download report - Istituto Pasteur
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• Dendritic cells and leukocyte recruitment<br />
• Tumor immunology I<br />
• Leukocyte activation<br />
• Panomics<br />
• Th17: molecular, cellular and clinical aspects<br />
• Effector cells and regulatory molecules in allergy<br />
• Innate and adaptive immune interactions<br />
• Tumor Immunology II<br />
• Regulation of inflammatory response<br />
• Autoimmunity and regulation of immune<br />
response<br />
• Innate Immunity<br />
<strong>Istituto</strong> <strong>Pasteur</strong> Science Days<br />
The Contribution of Basic Science<br />
to Therapeutic Innovation<br />
Rome, October 23-24,2008<br />
Scientific Committee: L. Frontali, R. Silvestri, C. Turano<br />
• Gene therapy and stem cells<br />
Chairs: F. Chimenti, L. Frontali<br />
I. Bozzoni, RNA as a new therapeutic target: the<br />
case of Duchenne muscular dystrophy<br />
A. Giacomello, Adult heart stem cells<br />
F. Ascenzioni, Therapeutic artificial chromosomes<br />
• New vaccines<br />
Chairs: L. Frati, A. Santoni<br />
M. Pizza, From the genome to the identification of<br />
XIII<br />
REPORT OF ACTIVITY 2007-2008<br />
antigens for the development of new vaccines<br />
M.L. Bernardini, The vaccine against shigellosis:<br />
an ongoing challenge through hope and failure<br />
A. Saul, Developing vaccines for neglected diseases<br />
Award of the Gaia Luoni Prize 2008 on Genetics<br />
of susceptibility to malaria<br />
• New antitumoral drugs<br />
Chairs: V. Ziparo, C. Turano<br />
L. Pinna, Protein kinase CK2 as a potential target<br />
in the “Signal Transduction Therapy”<br />
R. Silvestri, Compounds that interact with<br />
tubulina: drugs today and future prospects<br />
R. Di Santo, Terminal transferase as a new<br />
therapeutic target against cancer: developing<br />
DKHA as specific inhibitors of TDT<br />
A. Brancale, The use of molecular modelling in<br />
designing new antitumoral agents<br />
A. Mai, Small molecules as epigenetic modulators<br />
of genic expression<br />
• Neurodegenerative diseases: towards<br />
therapeutical innovation<br />
Chairs: C. Falcone, A. Oliverio<br />
P. Puri, Drugs against muscular dystrophy<br />
F. Altieri, Neurodegenerative disease and<br />
oxidative stress: the involvement of proteindisolfuro-isomerasi<br />
L. Frontali, Mitochondrial models<br />
T. Rinaldi, Involvement of UPS system in<br />
neurodegenerative disease<br />
E.M. Valente, Pathogenetic mechanisms in<br />
Parkinsons disease: mitochondrions and more
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