d(GC) - Association of Biotechnology and Pharmacy
d(GC) - Association of Biotechnology and Pharmacy
d(GC) - Association of Biotechnology and Pharmacy
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Current Trends in <strong>Biotechnology</strong> <strong>and</strong> <strong>Pharmacy</strong><br />
Vol. 6 (2) 222-228 April 2012, ISSN 0973-8916 (Print), 2230-7303 (Online)<br />
the disease (15, 16, 18, 19), few studies have<br />
already reported that addition <strong>of</strong> NA with HA<br />
improving the vaccine efficiency (17, 20). Hence,<br />
a detailed study on the combination <strong>of</strong> these two<br />
antigens as a vaccine c<strong>and</strong>idate is a necessity.<br />
These rHA <strong>and</strong> rNA can also be used in the<br />
diagnosis <strong>of</strong> avian influenza as there are 16 HA<br />
subtypes <strong>and</strong> 9 NA subtypes have already been<br />
reported <strong>and</strong> for each type the HA <strong>and</strong> NA<br />
antigens can be readily expressed <strong>and</strong> purified<br />
in E.coli with in a very short duration. In addition<br />
to the possibility <strong>of</strong> using as subunit vaccines<br />
these antigens expressed in E.coli also pave a<br />
way for the development <strong>of</strong> easier <strong>and</strong> quicker<br />
diagnostic tools for avian influenza.<br />
Acknowledgement<br />
This study was supported by a funding<br />
from Council <strong>of</strong> Scientific <strong>and</strong> Industrial Research<br />
(CSIR), New Delhi, India.<br />
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