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CRITICAL CARE

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Central Sydney Health Service Royal Prince Alfred Hospital<br />

ARTERIAL OXYGENATION GOAL<br />

Goal: SpO2 = 88 to 95 % or PaO2 = 55 to 80 mm Hg if ABG available<br />

� Adjust the FiO2 and PEEP according to the combinations outlined below. This can be<br />

performed every 5-10 minutes.<br />

� Adjustment to oxygenation can be made on SpO2 alone. It is not necessary to do blood<br />

gases to change FiO2. Blood gases should be performed as indicated. However, if a PaO2<br />

is available adjustments are made based on it, rather than SpO2.<br />

Fi02<br />

Peep<br />

0.3<br />

5<br />

0.4<br />

5<br />

0.4<br />

8<br />

0.5<br />

8<br />

0.5<br />

10<br />

0.6<br />

10<br />

ARTERIAL pH and PaCO2 / EtCO2<br />

Goal: pH = 7.30 – 7.45<br />

0.7<br />

� Leave the respiratory rate at the current settings<br />

Acidosis management: pH 7.10 – 7.30<br />

� Increase the ventilator rate until pH > 7.30 or PaCO2 < 35<br />

� PaCO2 is related to minute ventilation (MV = Vt x f)<br />

� Increasing f increases MV and “blows off” CO2 increasing pH<br />

� Maximum set ventilator rate is 35 bpm<br />

Acidosis Management: pH < 7.10<br />

� Increase the set ventilator rate to 35 bpm<br />

10<br />

� If pH remains < 7.10, tidal volume may be increased in 1ml/kg IBW steps until pH > 7.10<br />

Inform the senior register or duty consultant of an increase in tidal volume above 8 ml/kg<br />

IBW<br />

Alkalosis Management<br />

� Decrease the ventilator rate if possible<br />

0.7<br />

12<br />

0.7<br />

14<br />

0.8<br />

14<br />

0.9<br />

14<br />

0.9<br />

16<br />

0.9<br />

18<br />

1.0<br />

20-<br />

24

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