IMS Company Profiles - Report Buyer

IMS Company Profiles - Report Buyer IMS Company Profiles - Report Buyer

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IMS COM PANY PRO FILES NOVARTIS Licensing/Co-Marketing Agreements Marketed Products Product Class Date Terms of Agreement Exforge (valsartan + amlodipine) C 2009 Co-promotion agreement for France with Ipsen. Galvus (vildagliptin) A 2008 Novartis Korea and HANDOK signed a co-promotion deal for South Korea. Simulect (basiliximab) L 2006 Cerimon acquired exclusive worldwide rights to basiliximab for the treatment of inflammatory bowel disease. Lescol (fluvastatin) and Lescol XL (fluvastatin extended release) C 1993- 2008 Elidel (pimecrolimus) L 2004- 6 Was co-marketed with Mitsubishi Tanabe in Japan under the terms of a 1993 deal, but this deal was terminated in 2008. AstraZeneca has rights in a number of markets. In 2001, German rights were licensed to Klinge and Fournier, which is now part of Solvay. In 2006, Biovail licensed-in rights to market Lescol and Lescol XL in Canada until 2008, and LG Pharma agreed to co-market the product in South Korea with Novartis. In 2004, Avantec Vascular obtained an option to license pimecrolimus for use in its drug-eluting stents. In 2006, Conor Medsystems obtained worldwide, non-exclusive license to pimecrolimus for use with its next-generation controlled vascular drug delivery technologies. Enablex (darifenacin) G 2005 Deal with Procter & Gamble for the co-promotion and further development of Enablex extended release tablets for the treatment of overactive bladder in the USA. Cibacen (benazepril)/Cibadrex (benazepril + HCT) C 2005 Meda AB granted exclusive rights in most European markets. Cubicin (daptomycin) J 2003 Chiron (now part of Novartis) acquired rights in Western Europe, Eastern Europe, the Middle East, Australia, New Zealand, Central America, South America and India. Certican (everolimus) L 2002 Novartis licensed everolimus to Guidant for use in Guidant’s stents. Later revised to give Guidant exclusivity, and the right to grant sub-licenses. © 2009 IMS Health In cor po rated or its af fil i ates Page 124

IMS COM PANY PRO FILES NOVARTIS Product Class Date Terms of Agreement Foradil Aerolizer (formoterol fumarate) Zaditen (ketotifen fumarate) Focalin (dexmethylphenidate) Estraderm MX/Estraderm TTS (17 beta estradiol) Famvir (famciclovir) and Vectavir/Denavir (penciclovir) Stalevo (entacapone + levodopa + carbidopa) Exelon (rivastigmine) N 1999- 2005 L 2002 Schering-Plough acquired US marketing & distribution rights for an upfront payment, milestones & royalties. N/C/R 2002 Canadian rights licensed to PanGeo Pharma. N 2000 Novartis licensed-in rights from Celgene for development and commercialization worldwide, outside Canada. G 2000 Japanese marketing transferred to Kissei. J 2000 Licensed-in from GlaxoSmithKline for worldwide markets. N 2000 Co-promotion and co-marketing deal with Orion. Originally licensed-in from Orion in 1998. In 2005, Novartis and Ono agreed to co-develop and co-market the rivastigmine transdermal patch in Japan. Rivastigmine was licensed-out to Esteve for co-marketing in Spain in 1999 by Novartis. Exteva co-markets it in Spain as Prometax. Diovan (valsartan) C 1999 Schwarz acquired co-marketing rights in Germany. Menarini co-markets in Italy. Novartis and Choong-Wae have a co-promotion agreement for South Korea. Vivelle (17 beta estradiol patch) G 1999 Novartis acquired rights in Europe and certain other countries. In 1998, Novartis and Noven established a jv, Vivelle Ventures (became Novogyne Pharmaceuticals in 1999), to market Vivelle in North America. Originally licensed out by Noven to Ciba for marketing in North America in 1991. Visudyne (verteporfin) S 1995 Verteporfin was discovered at the University of British Columbia and was co-developed by QLT PhotoTherapeutics and CIBA Vision. The University of British Colombia licensed verteporfin to QLT, which sublicensed it to CIBA Vision for worldwide co-development and co-marketing. The deal was expanded in 2000. Femara (letrozole) L 1994 Novartis and Chugai agreed to co-market in Japan. © 2009 IMS Health In cor po rated or its af fil i ates Page 125

<strong>IMS</strong> COM PANY PRO FILES NOVARTIS<br />

Product Class Date Terms of Agreement<br />

Foradil Aerolizer<br />

(formoterol fumarate)<br />

Zaditen (ketotifen<br />

fumarate)<br />

Focalin<br />

(dexmethylphenidate)<br />

Estraderm MX/Estraderm<br />

TTS (17 beta estradiol)<br />

Famvir (famciclovir) and<br />

Vectavir/Denavir<br />

(penciclovir)<br />

Stalevo (entacapone +<br />

levodopa + carbidopa)<br />

Exelon (rivastigmine) N 1999-<br />

2005<br />

L 2002 Schering-Plough acquired US marketing & distribution<br />

rights for an upfront payment, milestones & royalties.<br />

N/C/R 2002 Canadian rights licensed to PanGeo Pharma.<br />

N 2000 Novartis licensed-in rights from Celgene for development<br />

and commercialization worldwide, outside Canada.<br />

G 2000 Japanese marketing transferred to Kissei.<br />

J 2000 Licensed-in from GlaxoSmithKline for worldwide markets.<br />

N 2000 Co-promotion and co-marketing deal with Orion.<br />

Originally licensed-in from Orion in 1998.<br />

In 2005, Novartis and Ono agreed to co-develop and<br />

co-market the rivastigmine transdermal patch in Japan.<br />

Rivastigmine was licensed-out to Esteve for co-marketing<br />

in Spain in 1999 by Novartis. Exteva co-markets it in<br />

Spain as Prometax.<br />

Diovan (valsartan) C 1999 Schwarz acquired co-marketing rights in Germany.<br />

Menarini co-markets in Italy. Novartis and Choong-Wae<br />

have a co-promotion agreement for South Korea.<br />

Vivelle (17 beta estradiol<br />

patch)<br />

G 1999 Novartis acquired rights in Europe and certain other<br />

countries. In 1998, Novartis and Noven established a jv,<br />

Vivelle Ventures (became Novogyne Pharmaceuticals in<br />

1999), to market Vivelle in North America. Originally<br />

licensed out by Noven to Ciba for marketing in North<br />

America in 1991.<br />

Visudyne (verteporfin) S 1995 Verteporfin was discovered at the University of British<br />

Columbia and was co-developed by QLT<br />

PhotoTherapeutics and CIBA Vision. The University of<br />

British Colombia licensed verteporfin to QLT, which<br />

sublicensed it to CIBA Vision for worldwide<br />

co-development and co-marketing. The deal was<br />

expanded in 2000.<br />

Femara (letrozole) L 1994 Novartis and Chugai agreed to co-market in Japan.<br />

© 2009 <strong>IMS</strong> Health In cor po rated or its af fil i ates Page 125

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