d(GC) - Association of Biotechnology and Pharmacy
d(GC) - Association of Biotechnology and Pharmacy
d(GC) - Association of Biotechnology and Pharmacy
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Current Trends in <strong>Biotechnology</strong> <strong>and</strong> <strong>Pharmacy</strong><br />
Vol. 6 (2) 210-221 April 2012, ISSN 0973-8916 (Print), 2230-7303 (Online)<br />
Table 1: Ethnopharmacological Importance <strong>of</strong> Asparagus recemosus (Willd.)<br />
S.No. Therapeutic use Proposed mechanism References<br />
<strong>of</strong> Asparagus racemosus<strong>of</strong> action<br />
1. Aphrodisiac Plant compound structurally <strong>and</strong>/or<br />
functionally similar to ovarian <strong>and</strong><br />
placental oestrogens. 10,8,9<br />
2. Alzheimer’s disease Antioxidative mechanism·<br />
Regulate neurotransmitters ·<br />
Neuritis regeneration 13<br />
3. Galactogague Activate adenohypophysis (anterior<br />
pituitary gl<strong>and</strong>) to produce prolactin 13,68,17<br />
4. Immunoadjuvant <strong>and</strong> Modify the antigenicity <strong>of</strong> immunization<br />
immunomodulater components.·<br />
activity Activate T cells·<br />
Up-regulation <strong>of</strong> Th1 (IL-2, IFN-g) <strong>and</strong><br />
Th2 (IL-4) cytokines. 18,19,24,70<br />
5. Antitussive activiy Anti-inflammatory property 20,21<br />
6. Adaptogenic activity Modulate stress mediators (corticosteroids,<br />
catecholamines, <strong>and</strong> nitric oxide) 69,25<br />
7. Anti-diarrhea activity Balancing the way fluid moves through intestines·<br />
Anti bacterial <strong>and</strong> anti viral activity·<br />
Reduce inflammation 79<br />
8. Antiulceric activity Inhibit lipid peroxidation <strong>and</strong> protein<br />
oxidation.Antioxidant activity 2,21,35,71,23,34<br />
9. Anti depressant Serotonin reuptake inhibitors· Antioxident<br />
activity Increase GABA level in the brain 24,38,69<br />
10. Anticancer activity Immunomodulater activity·<br />
Enhance production <strong>of</strong> inflammatory 69,72,41,46,44,73<br />
cytokines interleukin (IL)-1 <strong>and</strong> tumor<br />
necrosis factor (TNF)-alpha by macrophages·<br />
Inhibited the growth <strong>of</strong> human leukemia<br />
HL-60 cells<br />
11. Antilithiatic effect Asparagus racemosus ethanolic extract<br />
reduce oxalate, calcium <strong>and</strong> phosphate<br />
ions in urin which are the main cause <strong>of</strong><br />
renal stone formation. 34,48,49,50<br />
12. Antiparasitic activity Inhibition <strong>of</strong> parasite through antiparasitic<br />
agents which break parasite resistance system.<br />
Biochemical <strong>of</strong> this plant act by two ways:·<br />
Destruction <strong>of</strong> metabolic pathways <strong>of</strong> parasite.<br />
Disturb physical resistance system <strong>of</strong> parasite. 21,35,50,57,61<br />
13. Antidiebetic activity Hypoglycaemic activityIncreased<br />
intracellular Ca (2+) 65,74,75,76<br />
Manorma Sharma et al<br />
215