download report - Istituto Pasteur
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P. Paggi - Neuronal response to experimental interruption of the neural circuit<br />
the plasminogen enzymatic cascade in the reaction<br />
to axotomy of rat sympathetic neurons. Mol Cell<br />
Neurosci. 2007, 36:174-84.<br />
90<br />
Lombardi L, De Stefano ME, Paggi P. Components<br />
of the NGF signaling complex are altered in mdx<br />
mouse superior cervical ganglion and its target<br />
organs. Neurobiol Dis. 2008, 32:402-11.<br />
Fig. 1 - Changes in plasmin(ogen) immunolabeling in control and injured (5 postoperative days) SCGs. (A-C and inset) Control SCG. (A)<br />
Plasmin(ogen) immunolabeling is scanty. At this magnification, blood vessels (arrows) are recognizable as the most immunopositive structures<br />
inside the ganglion. (B) At high magnification, immunopositive nerve fiber-like structures (arrowheads), bearing varicosities, are seen in<br />
between ganglionic neurons. (C and inset) Strongly immunopositive non-neuronal cells (double arrows) abut ganglionic neurons and emit<br />
long processes (arrowheads), which surround the neuronal perikaryon. (D) After post-ganglionic nerve crush, plasmin(ogen) immunolabeling<br />
increases notably, filling all the extracellular spaces. Scale bars: A, D: 50 µm; B, C and inset: 25 µm (De Stefano et al., 2007).