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(INSA) Guidelines for Care and - Indian Council of Medical Research

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Annexure-8<br />

Commonly used Anaesthetic Drugs <strong>for</strong> Laboratory Animals<br />

Drugs Mouse Rat Hamster Guineapig Rabbit Cat Dog Monkey<br />

(mg/kg)<br />

Ketamine Hcl 22-24i/m 22-24i/m - 22-24 22-24 30i/m 30/im 15-40<br />

Pentobarbitone 35i/v 25i/v 35i/p 30-i/v 30i/v 25i/v 20-30i/v 35i/v<br />

Sodium 50i/p 50i/p 40i/p 40i/v<br />

Thiopentone 25i/v 20i/v 20i/v 20i/v 20i/v 25i/v 25i/v 25i/v<br />

50i/p 40i/p 40/p 55i/p 60i/p<br />

Urethane - 0.75i/p - 1.5i/p 1.0i/p,i/v 1.25i/v 1.00i/v 1.0i/v<br />

1.50i/p<br />

Atropine : Dose 0.02-0.05mg/kg <strong>for</strong> all species by s/c or i/m or i/v routes used to reduce salivary <strong>and</strong> bronchial secretions <strong>and</strong><br />

protect heart from vagal inhibition, given prior to anaesthesia<br />

I/m= intramuscular, i/v = intravenous, i/p = intraperitoneal, s/c = subcutaneous<br />

Source : Bibliography : Ref.Nos.3,14,27,30

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