PDF download - Alumni Online - Mount Allison University
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y Laura Dillman Ripley<br />
With Simpsons characters painted<br />
on the walls and Iron Maiden<br />
playing in the background,<br />
biochemistry and chemistry professor Dr.<br />
Steve Westcott’s lab is not your typical chemistry<br />
set up. The Canada Research Chair<br />
(CRC) in Boron Pharmaceutical Chemistry<br />
has been making headlines for his work,<br />
which could see huge implications in the<br />
health and environmental chemical sectors.<br />
And he is doing this all with <strong>Mount</strong> <strong>Allison</strong><br />
undergraduate students at his side, through<br />
his popular research group, The Wild Toads.<br />
“Working with students is the best part of<br />
my job,” says Westcott, who on top of his<br />
research commitments as a CRC also teaches<br />
a full course load. “Being able to involve<br />
them in these research projects is wonderful<br />
as it enhances their undergraduate education<br />
by helping to establish a safe, fun, and<br />
productive lab where they can experience<br />
chemical research firsthand.”<br />
And these experiences are paying off.<br />
During his 15 years at <strong>Mount</strong> <strong>Allison</strong>, close<br />
to 100 students have co-authored a research<br />
at everyday elements...<br />
that could one day lead to natural<br />
anti-cancer treatments and/or<br />
environmentally-friendly pesticides,<br />
‘‘Looking<br />
are both pretty exciting possibilities<br />
paper with Westcott before graduation and<br />
many have gone on to master’s and PhD<br />
programs around the world.<br />
One of Westcott’s current projects, which<br />
recently captured national media attention,<br />
looks at the benefits of capsaicin, the active<br />
ingredient in hot peppers. This compound<br />
has been found to be an anti-cancer, antibacterial,<br />
and anti-fungal agent all in one.<br />
“We know capsaicin is good stuff. When<br />
you look at societies that use hot peppers<br />
frequently, their rates of certain health<br />
conditions, such as heart disease, are much<br />
lower than those where they are not as<br />
prevalent. We want to take a closer look<br />
at capsaicin, what makes it active, and see<br />
if we can create the derivative of this that<br />
could, one day, be made into a drug.”<br />
Capsaicin is found mainly in hot pepper<br />
seeds and the coating surrounding them.<br />
Westcott and his team, including several<br />
<strong>Mount</strong> <strong>Allison</strong> students as well as researchers<br />
from l’Université Laval and the Atlantic<br />
Cancer Research Institute, are working to<br />
separate the different compounds in the<br />
peppers to get a better idea of their chemical<br />
composition.<br />
’’<br />
The active ingredient in garlic is sulfur based.<br />
Westcott has also received funding to<br />
embark on new research looking at the<br />
health and environmental benefits of the<br />
elements boron (found in Borax) and sulfur,<br />
that many of us are familiar with for its smell.<br />
“Boron is an anti-cancer and anti-fungal<br />
agent and sulfur has a lot of bioactivities.<br />
We are working to make derivatives of<br />
these elements and see if we can combine<br />
the two to get something even better.”<br />
The idea of combining boron and sulfur<br />
derivatives is a novel one in the chemical<br />
world. not a lot of research has been completed<br />
in the area, making Westcott a pioneer<br />
in the field. Westcott, with the Wild Toads<br />
team, is enthusiastic about the new project.<br />
“Looking at everyday elements, like boron<br />
and sulfur, that could one day lead to natural<br />
anti-cancer treatments and/or environmentally-friendly<br />
pesticides, are both pretty<br />
exciting possibilities.”<br />
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