Pocket Program - CROI

CROI 2013 Session 125
c Tuesday, 2:30-4 pm; Hall B2
Session 124–Poster Abstracts
Innate Immunity and Hepatitis C Virus
696 Intra- and Extra-Hepatic Correlates of Plasma Viral
Clearance in Patients with Chronic Hepatitis C Virus
Eric Meissner* 1 , A Osinusi 1,2 , H Wang 3 , L Heytens 3 , A Nelson 1 ,
M Polis 1 , H Masur 3 , W Symonds 4 , A Fauci 1 , and S Kottilil 1
1 NIAID, NIH, Bethesda, MD, US;; 2 SAIC-Frederick, MD, US;; 3 Clinical
Ctr, NIH, Bethesda, MD, US;; and 4 Gilead Sci, Foster City, CA, US
697
Yu-Jin Lee* 1 , A Osinusi1,2 , M Kang3 , T Umbleja3 , V Amorosa4 ,
S Kottilil1 , M Peters5 , and ACTG5269 Study Group
1 2 3 NIH, Bethesda, MD, US;; SAIC-Frederick Inc, MD, US;; Harvard Sch of
Publ Hlth, Boston, MA, US;; 4VAMC, Philadelphia, PA, US;; and 5Univ of
California, San Francisco, US
698
C Virus Viral Clearance and Sustained Virological Response
in HIV/Hepatitis C Virus Co-infected Patients
Antonio Rivero-Juarez* 1 , R Gonzalez1 , A Camacho1 ,
B Manzanares-Martin1 , A Caruz2 , A Martinez-Peinado1 ,
L Martinez-Duenas1 , J Pineda3 , J Pena1 , and A Rivero1 1Inst Maimonides de Investigacion Biomed de Cordoba, Hosp Reina Sofia de
Cordoba, Spain;; 2Univ de Jaen, Spain;; and 3 708 Hepatitis C Virus Re-infections in HIV
Hosp de Valme, Seville, Spain
+ MSM: Evidence for
Partial Protective Immunity
X Thomas1 , B Grady2 , J van der Meer1 , F Lambers2 , M Prins1,2 ,
M van der Valk2 , S Rebers1 , R Molenkamp1 , Janke Schinkel* 1 ,
on behalf of MOSAIC Study Group
1 2 Academic Med Ctr, Amsterdam, The Netherlands and Publ Hlth Svc,
Amsterdam, The Netherlands
709 Trends in Prevalence of Hepatitis C Virus among the HIV +
Population: Spain
Sergio Serrano-Villar* 1 , P Sobrino-Vegas2 , M Riera3 , JA Iribarren4 ,
I Santos5 , R Rubio6 , L Munoz7 , B Clotet8 , J del Amo2 , S Moreno1 ,
and CoRIS
1 2 Hosp Univ Ramon y Cajal, Madrid, Spain;; Ctr Nacional de
Epidemiologia, Inst de Salud Carlos III, Madrid, Spain;; 3Hosp Univ Son
Espases, Palma, Spain;; 4Hosp Univ de Donostia, San Sebastian, Spain;;
5 6 Hosp Univ de la Princesa, Madrid, Spain;; Hosp Univ Doce de Octubre,
Madrid, Spain;; 7Hosp Univ San Cecilio, Granada, Spain;; and 8Hosp Univ
Germans Trias i Pujol, Badalona, Spain
704 Most Incident Hepatitis C Virus Infections among HIV +
Persons in a Contemporary Cohort Are Not Acquired
Parenterally
Lynn Taylor* 1 , T Bush 2 , P Patel 2 , K Henry 3 , L Conley 2 , J Hammer 4 ,
N Onen 5 , C Carpenter 1 , and J Brooks 2
1 Brown Univ, Providence, RI, US;; 2 CDC, Atlanta, GA, US;; 3 Hennepin
County Med Ctr, Minneapolis, MN, US;; 4 Denver Infectious Diseases
Consultants, CO, US;; and 5 Washington Univ, St Louis, MO, US
706 Acute Hepatitis C Virus Infection in Young Adults
Carrie Jennings* and K Sherman
Univ of Cincinnati Coll of Med, UC Hlth, OH, US
707 Location on HIV Phylogeny Is Indicative of the Risk of
Hepatitis C Virus Co-infection
Roger Kouyos* 1,2 , A Rauch 3 , V Aubert 4 , S Yerly 5 , J Boni 1 ,
T Klimkait 6 , B Ledergerber 1,2 , H Gunthard 1,2 , and Swiss HIV Cohort Study
1 Univ of Zurich, Switzerland;; 2 Univ Hosp Zurich, Switzerland;; 3 Univ of
Bern, Switzerland;; 4 Ctr Hosp Univ Vaudois, Lausanne, Switzerland;; 5 Univ
Hosp Geneva, Switzerland;; and 6 Univ of Basel, Switzerland
699
Clearance of Acute Hepatitis C in HIV + Patients
Pavlos Kokordelis* 1 , B Kramer1 , C Boesecke1 , C Korner1 , E Voigt2 ,
P Ingiliz3 , A Glassner1 , U Spengler1 , J Rockstroh1 , and J Nattermann1 1 2 Dept of Internal Med I, Bonn, Germany;; Praxis Theisen, Wiesel and Voigt,
Cologne, Germany;; and 3Med Ctr for Infectious Diseases, Berlin, Germany
700
Progression in HIV/Hepatitis C Virus Co-infected Patients
Andreas Glassner*, P Kokordelis, M Eisenhardt, B Kramer, F Wolter,
C Korner, C Boesecke, J Rockstroh, U Spengler, and J Nattermann
Univ of Bonn, Germany
701 HIV-associated Down-regulation of the Activating Natural
and Natural Course of Hepatitis C Virus Infection
Benjamin Kramer* 1 , P Kokordelis 1 , S Diegeler 1 , A Glassner 1 , M Eisenhardt 1 ,
P Ingiliz 2 , C Boesecke 1 , U Spengler 1 , J Rockstroh 1 , and J Nattermann 1
1 2 Univ of Bonn, Germany and Med Ctr for Infectious Diseases, Berlin,
Germany
702
Activity of Natural Killer Cells and May Be Involved in
Spontaneous Clearance of Acute Hepatitis C in HIV + Patients
Marianne Eisenhardt* 1 , A Glaessner1 , P Kokordelis1 , B Kraemer1 ,
F Wolter1 , E Voigt2 , C Boesecke1 , U Spengler1 , J Rockstroh1 ,
and J Nattermann1 1 2 Univ of Bonn, Germany and Ctr Theisen, Wiesel, and Voigt, Cologne,
Germany
703
Protein-10 in Patients Given an All-Oral Anti-Hepatitis C
Virus Regimen
Jennifer Lin* 1 , F Habersetzer2 , M Rodriguez-Torres3 , M Paulson4 ,
Y Zhu4 , M Subramanian4 , J McHutchison4 , M Sulkowski5 , D Wyles1 ,
and R Schooley1 1 2 Univ of California, San Diego, La Jolla, US;; Univ Hosp Strasbourg,
France;; 3Fndn de Investigacion de Diego, San Juan, Puerto Rico;; 4Gilead Sci, Inc, Foster City, CA, US;; and 5 710 Prevalence of Hepatitis C Virus Infection in US Hispanics/
Latinos: Results from the NHANES
Mark Kuniholm*
Johns Hopkins Univ Sch of Med,
Baltimore, MD, US
c Wednesday, 2:30-4 pm; Hall B2
Session 125–Poster Abstracts
Hepatitis C Virus Epidemiology and Clinical Outcomes
1 , M Jung1 , J Everhart2 , S Cotler3 , G Heiss4 ,
G McQuillan5 , B Thyagarajan6 , M Youngblood4 , R Kaplan1 , and G Ho1 1 2 Albert Einstein Coll of Med, Bronx, NY, US;; Natl Inst of Diabetes
and Digestive and Kidney Diseases, NIH, Bethesda, MD, US;; 3Univ of Illinois, Chicago, US;; 4Univ of North Carolina at Chapel Hill, US;;
5 6 CDC, Hyattsville, MD, US;; and Univ of Minnesota Med Ctr, Fairview,
Minneapolis, US
711 Diversity of Hepatitis C Virus Infection among HIV +
Drugs Users in India: Implications for HIV and Hepatitis C
Virus Treatment
Sunil Solomon* 1,2,3 , S Shanmugam2 , A Srikrishnan2 , S Iqbal2 ,
C Vasudevan2 , M Kumar2 , D Persaud1 , S Solomon2 , S Ray1 , and S Mehta3 1 2 Johns Hopkins Univ Sch of Med, Baltimore, MD, US;; YRG CARE,
Chennai, India;; and 3Johns Hopkins Univ Bloomberg Sch of Publ Hlth,
Baltimore, MD, US
712 Identifying Priorities for Improving Hepatitis C Virus Care
in the Era of Directly Acting Antiviral Therapy
Benjamin Linas* 1,2 , D Barter1 , J Leff3 , S Assoumou1 , A Kim4 ,
and B Schackman3 1 2 3 Boston Med Ctr, MA, US;; Boston Univ Sch of Publ Hlth, MA, US;; Weill
Cornell Med Coll, New York, NY, US;; and 4Massachusetts Gen Hosp,
Boston, US
713 Using an HIV Primary Care Model for the Treatment of
Hepatitis C
Lucas Hill*, C Ballard, B Colwell, D Wyles, F Torriani, W Mathews,
and E Cachay
Univ of California, San Diego, US
714
of Hepatitis C Virus Transmission: A Mathematical Model
Viviane Lima* 1 , B Nosyk1 , M Krajden2 , M Hull1 , T Kerr1 , E Wood1 ,
E Yoshida3 , Z Wu4 , and J Montaner1 1 2 BC Ctr for Excellence in HIV/AIDS, Vancouver, Canada;; BC Ctr
for Disease Control, Vancouver, Canada;; 3Univ of British Columbia,
Vancouver, Canada;; and 4Natl Ctr for AIDS/STD Control and Prevention,
Chinese Ctr for Disease Control and Prevention, Beijing
715 The Effect of Hepatitis C Virologic Clearance on Cardiovascular
Disease Biomarkers in HIV/Hepatitis C Virus Co-infection
Kara Chew* 1 , L Hua2 , D Bhattacharya1 , A Butt3,4 , R Chung5 ,
J Andersen2 , and J Currier1 1 2 David Geffen Sch of Med, Univ of California, Los Angeles, US;; Harvard
Sch of Publ Hlth, Boston, MA, US;; 3Univ of Pittsburgh Sch of Med, PA,
US;; 4Sheikh Khalifa Med City, Abu Dhabi, United Arab Emirates;; and
5Harvard Med Sch, Massachusetts Gen Hosp, Boston, US
716
Hepatitis C Virus and HIV/Hepatitis C Virus
Kara Chew*
705 Acute Hepatitis C Virus Infection in Studies of Elvitegravir/
Erin Quirk*, H Graham, H Liu, and J Szwarcberg
Gilead Sci Inc, Foster City, CA, US
1 , D Bhattacharya1 , K McGinnis2 , J Currier1 , and A Butt3,4 1 2 David Geffen Sch of Med, Univ of California, Los Angeles, US;; VA
Pittsburgh Hlthcare System, PA, US;; 3Univ of Pittsburgh Sch of Med, PA,
US;; and 4Sheikh Khalifa Med City, Abu Dhabi, United Arab Emirates
717 Methamphetamine Promotes Cardiac Dysfunction in
Genetically Engineered Hepatitis C Virus Mice
Rebecca Torres*, E Fields, C Koczor, R Russ, T Ludaway,
K Jackson, Q Qin, and W Lewis
Emory Univ, Atlanta, GA, US
Program 49
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