01.03.2013 Views

semmelweis university - Faculty of Physical Education and Sport ...

semmelweis university - Faculty of Physical Education and Sport ...

semmelweis university - Faculty of Physical Education and Sport ...

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

Aghabegloo, Mahmoud<br />

Islamic Azad University, Islamshahr Branch<br />

The Effects <strong>of</strong> Creatine Supplementation on Lactate, Nitrate <strong>and</strong> Nitrite<br />

Creatine supplementation has been shown to alleviate endothelial dysfunction <strong>and</strong> improve<br />

exercise performance through increasing nitric oxide production in patients with<br />

cardiopulmonary diseases. In addition, creatine supplementation could decrease<br />

accumulations <strong>of</strong> lactate <strong>and</strong> ammonia, metabolites involved in development <strong>of</strong> muscular<br />

fatigue. The aim <strong>of</strong> this study was to investigate the effect <strong>of</strong> shortterm creatine<br />

supplementation on performance in intermittent anaerobic exercise <strong>and</strong> the underlying<br />

mechanism in well-trained male athletes. Ten elite male college wrestlling athletes<br />

participated with a r<strong>and</strong>omized crossover, placebo-controlled design. The subjects consumed<br />

20 g/day creatine (CRE trial) or placebo (CON trial) for 5 days then performed an intermittent<br />

anaerobic exercise test on a treadmill. Blood samples were collected before supplementation,<br />

before <strong>and</strong> during exercise <strong>and</strong> 10 <strong>and</strong> 30 min after exercise. CRE trial had significantly<br />

higher creatine concentrations than CON trial at the same time point before, during <strong>and</strong> after<br />

exercise.There was no significant difference between the 2 trials in plasma nitrate <strong>and</strong> nitrite,<br />

lactate <strong>and</strong> ammonia concentrations <strong>and</strong> peak <strong>and</strong> average power in the exercise.The results <strong>of</strong><br />

this study suggested that short-term creatine supplementation had no effect on production,<br />

lactate <strong>and</strong> ammonia metabolism <strong>and</strong> performance in intermittent anaerobic exercise in welltrained<br />

male athletes.<br />

47

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!