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Pocket Program - CROI

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Poster Listings<br />

Session 70 <strong>CROI</strong> 2013<br />

305 <br />

Avidity of HIV-1-specific CD8 T Cell Responses through<br />

<br />

Selena Vigano* 1 , F Bellutti-Enders1 , A-L Savoye1 , V Rozot1 ,<br />

C Cellerai1 , M Cavassini1 , S Ding2 , P-A Bart1 , G Pantaleo1,3 , and A Harari1,3 1 2 Lausanne Univ Hosp, Switzerland;; eurovacc, Amsterdam, The<br />

Netherlands;; and 3Swiss Vaccine Res Inst, Lausanne<br />

306 <br />

Markers of HIV Disease Progression and Attenuates<br />

Anti-HIV T Cell Responses in vitro<br />

Basile Siewe* 1 , J Stapleton2 , J Martinson1 , A Kesharvazian1 ,<br />

I Pandrea3 , A French1,4 , P Demarais4 , and A Landay1 1 2 Rush Univ Med Ctr, Chicago, IL, US;; Univ of Iowa and Iowa City<br />

VAMC, US;; 3Ctr for Vaccine Res, Univ of Pittsburgh, PA, US;; and 4CORE Ctr, Stroger Hosp of Cook County, Chicago, IL, US<br />

307 <br />

Mutations within HLA-B*5701-restricted Epitopes<br />

Marcus Buggert* 1 , M Norstrom1 , M Salemi2 , F Hecht3 , and A Karlsson1 1 2 Karolinska Inst, Stockholm, Sweden;; Univ of Florida, Gainesville, US;;<br />

and 3 317 <br />

in Virologically Suppressed ART-treated Patients<br />

Miriam Lichtner*, R Rossi, C Mascia, R Marocco, T Tieghi,<br />

F Mengoni, G Russo, P Zuccala, C Mastroianni, and V Vullo<br />

Sapienza Polo Pontino Univ of Rome, Italy<br />

318 Early Treatment Leads to a Better Profile of HIV<br />

<br />

S Hue<br />

Univ of California, San Francisco, US<br />

1 , Laurent Hocqueloux* 2 , M Surenaud1 , C Manier1 , J Guignard2 ,<br />

C Poillet1 , T Prazuck2 , C Lacabaratz1 , and Y Levy1 1 2 INSERM U955, Creteil, France and Ctr Hosp Regional d’Orleans, France<br />

319 The Long-term Persistence of Monoclonal Gammopathy<br />

in Patients on ART Is Associated with Epstein-Barr Virus<br />

Replication<br />

David Ouedraogo* 1,2,3 , A Makinson4 , J-P Vendrell1,2,3 , M-L Casanova4 ,<br />

A De Jong5 , N Nagot1 , J Reynes4 , P Van de Perre1,3 , and E Tuaillon1,2,3 1 2 INSERM U1058, Univ Montpellier 1, France;; Ctr Hosp Regional<br />

Univ de Montpellier, Inst de Recherche en Biotherapies, France;; 3Ctr Hosp Regional Univ de Montpellier, France;; 4Ctr Hosp Regional Univ<br />

de Montpellier, UMI 233, France;; and 5Univ de Montpellier, Hosp la<br />

Colombiere, France<br />

308 Immune Selection in a Pigtailed Macaque Model of SIV<br />

Central Nervous System Disease: Costs and Consequences<br />

Sarah Beck*, S Queen, and J Mankowski<br />

Johns Hopkins Univ Sch of Med, Baltimore, MD, US<br />

c Monday, 2:30-4 pm; Hall B2<br />

Session 71–Poster Abstracts<br />

Immune Restoration<br />

311 <br />

Successful HIV Suppression<br />

Emma Devitt* 1 , JM Rodriguez 1 , S Mandalia 1,2 , and A Pozniak 1<br />

1 Chelsea and Westminster Hosp, London, UK and 2 Imperial Coll London, UK<br />

+ 312 T Cells Is Associated with<br />

Impaired Immunological Recovery in HIV + Patients under<br />

HAART<br />

A Sennepin1,2,3 , F Baychelier1,3 , R Ho Tsong Fang2 , C Katlama4 , A Simon5 ,<br />

J Crouzet2 , V Vieillard1,3 , and Patrice Debre* 1,3<br />

1 2 INSERM UMRS 945, Paris, France;; Innavirvax SA, Evry, France;;<br />

3 4 Unive Pierre et Marie Curie, Paris-6, France;; Hosp Pitie-Salpetriere,<br />

Svc des Maladies Infectieuses, Paris, France;; and 5Hosp Pitie-Salpetriere,<br />

Svc de Med Interne, Paris, France<br />

315 Hyaluronic Acid as a Predictor of Immune Reconstitution<br />

following ART<br />

Ala Dababneh* 1 , N Cummins 1 , G Bren 1 , Z Temesgen 1 , D Bangsberg 2 ,<br />

and A Badley 1<br />

1 Mayo Clin, Rochester, MN, US and 2 Massachusetts Gen Hosp, Harvard<br />

Med Sch, Boston, US<br />

316 The Effect of HAART-induced HIV Viral Suppression on<br />

Markers of Immune Activation in the Multicenter AIDS<br />

Cohort Study<br />

Nikolas Wada* 1 , L Jacobson 1 , J Margolick 1 , E Breen 2 , and J Bream 1<br />

1 Johns Hopkins Univ Bloomberg Sch of Publ Hlth, Baltimore, MD, US<br />

and 2 Univ of California, Los Angeles, US<br />

30 20th Conference on Retroviruses and Opportunistic Infections<br />

c Wednesday, 2:30-4 pm; Hall B2<br />

Session 72–Poster Abstracts<br />

Microbial Translocation<br />

320 <br />

Diminished in Chronic Untreated HIV Infection<br />

Bjorn Corleis*, W Gostic, and D Kwon<br />

Ragon Inst of MGH, MIT, and Harvard, Boston, MA, US<br />

309 Phenotypic CD8 + T Cell Defects in Treated HIV Infection Are<br />

<br />

<br />

Sulggi Lee* 1 , E Sinclair1 , Y Huang1 , M Van Natta2 , D Bangsberg3 ,<br />

M Lederman4 , F Hecht1 , J Martin1 , S Deeks1 , and P Hunt1 1 2 Univ of California, San Francisco, US;; Johns Hopkins Univ, Baltimore,<br />

MD, US;; 3Massachusetts Gen Hosp and Harvard Univ, Boston, US;; and<br />

4Case Western Reserve Univ, Cleveland, OH, US<br />

310 <br />

Independent of the cART Regimen and Is Not Correlated<br />

<br />

Norma Rallon* 1 , B Torres2 , A Diaz2 , L Alos2 , E Martinez2 , A Leon2 ,<br />

J Gatell2 , V Soriano1 , F Garcia2 , and JM Benito1 321 Tight Junction mRNA Expression Decreases with a Proximal<br />

<br />

<br />

Charlotte Chung* and A Levine<br />

Case Western Reserve Univ Sch of Med, Cleveland, OH, US<br />

322 AIDS Virus Associated Gut Epithelial Barrier Dysfunction Is<br />

<br />

Christopher Gaulke*<br />

1 2 Hosp Carlos III, Madrid, Spain and Hosp Clin, Univ of Barcelona, Spain<br />

1 , I Grishina1 , M George1 , J Fass1 , N Joshi1 ,<br />

J Jovel2 , S-W Ding2 , D Lin1 , and S Dandekar1 1 2 Univ of California, Davis, US and Univ of California, Riverside, US<br />

323 <br />

<br />

Phenotype<br />

Amanda Steele*, E Lee, Z Dong, B Vestal, J Koeppe, and C Wilson<br />

Univ of Colorado Anchutz Med Campus, Aurora, US<br />

324 Immune Activation and T Cell Cycling Are Increased in<br />

Treated HIV Infection and Inflammatory Bowel Disease;;<br />

<br />

Nicholas Funderburg*, S Stubblefield-Park, H Sung, G Hardy,<br />

B Clagett, J Ignatz-Hoover, C Harding, J Katz, M Lederman, and A Levine<br />

Case Western Reserve Univ, Cleveland, OH, US<br />

313 <br />

Occurred Early and Was Greater in Those with More<br />

Advanced HIV-associated Immunodeficiency<br />

Denise Hsu* 1,2 , S Kerr1,2 , T Iampornsin2 , S Pett1 , A Avihingsanon2 ,<br />

P Thongpaeng2 , S Ubolyam2 , J Ananworanich2 , A Kelleher1 , and D Cooper1 1The Kirby Inst for Infection and Immunity in Society, Univ of New South<br />

Wales, Sydney, Australia and 2HIVNAT Res Collaboration, Thai Red<br />

Cross AIDS Res Ctr, Bangkok<br />

314 <br />

HIV + <br />

Correlates<br />

Ranjini Valiathan* 1 , D Gracia2 , and D Asthana1 325 Gut Lactobacillales during HIV Infection Are Associated with<br />

<br />

Josue Perez-Santiago*<br />

1 2 Univ of Miami Miller Sch of Med, FL, US and Borinquen Hlth Care Ctr,<br />

Miami, FL, US<br />

1 , S Gianella1 , M Massanella1 , M Karris1 ,<br />

S Var1 , D Patel1 , P Jordan1 , S Little1 , D Richman1,2 , and D Smith1,2 1 2 Univ of California, San Diego, La Jolla, US and VA San Diego Hlthcare<br />

System, CA, US<br />

326 <br />

and Mucosal Immunity after Oral Serum-derived Bovine<br />

<br />

David Asmuth* 1,2 , J Stombaugh3 , Z-M Ma4,5 , A Albanese1 , E Hodzic4 ,<br />

P Troia-Cancio2 , N Flynn2 , T Yotter2 , C Miller4,5 , and R Knight3 1 2 VA Northern California Hosp, Mather, US;; Univ of California, Davis<br />

Med Ctr, Sacramento, US;; 3Univ of Colorado, Boulder, US;; 4Univ of<br />

California, Davis, US;; and 5Ctr for Comparative Med, Davis, CA, US<br />

327 <br />

Untreated HIV-1 Infection and Correlate with T Cell<br />

<br />

Stephanie Dillon* 1 , E Lee1 , G Austin1 , Z Dong1 , K Rufner1 ,<br />

S Gianella Weibel2 , D Smith2 , and C Wilson1 1 2 Univ of Colorado Anschutz Med Campus, Aurora, US and Univ of<br />

California, San Diego, US<br />

328 <br />

Bacteria Is Increased in HIV-1 Infection and Is Associated<br />

<br />

Jennifer Manuzak*, S Dillon, E Lee, and C Wilson<br />

Univ of Colorado Anschutz Med Campus, Aurora, US

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