02.03.2013 Views

Target Discovery and Validation Reviews and Protocols

Target Discovery and Validation Reviews and Protocols

Target Discovery and Validation Reviews and Protocols

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

Overview of Immune System 313<br />

measured by their ability to induce apoptosis in the target cell. Sc<strong>and</strong>. J. Immunol.<br />

41, 42–48.<br />

6. O’Neill, L. A. J. (2004) TLRs: Professor Mechnikov, sit on your hat. Trends<br />

Immunol. 25, 687–693.<br />

7. Janeway, C. A. (2001) How the immune system protects the host from infection.<br />

Microbes Infect. 3, 1167–1171.<br />

8. Janeway, C. A., Travers, P., Walport, M., <strong>and</strong> Shlomchik, M. (eds.) (2001)<br />

Immunobiology. The Immune System in Health <strong>and</strong> Disease. Garl<strong>and</strong> Publishing,<br />

New York.<br />

9. Matzinger, P. (1994) Tolerance, danger, <strong>and</strong> the extended family. Annu. Rev.<br />

Immunol. 12, 991–1045.<br />

10. Janeway, C. A. Jr. (1992) The immune system evolved to discriminate infectious<br />

nonself from noninfectious self. Immunol. Today 13, 11–16.<br />

11. Singer, A. (2002) New perspectives on a developmental dilemma: the kinetic signalling<br />

model <strong>and</strong> the importance of signal duration for the CD4/Cd8 lineage<br />

decision. Curr. Opin. Immunol. 14, 207–215.<br />

12. Orkin, S. H. (2000) Diversification of haematopoitic stem cells to specific lineages.<br />

Nat. Rev. Genet. 1, 57–64.<br />

13. Izon, D. J., Punt, A. J., <strong>and</strong> Pear, W. S. (2002) Deciphering the role of Notch signalling<br />

in lymphocytes. Curr. Opin. Immunol. 14, 192–199.<br />

14. Wilson, A., MacDonald, H. R., <strong>and</strong> Radtke, F. (2001) Notch 1-deficient common<br />

lymphoid precursors adopt a B cell fate in the thymus. J. Exp. Med. 194,<br />

1003–1012.<br />

15. Aifantis, I., Azogui, O., Feinberg, J., Saint-Ruf, C., Buer, J., <strong>and</strong> von Boehmer, H.<br />

(1998) On the role of the pre-T-cell receptor in αβ versus γδ T lineage commitment.<br />

Immunity 9, 649–655.<br />

16. Iritani, B. M., Alberola-Il, J., Forbush, K. A., <strong>and</strong> Perimutter, R. M. (1999)<br />

Distinct signals mediate maturation <strong>and</strong> allelic exclusion in lymphocytes progenitors.<br />

Immunity 10, 713–722.<br />

17. Muljo, S. A. <strong>and</strong> Schlissel, M. S. (2000) Pre-B <strong>and</strong> pre-T-cell receptors: conservation<br />

of strategies in regulating early lymphocyte development. Immunol. Rev.<br />

175, 80–93.<br />

18. Sleckman, B. <strong>and</strong> Khor, B. (2002) Allelic exclusion at the TCRb locus. Curr.<br />

Opin. Immunol. 14, 230–324.<br />

19. Myklebust, J. H., Smel<strong>and</strong>, S. M., Josefsen, D., <strong>and</strong> Sioud, M. (2000) Protein<br />

kinase C-alpha isoform is involved in erythropoietin-induced erythroid differentiation<br />

of CD34(+) progenitor cells from human bone marrow. Blood 95, 510–518.<br />

20. Padovan, E., Casorati, G., Dellabona, P., Meyer, S., Brockhaus, M., <strong>and</strong><br />

Lanzavecchia, A. (1993) Expression of two T cell receptor alpha chains: dual<br />

receptor T cells. Science 262, 422–424.<br />

21. Heath, W. R., Carbone, F. R., Bertolino, P., Kelly, J., Cose, S., <strong>and</strong> Miller, J. F.<br />

(1995) Expression of two T cell receptor alpha chains on the surface of normal<br />

murine T cells. Eur. J. Immunol. 25, 1617–1623.

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!