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Pocket Program - CROI

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<strong>CROI</strong> 2013 Session 34<br />

e Tuesday, 4-6 pm; B406<br />

Session 33–Symposium<br />

HIV Host–Cell Interactions<br />

Conveners:<br />

Chioma Okeoma, Univ of Iowa, Iowa<br />

City, US<br />

Paul Spearman, Emory Univ, Atlanta,<br />

GA, US<br />

107<br />

Interferon-inducible Siglec, CD169, Is the<br />

Mature Dendritic Cell Receptor Essential for<br />

HIV-1 Trans-infection<br />

W Blay Puryear 1 , H Akiyama 1 , S Geer 1 , N Ramirez 1 , X Yu 2 ,<br />

B Reinhard 2 , and Rahm Gummuluru* 1<br />

1 Boston Univ Sch of Med, MA, US and 2 Boston Univ, MA, US<br />

108<br />

TRIM5 Restriction, HIV-1 Uncoating,<br />

and Relationship to Reverse Transcription<br />

Felipe Diaz-Griffero<br />

Albert Einstein Coll of Med, Bronx, NY, US<br />

109<br />

SAMHD1 Restricts HIV-1 Infection in Resting<br />

CD4 + T Cells<br />

Oliver Keppler<br />

Inst of Med Virology, Natl Reference Ctr for Retroviruses,<br />

Univ of Frankfurt, Germany<br />

110<br />

The Antiviral Activities of Tetherin<br />

RP Galao, S Pickering, A Le Tortorec, T Kueck,<br />

and Stuart Neil*<br />

Kings Coll London Sch of Med, Guys Hosp, UK<br />

Objectives: This session is directed to clinicians and scientists<br />

interested in understanding the host cell factors that promote and<br />

restrict HIV-1 replication. It is assumed that participants are familiar<br />

with cell biology, the retroviral lifecycle, and the proteins encoded<br />

in the HIV genome. At the completion of the session, participants<br />

will be knowledgeable about how dendritic cells facilitate HIV<br />

infection through their expression of specific cell-surface proteins,<br />

how host restriction proteins interfere with specific steps during<br />

virus replication, and mechanisms by which the virus has evolved to<br />

escape from these restrictions.<br />

e Tuesday, 4-6 pm; Ballroom 3-4<br />

Session 34–Symposium<br />

Reproductive Hormones and HIV<br />

Conveners:<br />

Ward Cates, FHI360, Research Triangle<br />

Park, NC, US<br />

Nelly Mugo, Univ of Washington,<br />

Nairobi, Kenya<br />

111<br />

Effects of Hormonal Contraceptives that May<br />

Affect Susceptibility to HIV Acquisition in<br />

Women<br />

Christine Mauck<br />

CONRAD, Arlington, VA, US<br />

112<br />

Assessing the Impact of Hormonal<br />

Contraceptives on HIV Risk and<br />

Prevention in Animal Models<br />

Gerardo Garcia-Lerma<br />

CDC, Atlanta, GA, US<br />

113<br />

What Have the Epidemiological Studies<br />

Taught Us about Hormonal Contraceptives<br />

and HIV-related Risks?<br />

Chelsea Polis *1 and R Heffron 2<br />

1 USAID, Office of Population and Reproductive Hlth,<br />

Washington, DC and 2 Univ of Washington, Seattle, US<br />

114<br />

<strong>Program</strong>matic Implications: Balancing<br />

Maternal Mortality and HIV Risk<br />

Jennifer Smith* 1 , A Butler 1 , C Polis 2 , S Gregson 1 , D Stanton 2 ,<br />

and T Hallett 1<br />

1 Imperial Coll London, UK and 2 US Agency for Intl Devt,<br />

Washington, DC<br />

5:30-6 pm<br />

Panel Discussion<br />

Objectives: This session is directed to clinicians and scientists<br />

interested in womens health, family planning, and HIV prevention.<br />

This session will be of interest to scientists conducting clinical<br />

studies of HIV prevention and epidemiologists evaluating risk<br />

factors for HIV acquisition and transmission. It is assumed<br />

that participants are familiar with reproductive biology and<br />

the data linking HIV risk with contraceptive hormones. At the<br />

completion of the session, participants will be knowledgeable<br />

about the epidemiologic and biologic data supporting the impact<br />

of reproductive and contraceptive hormones on HIV risk. In<br />

addition, participants will appreciate the public health impact of<br />

effective contraceptives and will learn how modeling studies have<br />

demonstrated that modest increases in HIV risk among women<br />

on hormonal contraceptives are offset by decreases in maternal<br />

mortality associated with unwanted pregnancy.<br />

<strong>Program</strong> 15<br />

Tuesday<br />

March 5 Oral Sessions

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