arthritis. Novartis will assume<br />

responsibility for product development and<br />

commercialization. Cytopia has retained<br />

co-promotion rights for Australia and New<br />

Zealand.<br />

Genelabs 2006 Drug discovery Agreement for the development and<br />

commercialization of compounds from<br />

Genelabs’ HCV non-nucleoside drug<br />

discovery program. Genelabs will receive<br />

$20m over a planned two-year research<br />

program. Additional payments could<br />

exceed $175m. In 2008, Genelabs<br />

reported that the partnership was<br />

continuing to the next phase.<br />

© 2009 <strong>IMS</strong> Health In cor po rated or its af fil i ates Page 132

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