Pocket Program - CROI

Pocket Program - CROI Pocket Program - CROI

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Wednesday March 6 Oral Sessions Session 49 CROI 2013 C Wednesday, 2:30-4 pm; Hall B2 Poster Abstracts (see full session listings starting on page 24) Session 54. ART, Complications, and TB Session 57. Accessory Proteins/Gag Session 61. Macrophage HIV Interactions: Cell Biology and Treatment Session 65. HIV Genotypes and Phenotypes Session 68. HIV and Monocytes, Macrophages, and Dendritic Cells Session 72. Microbial Translocation Session 76. Neutralizing Antibodies and How to Stimulate Them Session 81. Mechanism of HIV Latency and Reactivation Session 83. Gene and Adoptive Immunotherapy Session 91. NeuroAIDS Clinical Studies Session 92. Neuroimaging Studies Session 93. Human Genomics Session 103. Compartment Penetration of ARV Session 104. ARV Drug Interactions Session 107. ART: Too Early or Too Late? Or Better Late than Never! Session 108. ART: Host and Viral Determinants of Outcome Session 109. ART: Care and Adherence Session 125. Hepatitis C Virus Epidemiology and Clinical Outcomes Session 129. HIV-associated Malignancies: Lymphoma Session 136. Microbial Translocation Measurement and Associations Session 139. ART Effects: Gene Expression and Cellular Function Session 140. Frailty: From Mice to Men and Women Session 142. Renal Disease: Diagnosis, Predictors, and Drugs Session 145. TB: Incidence, Risk Factors, and Outcomes Session 146. TB Diagnostics Session 148. The “ART” of TB Treatment Session 158. HIV Risk Factors, Prevalence, and Barriers to Care Session 159. Family Planning: Unintended Pregnancy and Unmet Need Session 160. HIV in Peri- and Post-menopause Session 165. Pregnancy Complications among HIV + Women Session 166. PMTCT: Maternal and Child Health Outcomes Session 177. HIV and ART-related Complications and Treatment in Children and Youth Session 179. Tenofovir in Children Session 181. Immune Response to Perinatal HIV Session 182. Response to Pediatric Vaccines in Children and Youth Session 185. Oral PrEP and ARV Adherence Session 189. MSM in the Developing World Session 192. Disease Progression, Morbidity, and Mortality Session 195. Biological and Behavioral Transmission Risks Session 196. Reducing Risk Session 199. Virologic Failure, 2 nd - and 3 rd -line Therapy in RLS 22 20th Conference on Retroviruses and Opportunistic Infections e Wednesday, 4-6 pm; B406 Session 50–Symposium Progress in Deciphering HIV Protective Immunity, a symposium in memory of Norman Letvin Conveners: Beatrice Hahn, Univ of Pennsylvania, Philadelphia, US Gary Nabel, Sanofi, Cambridge, MA, US 158 Viral Escape and Neutralizing Antibody Evolution in Early HIV-1 Infection Cynthia Derdeyn Emory Univ, Atlanta, GA, US 159 The Promise and Challenge of Broad and Potent Neutralizing Antibody Responses to HIV-1 Mark Connors HIV-Specific Immunity Section, NIAID, NIH, Bethesda, MD, US 160 The Role of CD4 T in Developing Durable Antibody Responses and as HIV Vaccine Hendrik Streeck US Military HIV Res Prgm, Walter Reed Army Inst of Res, Henry M Jackson Fndn, Silver Spring, MD 161 Stringent Control and Eventual Clearance of Highly Pathogenic SIV by Effector Memory T Cells Louis Picker Vaccine and Gene Therapy Inst, Oregon Natl Primate Res Ctr, Oregon Hlth and Sci Univ, Beaverton, US Objectives: This session is directed to clinicians and scientists interested in basic immunology, the immunology of HIV infection, or HIV vaccine development. It is assumed that participants will have some knowledge of basic immunological concepts including the impact of HIV on the immune system. At the completion of the session, participants will be knowledgeable about how replicating vaccine vectors might provide protection against SIV, how different CD4 T cells populations may be active in fighting HIV infection, how broadly neutralizing antibodies develop in some HIV + subjects, and the characteristics and potential uses of newly discovered broadly neutralizing antibodies.

CROI 2013 Session 52 e Wednesday, 4-6 pm; Ballroom 3-4 Session 51—Symposium HIV Testing and Monitoring the Epidemic: New Tools for Patients and Populations Conveners: Tsehaynesh Messele, African Society for Lab Med, Addis Ababa, Ethiopia Trevor Peter, Clinton Hlth Access Initiative, Boston, MA, US 162 HIV Self-testing: Opportunities and Challenges Julie Myers New York City Dept of Hlth and Mental Hygiene and Columbia Univ Med Ctr, NY, US 163 When Diagnosis Gets up Close and Personal: Point-of-Care Assays for Immunological and Virological Monitoring of HIV Disease Ilesh Jani Inst Nacional de Saude, Maputo, Mozambique 164 Accurate Cross-sectional HIV Incidence Testing Oliver Laeyendecker* 1,2 , R Brookmeyer 3 , M Kulich 4 , T Quinn 1,2 , J Konikoff 3 , M Cousins 2 , D Donnell 5,6 , and S Eshleman 2 1 NIAID, NIH, Baltimore MD, US;; 2 Johns Hopkins Univ, Baltimore, MD, US;; 3 Univ of California, Los Angeles, US;; 4 Charles Univ Prague, Czech Republic;; 5 Fred Hutchinson Cancer Res Ctr, Seattle, WA, US;; and 6 Univ of Washington, Seattle, US 165 Viral Load Measures: Patients, Populations, and Interpretations Irene Hall CDC, Atlanta, GA, US Objectives: The session is directed to clinicians and scientists interested in new laboratory methods for diagnosing HIV infection and monitoring the impact of treatment on individuals and populations. It is assumed that participants are familiar with the basic methods used to diagnose HIV infection and monitor the response to treatment. At the completion of the session, participants will be knowledgeable about home testing for HIV, monitoring response to therapy in resource-limited settings, measuring HIV incidence in populations, and the effect of treatment on community viral load. e Wednesday, 4-6 pm; Ballroom 1-2 Session 52—Symposium TB on the Verge Conveners: Constance Benson, Univ of California, San Diego Antiviral Res Ctr, US Papa Salif Sow, Global Hlth Prgm, Bill & Melinda Gates Fndn, Seattle, WA, US 166 Strategies for Prevention of Active TB Gavin Churchyard Aurum Inst and Sch of Publ Hlth, Univ of the Witwatersrand, Johannesburg, South Africa 167 Impact of Rapid Diagnostic Testing— Changing the TB Diagnostic Landscape Catharina Boehme Fndn for Innovative New Diagnostics, Geneva, Switzerland 168 Treatment of TB in Women and Children Soumya Swaminathan Natl Inst for Res in TB, Chennai, India 169 Management of Drug-resistant TB Alexander Pym KwaZulu-Natal Res Inst for TB and HIV, Nelson R Mandela Sch of Med, Univ of KwaZulu-Natal, Durban, South Africa Objectives: This session is directed to clinicians and scientists interested in the pathogenesis, diagnosis, treatment, and prevention of TB. It is assumed that participants are familiar with basic aspects of the disease and the current tools available for management of the disease. At the completion of the session, participants will be knowledgeable about challenges and limitations in prevention of HIV-related TB, newer molecular diagnostic tools for detecting Mycobacterium tuberculosis and drug resistance, unique challenges in the diagnosis and treatment of TB in pregnant women and children, and new approaches for the treatment of multidrug resistant TB. Program 23 Wednesday March 6 Oral Sessions

Wednesday<br />

March 6 Oral Sessions<br />

Session 49 <strong>CROI</strong> 2013<br />

C Wednesday, 2:30-4 pm; Hall B2<br />

Poster Abstracts<br />

(see full session listings starting on page 24)<br />

Session 54. ART, Complications, and TB<br />

Session 57. Accessory Proteins/Gag<br />

Session 61. Macrophage HIV Interactions: Cell Biology and Treatment<br />

Session 65. HIV Genotypes and Phenotypes<br />

Session 68. HIV and Monocytes, Macrophages, and Dendritic Cells<br />

Session 72. Microbial Translocation<br />

Session 76. Neutralizing Antibodies and How to Stimulate Them<br />

Session 81. Mechanism of HIV Latency and Reactivation<br />

Session 83. Gene and Adoptive Immunotherapy<br />

Session 91. NeuroAIDS Clinical Studies<br />

Session 92. Neuroimaging Studies<br />

Session 93. Human Genomics<br />

Session 103. Compartment Penetration of ARV<br />

Session 104. ARV Drug Interactions<br />

Session 107. ART: Too Early or Too Late? Or Better Late than Never!<br />

Session 108. ART: Host and Viral Determinants of Outcome<br />

Session 109. ART: Care and Adherence<br />

Session 125. Hepatitis C Virus Epidemiology and Clinical Outcomes<br />

Session 129. HIV-associated Malignancies: Lymphoma<br />

Session 136. Microbial Translocation Measurement and Associations<br />

Session 139. ART Effects: Gene Expression and Cellular Function<br />

Session 140. Frailty: From Mice to Men and Women<br />

Session 142. Renal Disease: Diagnosis, Predictors, and Drugs<br />

Session 145. TB: Incidence, Risk Factors, and Outcomes<br />

Session 146. TB Diagnostics<br />

Session 148. The “ART” of TB Treatment<br />

Session 158. HIV Risk Factors, Prevalence, and Barriers to Care<br />

Session 159. Family Planning: Unintended Pregnancy and Unmet Need<br />

Session 160. HIV in Peri- and Post-menopause<br />

Session 165. Pregnancy Complications among HIV + Women<br />

Session 166. PMTCT: Maternal and Child Health Outcomes<br />

Session 177. HIV and ART-related Complications and Treatment in<br />

Children and Youth<br />

Session 179. Tenofovir in Children<br />

Session 181. Immune Response to Perinatal HIV<br />

Session 182. Response to Pediatric Vaccines in Children and Youth<br />

Session 185. Oral PrEP and ARV Adherence<br />

Session 189. MSM in the Developing World<br />

Session 192. Disease Progression, Morbidity, and Mortality<br />

Session 195. Biological and Behavioral Transmission Risks<br />

Session 196. Reducing Risk<br />

Session 199. Virologic Failure, 2 nd - and 3 rd -line Therapy in RLS<br />

22 20th Conference on Retroviruses and Opportunistic Infections<br />

e Wednesday, 4-6 pm; B406<br />

Session 50–Symposium<br />

Progress in Deciphering HIV Protective Immunity,<br />

a symposium in memory of Norman Letvin<br />

Conveners:<br />

Beatrice Hahn, Univ of Pennsylvania,<br />

Philadelphia, US<br />

Gary Nabel, Sanofi, Cambridge, MA, US<br />

158<br />

Viral Escape and Neutralizing Antibody<br />

Evolution in Early HIV-1 Infection<br />

Cynthia Derdeyn<br />

Emory Univ, Atlanta, GA, US<br />

159<br />

The Promise and Challenge of Broad and<br />

Potent Neutralizing Antibody Responses to<br />

HIV-1<br />

Mark Connors<br />

HIV-Specific Immunity Section, NIAID, NIH, Bethesda, MD, US<br />

160<br />

The Role of CD4 T in Developing Durable<br />

Antibody Responses and as HIV Vaccine<br />

Hendrik Streeck<br />

US Military HIV Res Prgm, Walter Reed Army Inst of Res, Henry<br />

M Jackson Fndn, Silver Spring, MD<br />

161<br />

Stringent Control and Eventual Clearance of<br />

Highly Pathogenic SIV by Effector Memory<br />

T Cells<br />

Louis Picker<br />

Vaccine and Gene Therapy Inst, Oregon Natl Primate Res Ctr,<br />

Oregon Hlth and Sci Univ, Beaverton, US<br />

Objectives: This session is directed to clinicians and scientists<br />

interested in basic immunology, the immunology of HIV infection,<br />

or HIV vaccine development. It is assumed that participants will<br />

have some knowledge of basic immunological concepts including<br />

the impact of HIV on the immune system. At the completion of the<br />

session, participants will be knowledgeable about how replicating<br />

vaccine vectors might provide protection against SIV, how different<br />

CD4 T cells populations may be active in fighting HIV infection,<br />

how broadly neutralizing antibodies develop in some HIV + subjects,<br />

and the characteristics and potential uses of newly discovered<br />

broadly neutralizing antibodies.

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