Anti-BNIP3 (phospho S95) antibody (ab83940) (ab83940) - Abcam
Anti-BNIP3 (phospho S95) antibody (ab83940) (ab83940) - Abcam
Anti-BNIP3 (phospho S95) antibody (ab83940) (ab83940) - Abcam
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<strong>Anti</strong>-<strong>BNIP3</strong> (<strong>phospho</strong> <strong>S95</strong>) <strong>antibody</strong> <strong>ab83940</strong> 1<br />
Product Datasheet<br />
Overview<br />
Product name <strong>Anti</strong>-<strong>BNIP3</strong> (<strong>phospho</strong> <strong>S95</strong>) <strong>antibody</strong><br />
Description Rabbit polyclonal to <strong>BNIP3</strong> (<strong>phospho</strong> <strong>S95</strong>)<br />
Tested applications WB, IHC-P, IHC-Fr<br />
Cross reactivity Reacts with: Human<br />
Immunogen A synthetic peptide from the Human <strong>BNIP3</strong> conjugated to an immunogenic carrier protein.<br />
Properties<br />
Form Liquid<br />
Storage instructions Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50%, aliquot and store<br />
at -20°C. Avoid repeated freeze / thaw cycles.<br />
Storage buffer Preservative: None<br />
Constituents: PBS, Whole serum<br />
Purity Whole antiserum<br />
Clonality Polyclonal<br />
Isotype IgG<br />
Research Areas Metabolism Pathways and Processes Mitochondrial Metabolism<br />
Mitochondrial markers<br />
Metabolism Pathways and Processes Metabolism processes Hypoxia<br />
Metabolism Types of disease Cancer<br />
Metabolism Pathways and Processes Metabolism processes Apoptosis<br />
Cancer Cancer Metabolism Response to hypoxia<br />
Cardiovascular Heart Apoptosis<br />
Microbiology Interspecies Interaction Host Virus Interaction<br />
Cell Biology Apoptosis Intracellular Bcl2 Family<br />
Cell Biology Apoptosis Mitochondrial<br />
Applications<br />
Our Abpromise guarantee covers the use of <strong>ab83940</strong> in the following tested applications.<br />
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.<br />
Application Notes<br />
WB WB: 1/300 - 1/2000. Predicted molecular weight: 22 kDa. This <strong>antibody</strong> has been tested in Western<br />
blot against the recombinant peptide used as an immunogen. We have no data on detection of<br />
endogenous protein.<br />
IHC-P IHC-P: 1/300 - 1/2000. Perform heat mediated antigen retrieval before commencing with IHC<br />
staining protocol.<br />
IHC-Fr IHC-Fr: 1/300 - 1/2000.<br />
http://www.abcam.cn/<strong>BNIP3</strong>-<strong>phospho</strong>-<strong>S95</strong>-<strong>antibody</strong>-<strong>ab83940</strong>.html 1
<strong>Anti</strong>-<strong>BNIP3</strong> (<strong>phospho</strong> <strong>S95</strong>) <strong>antibody</strong> <strong>ab83940</strong> 2<br />
Target<br />
Function Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in<br />
repartitioning calcium between the two major intracellular calcium stores in association with<br />
BCL2.<br />
Sequence similarities Belongs to the NIP3 family.<br />
Cellular localization Mitochondrion. Mitochondrion membrane. Coexpression with the EIB 19-kDa protein results<br />
in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the<br />
mitochondria.<br />
Target information above from: UniProt accession Q12983 The UniProt Consortium<br />
The Universal Protein Resource (UniProt) in 2010<br />
Nucleic Acids Res. 38:D142-D148 (2010) .<br />
Database links Entrez Gene: 664 Human<br />
Omim: 603293 Human<br />
SwissProt: Q12983 Human<br />
Unigene: 144873 Human<br />
Alternative names<br />
BCL2 Adenovirus E1B 19kDa Interacting Protein 3 <strong>antibody</strong><br />
BCL2/adenovirus E1B 19 kDa protein interacting protein 3<br />
<strong>antibody</strong><br />
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3<br />
<strong>antibody</strong><br />
BNIP 3 <strong>antibody</strong><br />
<strong>BNIP3</strong> <strong>antibody</strong><br />
<strong>BNIP3</strong>_HUMAN <strong>antibody</strong><br />
NIP 3 <strong>antibody</strong><br />
NIP3 <strong>antibody</strong><br />
Our Abpromise to you: Quality guaranteed and expert technical support<br />
As standard<br />
Replacement or refund for products not performing as stated on the datasheet<br />
Valid for 6 months from date of delivery**<br />
Response to your inquiry within 24 hours<br />
In addition<br />
We provide support in Chinese, English, French, German, Japanese and Spanish<br />
Extensive multi-media technical resources to help you<br />
We investigate all quality concerns to ensure our products perform to the highest standards<br />
If the product does not perform as described on this datasheet, we will offer a refund or replacement. For full details of the Abpromise,<br />
please visit http://www.abcam.com/abpromise or contact our technical team.<br />
Terms and conditions<br />
Guarantee only valid for products bought direct from <strong>Abcam</strong> or one of our authorized distributors<br />
**Regional variations to our Abpromise may apply to the following countries: China, Korea, Singapore, Malaysia, Taiwan and Thailand,<br />
which operate a 120 day guarantee. Please contact your regional office for further details<br />
http://www.abcam.cn/<strong>BNIP3</strong>-<strong>phospho</strong>-<strong>S95</strong>-<strong>antibody</strong>-<strong>ab83940</strong>.html 2
<strong>Anti</strong>-<strong>BNIP3</strong> (<strong>phospho</strong> <strong>S95</strong>) <strong>antibody</strong> <strong>ab83940</strong> 3<br />
<strong>Anti</strong>bodies tested only in recombinant samples are not covered for use on endogenous samples. Please check the datasheet for<br />
information on tested species<br />
"Predicted to react" information on datasheets is based on sequence homology and provided for reference only<br />
"Predicted to react" species are not guaranteed, as they have not been tested<br />
Fast Track products are not covered under the Abpromise. Please see Fast Track terms and condition for additional information<br />
<strong>Abcam</strong> biochemicals are novel compounds and we have not tested their biological activity in house. Please use the literature to identify<br />
how to use these products effectively. If you require further assistance please contact the scientific support team<br />
Hong Kong office<br />
<strong>Abcam</strong> (香港)有限公司<br />
香港新界沙田香港科学园科技大道西8号尚湖楼7楼712室<br />
Tel: (852) 2603-6823<br />
Fax: (852) 3016-1888<br />
Email: hk.orders@abcam.com<br />
Visit us at: www.abcam.com<br />
http://www.abcam.cn/<strong>BNIP3</strong>-<strong>phospho</strong>-<strong>S95</strong>-<strong>antibody</strong>-<strong>ab83940</strong>.html 3