Continuous Flow Synthesis - Selected Examples from ... - ThalesNano

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X-Flash & H-Cube – One-Pot - Two Steps Suzuki C-C Coupling Followed by Hydrogenation • Due to the presence of Pd ~ 17% (GC-MS) of dehlogenated side-product are observed • At the currently used conditions for the H-Cube (0.1 M solution) 12% of the Suzuki product are not being reduced – further optimization needed (going down with the concentration). • Isolated yield at the specified conditions after chromatography – 48%
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Continuous Flow Synthesis - Selected Examples from ... - ThalesNano

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