Apidra (insulin glulisine) - Sanofi Canada
Apidra (insulin glulisine) - Sanofi Canada
Apidra (insulin glulisine) - Sanofi Canada
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APIDRA should be administered by subcutaneous injection in the abdominal wall, the thigh, the<br />
buttock or the deltoid or by continuous subcutaneous infusion (CSII) in the abdominal wall. As<br />
with all <strong>insulin</strong>s, injection sites and infusion sites within an injection area (abdomen, thigh,<br />
buttock or deltoid) should be rotated from one injection to the next.<br />
As for all <strong>insulin</strong>s, the rate of absorption, and consequently the onset and duration of action, may<br />
be affected by injection site, exercise and other variables. Blood glucose monitoring is<br />
recommended for all patients with diabetes.<br />
Administration<br />
Preparation and Handling:<br />
APIDRA must only be used if the solution is clear, colourless, with no solid particles visible, and<br />
if it is of a water-like consistency. To minimize local irritation at the injection site, it is<br />
recommended to allow the <strong>insulin</strong> to reach room temperature before injection.<br />
The instructions for using the APIDRA in a pump or with an injection pen must be followed<br />
carefully.<br />
An empty vial, cartridge or SoloSTAR ® must never be reused and must be properly discarded.<br />
Vials<br />
Before withdrawing <strong>insulin</strong> from the vial for the first time, remove the plastic protective cap.<br />
Do not shake the vial vigorously as this may cause frothing. Froth may interfere with the correct<br />
measurement of the dose.<br />
Mixing of Insulins<br />
APIDRA can be mixed with NPH human <strong>insulin</strong> (except when administered with pump (see<br />
DOSAGE AND ADMINISTRATION, Continuous Subcutaneous Insulin Infusion pump)).<br />
If APIDRA is mixed with NPH human <strong>insulin</strong>, APIDRA should be drawn into the syringe first.<br />
Injection should be made immediately after mixing.<br />
No data are available on mixing APIDRA with <strong>insulin</strong> preparations other than NPH human<br />
<strong>insulin</strong>.<br />
Mixtures should not be administered intravenously.<br />
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