Target Discovery and Validation Reviews and Protocols

More documents

Recommendations

Info

Transfected Cell Arrays 161 5. Simpson, J. C., Wellenreuther, R., Poustka, A., Pepperkok, R., and Wiemann, S. (2000) Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. EMBO Rep. 1, 287–292. 6. Pepperkok, R., Girod, A., Simpson, J. C., and Rietdorf, J. (2000) Imunofluorescence microscopy, in Shepherd, P. and Dean, C., eds., Monoclonal Antibodies: A Practical Approach. Oxford University Press, New York, pp. 355–370.
Page 1 and 2:
METHODS IN MOLECULAR BIOLOGY 360 T
Page 3 and 4:
M E T H O D S I N M O L E C U L A R
Page 5 and 6:
© 2007 Humana Press Inc. 999 River
Page 7 and 8:
vi Preface get. Approaches to targe
Page 9 and 10:
viii Contents 10 Transgenic Animal
Page 11 and 12:
x Contributors SAHOHIME MATSUMOTO
Page 13 and 14:
xii Contents of Volume 2 12 Validat
Page 15 and 16:
2 Sioud disease pathogenesis and pe
Page 17 and 18:
4 Sioud A more fruitful approach fo
Page 19 and 20:
6 Sioud both transient and permanen
Page 21 and 22:
8 Sioud serum biomarkers. This syne
Page 23 and 24:
10 Sioud Fig. 2. Schematic of targe
Page 25 and 26:
12 Sioud 13. Magin, T. M. (1998) Le
Page 28 and 29:
Harnessing the Human Genome 15 The
Page 30 and 31:
Harnessing the Human Genome 17 Fig.
Page 32 and 33:
Page 34 and 35:
Page 36 and 37:
Harnessing the Human Genome 23 The
Page 38 and 39:
Page 40 and 41:
Harnessing the Human Genome 27 repr
Page 42 and 43:
Harnessing the Human Genome 29 14.
Page 44:
Harnessing the Human Genome 31 45.
Page 47 and 48:
34 Imoto et al. (4,5), and Bayesian
Page 49 and 50:
36 Imoto et al. 2. Materials Two ty
Page 51 and 52:
38 Imoto et al. Fig. 3. Graphical v
Page 53 and 54:
40 Imoto et al. Fig. 5. Result of t
Page 55 and 56:
42 Imoto et al. p(D |G) = ∫ p(D,
Page 57 and 58:
44 Imoto et al. β k (k = 1,…,q j
Page 59 and 60:
46 Imoto et al. Fig. 7. Partial res
Page 61 and 62:
48 Imoto et al. Fig. 8. Strategy to
Page 63 and 64:
50 Imoto et al. Fig. 9. (continued)
Page 65 and 66:
52 Imoto et al. Table 3 List of Roo
Page 67 and 68:
54 Imoto et al. 5. De Hoon, M. J. L
Page 69 and 70:
56 Imoto et al. 39. Kamimura, T., S
Page 71 and 72:
58 Beaty et al. cytotoxic drugs and
Page 73 and 74:
60 Beaty et al. Fig. 1. Principles
Page 75 and 76:
62 Beaty et al. oligonucleotide mic
Page 77 and 78:
64 Beaty et al. 3. The 12% polyacry
Page 79 and 80:
66 Beaty et al. 2.3.3. Protein Stai
Page 81 and 82:
68 Beaty et al. 3.1.3. Labeling of
Page 83 and 84:
70 Beaty et al. 1 µL of the anneal
Page 85 and 86:
72 Beaty et al. 4. Phenol:cholorfor
Page 87 and 88:
74 Beaty et al. 19. Wash twice with
Page 89 and 90:
76 Beaty et al. The Following Volum
Page 91 and 92:
78 Beaty et al. using a protein ass
Page 93 and 94:
80 Beaty et al. 6. Shake the gel fo
Page 95 and 96:
82 Beaty et al. Fig. 2. Preparation
Page 97 and 98:
84 Beaty et al. search in. A widely
Page 99 and 100:
86 Beaty et al. 3. Kern, S. E., Hru
Page 101 and 102:
88 Beaty et al. 34. Peters, D. G.,
Page 104 and 105:
5 Molecular Classification of Breas
Page 106 and 107:
Molecular Profiling of Breast Cance
Page 108 and 109:
Page 110 and 111:
Fig. 2. (Continued) the right ident
Page 112 and 113:
Page 114 and 115:
Page 116 and 117:
Page 118 and 119:
Page 120 and 121:
Page 122 and 123:
Page 124 and 125: Molecular Profiling of Breast Cance
Page 126 and 127: Molecular Profiling of Breast Cance
Page 128 and 129: 6 Discovery of Differentially Expre
Page 130 and 131: Gene Target Discovery 117 In the fi
Page 132 and 133: Gene Target Discovery 119 sequences
Page 134 and 135: Gene Target Discovery 121 There is
Page 136 and 137: Gene Target Discovery 123 digestion
Page 138 and 139: Gene Target Discovery 125 Fig. 1. P
Page 140 and 141: Gene Target Discovery 127 5. Sargen
Page 142: Gene Target Discovery 129 41. Berry
Page 145 and 146: 132 Matsumoto, Miyagishi, and Taira
Page 157 and 158: 144 Fig. 1. The ribozyme-expression
Page 159 and 160: 146 Sano and Taira 5. 10X L (low-sa
Page 161 and 162: 148 Sano and Taira ribozymes may cl
Page 163 and 164: 150 Fig. 3. A system for the identi
Page 165 and 166: 152 Sano and Taira 4. Notes 1. We r
Page 168 and 169: 9 Production of siRNA- and cDNA-Tra
Page 170 and 171: Transfected Cell Arrays 157 Fig. 1.
Page 172 and 173: Transfected Cell Arrays 159 2. The
Page 176 and 177: 10 Transgenic Animal Models in Biom
Page 178 and 179: Transgenic Models 165 giant mice ex
Page 180 and 181: Transgenic Models 167 2.1.3. Use of
Page 182 and 183: Transgenic Models 169 a recombinant
Page 184 and 185: Transgenic Models 171 Fig. 3. Diffe
Page 186 and 187: Transgenic Models 173 FRT sites are
Page 188 and 189: Transgenic Models 175 Fig. 4. Diffe
Page 190 and 191: Transgenic Models 177 models, the b
Page 192 and 193: Transgenic Models 179 Fig. 6. Vecto
Page 194 and 195: Transgenic Models 181 vectors can d
Page 196 and 197: Transgenic Models 183 then used to
Page 198 and 199: Transgenic Models 185 be fixed and
Page 200 and 201: Transgenic Models 187 period of inc
Page 202 and 203: Transgenic Models 189 (142). Genes
Page 204 and 205: Transgenic Models 191 from differen
Page 206 and 207: Transgenic Models 193 Acknowledgmen
Page 208 and 209: Transgenic Models 195 34. Thermes,
Page 210 and 211: Transgenic Models 197 68. Gupta, S.
Page 212 and 213: Transgenic Models 199 105. Weber, W
Page 214 and 215: Transgenic Models 201 138. Ranger,
Page 216 and 217: 11 Keratin Transgenic and Knockout
Page 218 and 219: Keratin Transgenics and Knockouts 2
Page 224 and 225:
211 K17 K17 Hair follicles, Alopeci
Page 226 and 227:
213 K6a K6a Hair follicles; Lysis o
Page 228 and 229:
Keratin Transgenics and Knockouts 2
Page 230 and 231:
Page 232 and 233:
Page 234 and 235:
Page 236 and 237:
Page 238 and 239:
Page 240 and 241:
Page 242 and 243:
Page 244 and 245:
Page 246 and 247:
Page 248 and 249:
Page 250 and 251:
Page 252 and 253:
Page 254 and 255:
Page 256 and 257:
Page 258 and 259:
Page 260 and 261:
Page 262 and 263:
Page 264:
Page 267:
254 Skovseth, Küchler, and Haralds
Page 270 and 271:
In Vivo Assay of Human Angiogenesis
Page 272 and 273:
Page 274 and 275:
Page 276 and 277:
Page 278 and 279:
Page 280 and 281:
Page 282 and 283:
13 A Murine Model for Studying Hema
Page 284 and 285:
Heart Failure and Immunity 271 We h
Page 286 and 287:
Heart Failure and Immunity 273 3.1.
Page 288:
Heart Failure and Immunity 275 6. W
Page 291 and 292:
278 Sioud gene products have been d
Page 293 and 294:
280 Sioud Fig. 1. Schematic of hema
Page 295 and 296:
282
Page 297 and 298:
284
Page 299 and 300:
286 Sioud selection), whereas thymo
Page 301 and 302:
288 Sioud Fig. 5. Affinity maturati
Page 303 and 304:
290 Sioud Fig. 6. A second signal i
Page 305 and 306:
292 Sioud Fig. 7. Bridging between
Page 307 and 308:
294 Sioud Fig. 8. Schematic of clas
Page 309 and 310:
296 Sioud Fig. 10. Critical molecul
Page 311 and 312:
298 Sioud In contrast to the expres
Page 313 and 314:
300 Sioud tumor infiltrating lympho
Page 315 and 316:
302 Sioud (see Chapter 15, Volume 1
Page 317 and 318:
304 Sioud display if the foreign pr
Page 319 and 320:
306 Sioud Fig. 13. Immunoscreening
Page 321 and 322:
308 Sioud molecular techniques have
Page 323 and 324:
310 Sioud Although much of the init
Page 325 and 326:
312 Sioud Because of their importan
Page 327 and 328:
314 Sioud 22. He, X., Janeway, C. A
Page 329 and 330:
316 Sioud 59. Sahin, U., Tureci, O.
Page 331 and 332:
318 Sioud 91. Golgher, D., Jones, E
Page 333 and 334:
320 Jäger Furthermore, this immune
Page 335 and 336:
322 Jäger Antigens that are tumor-
Page 337 and 338:
324 Jäger 2. Nakano, O., Sato, M.,
Page 339 and 340:
326 Jäger 31. Chen, Y. T., Gure, A
Page 341 and 342:
328 Le Naour dependent on CD8+ cyto
Page 343 and 344:
330 Le Naour Fig. 1. To illustrate
Page 345 and 346:
332 Le Naour heterogeneity of HCC,
Page 347 and 348:
334 Le Naour 15. Le Naour, F., Mise
Page 349 and 350:
336 Cekaite, Hovig, and Sioud Yeast
Page 351 and 352:
338 Cekaite, Hovig, and Sioud diffe
Page 353 and 354:
340
Page 355 and 356:
342 Cekaite, Hovig, and Sioud nonra
Page 357 and 358:
344 Cekaite, Hovig, and Sioud 3. Ue
Page 359 and 360:
346 Cekaite, Hovig, and Sioud 32. T
Page 361 and 362:
348 Cekaite, Hovig, and Sioud 65. L
Page 363 and 364:
350 Index Centroblast, 289 Centrocy
Page 365 and 366:
352 Index L Labeling mRNA, 62 Large
Page 367:
354 Index Tetraploid embryos, 239 g
show all

Target Discovery and Validation Reviews and Protocols

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?