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<strong>IMS</strong> COM PANY PRO FILES NOVARTIS<br />
Product Class Date Terms of Agreement<br />
Starlix (nateglinide) A 1994 Licensed-in from Ajinomoto for marketing worldwide<br />
(except Japan, South Korea, Taiwan, China, the UK, and<br />
Ireland). In 1999, it acquired rights in the UK and Ireland.<br />
In 2000, Merck KGaA acquired co-promotion and<br />
co-marketing rights.<br />
Sandimmun (ciclosporin) L 1993 Licensed-out to Allergan for topical ophthalmic uses<br />
worldwide outside Japan and certain other Asian<br />
countries.<br />
Foradil (formoterol) R 1986 Licensed-in from Yamanouchi (now Astellas) by Ciba for<br />
all markets outside Japan.<br />
Xolair (omalizumab) R 1990 Novartis and Genentech share co-marketing rights in the<br />
USA.<br />
Lopresor/SR (metoprolol) C N/A Licensed-in from AstraZeneca for exclusive marketing in<br />
the USA, and non-exclusive marketing in other countries.<br />
Lotrel (amlodipine +<br />
benazepril)<br />
R&D Pipeline Products<br />
C N/A Pfizer granted Novartis rights to use amlodipine in<br />
combination with Novartis’ benazepril.<br />
Product Class Date Terms of Agreement<br />
IDX 899 J 2009 GlaxoSmithKline acquired exclusive global rights to<br />
Idenix’s reverse transcriptase inhibitor IDX 899. Idenoix<br />
is majority-owned by Novartis. All development of IDX<br />
899 and associated costs will be assumed by GSK. Upon<br />
successful commercialization, Idenix will receive double<br />
digit, tiered royalties on worldwide sales.<br />
elinogrel B 2009 Exclusive worldwide rights licensed-in from Portola<br />
Pharmaceuticals. Novartis will have responsibility for<br />
phase III trials, manufacturing and commercialization.<br />
Portola has an option to co-promote elinogrel in the US in<br />
the hospital and specialty markets and an option to<br />
co-fund phase III trials and other development activities<br />
in return for additional royalties.<br />
© 2009 <strong>IMS</strong> Health In cor po rated or its af fil i ates Page 126