Detailed table of contents (pdf)

Table of Contents LV
17.5.2.2.1 Method 1: Photolysis Reaction of Azidopyridines with Nucleophiles .... 948
17.5.2.2.2 Method 2: Photochemical Conversion of N-Imides into 1,3-Diazepines .. 948
17.5.2.3 Synthesis by Substituent Modification ..................................... 949
17.5.2.3.1 Method 1: N,N¢-Diacylation of 6H-Dibenzo[d,f][1,3]diazepin-6-ones .... 949
17.5.2.3.2 Method 2: Displacement of Isothioureas .............................. 950
17.5.3 Product Subclass 3: 1,4-Diazepines ...................................... 951
17.5.3.1 Synthesis by Ring-Closure Reactions ....................................... 952
17.5.3.1.1 By Formation of Two N—C Bonds .......................................... 952
17.5.3.1.1.1 Method 1: Reaction of Benzene-1,2-diamines with 1,3-Diketones ....... 952
17.5.3.1.1.2 Method 2: Reaction of Benzene-1,2-diamines with 2-Halobenzoic Acids 954
17.5.3.1.1.3 Method 3: Reaction of Benzene-1,2-diamines with 2-Chloronicotinic
Acids ..................................................... 954
17.5.3.1.1.4 Method 4: Reaction of 2-Aminobenzoic Acids with 2-Halonitrobenzenes 956
17.5.3.1.1.5 Method 5: Reaction of 2-Aminobenzoic Acids with 2-Chloro-3pyridinamines
............................................ 957
17.5.3.1.2 By Formation of Two N—C Bonds and One C—C Bond ....................... 958
17.5.3.1.2.1 Method 1: Intramolecular Ring Closures Using Dimethylformamide
Dimethyl Acetal ........................................... 958
17.5.3.1.2.2 Method 2: Intramolecular Ring Closures through Imino Chlorides ...... 959
17.5.3.2 Synthesis by Ring Transformation .......................................... 960
17.5.3.2.1 Method 1: Intramolecular Nitrene Insertion Reactions of Azidopyridines 960
17.5.3.2.2 Method 2: Intramolecular Nitrene Insertion Reactions of Azidoquinolines 960
17.5.3.3 Synthesis by Substituent Modification ..................................... 962
17.5.3.3.1 By Replacement of Hydrogen ............................................. 962
17.5.3.3.1.1 Method 1: N-Acylation of 1,4-Diazepines .............................. 962
17.5.3.3.1.2 Method 2: C3Substitution of 1,5-Benzodiazepines by Direct Alkylation . 964
17.5.3.3.1.3 Method 3: C3 Substitution of 1,4-Benzodiazepines by Rearrangement .. 966
17.5.3.3.2 1,4-Diazepine Amidines from 1,4-Diazepinones ............................ 968
17.5.3.3.2.1 Method 1: Lewis Acid Mediated Formation from
Dihydro-1,4-diazepinones ................................. 968
17.5.3.3.2.2 Method 2: Imino Chloride Mediated Formation from
Dihydrodibenzo[1,4]diazepinones .......................... 969
17.5.3.3.2.3 Method 3: 1,5-Benzodiazepine Amidines from
Dihydro-1,5-benzodiazepine-2-thiones ..................... 970
17.5.3.3.2.4 Method 4: 1,4-Benzodiazepine Amidines from
Dihydro-1,4-benzodiazepine-2-thiones ..................... 972