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<strong>Final</strong> <strong>Program</strong>me & Abstracts<br />

First Joint <strong>Scandinavian</strong> Conference<br />

in Cardiothoracic Surgery<br />

The 58 th Annual Meeting of the <strong>Scandinavian</strong> <strong>Association</strong> <strong>for</strong> <strong>Thoracic</strong> Surgery (<strong>SATS</strong>)<br />

The 29 th Annual Meeting of The <strong>Scandinavian</strong> Society of Extra Corporeal Technology (SCANSECT)<br />

The 2 nd Annual Meeting of The <strong>Scandinavian</strong> Associaton of <strong>Thoracic</strong> Nurses (SATNU)<br />

The annual meetings <strong>for</strong> The Swedish <strong>Association</strong> <strong>for</strong> Cardiothoracic Surgery and<br />

The Swedish <strong>Association</strong> <strong>for</strong> Cardiothoracic Anesthesiology and Intensive Care<br />

STOCKHOLM August 20-22 <strong>2009</strong><br />

www.sats<strong>2009</strong>.org


Organisation<br />

Organizing Committee Scientific Committees<br />

Dan Lindblom (chairman, surgeon)<br />

<strong>SATS</strong><br />

Jan Hultman (Conference president, anesthesiologist)<br />

Ulf Lockowandt (surgeon)<br />

Sten Samuelsson (anesthesiologist)<br />

Anders Albåge (surgeon)<br />

Jan van der Linden (anesthesiologist)<br />

Ulrik Sartipy (surgeon)<br />

SCANSECT<br />

Per Stensved (president of SCANSECT)<br />

Conny Rundby<br />

Pia Vanhanen<br />

SATNU<br />

Susann Edvinsson Larsson (president of SATNU, OR)<br />

Birgitta Martinsson (anest.)<br />

Jennie Sandberg (ICU)<br />

Sofia Lorentzi (ward)<br />

PHYSIOTHERAPISTS SESSION<br />

Ulrika Thunström<br />

<strong>SATS</strong><br />

Timo Savunen (Secretary general, surgeon)<br />

Anders Jeppsson (surgeon)<br />

Daniel Steinbrüchel (surgeon)<br />

Odd Geiran (surgeon)<br />

Jari Laurikka (surgeon)<br />

Tómas Guðbjartsson (surgeon)<br />

Jan van der Linden (anesthesiologist)<br />

Knut Kirkebøen (anesthesiologist)<br />

SCANSECT<br />

Anne Louise Bellaiche (chairperson)<br />

Micael Appelblad<br />

Vivian Høyland<br />

Líney Símonardóttir<br />

Peter Fast Nielsen<br />

SATNU<br />

Marita Ritmala-Castrén (chairperson)<br />

Gunilla Barr<br />

Liselotte Brahe<br />

Kari Hanne Gjeilo


Table of contents<br />

Awards. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 06<br />

<strong>Program</strong>me Overview . . . . . . . . . . . . . . . . . . . . . . . 07<br />

Scientific <strong>Program</strong>me . . . . . . . . . . . . . . . . . . . . . . . 11<br />

Invited Speakers . . . . . . . . . . . . . . . . . . . . . . . . . . . 18<br />

Registration and hotel accommodation ..........18<br />

Social <strong>Program</strong>me ..........................20<br />

General in<strong>for</strong>mation .........................22<br />

Transportation .............................23<br />

Visiting Stockholm ..........................24<br />

Kistamässan Overview . . . . . . . . . . . . . . . . . . . . . . 26<br />

Exhibition .................................28<br />

Sponsors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30<br />

Author's Index .............................31<br />

Abstracts .................................37<br />

Conference and Exhibition Secretariat<br />

MCI Stockholm Office<br />

P.O. Box 6911<br />

SE-102 39 Stockholm, Sweden<br />

Phone: + 46 8 5465 1500<br />

Fax: +46 8 5465 1599<br />

E-mail: confirmation-sweden@mci-group.com<br />

All correspondence to the Organizing Committee may be sent to the Conference secretariat <strong>for</strong> further distribution.<br />

STOCKHOLM, SWEDEN 3<br />

Stockholm Visitors Board - Olof Holdar


Dear Friends and Colleagues<br />

On behalf of <strong>SATS</strong>, it is a pleasure and privilege to welcome you to the annual <strong>SATS</strong>, SCANSECT<br />

and SATNU meeting in Stockholm, August 20-22.<br />

We are proud to present this event as the<br />

“First Joint <strong>Scandinavian</strong> Conference in Cardiothoracic Surgery”<br />

In modern cardiothoracic surgery the importance of the teamwork approach is evident. Accordingly,<br />

we have tried to make the programme interesting <strong>for</strong> all attendants regardless of field of expertise<br />

in cardiothoracic surgery and its clinical challenges. The national and international response to this<br />

approach has been good. This year we welcome an unusually large number of anesthesiologists<br />

to the meeting and the number of nurses has more than doubled since last year. In addition we<br />

welcome a group of physiotherapists with a special interest in cardiothoracic surgery. The large<br />

number of participants is probably also a result of this conference being a joint venture with<br />

the Swedish <strong>Association</strong>s <strong>for</strong> Cardiothoracic Surgery and Cardiothoracic Anaesthesiology and<br />

Intensive Care. Consequently we should have enough prerequisites <strong>for</strong> interesting discussions<br />

among delegates with different experiences and approaches to everyday clinical issues in the<br />

fascinating, complicated and developing field of cardiothoracic surgery.<br />

We have been very <strong>for</strong>tunate in attracting well-known international lecturers in all topics of the meeting.<br />

Just in mentioning the main topics I would like to express special thanks to Prof. Gerald Buckberg and<br />

Prof. Anelechi Anyanwu, who will take part in The Right Heart topic on Thursday. For the second main<br />

topic on Saturday Prof. Ottavio Alfieri and Francesco Maisano, will guide us through the evolving<br />

Transcatheter Techniques <strong>for</strong> Heart Valve Diseases.<br />

Apart from the scientific programme I hope you all will find the social programme attractive.<br />

Stockholm has a lot to offer and I think all of you will enjoy the city. With all the respect to our Italian<br />

colleagues, Stockholm is sometimes referred to as “The Venice of the North”. True or not, there is<br />

plenty of water in and around the city and it’s clean enough <strong>for</strong> a swim.<br />

The Organizing Committee at The Department of Cardiothoracic Surgery and Anaesthesiology,<br />

Karolinska University Hospital, has done a great job in making this event possible. In this I would<br />

like to thank all colleagues <strong>for</strong> their contributions. Many thanks to the MCI group here in Stockholm,<br />

a true professional Congress Organizer. Also special thanks to the generosity from sponsors of the<br />

conference.<br />

Once more, welcome to the "First Joint <strong>Scandinavian</strong> Conference in Cardiothoracic Surgery" in<br />

Stockholm, August 20-22, <strong>2009</strong><br />

Jan Hultman<br />

Conference President<br />

4 www.sats<strong>2009</strong>.org


Transcatheter<br />

Valve<br />

CardioVascular. Innovation through Collaboration.<br />

Ventor valve is not approved yet and still under clinical trial.<br />

UC201001044EE


Awards<br />

<strong>SATS</strong><br />

C.W.Lillehei Young Investigators Award<br />

Sponsored by St. Jude Medical, the prize of USD 5000 is given to the best young investigator abstract, according<br />

to a decision of the board of <strong>SATS</strong> scientific committee.<br />

The Karl Victor Hall Award<br />

Sponsored by Medtronic, the prize of USD 5000 is given to the best abstract. Candidates may be members or nonmembers<br />

of <strong>SATS</strong>, but the author should have Nordic nationality or residency in a Nordic country. The selection is<br />

made by the board of <strong>SATS</strong> scientific committee.<br />

SCANSECT<br />

Medtronic Best Perfusionist Paper Presentation Award<br />

This is the prize <strong>for</strong> the best perfusionist paper presentation. The award is of €1000 and is sponsored by Medtronic.<br />

Sorin Group Best First Time Perfusionist Presenter Award<br />

This prize is awarded the best presentation by a perfusionist who presents <strong>for</strong> the first time at an international<br />

meeting. The award is of €500 and is sponsored by the Sorin Group.<br />

SCANSECT Best Perfusion School Graduation Paper Presentation Award<br />

This prize is awarded a perfusionist <strong>for</strong> the best school graduation paper presentation. The award is of €500 and is<br />

sponsored by SCANSECT.<br />

Maquet Best Case Report Presentation Award<br />

This is the award <strong>for</strong> the best case-report presented by a perfusionist. The award is of €500 and is sponsored by<br />

Maquet Cardiopulmonary.<br />

Terumo Best Perfusion Poster Presentation Award<br />

This is awarded <strong>for</strong> the best poster presented by a perfusionist. The award is of €300 and is sponsored by Terumo.<br />

SATNU<br />

Mölnlycke Best Nursing Speaker/Poster Travel Award<br />

Given <strong>for</strong> the best speaker/poster presented by a nurse. The travel award is SEK 5000 and is sponsored by Mölnlycke.<br />

ADDITIONAL AWARDS<br />

In addition to these <strong>Scandinavian</strong> awards there are also some awards specific <strong>for</strong> the Swedish <strong>Association</strong>s of<br />

Cardiothoracic Surgery and Cardiothoracic Anesthesiology and Intensive Care.<br />

• Edwards Life-Sciences travelling grant on SEK 15000 <strong>for</strong> education in valve surgery<br />

• Octopus Limedic travelling grant on SEK 15000 <strong>for</strong> best presentation at the meeting<br />

• Orion Pharma´s award on SEK 15000 <strong>for</strong> the best anesthesiological presentation<br />

• “Cardiothoracic Anesthesiologist of the year” – an award on SEK 5000 from the Swedish <strong>Association</strong> <strong>for</strong><br />

Cardiothoracic Anesthesiology and Intensive Care<br />

6 www.sats<strong>2009</strong>.org


<strong>Program</strong>me overview<br />

Thursday, 20 August <strong>2009</strong><br />

SCANSECT SATNU Physiotherapists<br />

<strong>SATS</strong><br />

Opening ceremony and Welcome<br />

13:00-13:30<br />

Timo Savunen, Secretary General <strong>SATS</strong><br />

Jan Hultman, Conference President<br />

Per Stensved, President SCANSECT <strong>2009</strong><br />

Susann Edvinsson Larsson, President SATNU<strong>2009</strong><br />

Main topic 1: The Right heart<br />

Moderators: Ulf Lockowandt and Anders Jeppsson<br />

Speakers:<br />

Gerald Buckberg; The Right Ventricle; from Structure to Function<br />

Jan Hultman; Evaluation of Right Ventricular Function<br />

Lars Algotsson; Peri- and Post-operative Right Ventricular Failure<br />

Anelechi Anyanwu; Surgery <strong>for</strong> Functional Tricuspid Regurgitation<br />

13:30-15:30<br />

Pause; visit the exhibition!<br />

15:30-16:15<br />

Introduction of the <strong>2009</strong> Clarence Crafoord lecturer<br />

Lars Wiklund, Chairman of the Swedish <strong>Association</strong> <strong>for</strong> <strong>Thoracic</strong> Surgery<br />

<strong>2009</strong> Clarence Crafoord lecture<br />

Professor Gerald Buckberg, UCLA<br />

A Unifying Geometric Approach to Dilated Cardiomyopathy from Many Causes<br />

STOCKHOLM, SWEDEN 7<br />

16:15-16:30<br />

16:30-17:30<br />

Gala Dinner at Solliden, Skansen<br />

19:30<br />

Individual transportation


<strong>Program</strong>me overview<br />

Friday, 21 August <strong>2009</strong><br />

<strong>SATS</strong><br />

SCANSECT SATNU Physiotherapists<br />

08:30-13:00 08:30-10:00<br />

08:30-10:15 08:30-10:00 08:30-09:00<br />

Oral abstract session<br />

Symposium; Weaning from long- Oral abstract session Introduction<br />

Moderators: Eva Berglin and Jan van der Linden<br />

term assist devices Moderators: Moderators: Unni Kleppe Ulrika Thunström<br />

Six abstracts nominated <strong>for</strong> the C.W Lillehei and K.V.Hall awards Laila Hellgren-Johansson and Haukeland and Marita 09:00-09:45<br />

Peter Svenarud Speakers: Lars Ritmala-Castren<br />

National guidelines <strong>for</strong><br />

Lund, Asghar Khaghani , Conny 10:00-10:30<br />

chest physiotherapy<br />

Rundby, Maria Eriksson<br />

Invited lecture<br />

Charlotte Urell<br />

Waiting <strong>for</strong> heart surgery 9:45-10:30<br />

Bodil Ivarsson<br />

Current practice <strong>for</strong><br />

Introduced by Gunilla Barr chest physiotherapy<br />

Elisabeth Westerdahl<br />

Pause 10:00-10:20<br />

Pause 10:15-10:45<br />

Pause 10:30-11:00 Pause 10:30-11:00<br />

10:20-11:30 10:45-13:00 11:00-13:00 11.00-11.30<br />

Oral abstract session (Cardiac)<br />

Oral abstract session<br />

Oral abstract session Smärta, lungfunktion<br />

Moderators: Odd Geiran and Åsa Haraldsson<br />

Moderators: Per Stensved and Moderators: Anita Tracey och opiater<br />

Else Nygren<br />

and Lotte Brahe<br />

Maria Antonsson<br />

Introduced by Sofia<br />

Pause 11:30-11:50<br />

Broman<br />

11:50-13:00 11:50-13:00<br />

Oral abstract session<br />

Oral abstract session (Basic<br />

(Cardiothoracic) Moderators: science) Moderators: Gabriella<br />

Tómas Guðbjartsson and Kristiina Lindvall and Ulrik Sartipy<br />

Hersio<br />

8 www.sats<strong>2009</strong>.org<br />

13:00-14:15<br />

Lunch, visit the exhibition!<br />

Symposium; Humanitarian Work in Cardiac Surgery<br />

Moderators: Dan Lindblom and Eva Ahlgren<br />

Speakers:<br />

Stefan Peterson; Impact of Cardiovascular Diseases in Developing Countries<br />

Sylvain Chauvaud; Experiences by Chaine de l´espoir<br />

Gino Strada; Experiences by Emergency<br />

Coffee; visit the exhibition!<br />

14:15-15.45<br />

Exchange of<br />

experiences<br />

Moderators; Ulrika<br />

Thunström and Sofia<br />

Broman<br />

Invited lecture<br />

Psychosocial aspects of<br />

heart failure<br />

Anna Strömberg<br />

Introduced by Anita Tracey<br />

Invited Lecture;<br />

Long Term Assist Devices<br />

previous, current and <strong>for</strong>ecast<br />

Heinz-Hermann Weitkemper<br />

Introduced by Anne-Louise<br />

Bellaiche<br />

15:45-16:15<br />

16:15-17:15 Invited Lecture<br />

Critically Interpreting the<br />

mitral literature<br />

Anelechi Anyanwu<br />

Introduced by Sten Samuelsson<br />

Awards and pre-dinner party<br />

17:30-18:45<br />

Buses leave from Kista-mässan<br />

Buffet dinner at the Stockholm City Hall<br />

Steamboat tour in the Stockholm Archipelago<br />

18:45<br />

19:30<br />

21:15


Saturday, 22 August <strong>2009</strong><br />

<strong>SATS</strong><br />

SCANSECT SATNU Physiotherapists<br />

08:30-10:00 Cardiogenic shock in myocardial Infarction<br />

Invited lecture Oral abstract<br />

Moderators; Anders Albåge and Jan Hultman<br />

Reducing VAP session<br />

Speakers:<br />

in the ICU Moderator;<br />

Lars Lund; Background and Current Guidelines <strong>for</strong> Intervention<br />

Eva Joelsson Alm Gun Faager<br />

Lars Wiklund; Revascularization and Other Surgical Options<br />

Introduced by Gunilla Barr<br />

Asghar Khaghani; Mechanical support<br />

General assembly<br />

10:00-10:30 General assembly<br />

General assembly<br />

09:30-10:30<br />

10:30-11:00<br />

Pause; vixit the exhibition!<br />

11:00-13:00<br />

Main topic 2; Transcatheter Valve Techniques<br />

Moderator: Anders Jönsson<br />

History and Future of Aortic Valve Implantation<br />

Speaker: Ottavio Alfieri<br />

Invited discussant: Kenneth Pehrsson<br />

History and Future of Mitral Valve Interventions<br />

Speaker: Francesco Maisano<br />

Invited discussant: Reidar Winter<br />

13:00-13:15<br />

Closing remarks<br />

Jan Hultman<br />

15:00-16:00 Visit at Karolinska. Contact<br />

Susann Edvinsson Larsson<br />

(susann.edvinssonlarsson@satnu.org)<br />

if you<br />

are interested<br />

STOCKHOLM, SWEDEN 9


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Physiologic<br />

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Freestyle, Mosaic, and Hancock are registered trademarks of Medtronic, Inc.<br />

1. Medtronic data on file.<br />

Implantability<br />

Mosaic® Valve<br />

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Hancock® II Valve<br />

UC<strong>2009</strong>02649 EE<br />

© Medtronic, Inc. <strong>2009</strong><br />

All Rights Reserved


Scientific <strong>Program</strong>me<br />

THURSDAY, 20 AUGUST <strong>2009</strong><br />

13:00 - 13:30 Opening Ceremony Lecture room M2<br />

Welcome<br />

Timo Savunen, Secretary General <strong>SATS</strong><br />

Jan Hultman, Conference President<br />

Per Stensved, President SCANCSECT <strong>2009</strong><br />

Susann Edvinsson Larsson, President SATNU <strong>2009</strong><br />

13:30 - 15:30 Main topic 1: The Right heart Lecture room M2<br />

Moderators: Ulf Lockowandt and Anders Jeppsson<br />

Speakers:<br />

Gerald Buckberg; The Right Ventricle; from Structure to Function<br />

Jan Hultman; Evaluation of Right Ventricular Function<br />

Lars Algotsson; Peri- and Post-operative Right Ventricular Failure<br />

Anelechi Anyanwu; Surgery <strong>for</strong> Functional Tricuspid Regurgitation<br />

15:30 - 16:15 Pause; visit the exhibition!<br />

16:15 - 16:30 Introduction of the <strong>2009</strong> Clarence Crafoord lecturer Lecture room M2<br />

Lars Wiklund, Chairman of the Swedish <strong>Association</strong> <strong>for</strong> <strong>Thoracic</strong> Surgery<br />

16:30 - 17:30 <strong>2009</strong> Clarence Crafoord lecture Lecture room M2<br />

Professor Gerald Buckberg, UCLA<br />

A Unifying Geometric Approach to Dilated Cardiomyopathy from Many Causes<br />

19:30 Gala Dinner at Solliden, Skansen<br />

Individual transportation.<br />

STOCKHOLM, SWEDEN 11<br />

www.exigus.se


FRIDAY, 21 AUGUST <strong>2009</strong><br />

08:30 - 10:00 S01 <strong>SATS</strong> Award nominees’ Oral abstract session Lecture room M1<br />

Moderators: Eva Berglin and Jan van der Linden<br />

Six abstracts nominated <strong>for</strong> the C.W Lillehei and K.V.Hall awards<br />

08:30 - 08:45 S01:1 Impact of Papillary Muscle Relocation as Adjunct Procedure to Mitral Ring Annuloplasty in<br />

Functional Ischemic Mitral Regurgitation<br />

Henrik Jensen, Morten Jensen, Morten Smerup, Per Wierup, Steffen Ringgaard,<br />

J. Michael Hasenkam, Sten Lyager Nielsen, Denmark<br />

08:45 - 09:00 S01:2 Aprotinin reduces the antiplatelet effect of clopidogrel.<br />

Gabriella Lindvall, Ulrik Sartipy, Staffan Bjessmo, Peter Svenarud, Bo Lindvall,<br />

Jan van der Linden, Sweden<br />

09:00 - 09:15 S01:3 30-day outcomes in high risk-patients randomized to off-pump or on-pump<br />

coronary bypass Surgery<br />

Christian H Møller, Mario Perko, Jens Lund, Lars W. Andersen, Jan K. Madsen,<br />

Christian Gluud, Daniel A. Steinbrüchel, Denmark<br />

09:15 - 09:30 S01:4 Catheter based aortic valve implantation – results from the first 50 patients<br />

Hans Henrik Møller Nielsen, Leif Thuesen, Henning Rud Andersen, Vibeke E Hjortdal,<br />

Kaj-Erik Klaaborg, Carl-Johan Jakobsen, Ingeborg Böing, Denmark<br />

09:30 - 09:45 S01:5 The New TNM Staging System <strong>for</strong> Lung Cancer - A Review of 511 patients operated at<br />

Karolinska University Hospital.<br />

Per Bergman, Daniel Brodin, Luigi De Petris, Sweden<br />

09:45 - 10:00 S01:6 Non-selective cyclooxygenase (COX) inhibition decreases shunt during one-lung<br />

ventilation <strong>for</strong> thoracic surgery.<br />

Danguole Rimeika, Sten GE Lindahl, Claes U Wiklund, Sweden<br />

08:30 - 10:15 S02 SCANSECT Symposium; Weaning from longterm assist devices Lecture room E5<br />

Moderators: Laila Hellgren-Johansson and Peter Svenarud<br />

Speakers:<br />

Lars Lund; Cardiological aspects<br />

Maria Eriksson; Evaluation of myocardial recovery by echocardiography<br />

Conny Rundby; The role of the perfusionist<br />

Asghar Khaghani; The Harefield experience<br />

08:30 - 10:00 S03 SATNU Oral abstract session Lecture room M2<br />

Theme: Dealing with patients' physical postoperative problems<br />

Moderators: Unni Kleppe Haukeland and Marita Ritmala-Castren<br />

08:30 - 08:45 S03:1 Postoperative nausea and vomiting after cardiac surgery: nursing point of view<br />

Timo Murkka, Anu Niemi, Kati Järvelä, Pasi Maaranen, Heini Huhtala, Tero Sisto, Finland<br />

08:45 - 09:00 S03:2 Prediction of the consumption of opioid analgesics following minimally invasive correction<br />

of pectus excavatum<br />

Kasper Grosen, Hans K. Pilegaard, Mogens P. Jensen, Denmark<br />

09:00 - 09:15 S03:3 Gabapentin <strong>for</strong> postoperative pain management after cardiac surgery with median sternotomy<br />

Vibeke Laursen, Mariann Tang, Imran Parvaiz, Vibeke Hjortdal, Denmark<br />

09:15 - 09:30 S03:4 The effect of soothing music in response to stress and relaxation during bed rest after open-<br />

heart surgery.<br />

Ulrica Nilsson, Sweden<br />

09:30 - 09:45 S03:5 Nursemanaged insulin protocol improves treatment of hyperglycaemia in patients with<br />

diabetes undergoing open heart surgery<br />

Aase Lange, Denmark<br />

09:45 - 10:00 S03:6 Prevalance of postoperative problems among Danish heart-operated patients 14 days after<br />

discharge from hospital<br />

Dorthe Ibsen, Helle Greve, Denmark<br />

10:00 - 10:30 S03:B SATNU Invited Lecture Lecture room M2<br />

Waiting <strong>for</strong> heart surgery<br />

Bodil Ivarsson introduced by Gunilla Barr<br />

12 www.sats<strong>2009</strong>.org


FRIDAY, 21 AUGUST <strong>2009</strong><br />

08:30 - 10:30 S04 Physiotherapists Lecture room M3<br />

08:30 - 09:00 Introduction<br />

Ulrika Thunström<br />

09:00 - 09:45 National guidelines <strong>for</strong> chest physiotherapy<br />

Charlotte Urell<br />

09:45 - 10:30 Current practice <strong>for</strong> chest physiotherapy<br />

Elisabeth Westerdahl<br />

Pause<br />

10:20 - 11:30 S05 <strong>SATS</strong> Cardiac Oral abstract session Lecture room M1<br />

Moderators: Odd Geiran and Åsa Haraldsson<br />

10:20 - 10:30 S05:1 Initial experience with a catheter based aortic valve implantation system.<br />

Henrik Ahn, Jacek Baranowski, Wolfgang Freter, Niels Erik Nielsen, Eva Nylander,<br />

Lars Wallby, Eva Tamas, Sweden<br />

10:30 - 10:40 S05:2 Echo-guided presentation of aortic valve minimises contrast medium exposure in Sapien<br />

aortic valve recipients.<br />

Jacek Baranowski, Henrik Ahn, Wolfgang Freter, Niels Erik Nielsen, Eva Nylander,<br />

Eva Tamas, Lars Wallby, Sweden<br />

10:40 - 10:50 S05:3 Survival and quality of life after aortic root replacement with cryopreserved homografts in<br />

acute endocarditis<br />

Sossio Perrotta, Obaid Aljassim, Odd Bech-Hanssen, Anders Jeppsson,<br />

Gunnar Svensson, Sweden<br />

10:50 - 11:00 S05:4 Mitral valve repair using Gore-tex neochordae, “respect rather than resect”.<br />

Susanne Juel Holme, John Christensen, Morten Kjøller, Thomas Fritz-Hansen, Denmark<br />

11:00 - 11:10 S05:5 Minimally invasive reoperative aortic valve surgery with patent coronary artery bypass grafts<br />

Giuseppe Raffa, Sudan, Carlo Pellegrini, Marcello Savasta, Matteo Pozzi, Mario Vigano, Italy<br />

11:10 - 11:20 S05:6 Hypothyroidism in cardiac surgery patients. A single unit follow-up.<br />

Aarne Jyrala, Gregory L Kay, United States<br />

11:20 - 11:30 S05:7 Continuous venovenous hemodialysis (CVVHD) with citrate calcium reduces<br />

postoperative bleeding complications after cardiac surgery<br />

Arndt-H. Kiessling, Michael Neher, Angela Kornberger, Andreas Lehmann, Bergner Raoul,<br />

Frank Isgro, Werner Saggau, Germany<br />

STOCKHOLM, SWEDEN 13<br />

www.exigus.se


FRIDAY, 21 AUGUST <strong>2009</strong><br />

10:45 - 13:00 S06 SCANSECT Oral abstract session Lecture room E5<br />

Moderators: Per Stensved and Else Nygreen<br />

10:45 - 11:00 S06:1 Fibrinogen and the acute inflammatory response after cardiac surgery<br />

Maria Kalabic, Anders Jeppsson, Helena Rexius, Sweden<br />

11:00 - 11:15 S06:2 Platelet aggregability be<strong>for</strong>e and after coronary artery bypass surgery<br />

Linda Önsten, Anders Jeppsson, Helena Rexius, Sweden<br />

11:15 - 11:30 S06:3 Will use of mini CPB lead to higher levels of haemoglobin, less use of blood products and<br />

improved fluid balance?<br />

Bente Övrebö, Hege Eikemo, Arve Mongstad, Finn Eliassen, Marit Farstad,<br />

Rune Haaverstad, Norway<br />

11:30 - 11:45 S06:4 In Vitro Comparison of the New In-line Monitor BMU 40 vs. the Conventional Laboratory<br />

Analyser ABL 700<br />

F. Oliver Grosse, Germany, David Holzhey, Volkmar Falk, Switzerland,<br />

Jan Schaarschmidt, Klaus Kraemer, Friedrich Wilhelm Mohr, Germany<br />

11:45 - 12:00 S06:5 Clinical Evaluation of the new BMU 40 In-Line Blood Analysis Monitor<br />

Jan Schaarschmidt, Michael Andrew Borger, Joerg Seeburger, Frank Oliver Grosse,<br />

Klaus Kraemer, Friedrich Wilhelm Mohr, Germany<br />

12:00 - 12:15 S06:6 ECMO - The Icelandic experience<br />

Thorsteinn Astradsson, Bjarni Torfason, Tomas Gudbjartsson, Liney Simonardottir,<br />

Felix Valsson, Iceland<br />

12:15 - 12:30 S06:7 Extracorporeal membrane oxygenation support <strong>for</strong> 59 days without changing the ecmo circuit<br />

Amrit Singh Thiara, Vivian Høyland, Hilde Norum, Tor Aasmundstad, Harald Karlsen,<br />

Arnt Fiane, Odd Geiran, Norway<br />

12:30 - 12:45 S06:8 Coagulation in oxygenator and arterial filter after recirculation<br />

Anne Louise Bellaiche, Peter Fast Nielsen, Pia Sprogøe, Oddvar Klungreseth, Denmark<br />

11:00 - 13:00 S07 SATNU Oral abstract session Lecture room M2<br />

Theme 11.00-11.45: Competence at work. Theme 11.45-13.00: Surviving heart disease<br />

Moderators: Anita Tracey and Lotte Brahe<br />

11:00 - 11:15 S07:1 How does nursing competence express itself in the operating room?<br />

Charlotte Walsoe, Denmark<br />

11:15 - 11:30 S07:2 The operating room nurses experiences of the medical equipment in their daily work<br />

Christine Roman-Emanuel, Doris Hägglund, Sweden<br />

11:30 - 11:45 S07:3 Surgical Team Member's Experiences, Routines and Views be<strong>for</strong>e Implementation of a<br />

Time-out protocol<br />

Shamini Murugesh, Arvid Haugen, Rune Haaverstad, Haldor Slettebø, Grethe Daavoy,<br />

Eirik Soefteland, Norway<br />

11:45 - 12:00 S07:4 Out of Hospital(OoH) management of patients on LVADs (Left ventricular assist devices).<br />

The Norwegian experience.<br />

Gro Sorensen, Einar Gude, Marianne Holter, Arnt Fiane, Norway<br />

12:00 - 12:15 S07:5 Gender and health-related quality of life after cardiac surgery<br />

Kari Hanne Gjeilo, Alexander Wahba, Pål Klepstad, Stian Lydersen, Roar Stenseth, Norway<br />

12:15 - 12:30 S07:6 Quality of life in patients and his relatives undergoing percutaneous pulmonary valve implant<br />

Brith Andresen, Gaute Døhlen, Lars Mathisen, Norway, Marit Andersen, Harald Lindberg,<br />

Erik Fosse, Norway<br />

12:30 - 12:45 S07:7 Addressing the Spouses Unique Needs after Cardiac Surgery when Recovery is<br />

Complicated by Heart Failure<br />

Susanna Ågren, Anna Strömberg, Rolf Svedjeholm, Sören Berg,<br />

Gunilla Hollman Frisman, Sweden<br />

12:45 - 13:00 S07:8 Patient education in a representative sample of patients having elective cardiac surgery in Iceland<br />

Heida Steinunn Olafsdottir, Brynja Ingadottir, Herdis Sveinsdottir, Iceland<br />

14 www.sats<strong>2009</strong>.org


FRIDAY, 21 AUGUST <strong>2009</strong><br />

11:00 - 11:30 S08 Physiotherapists Lecture room M3<br />

Smärta, lungfunktion och opiater<br />

Maria Antonsson introduced by Sofia Broman<br />

11:50 - 13:00 S09 <strong>SATS</strong> Cardiothoracic Oral abstract session Lecture room M1<br />

Moderators: Tómas Guðbjartsson and Kristiina Hersio<br />

11:50 - 12:00 S09:1 Outcome after pulmonary metastasectomy: Analysis of surgical resections during a 5 year period.<br />

Kåre Hornbech, Jesper B. Ravn, Daniel A. Steinbrüchel, Denmark<br />

12:00 - 12:10 S09:2 Surgical resection of pulmonary metastases from colorectal carcinoma in Iceland<br />

Halla Vidarsdottir, Pall Moller, Jon Gunnlaugur Jonasson, Tomas Gudbjartsson, Iceland<br />

12:10 - 12:20 S09:3 The No touch vein graft harvesting technique <strong>for</strong> CABG preserves a functional vasa vasorum<br />

Mats Dreifaldt, Domingos Souza, Sweden, Andrzej Loesch, John Muddle, United Kingdom,<br />

Mats Karlsson, Lars Norgren, Sweden, Michael Dashwood, United Kingdom<br />

12:20 - 12:30 S09:4 Is there a place <strong>for</strong> total endoscopic ablation of atrial fibrillation?<br />

Anders Ahlsson, Espen Fengsrud, Peter Linde, Hans Tyden, Anders Englund, Sweden<br />

12:30 - 12:40 S09:5 Sternal Closure with Thermoreactive clips in 1000 High risk patients<br />

- A Single Centre Cohort Study.<br />

Sendhil Kumaran Balasubramanian, Joel Dunning, Vassilios Avlonitis, Michael Gill,<br />

Andrew Goodwin, Andrew Owens, Simon Kendall, United Kingdom<br />

12:40 - 12:50 S09:6 Cardiac Surgery in Patients with Haemophilia<br />

Mariann Tang, Per Wierup, Kim Terp, Jørgen Ingerslev, Benny Sørensen, Denmark<br />

12:50 - 13:00 S09:7 Surgical correction of pectus excavatum and carinatum - six years of experiences at<br />

Karolinska University Hospital.<br />

Per Bergman, Sweden<br />

11:50 - 13:00 S10 <strong>SATS</strong> Basic Science Oral abstract session Lecture room E4<br />

Moderators: Gabriella Lindvall and Ulrik Sartipy<br />

11:50 - 12:00 S10:1 Injection of Mesenchymal Stem Cells Modified with VEGF Gene in Ischemic myocardium<br />

Improves Cardiac Function in Rats<br />

Ping Hua, China, Yanqi Yang, Sweden, Ju Chen, Jiangzhou Peng, Bosheng Chen,<br />

Jie Han, Youyu Wang, China<br />

12:00 - 12:10 S10:2 Effect of Down-Regulated Cyclophilin D on Protection of Endothelial Cells Against<br />

Oxidative Injury<br />

Jiangzhou Peng, China, Yanqi Yang, Sweden, Ping Hua, Ju Chen, Jie Han,<br />

Bosheng Chen, Lei Xue, China<br />

12:10 - 12:20 S10:3 Validation of cystatin C with iohexol clearance in cardiac surgery.<br />

Björn Brondén, Atli Eyjolfsson, Sten Blomquist, Henrik Jönsson, Sweden<br />

12:20 - 12:30 S10:4 Platelet reactivity during Cardiopulmonary bypass (CPB)<br />

- Changes related to postoperative bleeding<br />

Gustaf Ehnsiö, Joakim Norderfeldt, Sören Berg, Joakim Alfredsson, Sweden<br />

12:30 - 12:40 S10:5 The Human heart releases cardiotrophin-1after coronary artery bypass grafting with<br />

cardiopulmonary bypass<br />

Yikui Tian, Xinhua Ruan, China, Jari Laurikka, Seppo Laine, Matti Tarkka, Finland,<br />

Minxin Wei, China<br />

12:40 - 12:50 S10:6 Acute kidney injury following coronary artery bypass surgery using the RIFLE criteria<br />

Solveig Helgadottir, Olafur Indridason, Gisli Sigurdsson, Hannes Sigurjonsson,<br />

Thorarinn Arnorsson, Tomas Gudbjartsson, Iceland<br />

13:00 - 14:15 Lunch; visit the exhibition!<br />

STOCKHOLM, SWEDEN 15


FRIDAY, 21 AUGUST <strong>2009</strong><br />

14:15 - 15:45 S11 Symposium; Humanitarian Work in Cardiac Surgery Lecture room M2<br />

Moderators: Dan Lindblom and Eva Ahlgren<br />

Speakers:<br />

Stefan Peterson; Impact of Cardiovascular Diseases in Developing Countries<br />

Sylvain Chauvaud; Experiences by Chaine de l´espoir<br />

Gino Strada; Experiences by Emergency<br />

15:45 - 16:15 Coffee; visit the exhibition!<br />

16:15 - 17:15 S12 <strong>SATS</strong> Invited Lecture Lecture room M1<br />

Critically interpreting the mitral literature<br />

Anelechi Anyanwu introduced by Sten Samuelsson<br />

16:15 - 17:15 S13 SCANSECT Invited Lecture Lecture room E5<br />

Long Term Assist Devices previous, current and <strong>for</strong>ecast<br />

Heinz-Hermann Weitkemper introduced by Anne-Louise Bellaiche<br />

16:15 - 17:15 S14 SATNU Invited Lecture Lecture room M2<br />

Phychosocial aspects of heart failure<br />

Anna Strömberg introduced by Anita Tracey<br />

16:15 - 17:15 S15 Physiotherapists: Exchange of experiences Lecture room M3<br />

Moderators: Ulrika Thunström and Sofia Broman<br />

17:30 - 18:45 Awards and pre-dinner party<br />

18:45 Buses leave from Kistamässan<br />

19:30 Buffet dinner at the Stockholm City Hall<br />

21:15 Steamboat tour in the Stockholm Archipelago<br />

16 www.sats<strong>2009</strong>.org<br />

Stockholm Visitors Board - Christer Lundin


SATURDAY, 22 AUGUST <strong>2009</strong><br />

08:30 - 10:00 S16 <strong>SATS</strong> and SCANSECT; Cardiogenic shock in myocardial Infarction Lecture room M1<br />

Moderators: Anders Albåge and Jan Hultman<br />

Speakers:<br />

Lars Lund; Background and Current Guidelines <strong>for</strong> Intervention<br />

Lars Wiklund; Revascularization and Other Surgical Options<br />

Asghar Khaghani; Mechanical support<br />

08:30 - 09:30 S17 SATNU Invited Lecture Lecture room M2<br />

Reducing VAP in the ICU<br />

Eva Joelsson Alm introduced by Gunilla Barr<br />

08:30 - 10:00 S18 Physiotherapists Oral abstract session Lecture room M3<br />

Moderator: Gun Faager<br />

08:40 - 09:00 S18:1 Precautions after midline sternotomy. Are they necessary?<br />

Barbara Cristina Brocki, Charlotte Brun Thorup, Hanne Skindbjerg, Marianne Svalgaard,<br />

Jan Jesper Andreasen, Denmark<br />

09:00 - 09:20 S18:2 A randomized controlled trial on deep breathing exercises with positive expiratory<br />

pressure after cardiac surgery<br />

Charlotte Urell, Margareta Emtner, Marie Breidenskog, Elisabeth Westerdahl, Sweden<br />

09:20 - 09:40 S18:3 Physical activity on prescription (FaR®)-a long term follow-up of FaR® prescribed<br />

at a university hospital<br />

Susanna Wennman, Agneta Ståhle, Sweden<br />

09:30 - 10:30 SATNU General Assembly Lecture room M2<br />

10:00 - 10:30 <strong>SATS</strong> General Assembly Lecture room M1<br />

10:00 - 10:30 SCANSECT General Assembly Lecture room E5<br />

10:30 - 11:00 Pause; visit the exhibition!<br />

11:00 - 13:00 S19 Main topic 2; Transcatheter Valve Techniques Lecture room M2<br />

Moderator: Anders Jönsson<br />

History and Future of Aortic Valve Implantation<br />

Speaker: Ottavio Alfieri<br />

Invited discussant: Kenneth Pehrsson<br />

History and Future of Mitral Valve Interventions<br />

Speaker: Francesco Maisano<br />

Invited discussant: Reidar Winter<br />

13:00 - 13:15 Closing remarks Lecture room M2<br />

Jan Hultman<br />

STOCKHOLM, SWEDEN 17


Invited Speakers<br />

Ottavio Alfieri Ospedale San Raffaele, Milan, Italy<br />

Lars Algotsson Lund University Hospital, Lund, Sweden<br />

Maria Antonsson Uppsala University Hospital, Uppsala, Sweden<br />

Anelechi Anyanwu Mount Sinai Hospital, New York, USA<br />

Gerald Buckberg David Geffen School of Medicine, UCLA, Los Angeles, USA<br />

Sylvain Chauvaud La Chaîne de l’Espoir, Paris, France<br />

Maria Eriksson Karolinska University Hospital, Stockholm, Sweden<br />

Bodil Ivarsson Lund University Hospital, Lund, Sweden<br />

Eva Joelsson-Alm South Hospital, Stockholm, Sweden<br />

Asghar Khaghani Royal Brompton and Harefield Hospitals, London, UK<br />

Lars Lund Karolinska University Hospital, Stockholm, Sweden<br />

Francesco Maisano Istituto Scientifico San Raffaele, Milan, Italy<br />

Kenneth Pehrsson Karolinska University Hospital, Stockholm, Sweden<br />

Stefan Peterson Karolinska Institutet, Stockholm, Sweden<br />

Gino Strada Emergency, Milan, Italy<br />

Anna Strömberg Linköping University, Linköping, Sweden<br />

Charlotte Urell Uppsala University, Uppsala, Sweden<br />

Heinz-Hermann Weitkemper Bad Oeynhausen, Germany<br />

Elisabeth Westerdahl Örebro University Hospital, Örebro, Sweden<br />

Lars Wiklund Sahlgrenska University Hospital, Gothenburg, Sweden<br />

Reidar Winter Karolinska University Hospital, Stockholm, Sweden<br />

- Professor Gerald Buckberg, UCLA, Los Angeles, will give the annual Clarence Crafoord lecture, which usually<br />

is arranged during the Swedish annual meeting. Professor Buckberg was the 2007 Recipient of the American<br />

<strong>Association</strong> <strong>for</strong> <strong>Thoracic</strong> Surgery Scientific Achievement Award. He has published a large number of important<br />

articles in the fields of myocardial protection and left ventricular reconstruction.<br />

- Professor Anelechi Anyanwu, Director of Heart and Heart-Lung Transplantation at the Mount Sinai Medical<br />

Center, New York, will give a lecture on "How to read the mitral literature". His presentation might be considered as<br />

a follow-up to the very successful <strong>SATS</strong> postgraduate course in Copenhagen 2008, "From methodology to clinical<br />

evidence based decision making"<br />

Registration<br />

Registration & In<strong>for</strong>mation Desk<br />

Opening hours:<br />

Thursday, 20 August 10:00 - 17:30<br />

Friday, 21 August 07:30 - 17:30<br />

Saturday, 22 August 07:30 - 13:00<br />

Registration Fee (including VAT).<br />

On-site registration fee:<br />

• Delegates (members): SEK 5 100<br />

• Delegates (non-members): SEK 5 300<br />

• Nurses Physiotherapists and other health professionals fees: SEK 4 300<br />

• Nurses’ and Physiotherapists - only participation in nurses or<br />

physiotherapists sessions on Friday and Saturday: SEK 1 800<br />

• Accompanying persons: SEK 1 500<br />

On-site registration - please note some of the events might be fully booked.<br />

Cancellation & refund policy<br />

Credit cannot be given <strong>for</strong> unattended event, late arrivals or early departures.<br />

Hotel Accommodation<br />

The registration desk will handle inquires related to hotel accommodation.<br />

18 www.sats<strong>2009</strong>.org


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Social <strong>Program</strong>me<br />

All events are available <strong>for</strong> participants and accompanying persons and should have been prebooked on the<br />

registration <strong>for</strong>m. For late bookings – please contact the registration desk <strong>for</strong> availability.<br />

A ticket is mandatory <strong>for</strong> entrance and will be handed out at the registration desk.<br />

Gala Dinner at Solliden, Skansen<br />

Thursday, 20 August at 19.30.<br />

The Gala Dinner will be held at Solliden Restaurant at Skansen, with a fabulous view of the Stockholm waterfront.<br />

The restaurant is located at Skansen, which is the world’s oldest open-air museum, founded in 1891.<br />

The Solliden Restaurant was built 1950-1952 and several well-known artists were commissioned to decorate the<br />

new restaurant, among them Hilding Linnqvist who painted the large fresco on the staircase called “The Story of<br />

Sweden”. This is a festive opportunity <strong>for</strong> all participants to meet and socialize.<br />

SEK 500 <strong>for</strong> registered delegates<br />

SEK 700 <strong>for</strong> non-registered delegates<br />

Dress code: Business suit/suit and tie.<br />

Individual transport.<br />

Reception at the Stockholm City Hall<br />

Friday, 21 August at 19.30.<br />

The City of Stockholm invites you to a buffet dinner at the Stockholm City Hall. The City Hall was designed by<br />

architect Ragnar Östberg in 1923 and is beautifully situated on the Riddarfjärden waterfront in central Stockholm.<br />

It is home to the central administration of the city. However, the City Hall is mostly famous <strong>for</strong> the Nobel Prize<br />

festivities, which are held in the Blue Hall every year on 10 December.<br />

By invitation from the City of Stockholm. Pre-registration is necessary.<br />

Transportation from the conference venue will be arranged.<br />

Steam boat tour in Stockholm Archipelago<br />

Friday, 21 August at 21.15.<br />

Experience the beautiful inner archipelago of Stockholm onboard a traditional steam boat. Enjoy a cup of coffee<br />

while viewing the typical archipelago sights and Stockholm’s magnificent location between Lake Mälaren and the<br />

sea. Extra drinks can be purchased in the bar onboard.<br />

SEK 100 <strong>for</strong> registered delegates<br />

SEK 200 <strong>for</strong> non-registered delegates<br />

20 www.sats<strong>2009</strong>.org


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General In<strong>for</strong>mation<br />

in alphabetic order<br />

Audio-visual facilities<br />

All lecture halls are equipped with PC and PowerPoint.<br />

Business hours & Shopping<br />

Shops are open between 10.00 and 18.00 hrs on weekdays and from 10.00 to 15.00 hrs on Saturdays. Shops in the<br />

City centre have extended opening hours, some even on Sundays between 12.00 and 16.00 hrs. The main shopping<br />

streets in the centre of Stockholm are: Hamngatan, Biblioteksgatan, Drottninggatan and Västerlånggatan in the Old<br />

Town. The Kista Galleria (shopping mall) with its´ 125 shops is only a few minutes walk from the conference venue.<br />

Open 7 days a week between 10.00-21.00.<br />

Certificate of Attendance<br />

A Certificate of Attendance is inserted in the conference bag.<br />

Check – in/-out<br />

Hotel check-in time is 15.00 hrs or later. Check-out time is 12.00.<br />

Climate and Clothing<br />

The average temperature in August is around 18-20°C (approx. 65-68°F).<br />

Conference Language<br />

The official language of the conference is English. There will be no simultaneous interpreting.<br />

Conference Venue<br />

Kistamässan. Kista Expo Center. For in<strong>for</strong>mation on the venue, please visit the venue website:<br />

www.kistamassan.com. Address: Kistamässan, Kistagången 1, 164 22 KISTA. Phone: +46 8-50665000<br />

Currency & Credit Cards<br />

The currency in Sweden is the Swedish Krona, SEK. A currency calculation can be found online at:<br />

www.x-rates.com/calculator.html<br />

Commonly accepted credit cards in hotels, restaurants and shops are American Express, Diners Club, Visa, Master<br />

Card and Euro card. Restaurants and shops generally display signs indicating what cards they accept. The registration<br />

desk accepts all these cards.<br />

Evaluation of the conference<br />

Shortly after the conference, an evaluation <strong>for</strong>m will be e-mailed to you. We would appreciate if you could fill in the<br />

<strong>for</strong>m as it is important <strong>for</strong> us to know what you think of this meeting and what we can improve to the next meeting.<br />

Exhibition<br />

The commercial exhibition will be held in conjunction with the conference, adjacent to the session halls.<br />

Insurance<br />

Neither the Conference Organisers nor the Conference Secretariat accept any liability <strong>for</strong> personal injuries sustained,<br />

or <strong>for</strong> loss or damage to property belonging to conference participants, either during or as a result of the conference.<br />

It is strongly recommended that you purchase an insurance policy of your choice as you register <strong>for</strong> the conference<br />

and book your travel. The insurance should be purchased in advance.<br />

Name Badges<br />

The delegate’s name badge will be provided at the registration desk. All delegates are required to wear the badge<br />

throughout the conference. Only badge holders will be admitted to the sessions.<br />

On-site registration<br />

On-site registrations will be accepted, however availability of hotel accommodation and participation in the social<br />

tours/events at that time may be severely limited.<br />

22 www.sats<strong>2009</strong>.org


Smoking policy<br />

Kistamässan and the evening venues are all non smoking. Smoking is banned in public places in Stockholm, on<br />

public transport, in stores, restaurants and most pubs. Hotels offer special rooms <strong>for</strong> smokers. Please indicate your<br />

request on the registration <strong>for</strong>m, when you make your hotel reservation.<br />

Speakers Ready room<br />

Presenters are kindly requested to hand in their presentation to the technicians in the Speaker´s Ready room, E3,<br />

at least 2 hours prior your session starts. If you bring your own laptop, please be sure to visit the technicians be<strong>for</strong>e<br />

your lecture in order to ensure the right equipment is in place.<br />

Speakers´Ready room, E 3 – opening hours<br />

Thursday, 20 August: 10:00 – 18:00<br />

Friday, 21 August: 07:30 – 17:00<br />

Saturday, 22 August: 07:30 – 13:00<br />

The lecture halls will be equipped with PC with PowerPoint.<br />

Time zone<br />

Sweden is 1 hour ahead of Greenwich Mean Time (GMT).<br />

Tourist in<strong>for</strong>mation<br />

For tourist in<strong>for</strong>mation about Stockholm and Sweden, please visit the website: www.stockholmtown.com, or contact<br />

the Tourist Centre on phone: +46 8 508 28 508 or info@svb.stockholm.se.<br />

Transportation<br />

Stockholm has a well-developed local transport system. For more in<strong>for</strong>mation please visit SL (Stockholm’s public<br />

transport website), www.sl.se.<br />

Airports and Transport<br />

Arlanda Airport is located 42 km north of Stockholm.<br />

The Arlanda Express is the train service that links Stockholm City with the Airport. Book your Arlanda Express<br />

ticket in advance at the same time you register to the conference. MCI offers discounted tickets <strong>for</strong> travel with the<br />

Arlanda Express train from Arlanda to Stockholm. Your confirmation letter will serve as a ticket when presented to<br />

the train conductor. SEK 220 each way.<br />

Other ways to reach the city:<br />

Taxi: We recommend that you request a fixed price from the airport to the city, approx. SEK 450 - 550. Arlanda<br />

Airport-Kistamässan approx. SEK 385.<br />

Bus: There is direct bus connection from Arlanda Airport to the City Terminal in Stockholm. From Saturday, August<br />

22 there is also a direct connetion Kistamässan-Arlanda Airport. The journey from the airport to central station,<br />

takes about 40 minutes. The bus leaves Arlanda airport every 10 minutes. For in<strong>for</strong>mation on the airport buses<br />

(prices, time tables etc.) please visit www.flygbussarna.se<br />

Bromma Airport<br />

Bromma is Stockholm's city airport and your fastest alternative to and from the Swedish capital. Bus: There is direct<br />

bus connection from Bromma Airport to the City Terminal in Stockholm. From Saturday, August 22 there is also a<br />

direct connection Kistamässan – Bromma airport, adapted to flight arrivals and departures. Driving time from central<br />

Stockholm is approx 20 minutes. From Bromma airport to Kistamässan approx 15 minutes. Local transport (SL):<br />

You can also catch a local bus to/from Stockholm-Bromma airport. Please visit www.sl.se <strong>for</strong> more in<strong>for</strong>mation.<br />

Taxi: We recommend that you request a fixed price from the airport to the city, approx.SEK 220. Bromma Airport-<br />

Kistamässan approx. SEK 210.<br />

For in<strong>for</strong>mation on the airport buses (prices, time tables etc.) please visit www.flygbussarna.se<br />

Travel to/from Stockholm central station to/from Kistamässan:<br />

By underground: Catch the Blue line from Rådhuset, direction 'Akalla' or the Green line direction 'Hässelby' and<br />

change trains at Fridhemsplan to Blue line 'Akalla'. The stations Kungsträdgården and T-Centralen are closed during<br />

the summer. Get off at the stop 'Kista' (15-20 min), a 10 minute walk to Kistamässan.<br />

By commuter train: Catch the commuter train from Stockholm central with the direction 'Märsta'. You get off at the<br />

stop 'Helenelunds station' (12 min travel) a 5 minute walk to Kistamässan.<br />

STOCKHOLM, SWEDEN 23


Visiting Stockholm<br />

Welcome to Stockholm, the Royal Capital of Sweden. Discover a city like no other - a city built on<br />

14 islands, where you are never far from the water. Well-preserved medieval buildings stand alongside<br />

modern architecture. Stockholm is also home of the Nobel Prize. And just outside the city, the archipelago<br />

of 24 000 islands is waiting to be explored.<br />

Stockholm is a city of contrasts - water and islands, history and innovation, small town and big city, short winter days<br />

and long, light summer nights - with a dazzling array of impressions. Thanks to the city’s compact size, you can see<br />

and do most things in a short space of time - which makes it a perfect destination <strong>for</strong> city breaks or longer stays, all<br />

the year round.<br />

Discover a city of contrasts. Go back 750 years in time and feel the medieval atmosphere of the Old Town<br />

“Gamla Stan” as you wander through the narrow streets. Stockholm has got history - but also the latest in<br />

fashion and IT. The trendy Stockholmers are often used as a test market by international companies, as they<br />

are quick to pick up on the latest trends. This is most obvious on the island of Södermalm, a hotbed of fashion,<br />

young culture and entertainment.<br />

Stockholm is one third water, one third green belt and one third city. The island of Djurgården, the world´s first<br />

National City Park, is only a short walk from the pulse of the inner city. Stockholmers and visitors alike come here<br />

to relax in the leafy shade and rest their eyes on green.<br />

Stockholm’s excellent transport links mean the city can offer reasonable access <strong>for</strong> all participants.<br />

Stockholm is very well positioned with most of Europe within three hours reach. It is a genuine meeting point in every<br />

respect and an increasingly important hub <strong>for</strong> flights to major destinations in the Baltic Sea Region, European Union<br />

and the expansive global community.<br />

Useful links<br />

Stockholm Visitor’s Guide<br />

This is the site where you can find nearly everything you need to know as a tourist in Stockholm:<br />

www.stockholmtown.com<br />

Guided boat tours<br />

During the period of April-December we highly recommend a 1 to 2 hour guided boat tour under the bridges of<br />

Stockholm:<br />

www.stockholmsightseeing.com<br />

Bus tours<br />

Guided bus tours around Stockholm, offered in eleven different languages, are available throughout the year:<br />

www.citysightseeing.com<br />

Boat tours in the archipelago and Lake Mälaren<br />

If you so only have one night or one day off in Stockholm, you cannot miss our archipelago. It consists of 24,000<br />

islands, of which only 3,000 are inhabited. Take a short trip of only a few hours, preferably during the evening with<br />

dinner onboard, to this unique place in the world.<br />

Choose Strömma Kanalbolaget if you prefer travelling by a steamboat or a boat from the turn of the century:<br />

www.strommakanalbolaget.com<br />

Choose Cinderellabåtarna if you want to see the whole archipelago, at 30 knots per hour, in only a few hours:<br />

www.cinderellabatarna.com<br />

Shopping in the city<br />

Here are some good links to great shopping in Stockholm city centre. NK is an exclusive department store: www.nk.se<br />

Sturegallerian is a stylish mall in the middle of the hottest district in town: www.sturegallerian.se<br />

Gallerian is one of the first malls in Sweden: www.gallerian.se<br />

24 www.sats<strong>2009</strong>.org


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Kistamässan Overview<br />

KONFERENS<br />

Ground Floor<br />

KONFERENSENTRÉ<br />

Torshamnsgatan 18 c<br />

E10<br />

VIP-Lounge<br />

E9<br />

www.kistamassan.com<br />

E7<br />

E5<br />

26 www.sats<strong>2009</strong>.org<br />

E8<br />

E6<br />

WC WC<br />

Presscenter<br />

KONFERENSLOBBY<br />

E6<br />

GARDEROB<br />

RECEPTION<br />

E1<br />

E2<br />

E4<br />

HWC<br />

E3<br />

WC<br />

WC<br />

MÄSSHALL | ENTRÉHALL<br />

E3<br />

Speakers<br />

ready room<br />

E4


Kistamässan Overview<br />

KONFERENS<br />

First Floor<br />

M1 M2<br />

M1 M2<br />

Exhibition<br />

HALL & 1<br />

Poster area<br />

HALL 2<br />

www.kistamassan.com<br />

Mässplan Entresolplan<br />

M3<br />

M4 M3<br />

STOCKHOLM, SWEDEN 27<br />

M5


Exhibition<br />

Exhibition opening hours<br />

Thursday 20 August: 12:00 - 17:30<br />

Friday 21 August: 08:00 - 18:45<br />

Saturday 22 August: 08:00 - 13:30<br />

List of Exhibitors<br />

Company Stand No.<br />

Aesculap AG B:20<br />

ATS Medical E:14<br />

Baxter Medical AB B:30<br />

Covidien Sverige AB C:20<br />

Carmel Pharma AB C:21<br />

Dicamed AB B:27<br />

Dräger Medical Sverige AB B:10<br />

Edwards Lifesciences E:21<br />

Hemax Medical A/S B:15<br />

Johnson & Johnson Nordic C:25<br />

Kanmed AB B:15<br />

KLS Martin Group B:12<br />

KRAUTH Surgical GmbH C:11<br />

Maquet Nordic AB D:31<br />

Master Surgery Systems AS B:21<br />

Medela Medical AB B:13<br />

Mediplast AB C:23<br />

Medi-Stim ASA E:31<br />

Medtronic AB E:11<br />

Orion Pharma AB C:13<br />

Philips Healthcare B:09<br />

Qualiteam s.r.l. B:24<br />

<strong>Scandinavian</strong> Cardiovascular Journal B:22<br />

Sorin Group Scandinavia AB C:10<br />

St. Jude Medical Sweden AB E:25<br />

SWEDISH ORPHAN INTERNATIONAL AB B:07<br />

Synthes AB B:11<br />

TERUMO D:30<br />

Vingmed Svenska AB C:30<br />

28 www.sats<strong>2009</strong>.org


M2<br />

M1<br />

Exhibition Floor Plan<br />

STOCKHOLM, SWEDEN 29


Sponsors<br />

The organisers acknowledge the following organisations <strong>for</strong> their generous contribution:<br />

Gold Sponsor<br />

Silver Sponsors<br />

Bronze Sponsors<br />

30 www.sats<strong>2009</strong>.org


Authors' Index<br />

A<br />

Aasmundstad, Tor S06:7<br />

Aazami, Mathias P01:41, P01:26<br />

Abdel Aal, Mohamed P01:19, P01:20<br />

Agger, Peter P01:03, P01:04<br />

Ahlsson, Anders S09:4<br />

Ahn, Henrik S05:1, P01:43, S05:2<br />

Aittomäki, Kristiina P01:32<br />

Alfredsson, Hordur P01:16<br />

Alfredsson, Joakim S10:4<br />

Alho, Hanni P01:32<br />

Aljassim, Obaid S05:3<br />

Andersen, Henning Rud S01:4<br />

Andersen, Karl P01:06<br />

Andersen, Knut S. P01:36<br />

Andersen, Lars W. S01:3<br />

Andersen, Marit S07:6<br />

Anderson, Rober H. P01:04<br />

Andreasen, Jan Jesper S18:1<br />

Andreassen, Arne K. P01:29, P01:30<br />

Andresen, Brith S07:6<br />

Arnorsson, Thorarinn<br />

P01:23, S10:6, P01:12<br />

Asgeirsson, Hilmir P01:15<br />

Astradsson, Thorsteinn S06:6<br />

Avlonitis, Vassilios S09:5<br />

B<br />

Balasubramanian, Sendhil Kumaran<br />

S09:5<br />

Baranowski, Jacek<br />

S05:1, P01:43, S05:2<br />

Bech-Hanssen, Odd S05:3<br />

Beck, Hans J. P01:14<br />

Bellaiche, Anne Louise S06:8<br />

Benetis , Rimantas P01:42<br />

Berg, Sören S07:7, S10:4<br />

Bergman, Per S09:7, P01:13, S01:5<br />

Bjessmo, Staffan S01:2<br />

Bjornholt, Jorgen P01:30<br />

Björnsson, Jóhannes P01:17<br />

Blomquist, Sten S10:3<br />

Bondo Jørgensen, Louise P01:05<br />

Borger, Michael Andrew S06:5<br />

Breidenskog, Marie S18:2<br />

Brocki, Barbara Cristina S18:1<br />

Brodin, Daniel P01:13, S01:5<br />

Brondén, Björn S10:3<br />

Brorsson, Bengt P01:25<br />

Böing, Ingeborg S01:4<br />

C<br />

Chen, Bosheng S10:1, S10:2<br />

Chen, Ju S10:2, S10:1<br />

Christensen, John S05:4<br />

D<br />

Daavoy, Grethe S07:3<br />

Dainius, Karciauskas P01:42<br />

Dashwood, Michael S09:3<br />

De Petris, Luigi S01:5<br />

Dreifaldt, Mats S09:3<br />

Drevdal, Julie P01:45<br />

Dunning, Joel S09:5<br />

Døhlen, Gaute S07:6<br />

E<br />

Eggen Hermansen, Stig P01:28<br />

Egle, Ereminiene P01:42<br />

Ehnsiö, Gustaf S10:4<br />

Eikemo, Hege S06:3<br />

Eliassen, Finn S06:3<br />

Ellensen, Vegard Skalstad P01:36<br />

Emtner, Margareta S18:2<br />

Englund, Anders S09:4<br />

Eriksson, Heidi P01:31<br />

Eyjolfsson, Atli S10:3<br />

F<br />

Falk, Volkmar S06:4<br />

Farstad, Marit S06:3<br />

Fengsrud, Espen S09:4<br />

Fiane, Arnt E.<br />

S06:7, S07:4, P01:29, P01:30<br />

Fluger, Ivo P01:07<br />

Fosse, Erik S07:6<br />

Frandsen, Jesper P01:04<br />

Franzén, Stefan P01:37<br />

Freter, Wolfgang<br />

S05:2, S05:1, P01:43<br />

Frey, Joana P01:08<br />

Fritz-Hansen, Thomas S05:4<br />

STOCKHOLM, SWEDEN 31<br />

G<br />

Gardarsdottir, Marianna P01:06<br />

Geiran, Odd R. S06:7, P01:29, P01:30<br />

Gill, Michael S09:5<br />

Gjeilo, Kari Hanne S07:5<br />

Gluud, Christian S01:3<br />

Goodwin, Andrew S09:5<br />

Gottfredsson, Magnus P01:11<br />

Greve, Helle S03:6<br />

Grosen, Kasper S03:2<br />

Grosse, F. Oliver S06:5<br />

Grosse, Frank Oliver S06:4<br />

Grulichova, Jana P01:07<br />

Gudbjartsson, Tomas<br />

P01:06, P01:11, P01:12, P01:14,<br />

P01:15, P01:16, P01:17, P01:18,<br />

P01:23, S06:6, S09:2, S10:6<br />

Gude, Einar P01:29, P01:30, S07:4<br />

Gudjonsdottir, Marta P01:14, P01:15<br />

Gudmundsdottir, Ingibjorg P01:11<br />

Gudmundsson, Gunnar P01:17<br />

Gunnarsson, Gunnar Thor P01:06<br />

Gunnarsson, Sverrir I. P01:14, P01:15<br />

H<br />

Haaverstad, Rune<br />

P01:36, P01:45, S06:3, S07:3<br />

Hajek, Roman P01:07<br />

Han, Jie S10:1, S10:2<br />

Harjula, Ari P01:31<br />

Hasenkam, J Michael P01:03, S01:1<br />

Haugen, Arvid S07:3<br />

Haukeland, Unni Kleppe P01:45<br />

Helgadottir, Solveig S10:6<br />

Hiippala, Seppo<br />

Hjortdal, Vibeke E.<br />

P01:22<br />

P01:03, P01:04, S01:4, S03:3<br />

Hollman Frisman, Gunilla S07:7<br />

Holm, Jonas P01:40<br />

Holm, Peter P01:44<br />

Holme, Susanne Juel S05:4<br />

Holter, Marianne S07:4<br />

Holzhey, David S06:4<br />

Hornbech, Kåre S09:1<br />

Hreinsson, Hreinsson P01:12<br />

Hua, Ping S10:1, S10:2<br />

Huhtala, Heini S03:1<br />

Håkanson, Erik P01:40<br />

Hägglund, Doris S07:2<br />

Hämmäinen, Pekka P01:31<br />

Høyland, Vivian S06:7


I<br />

Ibsen, Dorthe S03:6<br />

Indridason, Olafur S10:6<br />

Ingadottir, Brynja S07:8<br />

Ingerslev, Jørgen S09:6<br />

Isaksson, Helgi P01:16<br />

Isgro, Frank S05:7<br />

Ivert, Torbjörn P01:25<br />

J<br />

Jakobsen, Carl-Johan S01:4<br />

Javangula, Kalyana<br />

P01:21, P01:33, P01:34, P01:35<br />

Jensen, Henrik S01:1<br />

Jensen, Mogens P. S03:2<br />

Jensen, Morten S01:1<br />

Jeppsson, Anders<br />

P01:01, P01:02, S05:3, S06:1, S06:2<br />

Joergensen, Inge Selchau P01:48<br />

Johannsson, Kristinn B.<br />

P01:14, P01:15<br />

Jonasson, Jon Gunnlaugur S09:2<br />

Jonsson, Steinn P01:16<br />

Jurga, Juliane P01:27<br />

Jyrala, Aarne S05:6<br />

Järvelä, Kati S03:1<br />

Jönsson, Anders P01:44<br />

Jönsson, Henrik S10:3<br />

K<br />

Kaartinen, Maija P01:39<br />

Kalabic, Maria S06:1<br />

Karciauskas, Dainius P01:42<br />

Kargar, Faranak P01:26, P01:41<br />

Karlsen, Harald S06:7<br />

Karlsson, Mats S09:3<br />

Kay, Gregory L S05:6<br />

Kendall, Simon S09:5<br />

Kiessling, Arndt-H. S05:7<br />

Kjøller, Morten S05:4<br />

Klaaborg, Kaj-Erik S01:4<br />

Klemenzson, Gudmundur P01:06<br />

Klepstad, Pål S07:5<br />

Klungreseth, Oddvar S06:8<br />

Kolackova, Martina P01:51<br />

Kornberger, Angela S05:7<br />

Kraemer, Klaus S06:4, S06:5<br />

Krejsek, Jan P01:51<br />

Kubicek, Jaroslav P01:51<br />

Kudlova, Manuela P01:51<br />

L<br />

Laine, Seppo S10:5<br />

Lange, Aase S03:5<br />

Langova, Katerina P01:07<br />

Laurikka, Jari S10:5<br />

Laursen, Vibeke S03:3<br />

Lehmann, Andreas S05:7<br />

Lemström, Karl P01:31<br />

Lindahl, Sten GE S01:6<br />

Lindberg, Harald S07:6<br />

Linde, Peter S09:4<br />

Lindvall, Bo S01:2<br />

Lindvall, Gabriella S01:2<br />

Loesch, Andrzej S09:3<br />

Lonský, Vladimir<br />

P01:07, P01:09, P01:51<br />

Lund, Jens S01:3<br />

Lunkenheimer, Paul P. P01:04<br />

Lydersen, Stian S07:5<br />

Lygren, Heidi P01:45<br />

M<br />

Maaranen, Pasi S03:1<br />

Maasilta, Paula P01:32, P01:39<br />

Madsen, Jan K. S01:3<br />

Magnusson, Björn P01:14, P01:15<br />

Malek, Hadi P01:26<br />

Mandak, Jiri P01:51<br />

Manilla, Maria N. P01:27<br />

Mariusdottir, Elin P01:18<br />

Mathisen, Lars S07:6<br />

Mohebi, Ahmad P01:41<br />

Mohr, Friedrich Wilhelm S06:4, S06:5<br />

Molitor, Martin P01:07, P01:09<br />

Moller, Pall S09:2<br />

Mongstad, Arve S06:3<br />

Muddle, John S09:3<br />

Murkka, Timo S03:1<br />

Murugesh, Shamini S07:3<br />

Mushtaq, Abid P01:34<br />

Musilová, Petra P01:32<br />

Myrmel, Truls P01:28<br />

Mäki, Kaisa P01:10<br />

Møller, Christian H S01:3<br />

Møller-Madsen, Maria Kirstine P01:03<br />

32 www.sats<strong>2009</strong>.org<br />

N<br />

Nair, Unnikrishnan<br />

P01:21, P01:33, P01:34, P01:35<br />

Neher, Michael S05:7<br />

Nielsen, Eva P01:04<br />

Nielsen, Hans Henrik Møller S01:4<br />

Nielsen, Niels Erik<br />

P01:43, S05:1, S05:2<br />

Nielsen, Peter Fast S06:8<br />

Nielsen, Sten Lyager S01:1<br />

Niemi, Anu S03:1<br />

Nilsson, Ulrica S03:4<br />

Njåstad, Anita P01:45<br />

Noohi, Freidoun P01:41<br />

Norderfeldt, Joakim S10:4<br />

Norgren, Lars S09:3<br />

Norum, Hilde S06:7<br />

Nylander, Eva<br />

P01:37, P01:43, S05:1, S05:2<br />

Nyman, Jesper P01:27<br />

O<br />

Oddsson, Saemundur J. P01:23<br />

Olafsdottir, Heida Steinunn S07:8<br />

Olafsdottir, Thora Sif P01:17<br />

Oterhals, Kjersti P01:45<br />

Owens, Andrew S09:5<br />

P<br />

Papaspyros, Sotoris<br />

P01:21, P01:33, P01:34<br />

Parvaiz, Imran S03:3<br />

Pellegrini, Carlo S05:5<br />

Peng, Jiangzhou S10:1, S10:2<br />

Perko, Mario S01:3<br />

Perrotta, Sossio S05:3<br />

Persson, Jenny P01:49<br />

Petursdottir, Vigdis P01:06<br />

Piilonen, Anneli P01:31<br />

Pilegaard, Hans K. S03:2<br />

Pooraliakbar, Hamid-Reza P01:26<br />

Povilas, Jakuska P01:42<br />

Pozzi, Matteo S05:5<br />

Påhlman, Carin P01:37<br />

Päiväniemi, Outi P01:32


R<br />

Raffa, Giuseppe S05:5<br />

Raoul, Bergner S05:7<br />

Rasmussen, Tina Seidelin P01:50<br />

Ravn, Jesper B. S09:1<br />

Rexius, Helena P01:01, S06:1, S06:2<br />

Rimeika, Danguole S01:6<br />

Ringgaard, Steffen P01:03, S01:1<br />

Roman-Emanuel, Christine<br />

P01:01, P01:02, S07:2<br />

Ruan, Xinhua S10:5<br />

Rylander Hagson, Pauline P01:47<br />

S<br />

Saggau, Werner S05:7<br />

Salminen, Ulla-Stina<br />

P01:10, P01:32, P01:39<br />

Samiei, Niloofar P01:41<br />

Sarkar, Nondita P01:27<br />

Sartipy, Ulrik S01:2<br />

Sarunas, Kinduris P01:42<br />

Savasta, Marcello S05:5<br />

Schaarschmidt, Jan S06:4, S06:5<br />

Seeburger, Joerg S06:5<br />

Segadal, Leidulf P01:36, P01:45<br />

Sigfusson, Nikulas P01:18<br />

Sigurdsson, Gisli S10:6<br />

Sigurjonsson, Hannes<br />

P01:06, P01:12, P01:23, S10:6<br />

Simek, Martin P01:07, P01:09<br />

Simonardottir, Liney S06:6<br />

Simpanen, Jarmo P01:38<br />

Sipponen, Jorma P01:10, P01:31<br />

Sisto, Tero S03:1<br />

Sjögren, Johan P01:11<br />

Skindbjerg, Hanne S18:1<br />

Slettebø, Haldor S07:3<br />

Smarason, Njall P01:12<br />

Smerup, Morten<br />

P01:03, P01:04, S01:1<br />

Soefteland, Eirik S07:3<br />

Soisalon-Soininen, Sari P01:39<br />

Sorensen, Gro P01:29, P01:30, S07:4<br />

Souza, Domingos S09:3<br />

Sprogøe, Pia S06:8<br />

Steinbrüchel, Daniel A.<br />

S01:3, S09:1, P01:05<br />

Steingrímsson, Steinn P01:11<br />

Stenseth, Roar S07:5<br />

Strömberg, Anna S07:7<br />

Ståhle, Agneta S18:3<br />

Sundh, Marie P01:47<br />

Suojaranta-Ylinen, Raili P01:22, P01:39<br />

Svalgaard, Marianne S18:1<br />

Svedjeholm, Rolf<br />

P01:24, P01:40, S07:7<br />

Svegby, Henrik P01:08<br />

Sveinsdottir, Herdis S07:8<br />

Svenarud, Peter<br />

P01:08, P01:27, S01:2<br />

Svensson, Gunnar S05:3<br />

Sørensen, Benny S09:6<br />

T<br />

Tamás, Éva<br />

P01:37, P01:43, S05:1, S05:2<br />

Tang, Mariann S03:3, S09:6<br />

Tarkka, Matti S10:5<br />

Terp, Kim S09:6<br />

Thiara, Amrit Singh S06:7<br />

Thimour-Bergström, Linda<br />

P01:01, P01:02<br />

Thorsteinsdottir, Steinunn Arna<br />

P01:46<br />

Thorsteinsson, Hunbogi P01:16<br />

Thorup, Charlotte Brun S18:1<br />

Thuesen, Leif S01:4<br />

Tian, Yikui S10:5<br />

Torfason, Bjarni S06:6<br />

Tornvall, Per P01:27<br />

Tracey, Anita P01:48, P01:50<br />

Tyden, Hans S09:4<br />

U<br />

Urell, Charlotte S18:2<br />

V/W<br />

Wahba, Alexander S07:5<br />

Vainikka, Tiina<br />

P01:10, P01:32, P01:39<br />

Vakkuri, Anne P01:10<br />

Wallby, Lars P01:43, S05:1, S05:2<br />

Walsoe, Charlotte S07:1<br />

Valsson, Felix S06:6<br />

van der Linden, Jan<br />

P01:08, P01:27, S01:2<br />

Wang, Youyu S10:1<br />

Vanky, Farkas P01:24, P01:40<br />

Wei, Minxin S10:5<br />

Wennervirta, Johanna P01:10<br />

Wennman, Susanna S18:3<br />

Vento, Antti P01:39<br />

Werkkala, Kalervo P01:38<br />

Westerdahl, Elisabeth S18:2<br />

Vidarsdottir, Halla S09:2<br />

Wierup, Per S01:1, S09:6<br />

Vigano', Mario S05:5<br />

Wiklund, Claes U S01:6<br />

Virolainen, Juha P01:31<br />

Wirup, Per P01:38<br />

Volt, Martin P01:51<br />

STOCKHOLM, SWEDEN 33<br />

X<br />

Xue, Lei S10:2<br />

Y<br />

Yaghoubi, Nahid P01:26<br />

Yang, Yanqi S10:1, S10:2<br />

Z<br />

Záleaák, Bohumil P01:09<br />

Å<br />

Ågren, Susanna S07:7<br />

Ångerman-Haasmaa, Susanne P01:10<br />

Ö<br />

Önsten, Linda P01:01, S06:2<br />

Övrebö, Bente S06:3


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<strong>for</strong> more in<strong>for</strong>mation.<br />

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Sweden: +46 40 20 48 50, Norway: +47 22 23 98 40, Denmark: +45 70 22 34 38, Finland: +358 20 743 00 41


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Biocor, Epic, FlexFit, Linx, ST. JUDE MEDICAL, the nine-squares symbol and MORE CONTROL. LESS RISK. are trademarks and service marks<br />

of St. Jude Medical, Inc. and its related companies. ©<strong>2009</strong> St. Jude Medical. All Rights Reserved.


ABSTRACTS<br />

STOCKHOLM, SWEDEN 37


S01<br />

<strong>SATS</strong> AWARD NOMINEES ORAL ABSTRACT SESSION<br />

S01:1<br />

IMPACT OF PAPILLARY MUSCLE RELOCATION AS ADJUNCT PROCEDURE TO MITRAL RING<br />

ANNULOPLASTY IN FUNCTIONAL ISCHEMIC MITRAL REGURGITATION<br />

Jensen Henrik 1 , Jensen Morten 2 , Smerup Morten 3 , Wierup Per 3 , Ringgaard Steffen 4 ,<br />

Hasenkam J. Michael 3 , Nielsen Sten Lyager 3<br />

1) Aarhus University Hosptital, Skejby, 2) Aarhus Univ. Dept. of Biomed. Eng.,<br />

3) Aarhus University Hospital, Skejby, 4) Aarhus Univ. Hosp., MRI-Research Centre, Denmark<br />

Background<br />

The optimal surgical treatment in functional ischemic mitral regurgitation(FIMR) remains controversial. Recently, a<br />

posterior papillary muscle relocation(PMR) technique as adjunct procedure to ring annuloplasty has been proposed<br />

to prevent recurrent FIMR. In the present study we used 3D cardiac magnetic resonance imaging to assess the<br />

impact of relocating both papillary muscles as adjunct procedure to down-sized ring annuloplasty on mitral leaflet<br />

coaptation geometry in FIMR pigs.<br />

Methods<br />

Eleven FIMR pigs were randomized to down-sized ring annuloplasty(RA, n= 6) or RA combined with PMR(RA+PMR,<br />

n=5). In the RA+PMR group a 2-0 Gore-tex suture was attached to each trigone, exteriorized through the<br />

corresponding papillary muscle, mounted on an epicardial pad and tightened to relocate the myocardium adjacent to<br />

the anterior and posterior papillary muscles 5 and 15 mm, respectively. Using 3D magnetic resonance imaging the<br />

impact from these interventions on leaflet geometry was assessed.<br />

Results<br />

Following statistically significant(p


S01:3<br />

30-DAY OUTCOMES IN HIGH RISK-PATIENTS RANDOMIZED TO OFF-PUMP OR ON-PUMP CORONARY<br />

BYPASS SURGERY<br />

Møller Christian H 1 , Perko Mario 1 , Lund Jens 1 , Andersen Lars W. 1 , Madsen Jan K. 2 ,<br />

Gluud Christian 1 , Steinbrüchel Daniel A 1<br />

1) Rigshospitalet, 2) Gentofte Hospital, Denmark<br />

Background<br />

Coronary artery bypass grafting (CABG) per<strong>for</strong>med with (on-pump) and without (off-pump) cardiopulmonary bypass<br />

seems safe and results in about the same outcome in low-risk patients. Observational studies indicate that off-pump<br />

surgery may provide more benefit in high-risk patients. Our objective was to compare outcomes in high-risk patients<br />

randomized to CABG with or without cardiopulmonary bypass.<br />

Methods and Results<br />

We randomly assigned 341 patients with a EuroSCORE ≥ 5 and 3-vessel coronary disease to undergo on-pump<br />

versus off-pump CABG. Patients were followed up through the Danish National Patient Registry. The primary<br />

outcome was a composite of adverse cardiac and cerebrovascular events (i.e., all-cause mortality, acute myocardial<br />

infarction, cardiac arrest with successful resuscitation, low cardiac output syndrome/cardiogenic shock, stroke, and<br />

coronary reintervention). An independent event committee blinded <strong>for</strong> treatment allocation assessed the outcomes.<br />

Baseline characteristics were well balanced between groups, and the mean number of grafts per patient did not<br />

differ significantly between groups (3.22 in off-pump and 3.34 in on-pump, P = 0.11). No significant difference in the<br />

composite primary outcome (15% vs 17%, P = 0.48) or the individually components were found at 30-day follow-up.<br />

Fewer grafts were per<strong>for</strong>med to the lateral part of the left ventricle territory during off-pump surgery (0.97 vs 1.14<br />

after on-pump surgery; P = 0.01). Conclusion - Both off- and on-pump CABG can be per<strong>for</strong>med in high-risk patients<br />

with low short-term complications. Off-pump surgery seems to be associated with a reduced number of grafts to the<br />

lateral territory of the left ventricle.<br />

S01:4<br />

CATHETER BASED AORTIC VALVE IMPLANTATION – RESULTS FROM THE FIRST 50 PATIENTS<br />

Nielsen Hans Henrik Møller 1 , Thuesen Leif 1 , Andersen Henning Rud 1 , Hjortdal Vibeke E 1 ,<br />

Klaaborg Kaj-Erik 1 , Jakobsen Carl-Johan 1 , Böing Ingeborg 1<br />

1) Aarhus University Hospital, Skejby, Denmark<br />

Background<br />

Aortic valve stenosis is a common cause of morbidity and mortality among the elderly population. Medical treatment<br />

is often inadequate and most patients ultimately need aortic valve surgery (AVS). Up to one third of patients<br />

requiring AVS is deemed inoperable due to co-morbidities and consequently high risk. At Aarhus University Hospital,<br />

Skejby, catheter based stentvalve implantation have been used to treat selected highrisk patients with aortic valve<br />

stenosis since 2006.<br />

Aim<br />

The aim of this study was to evaluate morbidity and mortality following catheter based aortic valve implantation.<br />

Materials and methods: A total of 50 patients were treated with an aortic<br />

stentvalve between february 2008 and february <strong>2009</strong>. 15 were done via transfemoral (TFA-AVI) technique and<br />

35 via transapical technique (TAP-AVI). Median age of the patients was 83+ 6, 7 and 62% females. Mean logistic<br />

EUROscore was 19, 7% and 17, 5% in the TAP-AVI and TFA-AVI group respectively.<br />

Results<br />

Successful stent valve implantation were per<strong>for</strong>med in 46/50 (92%) patients. The first two patients in this series<br />

died during procedure TFA-AVI. There were no peroperative deaths in the TAP-AVI group. 30 days mortality rate<br />

was 20% in TFA-AVI and 6% in TAP-AVI group. There was no incidence of peroperative MI or coronary occlusion<br />

requiring PCI/CABG.<br />

Conclusion<br />

Catheter based aortic stent valve implantation is a feasible technique, requiring close co-operation between<br />

surgeons, cardiologists and anesthesiologists. The procedure should be reserved <strong>for</strong> selected highrisk patients<br />

deemed inoperable to conventional surgery, until further studies, preferably randomized trials, have documented<br />

the technique.<br />

STOCKHOLM, SWEDEN 39


S01:5<br />

THE NEW TNM STAGING SYSTEM FOR LUNG CANCER - A REVIEW OF 511 PATIENTS OPERATED AT<br />

KAROLINSKA UNIVERSITY HOSPITAL.<br />

Bergman Per 1 , Brodin Daniel 2 , De Petris Luigi 3<br />

1) Dept of Cardiothor Surgery and Anesthesiology, Karolinska, 2) Dept of Lung Medicine, Karolinska,<br />

3) KS Biomic Center, Karolinska Institutet, Sweden<br />

Objective<br />

In spite of diagnostical progress and more systematically lymph node dissection during lung cancer surgery, lung<br />

cancer is still the leading cause of cancer death in both sexes. It is a significant public health problem and has<br />

continuously increased in incidence and particulary in women with 3.6%/year <strong>for</strong> the last decade. The TNM staging<br />

system plays hereby a predominant role in the choice of treatment and <strong>for</strong> the prediction of the prognosis.<br />

Methods<br />

A comparison between the old staging system (sixth edit.) and the new staging system (seventh. edit.) was made<br />

among 511 patients operated <strong>for</strong> lung cancer at Karolinska during 1982-2002. Of particular interest was the median<br />

survival time (Kaplan Meier method) and the difference between the old subgroup IA (tumor size 3 cm) and the new<br />

subgroups IA-a ( 2 cm) and IA-b (>2 - 3 cm). The T-stage (tumor size) is in these groups a decisive factor.<br />

Results<br />

Comparing the old subgroup IA (91 month + 9.6) with the new subgroups IA-a and IA-b, there was a unexpected,<br />

significant difference between the median survival time comparing the new subgroups IA-a (110 month + 8,01)<br />

respectively IA-b (64 month + 6,1) indicating that patients with tumor size > 2 cm have a more severe prognosis<br />

than tumor sized 2 cm. Conclusion: The new staging system seems to better elucidate the prognostic importance of<br />

tumor size than the previous edition. These findings are also in accordance with several other published studies.<br />

S01:6<br />

NON-SELECTIVE CYCLOOXYGENASE (COX) INHIBITION DECREASES SHUNT DURING ONE-LUNG<br />

VENTILATION FOR THORACIC SURGERY.<br />

Rimeika Danguole 1 , Lindahl Sten G 1 , Wiklund Claes U 1<br />

1) Karolinska University Hospital, Sweden<br />

Background<br />

Prostacyclin has been shown to exert modulating effects on hypoxic pulmonary vasoconstriction (HPV). The<br />

purpose of this study was to investigate if cyclooxygenase inhibition decreases shunt fraction and improves arterial<br />

oxygenation during one-lung ventilation (OLV).<br />

Methods<br />

Altogether 32 patients exposed to OLV <strong>for</strong> thoracic surgery were randomly assigned to receive 75 mg diclofenac<br />

or saline intravenously after induction of anesthesia. Measurements were done during two-lung ventilation (TLV)<br />

in supine and lateral position, after 5, 15 and 30 minutes of OLV be<strong>for</strong>e surgical ligation of pulmonary vessels<br />

and finally after TLV was re-established.There were no differences between groups in patient characteristics or<br />

preoperative conditions. Cardiac index, mixed venous oxygen tension, PaCO2 and mean pulmonary arterial pressure<br />

were similar in the groups.<br />

Results<br />

In the placebo group the shunt fraction increased from 12 % during TLV to 37 % at 15 minutes of OLV and 38 %<br />

at 30 minutes of OLV. In the diclofenac treated group shunt fraction increased from 12 % at TLV to 27 % after 15<br />

minutes of OLV and to 29 % at 30 minutes of OLV. Shunt fraction was significantly improved in the diclofenac group<br />

compared with the placebo group, at 15 minutes of OLV (P = 0.043). Conclusion: It was concluded that COXinhibition<br />

with diclofenac augments hypoxic pulmonary vasoconstriction and decreases shunt fraction during OLV<br />

<strong>for</strong> thoracic surgery.<br />

40 www.sats<strong>2009</strong>.org


S03<br />

SATNU ORAL ABSTRACT SESSION<br />

THEME: DEALING WITH PATIENTS’ PHYSICAL POSTOPERATIVE PROBLEMS<br />

S03:1<br />

POSTOPERATIVE NAUSEA AND VOMITING AFTER CARDIAC SURGERY: NURSING POINT OF VIEW<br />

Murkka Timo 1 , Niemi Anu 1 , Järvelä Kati 1 , Maaranen Pasi 1 , Huhtala Heini 2 , Sisto Tero 1 ,<br />

1) Heartcenter/ Pirkanmaa hospital district, 2) Tampere University, Finland<br />

Introduction<br />

Postoperative nausea and vomiting (PONV) is a very distressing adverse event. In this study, we tested the use of<br />

Apfel-score in predicting PONV among male cardiac surgery patients. This score consists of four predictors: female<br />

gender, history of motion sickness or PONV, nonsmoking, and the use of postoperative opioids. We also evaluated<br />

how harmful the patients and the nurses experienced PONV after coronary artery bypass grafting (CABG).<br />

Methods<br />

Fifty men undergoing CABG were interviewed preoperatively. PONV was treated according to a protocol. The<br />

patients were interviewed at the end of ICU stay and on the ward 2-5 days later. The ICU nurses answered a<br />

question: Is PONV a nursing problem in these patients?<br />

Results<br />

Total incidence of PONV was 34.7%. The measured incidences of PONV <strong>for</strong> Apfel-scores 1, 2 and 3 were 22, 41 and<br />

67% while the predicted incidences were 21, 39 and 61%. One third of the patients (32%) did not remember their<br />

ICU stay at all. Only one patient (2%) experienced insufficient treatment <strong>for</strong> PONV. Most of the ICU nurses (88.2%)<br />

did not consider PONV as a nursing problem in our ICU.<br />

Discussion<br />

Apfel-score predicted PONV very well in male cardiac surgery patients. PONV is common in this patient group, but<br />

the ICU nurses did not find it problematic, because they have sufficient tools to treat the patients. The patients were<br />

also satisfied. There<strong>for</strong>e, we are now using even more aggressive treatment protocol.<br />

S03:2<br />

PREDICTION OF THE CONSUMPTION OF OPIOID ANALGESICS FOLLOWING MINIMALLY INVASIVE<br />

CORRECTION OF PECTUS EXCAVATUM<br />

Grosen Kasper 1 , Pilegaard Hans K. 2 , Jensen Mogens P. 3<br />

1) Aarhus University, 2) Aarhus University Hospital, Skejby, 3) Aarhus University Hospital, NBG, Denmark<br />

Background<br />

Minimally invasive correction of pectus excavatum (MIRPE) is primarily per<strong>for</strong>med to obtain cosmetic and<br />

psychological benefits <strong>for</strong> the patient. MIRPE is often associated with postoperative pain management problems.<br />

This study estimates the effect of the severity of pectus excavatum on the postoperative consumption of opioid<br />

analgesics following the minimally invasive procedure in order to optimize pain management.<br />

Methods<br />

A retrospective study was conducted on 236 consecutive patients undergoing MIRPE from 2005-2008. The collected<br />

data included evaluation of preoperative pectus excavation depth, patient demographics, data <strong>for</strong> the peri- and<br />

postoperative period, including data on the pain management. The consumption of opioid analgesics was registered<br />

after discontinuation of epidural analgesia and the various types of opioid analgesics used during the study period<br />

were converted to morphine equivalents.<br />

Results<br />

The total morphine consumption following MIRPE ranged between 20 and 370 mg/day. Multiple linear regression<br />

analysis explained approx. 30% of the variation in log(morphine, mg/day) (R2=0.2957). There was a significant positive<br />

linear relationship between pectus severity and daily consumtion of morphine. Thus, postoperative consumption of<br />

morphine increased by 6% (95% CI: 0.3 to 11%) when preoperative pectus excavatum depth deteriorated with 1 cm.<br />

Conclusion<br />

This study confirms that pectus severity plays a significant role <strong>for</strong> the consumption of opioid analgesics<br />

following MIRPE. We conclude that knowledge of pectus severity might be useful in the prediction of the<br />

expected morphine consumption <strong>for</strong> future patients, especially in the critical transition period going from<br />

epidural analgesia to oral analgesia.<br />

STOCKHOLM, SWEDEN 41


S03:3<br />

GABAPENTIN FOR POSTOPERATIVE PAIN MANAGEMENT AFTER CARDIAC SURGERY WITH MEDIAN<br />

STERNOTOMY<br />

Laursen Vibeke 1 , Tang Mariann 2 , Parvaiz Imran 3 , Hjortdal Vibeke 2<br />

1) Aarhus University Hospital, Skejby, 2) Department of Cardiothoracic Surgery,SKS,<br />

3) Department of Cardiacthoracic Surgery,RH, Denmark<br />

Introduction<br />

Cardiac surgery with sternotomy is a major surgical trauma. The surgical injury and anaestesia is followed by pain,<br />

postoperative nausea and vomiting (PONV). Pain relief after surgery is prerequisite <strong>for</strong> moblisation and early return<br />

to pre-surgical level. The preferred drug <strong>for</strong> postoperative pain management is opioids which are known to have<br />

a series of side effects such as nausea, vomiting, constipation and delirium. More than one third of the patients<br />

experience PONV after cardiac surgery. PONV is associated with longer stay in post-anaesthesia care and may<br />

cause dehydration and prolonged recovery. Gabapentin was originally developed to treat spasticity but during the<br />

last decade more publications and reports have documented pain relief with use of Gabapentin. Hence no studies<br />

have evaluated Gabapentin as postoperative pain management after cardiac surgery.<br />

Aim/hypothesis<br />

To examine the effect of Gabapentin on postoperative pain after cardiac surgery with the hypothesis being that<br />

Gabapentin is an effective analgesic <strong>for</strong> postoperative pain and has a opioid sparing effect.<br />

Materials & Methods<br />

A clinical randomized, controlled and double blind study including 64 patients scheduled <strong>for</strong> cardiac surgery with<br />

median sternotomy. Patients were randomized to either placebo or gabapentin. The dosage of gabapentin was 1200<br />

mg on the day of surgery and 300 mg twice a day <strong>for</strong> the following five days. Four times a day the patients did pain<br />

assessment with Visual Analogue Score and PONV assessment.<br />

Results<br />

Data are being processed.<br />

S03:4<br />

THE EFFECT OF SOOTHING MUSIC IN RESPONSE TO STRESS AND RELAXATION DURING BED REST<br />

AFTER OPEN-HEART SURGERY<br />

Nilsson Ulrica 1<br />

1) Centre of Health Care Sciences, Sweden<br />

Music interventions have been evaluated as an appropriate intervention to reduce pain, stress and anxiety in<br />

a number of clinical settings. A new challenge is to study if music also can influence relaxation system that<br />

incorporates oxytocin.<br />

Aim<br />

To evaluate the effect of bed rest with music on stress and relaxation <strong>for</strong> patients who had undergone heart surgery<br />

on postoperative day one.<br />

Method<br />

Fifty-eight patients who had randomly allocated to either music listening during bed rest or bed rest only. The music<br />

was distributed through a music pillow connected to a MP3 player and the music, MusiCure, was soft, relaxing, and<br />

included different melodies of 60 to 80 bpm and was played <strong>for</strong> 30 minutes with a volume of 50-60 dB. Stress and<br />

relaxation response was assessed by s-cortisol, s-oxytocin, heart rate, respiratory rate, MAP, PaO2 , SaO2 and<br />

subjective pain, anxiety and relaxation levels. Results: In the music group levels of oxytocin increased significantly in<br />

contrast to the control group <strong>for</strong> which the trend over time was negative i.e. decreasing values. Subjective relaxation<br />

levels increased significantly more and there were also a significant higher levels of PaO2. After 30 minutes there<br />

was a significantly less s-cortisol levels in the music group. There was no difference in MAP, heart rate and SaO2<br />

between the groups.<br />

Conclusion<br />

Music intervention should bee used as an integral part of the multimodal regime administered to the patients that<br />

have undergone cardiovascular surgery.<br />

42 www.sats<strong>2009</strong>.org


S03:5<br />

NURSEMANAGED INSULIN PROTOCOL IMPROVES TREATMENT OF HYPERGLYCAEMIA IN PATIENTS<br />

WITH DIABETES UNDERGOING OPEN HEART SURGERY<br />

Lange Aase 1<br />

1) Aarhus University Hospital Skejby, Denmark<br />

Background<br />

Strict glycemic control in critically ill patients is challeging <strong>for</strong> both nurses and physicians. Studies Have shown<br />

that aggressive glycemic control by a nursemanaged subcutaneous insulin protocol outside ICU improves mortality<br />

and morbidity as well as efficiency and safety. An audit made in 2006 at the Department of Cardiothoratic<br />

Surgery at Aarhus University Hospital Skejby, Denmark showed that only 62 % of patients with hyperglycemia<br />

were treated according to recommendations. The low compliance was presumably due to fear of hypoglycaemia<br />

and lack of knowledge.<br />

Objectives<br />

To determine the effect of focused education of nurses followed by implementation of a nursemanaged insulin protocol.<br />

Methods<br />

Intensive education of nurses followed by development and implementation of a nursemanaged insulin protocol. Two<br />

audits to determine if hyperglycaemia was treated according to the implemented insulin protocol. Blood glucose<br />

levels and insulin doses per day were documented in 15 patients be<strong>for</strong>e and in 15 patients after implementation of<br />

the protocol.<br />

Results<br />

Audit in 2006: number of measured hyperglycaemia values in 15 patients was 105 and 62 % were treated according<br />

to reccommendations. Audit in <strong>2009</strong>: number of measured hyperglycaemia values in 15 patients after implementation<br />

of insulin protocol was 263 and 90,5 % were treated according to the nursemanaged insulin protocol.<br />

Conclusions<br />

Intensive education followed by development and implementation of a nursemanaged insulin protocol has increadsed<br />

compliance and led to a considerable improvement in the treatment of hyperglycaemia. Potentially this could lead to<br />

improved mortality and morbidity <strong>for</strong> this patientgroup.<br />

S03:6<br />

PREVALANCE OF POSTOPERATIVE PROBLEMS AMONG DANISH HEART-OPERATED PATIENTS<br />

14 DAYS AFTER DISCHARGE FROM HOSPITAL<br />

Ibsen Dorthe 1 , Greve Helle 1<br />

1) Rigshospitalet, Denmark<br />

Background<br />

Several patients call the heart-surgery ward because they don’t know where to address problems related to dyspnoea,<br />

medication, and infections. International research documents that many heart-operated patients experience<br />

emotional and physiological problems one year after their operation. The aim of this study is to gain knowledge<br />

about Danish heart-operated patients´ experience of these problems during the first 14 days after discharge from<br />

hospital, to uncover if the constructed questionnaire is useful to gain in<strong>for</strong>mation about this, and as background <strong>for</strong><br />

a clarifying telephone interview.<br />

Method<br />

Data was acquired by use of a semistructured questionnaire, followed up by telephone-interviews. 9 patients were<br />

asked to complete the questionnaire, and to participate in the interview 14 days after discharge. The results are<br />

preliminary as the study is not yet completed. 8 patients participated in the study, 6 males and 2 females, age<br />

between 50-72 years. 6/8 experienced depression in the first 7-14 days, 7/8 pain, 6/8 sleeping problems, 6/8 lack<br />

of energy.<br />

Conclusions<br />

Danish heart surgery patients seem to have the same emotional and physiological problems during the first 14 days<br />

after discharge, as shown in international research. The semistructured questionnaire and telephone interviews<br />

<strong>for</strong>med a basis <strong>for</strong> gaining knowledge of patients’ problems during the first 14 days at home. According to the<br />

preliminary results it seems important that nurses call their patients after discharge, and individualize the discharge<br />

dialogue to make sure that patients are more capable to act adequate upon the challenges, experienced after their<br />

discharge from hospital.<br />

STOCKHOLM, SWEDEN 43


S05<br />

<strong>SATS</strong> CARDIAC ORAL ABSTRACT SESSION<br />

S05:1<br />

INITIAL EXPERIENCE WITH A CATHETER BASED AORTIC VALVE IMPLANTATION SYSTEM.<br />

Ahn Henrik 1 , Baranowski Jacek 1 , Freter Wolfgang 1 , Nielsen Niels Erik 1 , Nylander Eva 1 , Wallby Lars 1 , Tamas Eva 1<br />

1) Linköping Heart Center, Sweden<br />

Fifteen patients (pts), 9 females and 6 males, mean age 78 (60-91) years were selected <strong>for</strong> transcatheter aortic<br />

valve implantation. The pts were evaluated according to our regular routines and denied <strong>for</strong> open chest surgery<br />

due to high risk profile with logistic Euroscore 22 (7-45) % and STS score 19 (10-30). Mean maximal velocity<br />

(Vmax) was 4.8 (3.8–6.5) m/s, the mean gradient was 60 (33-108) mmHg and the mean aortic valve area was<br />

0.5 (0.4–0.8) cm2.<br />

Methods<br />

All procedures were carried out in general anesthesia using the Sapien valve (Edwards Lifesciences). Ten transapical<br />

and 5 transfemoral implants were per<strong>for</strong>med.<br />

Results<br />

All implantations (8 valves 26 mm and 7 valves 23 mm) were successful. Blood pressure failed to recover in 2<br />

pts following rapid pacing necessitating CPR with good recovery. However, 2 pts suffered from renal failure, one<br />

needing dialysis.<br />

One pt got a postoperative pericardial effusion. The 30-day mortality was 1/15 pts as well as the 90-day mortality.<br />

The residual aortic valve leaks (central and paravalvular) were small in all pts. Post-implant mean Vmax was 2.4<br />

(1.5–2.9) m/s and the mean gradient was 15 (4-37) mmHg. The mean ICU-stay was 2.6 (1-18) days. Pts were<br />

discharged after 10 (4-18) days.<br />

Conclusion<br />

This new technology worked well in our hands and the procedure was per<strong>for</strong>med with reproducible and acceptable<br />

results. The patient selection is a challenge since serious comorbidity can impair results, disguising the potential of<br />

this promising technology. The long-term results will be the most important endpoints.<br />

S05:2<br />

ECHO-GUIDED PRESENTATION OF AORTIC VALVE MINIMISES CONTRAST MEDIUM EXPOSURE IN<br />

SAPIEN AORTIC VALVE RECIPIENTS.<br />

Baranowski Jacek 1 , Ahn Henrik 1 , Freter Wolfgang 1 , Nielsen Niels Erik 1 , Nylander Eva 1 , Tamas Eva 1 , Wallby Lars 1<br />

1) Linköping Heart Center, Sweden<br />

During Sapien aortic valve prothesis implantation a perpendicular position of the aortic valve to the radiation beam<br />

is a sine-qua-non <strong>for</strong> the optimal prosthesis delivery. This right valve-beam-angle is expected to lower risks <strong>for</strong><br />

proximal and distal embolisation of the protheses, reststenosis, coronary artery occlusion, and AV-block occurrence.<br />

The current gold standard to achieve this optimal angle is to use repeated aortic aortograms. The Sapien valve<br />

candidates often have reduced renal function with contrast exposure being an important factor <strong>for</strong> their recovery.<br />

Material and methods<br />

Transcatheter Sapien aortic valve prostheses have been implanted in 15 patients. Various methods <strong>for</strong> perpendicular<br />

valve presentation during fluoroscopy were employed: statistical chance, CT, repeated ascendens aortograms and<br />

transthoracic echo-guided presentation in a new Linköping design.<br />

Results<br />

Statistical chance and CT have failed to be of help during the procedure. Repeated ascendens aortograms make<br />

the procedure feasible with the price of high contrast volumes and long fluoroscopy times. The transthoracic echoguided<br />

presentation resulted in a dramatic decrease in contrast ( from 223 ml/ procedure to 69 ml/procedure) and<br />

some in radiation exposure to the patients during the procedure.<br />

Conclusion<br />

Our echo-guided method <strong>for</strong> perpendicular aortic valve position lowers significantly the contrast media exposure in<br />

the fragile population of transcatheter aortic prosthesis recipients.<br />

44 www.sats<strong>2009</strong>.org


S05:3<br />

SURVIVAL AND QUALITY OF LIFE AFTER AORTIC ROOT REPLACEMENT WITH CRYOPRESERVED<br />

HOMOGRAFTS IN ACUTE ENDOCARDITIS<br />

Perrotta Sossio 1 , Aljassim Obaid 1 , Bech-hanssen Odd 1 , Jeppsson Anders 1 , Svensson Gunnar 1<br />

1) Sahlgrenska University Hospital, Sweden<br />

Background<br />

Aortic root replacement with homograft is a theoretically attractive but technically demanding option in patients with<br />

infective endocarditis, especially in patients with subvalvular abscesses and/or prosthetic endocarditis. We report<br />

our midterm experience with cryopreserved homografts in acute infective aortic endocarditis.<br />

Methods<br />

All 62 patients operated with aortic homograft <strong>for</strong> severe acute aortic endocarditis between 1997 and June 2008 were<br />

retrospectively analysed. Fifty two (84%) had subvalvular abscesses. 24 patients (39%) had prosthetic endocarditis.<br />

Survival, perioperative complications, re-operations and quality of life (SF 36) were assessed. Mean follow-up was<br />

3.1 years (range 0 12).<br />

Results<br />

Nine patients (14%) died within 30 days. Pre and perioperative variables univariately associated with early<br />

mortality were CPB-time (p=0.003), prolonged inotropic support (p=0.03), reoperation <strong>for</strong> bleeding (p=0.01) and<br />

perioperative myocardial infarction (p


S05:5<br />

MINIMALLY INVASIVE REOPERATIVE AORTIC VALVE SURGERY WITH PATENT CORONARY ARTERY<br />

BYPASS GRAFTS<br />

Raffa Giuseppe 1 , Pellegrini Carlo 2 , Savasta Marcello 2 , Pozzi Matteo 2 , Vigano’ Mario 2<br />

1) The Salam Centre <strong>for</strong> Cardiac Surgery, Sudan 2) University of Pavia, Italy<br />

Objective<br />

Cardiac reoperations are associated with higher morbidity and mortality mainly due to the risk of damaging cardiac<br />

structures. Minimally invasive techniques may reduce the surgical risks.<br />

Methods<br />

Since 1997, more than 1000 mini-sternotomies have been per<strong>for</strong>med at our department. Out of these, seventeen<br />

patients (15 males, 2 females, mean age: 68.7 years) had a patent graft on LAD. Mean ejection fraction was<br />

45% and NYHA class 2.7. Fifteen patients underwent native aortic valve replacement, whereas in two patients a<br />

malfunctioning valve prosthesis was replaced.<br />

Results<br />

Mean cardiopulmonary and aortic cross clamp time were 119.7±38.1 (range: 50-235) and 72±20 (range: 45-125)<br />

minutes, respectively. Mean cooling body temperature was 27.4 (°C). Antegrade cold crystalloid cardioplegia was<br />

delivered to all the patients. LIMA injury occurred in one patient and caused perioperative myocardial infarction,<br />

low cardiac output syndrome requiring intraaortic balloon pump and, eventually, hospital death (5.9%). Neither<br />

conversion to full sternotomy nor reoperation <strong>for</strong> bleeding occurred. Mean bleeding was 426±474 ml (range: 120-<br />

1950). Mean postoperative ICU and hospital stay were 1.6±1.1 and 7.5±2.6 days, respectively. Postoperative<br />

course was totally uneventful in ten patients (58.8%). Follow-up was complete <strong>for</strong> a total of 928 patient/months<br />

(range: 11-124): four late deaths occurred, two related to cardiac causes. Prosthesis related morbidity did not occur<br />

either early or late. Nine of the 12 survivors (75 %) are in NYHA class II.<br />

Conclusions<br />

Considering the low complication rate, a minimally invasive access in the presence of patent coronary artery grafts<br />

may represent a preferential surgical approach.<br />

S05:6<br />

HYPOTHYROIDISM IN CARDIAC SURGERY PATIENTS. A SINGLE UNIT FOLLOW-UP.<br />

Jyrala Aarne 1 , Kay Gregory L 1<br />

1) United States<br />

The aim of this study is to analyze patient presentation, early and late outcomes in patients with hypothyroidism (HT)<br />

compared to patients matched by age, gender and type of surgery.<br />

Of 1000 consecutive cardiac surgery patients operated between Jan 1999 and May 2000 80 pts had a diagnosis of<br />

HT (Group 1); 80 matched pts were identified from the database (Group 2).<br />

Additive EuroSCORE (ES) did not differ between the groups but logistic ES did (p=0.05). The proportion of very<br />

high-risk pts (log ES >25%) was higher in Group 1 (24.1% vs 17.7%), more pts had CHF (43.8%vs36.3%), had<br />

diabetes (43.8%vs35.0%), were in NYHA class III-IV (66.4%-55.0%) or had AF (16.5% vs 0 %).<br />

There were no operative deaths. Hospital mortality was similar. New AF occurred in 23.0 % of pts in Group 1 and in<br />

9.2% in Group 2. There were more pts in Group 1 with prolonged hospital stay (>10 days, 28.4% vs 18.3%) and 4<br />

times more pts in Group 1 needed extended care or rehabilitation after discharge. All-cause follow-up mortality (up<br />

to 107 months) was higher in Group 1 (43.0% vs 30.4%). 2 pts died in the postoperative period due to untreated HT.<br />

All comparisons have p-value 0.05 or lower.<br />

Conclusions<br />

HT pts are sicker at presentation than controls, their resource utilization is higher and survival lower. Occurrence of<br />

postoperative AF is considerably higher. Although there were no operative deaths and hospital mortality was similar,<br />

postoperative deaths occurred when HT was not adequately treated.<br />

46 www.sats<strong>2009</strong>.org


S05:7<br />

CONTINUOUS VENOVENOUS HEMODIALYSIS (CVVHD) WITH CITRATE CALCIUM REDUCES<br />

POSTOPERATIVE BLEEDING COMPLICATIONS AFTER CARDIAC SURGERY<br />

Kiessling Arndt-h. 1 , Neher Michael 1 , Kornberger Angela 1 , Lehmann Andreas 1 , Raoul Bergner 1 ,<br />

Isgro Frank 1 , Saggau Werner 1<br />

1) Klinikum Ludwigshafen, Germany<br />

Objective<br />

Continuous renal replacement therapy is the preferred method of treatment of acute renal failure after cardiac<br />

surgery. Efficient anticoagulation of the extracorporeal circulation is essential to prevent clotting of the system.<br />

Regional anticoagulation using citrate is assumed to reduce the risk of systemic bleeding. The present study<br />

investigates the safety of citrate dialysis (CI-CA) after cardiac surgery in comparison with conventional procedures<br />

using heparin (HEP).<br />

Methods<br />

In a prospective randomized, non-blinded monocentric trial (11/2008-02/<strong>2009</strong>), we compared continuous venovenous<br />

hemodialysis (CVVHD) using heparin (Diapact CRRT B.Braun AG, Germany) (n=26) against a citrate calcium<br />

method (Ci-Ca multifiltrate Fresenius Medical Care, Germany) (n =24). In the HEP group, the system was primed<br />

with 600 IE heparin and run with a minimum of 15000IE/24h of heparin on the basis of HEP test controls (0.4-0.7).<br />

Our primary end points were bleeding events, death, cardiac arrhythmia, creatinine levels and filter occlusion.<br />

Results<br />

There were no differences between the demographic data of the patient groups and no significant difference as<br />

far as the surgical procedures per<strong>for</strong>med and postoperative catecholamine support are concerned. The incidence<br />

of bleeding was significant higher in the HEP group. No differences were found <strong>for</strong> the items: mortality, ICU stay,<br />

respirator time and arrhythmias.<br />

Conclusion<br />

CiCA proved effective and safe. A significant prolongation of filter patency was noted. A significant difference in<br />

mortality was not registered within the small study population. Changes of plasmatic calcium levels representing a<br />

potential risk of cardiac arrhythmia or cardiac output reduction did not occur.<br />

STOCKHOLM, SWEDEN 47


S06<br />

SCANSECT ORAL ABSTRACT SESSION<br />

S06:1<br />

FIBRINOGEN AND THE ACUTE INFLAMMATORY RESPONSE AFTER CARDIAC SURGERY<br />

Kalabic Maria 1 , Jeppsson Anders 1 , Rexius Helena 1<br />

1) Sahlgrenska University Hospital, Sweden<br />

Objective<br />

Fibrinogen concentrate can be used to prevent or treat bleeding after cardiac surgery but it may also raise plasma<br />

concentrations to supra-normal levels, potentially leading to hypercoagulability. Fibrinogen is an acute phase reactant<br />

and plasma concentration increases in response to the surgical trauma. The aim of the study was to establish the<br />

normal response of fibrinogen to cardiac surgery and its potential association to other acute phase reactants.<br />

Methods<br />

Fifteen on-pump CABG patients were included in a prospective observational study. Plasma concentrations of<br />

fibrinogen, C-reactive protein (CRP) and interleukin-6 (IL-6) were measured be<strong>for</strong>e surgery (baseline) and day 1 to<br />

day 4 after surgery. Plasma concentrations at the different time points were compared to baseline and correlation<br />

calculations between fibrinogen, CRP and IL-6 were per<strong>for</strong>med.<br />

Results<br />

Fibrinogen plasma concentration increased during the study period from 3.9±0.6 to 7.8±1.9 g/L (p


S06:2<br />

PLATELET AGGREGABILITY BEFORE AND AFTER CORONARY ARTERY BYPASS SURGERY<br />

Önsten Linda 1 , Jeppsson Anders 1 , Rexius Helena 1<br />

1) Sahlgrenska University Hospital, Sweden<br />

Objective<br />

Platelet dysfunction may contribute to bleeding complications after Coronary artery bypass grafting (CABG).<br />

Impedance aggregometry is a new point-of-care method to assess platelet function. We determined platelet<br />

impedance aggregation be<strong>for</strong>e and after CABG surgery.<br />

Methods<br />

10 patients treated with aspirin and adenosine-diphosphate (ADP) receptor blocker clopidogrel and 9 patients treated<br />

with aspirin within 7 days be<strong>for</strong>e surgery were included in this prospective observational study. Platelet aggregation<br />

was compared between individual time points and between patients with or without clopidogrel treatment. Impedance<br />

aggregometry (Multiplate�), with ADP and thrombin receptor activated peptide 6 (TRAP) as activators.<br />

Results<br />

ADP-induced platelet aggregation at sternum closure was reduced compared to the day be<strong>for</strong>e surgery, to anesthesia<br />

induction and to the day after surgery (20±15 units vs. 41±24, 36±17 and 43±18, respectively (p


S06:4<br />

IN VITRO COMPARISON OF THE NEW IN-LINE MONITOR BMU 40 VS. THE CONVENTIONAL<br />

LABORATORY ANALYSER ABL 700<br />

Grosse F. Oliver 1 , Holzhey David 2 , Falk Volkmar 2 , Schaarschmidt Jan 1 , Kraemer Klaus 1 , Mohr Friedrich Wilhelm 1<br />

1) University of Leipzig - Heart Center, Germany 2) University Hospital, Zurich, Switzerland<br />

Background<br />

Reliable in<strong>for</strong>mation about different blood parameters is essential maintaining haemodynamics, perfusion and gas<br />

exchange during CPB. For this purpose a precise and continuous monitoring is needed. The objective of this in vitro<br />

study was to compare a novel continuous in-line blood parameter monitoring system (CIBPMS) vs. a reference<br />

laboratory analyser.<br />

Methods<br />

The study was conducted as an in vitro prospective experimental study during a CPB simulation. The reliability of<br />

BMU 40 was tested in monitoring the pO2, SO2 and Hct under physiological and extreme conditions with regards<br />

to temperature, oxygenation and blood concentration. Four different tests were per<strong>for</strong>med and conducted with five<br />

sensors each. Correlation analyses and Bland-Altman analyses were per<strong>for</strong>med.<br />

Results<br />

A total of 350 measurement points were compared. All monitored values of blood parameters correlated highly with<br />

laboratory values (all r values > 0.90). Test 1: Biases of pO2(act) vary from -3.24 (±6.86) up to 6.0 (±17.89). The<br />

biases of pO2(37°C) ranged from -3.08 (±5.53) up to 68.8 (±67.82). Test 2: The biases (SD) <strong>for</strong> Hct ranged from<br />

-0.35 (±0.79) up to 2.35 (±0.91). The biases (SD) <strong>for</strong> SO2 vary from -0.45 (±0.86) up to 0.85 (±1.01). Test 3: The<br />

biases (SD) of Hct ranged from -0.67 (±1.49) up to -1.00 (±1.84). Test 4: The biases (SD) <strong>for</strong> SO2 vary from -0.36<br />

(±1.60) up to 0.48 (±0.90).<br />

Conclusions<br />

The BMU 40 is a reliable device in measuring the pO2, SO2 and Hct under normal physiological and extreme<br />

conditions with regards to temperature, oxygenation and blood concentration in simulation of CPB. The algorithm to<br />

calculate pO2(37°) under hypothermic conditions need to be adjusted.*<br />

*In the meantime a new software version of the BMU 40 has been developed. The algorithm to calculate pO2(37°)<br />

under hypothermic conditions has been improved and the miscalculation eliminated.<br />

S06:5<br />

CLINICAL EVALUATION OF THE NEW BMU 40 IN-LINE BLOOD ANALYSIS MONITOR<br />

Schaarschmidt Jan 1 , Borger Michael Andrew 1 , Seeburger Joerg 1 , Grosse Frank Oliver 1 ,<br />

Kraemer Klaus 1 , Mohr Friedrich Wilhelm 1<br />

1) University of Leipzig, Heart Center, Germany<br />

Background<br />

Accurate in<strong>for</strong>mation about different blood parameters is essential in maintaining haemodynamics, perfusion and<br />

gas exchange during cardiopulmonary bypass (CPB). For this purpose a precise and continuous measurement and<br />

monitoring, which is preferably visually available, is needed. The objective of this clinical study was to compare<br />

the newly developed continuous in-line blood parameter monitoring system (CIBPMS) BMU 40, based on optical<br />

luminescence and reflectance technology, with a reference laboratory analyser with regards to the precision of blood<br />

parameters measurement.<br />

Methods<br />

Thirty adult patients underwent elective cardiac surgery utilizing CPB and mild hypothermia (32°C). At five<br />

predetermined time points (S1 – S5) arterial and venous blood samples were analysed using the BMU 40 <strong>for</strong> five<br />

different parameters (paO2(37°C), paO2(act.), SvO2, Hb(ven) and Hct(ven)) and these results were compared to<br />

the gold standard laboratory analyser ABL 700.<br />

Results<br />

A total of 150 paired blood samples were included to compare means, to analyse correlation, to calculate measures<br />

of bias, precision, limits of agreement and 95% confidence intervals. Results revealed good agreement between the<br />

two devices <strong>for</strong> all parameters. Bias ± precision of S2 – S5 paO2(37°C) were 2.17 ± 9.61; paO2(act) 2.58 ± 9.54;<br />

SvO2 -1.44 ± 2.35; Hb(ven) 0.01 ± 0.42; Hct(ven) 0.04 ± 1.29. Statistically significant differences were detected<br />

<strong>for</strong> SvO2 (p


S06:6<br />

ECMO - THE ICELANDIC EXPERIENCE<br />

Astradsson Thorsteinn 1 , Torfason Bjarni 1 , Gudbjartsson Tomas 1 , Simonardottir Liney 1 , Valsson Felix 1<br />

1) Landspitali University Hospital, Iceland<br />

Background<br />

Extracorporeal membrane oxygenation (ECMO) can prove lifesaving in severe respiratory failure (ARDS) and<br />

cardiac failure (CF) refractory to conventional treatment. Because of the complicity and potential complications,<br />

ECMO treatment has been limited to larger medical centers.<br />

Aim<br />

This study evaluates ECMO treatment in Iceland a small and relatively isolated community.<br />

Results<br />

18 patients have been treated with ECMO in Iceland from 1991. Nine of those had ARDS while the other 9 had<br />

CF. Survival rate was 56% <strong>for</strong> both groups, the mean age of ARDS survivors was 20 compared to 50 years <strong>for</strong><br />

non-survivors while the mean age of CF survivors was 33 vs 49 years <strong>for</strong> the non-survivors. Mean pre-ECMO<br />

ventilator time <strong>for</strong> ARDS survivors was 5,2 days (0,5-18) compared to 9,8 days (1-14) <strong>for</strong> ARDS non-survivors. One<br />

of four ARDS patients with a pre-ECMO ventilator time longer than 7 days survived and four of five patient with<br />

pre-ECMO ventilator time less than 7 days survived. CF survivors had lower APACHE II scores than non-surviving<br />

CF patients (14 vs 32). One patient died from hemorrhage related to anticoagulation, while three other patients<br />

survived significant hemorrhage. Recombinant factor VIIa was given to two patients both of which survived. All other<br />

non-survivors succumbed to their underlying diseases.<br />

Discussion<br />

Survival rates (56%) in Iceland are similar to those seen in recent publications. No age limit or pre-ECMO ventilator<br />

time limit has been implemented in Iceland. A stricter protocol regarding age and pre-ECMO ventilator time will be<br />

en<strong>for</strong>ced in future ECMO candidates in Iceland.<br />

S06:7<br />

EXTRACORPOREAL MEMBRANE OXYGENATION SUPPORT FOR 59 DAYS WITHOUT CHANGING THE<br />

ECMO CIRCUIT<br />

Thiara Amrit Singh 1 , Høyland Vivian 1 , Norum Hilde 1 , Aasmundstad Tor 1 , Karlsen Harald 1 , Fiane Arnt 1 , Geiran Odd 1<br />

1) Rikshospitalet, Norway<br />

Background<br />

Veno-venous extracorporeal membrane oxygenation is an established support <strong>for</strong> the treatment of respiratory<br />

failure. We report the successful use of veno-venous ECMO in a 53 year old patient with Legionella pneumonia and<br />

acute respiratory distress syndrome (ARDS) with severe barotraumas.<br />

He was admitted to intensive care unit. His clinical course deteriorated, despite the continuous support with<br />

mechanical ventilation.<br />

Interventions<br />

He was placed on veno-venous ECMO <strong>for</strong> lung rest and while awaiting a response to continued medical treatment.<br />

He was supported by ECMO <strong>for</strong> 59 days without any changes in the ECMO circuit. There were no complications<br />

with the ECMO circuit during the support period.<br />

Conclusion<br />

ECMO can provide a chance of survival even in severe case of ARDS. This is likely the longest support ever reported<br />

using the same oxygenator.<br />

STOCKHOLM, SWEDEN 51


S06:8<br />

COAGULATION IN OXYGENATOR AND ARTERIAL FILTER AFTER RECIRCULATION<br />

Bellaiche Anne Louise 1 , Nielsen Peter Fast 1 , Sprogøe Pia 1 , Klungreseth Oddvar 1<br />

1) Aarhus University Hospital Skejby, Denmark<br />

We report a case of multiple coagulation in two successive oxygenators and one arterial filter when restarting<br />

bypass after 3 hours of recirculation. The case involves emergency surgery <strong>for</strong> dissection of the aorta with insertion<br />

of a homograft using 18 min. of deep hypothermic circulatory arrest and 4 hours of CPB. Bypass is terminated and<br />

protamin administered. Over the following three hours the bypass circuit is circulating while remaining bleeding<br />

is seeked managed surgically and with blood products, cryoprecipitate, haemocompletan and NovoSeven. Going<br />

back on bypass, clots are observed in the oxygenator which is replaced. After initiation of the second bypass period<br />

the arterial filter also shows clotting and is replaced. There is persistent high pressure in the whole circuit,- but<br />

no other clots could be determined at this point. After 1½ hours of bypass, shortly be<strong>for</strong>e weaning, new clots are<br />

observed in the second oxygenator. Bypass is terminated shortly after without problems. ACTs levels measured at<br />

half-hour intervals during the two bypass periods were all above the lower limit (400 sec. measured by Hemochron<br />

Jr) according to our protocol. Two days post-operatively the patient developed dilated pupils. CT scan shows brain<br />

infarction and the patient passed away the next day. Autopsy was not per<strong>for</strong>med. Clots from the circuit could be a<br />

possible cause of the brain damage, however, other explanations are also possible. We present this case <strong>for</strong> peer<br />

discussion with the aim of avoiding similar incidents in the future.<br />

52 www.sats<strong>2009</strong>.org


S07<br />

SATNU ORAL ABSTRACT SESSION<br />

S07:1<br />

HOW DOES NURSING COMPETENCE EXPRESS ITSELF IN THE OPERATING ROOM ?<br />

Walsoe Charlotte 1<br />

1) The Heart Centre, Rigshospitalet, Denmark<br />

An ongoing shortage of nurses in the operating room and generel recruitment difficulties challenges the Danish<br />

health system. As the shortage will continue in the years to come, politicians question the neccesity of exclusively<br />

nurses in the operating room and want to solve the situation by employing staff with a different education. The<br />

operating room nurses have no tradition documenting the essence and quality of nursing, and consequently now<br />

stand with a serious challenge in the discussion of the importance of nurses and nursing in the operating room.<br />

A study was conducted with the question “How does nursing competence and quality express itself in the operating<br />

room? ”.<br />

A search in CINAHL, PubMed and SweMed+ using the terms “nursing and operating room” resulted in 8 qualified<br />

articles, which have been used in this study.<br />

Patricia Benner was used in the theoretical analysis of the articles regarding the competence and essence of nursing<br />

in the operating room.<br />

Theories of the patients’ course of stay in hospital and quality control were used in the study.<br />

The nursing competence express itself in:<br />

- Caring - caring and technology are combined inseparable partners.<br />

- Congruity and continuity during the patients’ course of stay in hospital – the patients should recieve the same kind<br />

of nursing goals, vision and perspective throughout the course of their stay in hospital.<br />

- Safety and quality control – nurses must continously focus on development and an Evidence based practice.<br />

S07:2<br />

THE OPERATING ROOM NURSES EXPERIENCES OF THE MEDICAL EQUIPMENT IN THEIR DAILY WORK<br />

Roman-Emanuel Christine 1 , Hägglund Doris 2<br />

1) Sahlgrenska University Hospital, 2) Örebro University, Sweden<br />

Objective<br />

In the operating team, the operating room nurses are responsible <strong>for</strong> handling and maintenance of the medical<br />

equipment. The knowledge about the operating room nurse’s apprehension of work with medical equipment is<br />

limited. Increased knowledge in this area may increase nurse’s understanding of their role and ultimately, patient<br />

safety. The aim of this study was to describe how the operating room nurse’s experience the importance of the<br />

medical equipment in their daily work and their competence in medical equipment.<br />

Methods<br />

Forty-six operating room nurses working at a University Hospital were included in a prospective qualitative study.<br />

37/46 answered the questionnaire with tree open-ended questions. The answers of the questionnaire were analysed<br />

through a qualitative content analysis method according to Graneheim and Lundmann.<br />

Results<br />

The results demonstrated three main themes. The first theme described an increased understanding of how important<br />

it is to keep up your own competence within the field to ensure patient safety. The second theme described that the<br />

operating room nurse apprehend herself as a key-person in the operating-room teamwork with medical equipment.<br />

The third theme described positive and negative effects of the operating room nurse’s role as responsible <strong>for</strong> the<br />

medical equipment on the working-environment.<br />

Conclusion<br />

The main conclusion is that the competence level of operating room nurses and their experiences of medical<br />

equipment in their daily work influences safety <strong>for</strong> the patient, nursing and teamwork in the operating ward.<br />

STOCKHOLM, SWEDEN 53


S07:3<br />

SURGICAL TEAM MEMBER’S EXPERIENCES, ROUTINES AND VIEWS BEFORE IMPLEMENTATION OF<br />

A TIME-OUT PROTOCOL<br />

Murugesh Shamini 1 , Haugen Arvid 1 , Haaverstad Rune 1 , Slettebø Haldor 1 , Daavoy Grethe 1 , Soefteland Eirik 1<br />

1) Haukeland University Hospital, Norway<br />

Background<br />

Ensuring (1) correct patient (2) correct surgical procedure and (3) correct anatomic site/side <strong>for</strong> surgery is of prime<br />

importance <strong>for</strong> patient safety and may avoid medico-legal cases. Several studies confirm that a “Time-out” be<strong>for</strong>e<br />

the surgical incision can reduce the risk of making mistakes. The objective was to study the medical personnel’s<br />

experiences and views be<strong>for</strong>e implementation of a “Time-out” protocol in our Central Operation Unit (COU).<br />

Methods<br />

This survey was per<strong>for</strong>med as a web-based questionnaire linked to our hospital’s e-mail system sent to all surgeons,<br />

anaesthesiologists, theatre nurses and anaesthesia nurses who were employed at the COU February <strong>2009</strong>. Their<br />

experience with near-misses or mistakes, routines and views regarding the three check points and a “Time-out”<br />

protocol was registered.<br />

Results<br />

Feedback was received from 64% (427/275). Of these 38% had experience with unconfirmed patient identity,<br />

43% positioning on the wrong side, 80% unconfirmed anatomic site/side and 60% prepared <strong>for</strong> another procedure<br />

than planned. 50% of the responders regularly ensure patient identity, 61% regularly ensure operation site/<br />

side and 52% usually ensure the type of procedure. 91% responded positively to a “Time-out” protocol being<br />

implemented in our operating theatres.<br />

Conclusions<br />

This study confirmed that a majority of the surgical team had experiences related to near-misses or mistakes of<br />

concern <strong>for</strong> patient safety. Our present system does not give a sufficient opportunity <strong>for</strong> the surgical team to ensure<br />

the three most important check points be<strong>for</strong>e the incision. The study supports the implementation of a “Time-out”<br />

protocol in our operating theatres.<br />

S07:4<br />

OUT OF HOSPITAL(OOH) MANAGEMENT OF PATIENTS ON LVADS (LEFT VENTRICULAR ASSIST<br />

DEVICES). THE NORWEGIAN EXPERIENCE.<br />

Sorensen Gro 1 , Gude Einar 1 , Holter Marianne 1 , Fiane Arnt 1<br />

1) Rikshospitalet, Norway<br />

The purpose was to describe our program <strong>for</strong> OoH management and what we have learned about challenges, joys<br />

and worries.<br />

Background<br />

15 Ventrassist LVAD <strong>for</strong> heart failure has during the last three years been implanted at the University hospital of<br />

Oslo. 11 patients had LVAD as bridge to transplant and 4 as chronic therapy. The patients were aged 10-65 (mean<br />

38.9) years old. Duration on pump was 4 weeks-22 months. Six patients have been successfully transplanted, one<br />

patient recovered after 13 months, six patients are ongoing and two died early after implant.<br />

The patients had very different family support, social network and length of illness be<strong>for</strong>e implant.<br />

The challenges the patients meet also differ considerably. A training program is planned <strong>for</strong> each patient depending<br />

on their individual situation but will always be focused about how to handle the LVADsystem, how to manage<br />

common daily situations, emergency procedures, exitsite care and monitoring system parametres. In addition to<br />

that, the local hospital will be trained and also have an important role in follow up.<br />

Conclusion<br />

A variety of physical, mental and social issues influenze the ability of the LVAD patient to cope with daily life. Being<br />

confident is the foundation pillar, and it is our responsibility as a team with VAD-coordinators, doctors and nurses<br />

to help them building their own framework. A prospective study will be per<strong>for</strong>med to gain a better understanding of<br />

both patient and caregivers experience and what we as a VAD-team should focus on to optimize the support.<br />

54 www.sats<strong>2009</strong>.org


S07:5<br />

GENDER AND HEALTH-RELATED QUALITY OF LIFE AFTER CARDIAC SURGERY<br />

Gjeilo Kari Hanne 1 , Wahba Alexander 1 , Klepstad Pål 1 , Lydersen Stian 2 , Stenseth Roar 1<br />

1) St. Olavs Hospital, 2) NTNU, Trondheim, Norway<br />

Background<br />

Women undergoing cardiac surgery are older, have more comorbidities and are more functionally impaired than men<br />

be<strong>for</strong>e surgery. It has been argued that gender differences regarding outcome tend to reflect differences that exist<br />

preoperatively rather than differences related to cardiac surgery itself. In addition a slower rate of physical recovery<br />

has been shown in female patients. However, the literature is not consistent regarding gender differences in healthrelated<br />

quality of life (HRQOL) outcomes after cardiac surgery.<br />

Design and methods<br />

A prospective study was designed to assess HRQOL in patients undergoing cardiac surgery with emphasis on<br />

gender differences. Between September 2004 and September 2005, 534 patients (413 males and 121 females)<br />

were consecutively included. HRQOL was measured by the Short-Form 36 (SF-36) be<strong>for</strong>e surgery with follow-up<br />

6 and 12 months after surgery.<br />

Results<br />

521 patients were alive after 12 months, 462 (89 %) and 465 (89.4%) responded after 6 and 12 months respectively.<br />

Female patients had less favorable scores than male patients on most subscales of the SF-36 both be<strong>for</strong>e and<br />

after surgery. Both male and female patients improved substantially after surgery, but female patients reported<br />

significantly less improvement on 2 of 8 subscales of the SF-36; role emotional and bodily pain.<br />

Conclusions<br />

The study demonstrates that there are gender differences concerning HRQOL both be<strong>for</strong>e and after cardiac surgery.<br />

However, a clear overall improvement in HRQOL over the first year after cardiac surgery, more specifically during<br />

the first 6 months <strong>for</strong> both genders was found.<br />

S07:6<br />

QUALITY OF LIFE IN PATIENTS AND HIS RELATIVES UNDERGOING PERCUTANEOUS PULMONARY<br />

VALVE IMPLANT<br />

Andresen Brith 1 , Døhlen Gaute 1 , Mathisen Lars 1 , Andersen Marit 1 , Lindberg Harald 1 , Fosse Erik 1<br />

1) Rikshospitalet, Norway<br />

Background<br />

The total number of patients with congenital heart disease is increasing. Many of these patients need repeatedly<br />

open heart surgery. Percutaneous pulmonary valve implant may reduce the total number of surgical events.<br />

Aim<br />

To examine the patients and their familys experience of postoperative convalescence and return to daily activity after<br />

treatment. This study is a pilot to a comparative clinical study where two different treatment techniques are used.<br />

Methods: Patients and relatives were included in a cohort study and underwent both a semi structured interwiew<br />

and a specially designed questionnaire (T.M.Achenbach, 2001).<br />

Preliminary results<br />

Eight patients median age 17 have been treated with PPVI at University Hospital of Oslo. The patients stayed<br />

median 3 days in hospital. Five of the patients and their family returned to daily activity from one to six days after<br />

the event. Three of the patients emphasized less pain as a positive issue. It was confirmed by five parents that the<br />

short hospital stay had a positive influence both on their family situation and their job relations. Less absence from<br />

work was emphasized as a positive socio-economic factor among parents. Seven of the patients had started one<br />

or two physical activities three months after the intervention. Improved school achievement and better ability in<br />

concentration was stated by 5 of the parents, six mentioned improved socialization with friends.<br />

Conclusion<br />

This novel technique seems to offer lesser impact regarding pain and everyday life to both patient and their closest<br />

relatives. It may have a sosioeconomic advantage.<br />

STOCKHOLM, SWEDEN 55


S07:7<br />

ADDRESSING THE SPOUSES UNIQUE NEEDS AFTER CARDIAC SURGERY WHEN RECOVERY IS<br />

COMPLICATED BY HEART FAILURE<br />

Ågren Susanna 1 , Strömberg Anna 2 , Svedjeholm Rolf 3 , Berg Sören 4 , Hollman Frisman Gunilla 1<br />

1) Anesthesia and Intensive Care, 2) European Society of Cardiology,<br />

3) Cardiothoracic Surgery, 4) Cardiothoracic Anesthesiology Intensive, Sweden<br />

Background<br />

Cardiac surgery places extensive stress on spouses who often are more worried than the patients themselves.<br />

Spouses can experience difficult and demanding situations when the partner becomes critically ill.<br />

Objectives<br />

To identify, describe, and conceptualize the individual needs of spouses of patients with complications of heart failure<br />

after cardiac surgery.<br />

Methods<br />

Grounded theory using a mix of systematic coding, data analysis, and theoretical sampling was per<strong>for</strong>med. Spouses,<br />

10 women and 3 men between 39 and 85 years, were interviewed.<br />

Results<br />

During analysis, the core category of confirmation was identified as describing the individual needs of the<br />

spouses. The core category theoretically binds together three underlying subcategories: security, rest <strong>for</strong> mind<br />

and body, and inner strength. Confirmation facilitated acceptance and improvement of mental and physical<br />

health among spouses.<br />

Conclusions<br />

By identifying spouses’ needs <strong>for</strong> security, rest <strong>for</strong> mind and body, and inner strength, health care professionals can<br />

confirm these needs throughout the caring process, from the critical care period and throughout rehabilitation at<br />

home. Interventions to confirm spouses’ needs are important because they are vital to the patients’ recovery.<br />

S07:8<br />

PATIENT EDUCATION IN A REPRESENTATIVE SAMPLE OF PATIENTS HAVING ELECTIVE CARDIAC<br />

SURGERY IN ICELAND<br />

Olafsdottir Heida Steinunn 1 , Ingadottir Brynja 1 , Sveinsdottir Herdis 1 ,<br />

1) Landspitali University Hospital, Iceland<br />

Aim<br />

The aim of this study was to describe the perceived education and satisfaction with that education among patients<br />

undergoing elective cardiac surgery (CABG +/- AVR or AVR) at the Landspítali University Hospital in Iceland.<br />

Method<br />

This study used a descriptive, prospective correlational panel design. Data were collected with a questionnaire, at the<br />

hospital and at home six weeks later. Questions addressed patient education, symptoms, support and satisfaction<br />

with education, care and support as well as anxiety and depression that were measured with the Hospital Anxiety<br />

and Depression Scale. 111 patients who had surgery from January 15 until July 15, 2007, were invited to participate<br />

and 66 accepted.<br />

Findings<br />

The data analysis is not yet completed. The findings will describe the patients’ anxiety, symptoms, pain, perceived<br />

education and support and the correlation between those variables.<br />

Conclusion<br />

The preliminary findings indicate that the nursing care of cardiac surgery patients could be improved by identifying<br />

patients who are anxious per-operatively and provide them with individualised patient education at the hospital.<br />

Introducing post discharge follow-up is likely to increase patient satisfaction and recovery at home.<br />

56 www.sats<strong>2009</strong>.org


S09<br />

<strong>SATS</strong> CARDIOTHORACIC ORAL ABSTRACT SESSION<br />

S09:1<br />

OUTCOME AFTER PULMONARY METASTASECTOMY: ANALYSIS OF SURGICAL RESECTIONS<br />

DURING A 5 YEAR PERIOD.<br />

Hornbech Kåre 1 , Ravn Jesper B. 1 , Steinbrüchel Daniel A. 1<br />

1) Rigshospitalet, Denmark<br />

Objective<br />

Pulmonary metastasectomy <strong>for</strong> a wide range of different primary malignancies has become a progressively accepted<br />

treatment in patients with metastatic disease confined to the lungs. In the present single center study we analyze<br />

the results of management of pulmonary metastases in 5 years consecutive operations. We aim to define patients<br />

who are most likely to benefit from surgery by investigating long-term survival and prognostic factors associated<br />

with prolonged survival in a recent study population.<br />

Methods<br />

The data on all consecutive patients who underwent pulmonary metastasectomy between 2002 and 2006 were<br />

reviewed retrospectively. In total 178 patients underwent 256 surgical resections <strong>for</strong> suspected pulmonary metastases<br />

from different primary malignancies.<br />

Results<br />

Complete resection was achieved in 247 cases (96.4%). 25 patients (9.7%) had benign lesions and 25 patients<br />

(9.7%) had a primary lung cancer. 30-day morbidity and mortality were 6.6% and 1.9% respectively. Mean follow-up<br />

was 49.5 ± 17.8 months. The 5-year survival after metastasectomy according to primary tumour was: colorectal<br />

carcinoma 53.3%, sarcoma 20.9%, malignant melanoma 26.7%, renal cell carcinoma 38.1% and miscellaneous<br />

primary malignancies 50.0%. Of the prognostic factors analyzed by univariate analysis none were significant in all<br />

the different groups of cancers.<br />

Conclusions<br />

Pulmonary metastasectomy is a safe and effective treatment that leads to possible long-term survival in selected<br />

patients. Low morbidity and mortality rates in contrast with the lack of any other effective oncological treatment<br />

justify the aggressive approach of surgery. Solid prognostic factors need to be established.<br />

S09:2<br />

SURGICAL RESECTION OF PULMONARY METASTASES FROM COLORECTAL CARCINOMA IN ICELAND<br />

Vidarsdottir Halla 1 , Moller Pall 1 , Jonasson Jon Gunnlaugur 1 , Gudbjartsson Tomas 1<br />

1) Landspitali University Hospital, Iceland<br />

Background<br />

Over half of patients operated <strong>for</strong> colorectal cancer are later diagnosed with recurrent disease, most often<br />

metastases in the liver or lungs. Pulmonary metastases can be removed surgically; however, the survival benefit has<br />

been debated. The aim of this study was to study surgical outcome of pulmonary metastasectomy in a well defined<br />

patient cohort.<br />

Materials and methods<br />

All patients that underwent complete pulmonary resection of metastatic colorectal carcinoma from 1984-2008.<br />

Average follow up was 41 months.<br />

Results<br />

Altogether 32 procedures on 27 patients were per<strong>for</strong>med (age 63.5 yrs, range 35-80, 63% males). 19 with colon<br />

(70%) and 8 with rectal cancer (30%).The disease-free-interval was 29 months (range, 0-74) and 5 patients had<br />

undergone prior metastasectomy of the liver. Pre-thoracotomy CEA level was elevated in 9 of the patients. Eighteen<br />

patients had a solitary and 6 had two pulmonary nodules, other patients having multiple nodules. Lobectomy (n=18)<br />

and wedge resection (n=14) were the most common procedures. Three patients were operated <strong>for</strong> bilateral and 3<br />

<strong>for</strong> recurrent pulmonary metastases. All patients survived surgery and median length of hospital stay was 8 days<br />

(range, 5-58). Air leakage (19%) and pneumothorax (26%) were the most common complications. One and 5 year<br />

survival was 92.3 and 30.4%, respectively.<br />

Conclusion<br />

Surgical outcome in this series was good with low morbidity and mortality. The 5 year survival was 30.4 %, a much<br />

improved survival compared to patients with metastatic disease in general (


S09:3<br />

THE NO TOUCH VEIN GRAFT HARVESTING TECHNIQUE FOR CABG PRESERVES A FUNCTIONAL<br />

VASA VASORUM<br />

Dreifaldt Mats 1 , Souza Domingos 1 , Loesch Andrzej 2 , Muddle John 2 , Karlsson Mats 1 ,<br />

Norgren Lars 1 , Dashwood Michael 2<br />

1) Örebro University Hospital, Sweden, 2) Royal Free Hospital, United Kingdom<br />

Objectives<br />

To evaluate the impact of vein graft harvesting technique on structure and function of vasa vasorum.<br />

Methods<br />

Segments of great Saphenous veins harvested either with conventional harvesting technique (CT) or no<br />

touch technique (NT) were obtained from patients undergoing CABG. Quantitative measurements, using<br />

immunohistochemistry and morphometry, were per<strong>for</strong>med using a computerised imaging program. Ultrastructural<br />

analysis of vasa vasorum was per<strong>for</strong>med using electron microscopy. Sections of in vitro perfused vein grafts with<br />

infusion of ink into the perfusion line were analysed using light-microscopy. Video footage of flow in an incised vasa<br />

vasorum in an implanted saphenous vein graft harvested with the NT was captured during a CABG operation.<br />

Results<br />

The total area of vasa vasorum in vein grafts harvested with NT was significantly larger both in the media (p<br />

= 0.007) and in the adventitia (p = 0.014) compared to vein grafts harvested with CT. Ultrastructural findings<br />

indicated that NT preserved an intact vasa vasorum while CT did not. Perfusion of vein grafts in vitro showed filling<br />

of ink in vasa vasorum in grafts harvested with NT. Video footage showed retrograde flow in vasa vasorum in vein<br />

grafts harvested with NT.<br />

Conclusion<br />

These findings show that the NT <strong>for</strong> saphenous vein graft harvesting <strong>for</strong> CABG preserves an intact and functional<br />

vasa vasorum. This could represent one of the mechanisms underlying the improved patency <strong>for</strong> vein grafts harvested<br />

with this technique.<br />

S09:4<br />

IS THERE A PLACE FOR TOTAL ENDOSCOPIC ABLATION OF ATRIAL FIBRILLATION?<br />

Ahlsson Anders 1 , Fengsrud Espen 1 , Linde Peter 1 , Tydén Hans 1 , Englund Anders 4<br />

1) Örebro University Hospital, Sweden<br />

Study objective<br />

To evaluate the feasibility, efficacy and safety of total endoscopic ablation (TEA) of atrial fibrillation (AF) using<br />

microwave or radiofrequency energy.<br />

Method<br />

TEA was per<strong>for</strong>med using left single lung ventilation and CO2 insufflation in the right hemithorax. Through three<br />

right-sided working ports, an ablation catheter was positioned on the left atrial wall and a box lesion encircling all<br />

pulmonary veins was created (video demonstration).<br />

Results<br />

23 patients have undergone TEA since the start in May 2007. The indications were symptomatic AF in patients ><br />

50 years, and patients with a BMI > 35 were excluded. The median age was 67 yrs (52 – 83), and 5 patients were<br />

female. The frequency of paroxysmal/persistent/permanent AF were 9/5/9, respectively, and the median duration<br />

of AF 10 years.<br />

9 patients were ablated using a Flex X microwave catheter (Boston Scientific, USA) and 14 patients using a Cobra<br />

Adhere XL radiofrequency catheter (ESTECH, USA). There was no hospital mortality. One patient had a transient<br />

phrenical paralysis and one patient required a small thoracotomy to complete the ablation. The freedom of AF at<br />

follow-up was 7/10 patients (70%) after 12 months. Among radiofrequency ablated patients, the freedom of AF was<br />

9/9 patients after three months and 5/6 after 6 months.<br />

Conclusion<br />

TEA is a feasible method of AF ablation with preliminary acceptable results. The potential clinical role of TEA has to<br />

be further evaluated in prospective, randomised trials with careful monitoring of the AF burden during follow up.<br />

58 www.sats<strong>2009</strong>.org


S09:5<br />

STERNAL CLOSURE WITH THERMOREACTIVE CLIPS IN 1000 HIGH RISK PATIENTS<br />

- A SINGLE CENTRE COHORT STUDY.<br />

Balasubramanian Sendhil Kumaran 1 , Dunning Joel 1 , Avlonitis Vassilios 1 , Gill Michael 1 ,<br />

Goodwin Andrew 1 , Owens Andrew 1 , Kendall Simon 1<br />

1) The James Cook University Hospital, United Kingdom<br />

Background<br />

Nitillium thermoreactive clips are a novel method of sternalclosure. These clips are highly pliable at low temperature<br />

making them easy to place round the sternum but stiffen at body temperature. They also demonstrate elasticity<br />

on coughing, returning to their original position rather than cutting through. We sought to assess the incidence of<br />

sternal wound complications using these thermo-reactive clips(flexigrips) in 1,000 high-risk patients and identify the<br />

risk factors <strong>for</strong> deep sternal wound infection (DSWI).<br />

Methods<br />

From May-2004 to August-2008, 1,000 high-risk patients, had sternal closure using flexigrips. Perioperative and<br />

demographic variables were analyzed with univariate and multivariate logistic regression analysis to identify risk<br />

factors associated with DSWI.<br />

Results<br />

Median age was 64yrs and median BMI was 32. 85% were male, 30%diabetics and 75% had hypertension. 74% had<br />

CABG, 9% had valve replacements and 12% had combined procedures.There were no sternal complications in 981<br />

patients (98%). The total incidence of DSWI was 1.9% and sternal dehiscence was 1%. Superficial wound infection<br />

was 8.6%. Overall mortality was 1.6%. Multivariate analysis identified, BMI≥35 (Odds ratio 3.21:95%CI 1.16-8.85),<br />

type-II diabetes (Odds ratio 3.9:95%CI 1.27 – 12.3) and need <strong>for</strong> emergency resternotomy (Odds ratio 7.65:95%CI<br />

2.3-25.19) were significant risk factors <strong>for</strong> DSWI.<br />

Conclusions<br />

Thermo-reactive clips can be safely used <strong>for</strong> sternal closure in these high risk patients with an incidence of sternal<br />

dehiscence of 1%. Incidence of sternal dehiscence requiring surgery is low. BMI≥35, diabetes and mediastinal reexploration<br />

were additional predictors of DSWI.<br />

S09:6<br />

CARDIAC SURGERY IN PATIENTS WITH HAEMOPHILIA<br />

Tang Mariann 1 , Wierup Per 1 , Terp Kim 1 , Ingerslev Jørgen 2 , Sørensen Benny 2<br />

1) Department of Cardiothoracic Surgery, Aarhus University Hospital, Skejby,<br />

2) Center <strong>for</strong> Haemophilia and Thrombosis, Denmark<br />

Background<br />

Today the populations of haemophilia patients have a higher life expectancy than previously known, and age-related<br />

disorders are expected to become more prevalent. Cardiac surgery constitutes a major haemostatic challenge.<br />

Hence, only limited systematic in<strong>for</strong>mation exists on efficacious and safe haemostatic substitution regimens during<br />

and after these major surgical episodes. Furthermore, postoperative thromboprophylaxis with antiplatelet drugs is<br />

questionable and seem problematic in patients with haemophilia.<br />

Aim<br />

Evaluation of our current experience and results with cardiac surgery in patients with haemophilia. Provide detailed<br />

in<strong>for</strong>mation on the haemostatic treatment regimens adopted. Forward systematic details on the organization of<br />

haemostatic treatment regimens and postoperative thromboprophylaxis.<br />

Material & Methods<br />

Six patients with haemophilia A undergoing cardiac surgery. In<strong>for</strong>mation on concomitant disorders and EuroSCORE<br />

was registrated. Outcome measures were: (i)re-operation caused by bleeding, (ii) blood transfusion requirements,<br />

(iii) peri- and postoperative blood loss, (iv) peri- and postoperative complications and (v) postoperative development<br />

of inhibitors. Data was compared with historical data from patients without congenital haemophilia (n = 5977) as<br />

extracted from the Danish Heart Database.<br />

Results<br />

None of the six patients were reoperated due to bleeding and none developed inhibitors. Peri- and postoperative<br />

blood loss ranged from 565 to 1055 ml. No incidence of myocardial infarction or thromboembolic complications was<br />

seen. Data did not deviate from results with non-haemophiliacs undergoing major cardiac surgery. All patients were<br />

substituted with a recombinant factor VIII product.<br />

Conclusion<br />

Major cardiac surgery can safely be per<strong>for</strong>med in patients with congenital haemophilia. Outcome measures were<br />

acceptable in comparison with data from non-haemophiliacs.<br />

STOCKHOLM, SWEDEN 59


S09:7<br />

SURGICAL CORRECTION OF PECTUS EXCAVATUM AND CARINATUM - SIX YEARS OF EXPERIENCES<br />

AT KAROLINSKA UNIVERSITY HOSPITAL.<br />

Bergman Per 1<br />

1) Karolinska University Hospital, Sweden<br />

Objective<br />

The minimally invasive repair of pectus excavatum (p.e), the ”Nuss procedure” and the modified operation technique<br />

of pectus carinatum (p.c), the ”modified Ravitch procedure”, are becoming increasingly popular and has todaybecome<br />

well established and worldwide accepted.<br />

Methods<br />

Between 2004-<strong>2009</strong>, 76 patients in the county of Stockholm were operated at Karolinska (KS) and Clinica<br />

Vistahermosa (CV), Spain by the same surgeon. 46 cases with p.e were operated at KS and 10 cases were operated<br />

at CV. 8 cases with p.c were operated at KS and 12 cases at CV. 14 Pectus Bars (p.e) were also extracted at KS<br />

during this time.<br />

Results<br />

76 patients (68 men,8 women) with mean age of 17 years (range 12-34) were included. Mean time to discharge<br />

was 9 days (range 5-13) <strong>for</strong> Nussprocedure and 7 range (range 5-8) <strong>for</strong> modified Ravitch. Complications such as<br />

pain > 4 weeks occured in 6 patients (8%), intrapleural fluid in 1 patients (1%), small apical pneumothorax ocurred<br />

in 14 patients (25%) but had disappeared at the postop control 1 month later. Superficial infections localized in the<br />

incisions in 2 patients (3%). Deeper infection leading to removal of one stabilizator and one bar removal occured in<br />

2 patients (3%). Bars were removed after 3 years from 14 patients during this time.<br />

Conclusion<br />

These techniques have good outcome and few per/postoperative complications. The cosmetic results were very<br />

satisfying and the operations have very high Quality of Life appearence which also is going to be studied further.<br />

60 www.sats<strong>2009</strong>.org


S10<br />

<strong>SATS</strong> BASIC SCIENCE ORAL ABSTRACT SESSION<br />

S10:1<br />

INJECTION OF MESENCHYMAL STEM CELLS MODIFIED WITH VEGF GENE IN ISCHEMIC<br />

MYOCARDIUM IMPROVES CARDIAC FUNCTION IN RATS<br />

Hua Ping 1 , Yang Yanqi 2 , Chen Ju 1 , Peng Jiangzhou 1 , Chen Bosheng 1 , Han Jie 1 , Wang Youyu 1<br />

1) The 2nd hospital Sun Yat-Sen University, China, 2) University Hospital, Linköping, Sweden<br />

Objective<br />

To observe effect of implantation of mesenchymal stem cells (MSCs) transfected by vascular endothelial growth<br />

factor (VEGF) on myocardium regeneration and angiogenesis in ischemic region, and consequent cardiac function in<br />

rats with acute myocardial infarction (AMI).<br />

Methods<br />

MSCs of Sprague Dawley rat were isolated, cultured, and labeled then with bromodeoxyuridine (BrdU). Some<br />

of them were transfected by adenovirus vector encoding VEGF (Ad.VEGF) gene. AMI was created by ligation of<br />

LAD artery in 40 rats. Four weeks after the ligation, left ventricle ejections fraction (LVEF) was measured with<br />

echocardiography. The rats were divided into four groups with 10 rats in each. Group I: implantation of MSCs<br />

transfected by Ad.VEGF; Group II: implantation of MSCs; Group III: injection of Ad.VEGF; and Group IV: untreated.<br />

Four weeks thereafter, myocardium regeneration and angiogenesis were evaluated with immunohistochemistry.<br />

LVEF measurement was repeated.<br />

Results<br />

MSCs labeled with BrdU were found in the ischemic region in group I and II with incorporation into capillaries, and<br />

stained by TnT antibody. The capillary density of 14.4±1.3/high power field (HPF) in group I and 13.6±1.1/HPF<br />

in group III were significantly higher than that of 5.9±1.7/HPF in group II and 0.00/HPF in group IV (P


S10:3<br />

VALIDATION OF CYSTATIN C WITH IOHEXOL CLEARANCE IN CARDIAC SURGERY.<br />

Brondén Björn 1 , Eyjolfsson Atli 1 , Blomquist Sten 1 , Jönsson Henrik 1<br />

1) Heart and Lung Division, USiL, Sweden<br />

Introduction<br />

Postoperative renal dysfunction after cardiac surgery is not uncommon. Plasma creatinine is the most commonly used<br />

biomarker of glomerular filtration rate (GFR). Serum cystatin C is a more sensitive biomarker of GFR than plasma<br />

creatinine, but has not been validated in cardiac surgery. Iohexol clearance is a reference method <strong>for</strong> determination<br />

of GFR. The aim of this study is to validate cystatin C with iohexol clearance in cardiac surgery.<br />

Method<br />

Twenty-one patients scheduled <strong>for</strong> elective coronary artery bypass grafting (CABG) where prospectively enrolled<br />

in the study. Be<strong>for</strong>e surgery and on the second postoperative day an iohexol clearance was per<strong>for</strong>med. Cystatin<br />

C, creatinine, creatinine clearance and C-reactive protein (CRP) were determined be<strong>for</strong>e surgery and on the first,<br />

second, third and fifth postoperative day.<br />

Results<br />

A strong correlation between iohexol clearance and cystatin C was found both pre- and postoperatively (r = -0.80 and<br />

r = -0.89 respectively) and was stronger than the corresponding correlation <strong>for</strong> creatinine and creatinine clearance.<br />

A significant elevation of cystatin C concentrations was found on the second and third postoperative day, which was<br />

not seen in creatinine concentrations. No correlation was found between CRP, iohexol clearance and cystatin C.<br />

Conclusion<br />

This study validates cystatin C as a marker of glomerular filtration in cardiac surgery. The study did not indicate that<br />

the cystatin C levels were affected as a consequence of the inflammatory response. The study contributes to the<br />

assumption that cystatin C is superior to creatinine in detecting early decline in renal function in cardiac surgery.<br />

S10:4<br />

PLATELET REACTIVITY DURING CARDIOPULMONARY BYPASS (CPB) - CHANGES RELATED TO<br />

POSTOPERATIVE BLEEDING<br />

Ehnsiö Gustaf 1 , Norderfeldt Joakim 1 , Berg Sören 1 , Alfredsson Joakim 1<br />

1) Heart Centre,Linköping, Sweden<br />

Introduction<br />

The use of CPB during CABG surgery is associated with platelet dysfunction and consumption, contributing to<br />

perioperative bleeding. Our aim was to evaluate if platelet activity correlated to blood loss.<br />

Methods<br />

Platelet function in 30 patients undergoing CABG was analyzed using whole blood impedance aggregometry<br />

(Multiplate®) with ADP (adenosin diphosphate), TRAP (thrombin receptor activating peptide), AA (arachidonic<br />

acid) and COL (collagen) as activators. Platelet reactivity and platelet count was analyzed on multiple occasions<br />

perioperatively up to 18h postoperatively.<br />

Results<br />

Platelet reactivity to ADP and TRAP was significantly reduced at 30 minutes of CPB (p


S10:5<br />

THE HUMAN HEART RELEASES CARDIOTROPHIN-1AFTER CORONARY ARTERY BYPASS GRAFTING<br />

WITH CARDIOPULMONARY BYPASS<br />

Tian Yikui 1 , Ruan Xinhua 1 , Laurikka Jari 2 , Laine Seppo 2 , Tarkka Matti 2 , Wei Minxin 1<br />

1) China 2) Finland<br />

Objectives<br />

Cardiotrophin-1 is closely linked to many cardiovascular diseases, such as myocardial infarction and heart failure,<br />

and exhibits cardioprotective effect in ischemia-reperfusion injury. The present study was designed to investigate<br />

the course of CT-1 in patients undergoing coronary artery bypass grafting (CABG) with cardiopulmonary bypass<br />

(CPB), and to evaluate the relationship between plasma CT-1 levels and postoperative cardiac function.<br />

Methods<br />

Twenty-four patients undergoing elective CABG were studied. Radial artery blood samples were collected be<strong>for</strong>e<br />

CPB, 5 and 20 min after reperfusion, and 1, 6, 12 and 24 h after CPB. Coronary sinus blood samples were<br />

collected be<strong>for</strong>e CPB, 5 and 20 min after reperfusion. Plasma CT-1 levels were measured using the ELISA method.<br />

Hemodynamic data were collected.<br />

Results<br />

Peripheral CT-1 levels did not change significantly postoperatively. Trans-myocardial CT-1 levels increased significantly<br />

5 and 20 minutes after reperfusion as compared to baseline. A weak positive correlation (r=0.408, p=0.048) was<br />

found between trans-myocardial CT-1 levels at 20 min after reperfusion and CI at 12 hours after CPB.<br />

Conclusions<br />

The heart secretes CT-1 after ischemic injury. Endogenous CT-1 might be cardioprotective to ischemia-reperfusion<br />

injury in patients undergoing CABG, but the precise mechanism of this effect warrants further research.<br />

S10:6<br />

ACUTE KIDNEY INJURY FOLLOWING CORONARY ARTERY BYPASS SURGERY USING THE RIFLE CRITERIA<br />

Helgadottir Solveig 1 , Indridason Olafur 2 , Sigurdsson Gisli 2 , Sigurjonsson Hannes 2 ,<br />

Arnorsson Thorarinn 2 , Gudbjartsson Tomas 2<br />

1) University of Iceland, 2) Landspitali University Hospital, Iceland<br />

Introduction<br />

Different rates of acute kidney injury (AKI) have been reported following open-heart surgery, ranging from 2 to 30%.<br />

This can be explained by variable study populations and a lack of consensus on AKI-criteria. Using international<br />

criteria we studied the incidence of AKI following CABG.<br />

Material and methods<br />

A retrospective study of all patients that underwent CABG in Iceland, in 2002-2006. Concomitant CABG procedures,<br />

e.g. as part of valve procedures, were excluded. AKI was defined according to the RIFLE criteria, using pre- and<br />

post-op creatinine levels.<br />

Results<br />

Of 569 patients, 97 (17%) had reduced estimated glomerular filtration rate (eGFR200 μmol/L. The mean pre- and post-op creatinine level of the<br />

total study population was 92 and 104 μmol/L, respectively (p=0.0001). Ninety patients (15.8%) experienced AKI;<br />

58 fell into RISK, 16 in INJURY and 16 in FAILURE categories. Patients with AKI were 4.1 yrs older (p=0.0001) and<br />

had lower pre-op eGFR (72 vs. 80 mL/min/1.73m2, p=0.009). Female gender (28% vs. 16%, p=0.01), hypertension<br />

(74% vs. 59%, p=0.01) and acute surgery (11% vs. 2%, p


S18<br />

PHYSIOTHERAPISTS ORAL ABSTRACT SESSION<br />

S18:1<br />

PRECAUTIONS AFTER MIDLINE STERNOTOMY. ARE THEY NECESSARY?<br />

Brocki Barbara Cristina 1 , Thorup Charlotte Brun 1 , Skindbjerg Hanne 1 , Svalgaard Marianne 1 , Andreasen Jan Jesper 1<br />

1) Aarhus Univers. Hosp, Denmark<br />

Background<br />

Patients after midline sternotomy are instructed on activity precautions to avoid sternal wound complications. We<br />

question how restrictive those precautions must be, since they can lead to a decrease in quality of life in the<br />

postoperative period.<br />

Aims<br />

To identify mechanical stress factors causing sternal instability and infection in order to draw up evidence based<br />

guidelines <strong>for</strong> activity after sternotomy.<br />

Methods<br />

Literature review (CINAHL, Pub Med, Cochrane Library and PEDRO) and crosschecking references.<br />

Results<br />

Mechanical stress factors acting upon the sternum and the overlying skin are: constant coughing, BMI ≥ 35, skin<br />

stress due to macromastia, excessive bilateral arm movements leading to skin breakdown, and loaded activity with<br />

long lever arm. Our recommendations <strong>for</strong> precautions after midline sternotomy are: avoid stretching both arms<br />

backwards at the same time <strong>for</strong> 10 days; use leg rolling with counterweighting when getting in and out of bed; only<br />

move arms within pain free range; protect sternum when coughing by crossing the arms in a “self hugging” posture;<br />

use supportive sternal vest when coughing constantly or when BMI ≥ 35, use supportive bra when breast cup ≥D;<br />

loaded activity should be done with the elbows close to the body <strong>for</strong> 6 to 8 weeks.<br />

Conclusion<br />

Cough is considered the most important single mechanical stress factor causing instability. We found no evidence to<br />

support weight limitation regarding activity, as long as the upper arms are kept close to the body, and activity within<br />

pain free range.<br />

S18:2<br />

A RANDOMIZED CONTROLLED TRIAL ON DEEP BREATHING EXERCISES WITH POSITIVE<br />

EXPIRATORY PRESSURE AFTER CARDIAC SURGERY<br />

Urell Charlotte 1 , Emtner Margareta 1 , Breidenskog Marie 1 , Westerdahl Elisabeth 1<br />

1) Physiotherapy, Uppsala University Hospital, Sweden<br />

Objectives<br />

Deep breathing exercises with positive expiratory pressure (PEP) has been shown to be beneficial on oxygenation<br />

after cardiac surgery, but there is no consensus about the optimal duration and frequency of the treatment. The<br />

aim of this study was to investigate the oxygenation effect of deep breathing exercises with PEP, with two different<br />

breathing rates, the first two days after cardiac surgery.<br />

Methods<br />

In a prospective, randomized study 131 patients over 18 years, who underwent cardiac surgery were randomized<br />

in two groups: treatment group (TG) (n=63), 10 deep breaths x 3 in a PEP-device every hour awake the first two<br />

postoperative days and control group (CG) (n=68) 10 deep breaths x 1 every hour awake the first two postoperative<br />

days. The main outcome measures were arterial blood gases. Tests were per<strong>for</strong>med the second postoperative day.<br />

Result<br />

Mean age was 68.5 years and 25% were women. TG had significantly higher arterial oxygen tension (PaO2 8.9 ±<br />

1.7 kPa vs 8.1 ± 1.4 kPa p= 0.004) and arterial oxygen saturation (SaO2 92.7 ± 3.7 % vs 91.1 ± 3.8%, p= 0.016)<br />

compared to the CG. Both groups had the same compliance to the breathing exercises.<br />

Conclusion<br />

A higher breathing rate resulted in an improved oxygenation and the groups had the same compliance to the exercises.<br />

There<strong>for</strong>e a higher breathing rate should be recommended the two first postoperative days after cardiac surgery.<br />

64 www.sats<strong>2009</strong>.org


S18:3<br />

PHYSICAL ACTIVITY ON PRESCRIPTION (FAR®)-A LONG TERM FOLLOW-UP OF FAR® PRESCRIBED<br />

AT A UNIVERSITY HOSPITAL<br />

Wennman Susanna 1 , Ståhle Agneta 2 ,<br />

1) Karolinska University Hospital, 2) Karolinska Institutet, Dep. NVS, Sweden<br />

Background<br />

The use of FaR® to patients with high risk <strong>for</strong> lifestyle related diseases and as a treatment <strong>for</strong> different diseases has<br />

increased recently. The effects on FaR® have mostly been studied in primary health care settings. There is a lack<br />

of data regarding long-term effects.<br />

Objective<br />

To evaluate long-term effects of prescribing FaR®.<br />

Method<br />

The patients (n=34) who received FaR® after a physiotherapeutic intervention at Karolinska University Hospital,<br />

Solna, and participated at the follow-up twelve months later answered standardized questions regarding adherence,<br />

self-reported physical activity and health.<br />

Result<br />

The most frequent diagnosis <strong>for</strong> patients receiving FaR were cardiovascular, pulmonary or kidney diseases. A<br />

majority of the patients (65%) were physically active as prescribed or active in other activities. The remaining<br />

patients had a lower self-reported physical activity level and health. An increased physical activity level was<br />

measured among those who adhered to the prescription (p=0.05). There was no significant difference in selfreported<br />

health among those patients who adhered to the prescription and those who did not.<br />

Conclusion<br />

To prescribe FaR® is an effective method to positively influence self-reported physical activity level and the<br />

adherence to the prescription is very good.<br />

Key-words: counseling, life style, physical therapy, primary prevention, public health<br />

STOCKHOLM, SWEDEN 65


P01<br />

POSTER SESSION<br />

P01:01<br />

PLATELET IMPEDANCE AGGREGOMETRY AND POSTOPERATIVE BLOOD LOSS AFTER CORONARY<br />

ARTERY BYPASS SURGERY<br />

Roman-Emanuel Christine 1 , Thimour-bergström Linda 1 , Önsten Linda 1 , Rexius Helena 1 , Jeppsson Anders 1<br />

1) Sahlgrenska University Hospital, Sweden<br />

Objective<br />

Platelet dysfunction may contribute to increased bleeding after cardiac surgery but is difficult to assess. Impedance<br />

whole blood aggregometry is a new point-of-care method to evaluate platelet function. We investigated in an ongoing<br />

study if there is any correlation between impedance aggregometry, and bleeding and transfusions after<br />

coronary artery bypass grafting (CABG).<br />

Methods<br />

Fifty-five consecutive CABG patients (men age 67+-9 years, 13% women) were included in a prospective observational<br />

study. 52/55 patients were treated with aspirin and 26 were also treated with the ADP receptor blocker clopidogrel<br />

within seven days be<strong>for</strong>e surgery. Platelet impedance aggregometry (Multiplate®) with adenosine-diphosphate<br />

(ADP) and thrombin receptor activated peptide 6 (TRAP) as activators, was per<strong>for</strong>med after induction of anesthesia<br />

and at sternum closure. Correlation between platelet aggregometry and postoperative bleeding was calculatedwith<br />

Spearman’s Rank sum test and platelet aggregometry variables were compared between transfused and nontransfused<br />

patients with student’s T-test.<br />

Results<br />

Mean postoperative blood loss was 561+-308 ml/12h and 20/55 patients (36%) were transfused with blood<br />

products. There was no significant correlation, neither between pre- and post-operative ADP-induced platelet<br />

aggregation and postoperative blood loss (r=-0.22, p=0.10 and r=–0.06, p=0.66,respectively) nor between pre-<br />

and post-operative TRAP-induced platelet aggregation and postoperative blood loss (r=0.06, p=0.68 and r=0.11,<br />

p=0.41). Furthermore, there were no significant differences in pre- and post-operative aggregometry variables<br />

between transfused and non-transfused patients.<br />

Conclusions<br />

Platelet function, as measured with impedance aggregometry with ADP and TRAP as activators do not correlate to<br />

postoperative bleeding and transfusion requirements after CABG.<br />

66 www.sats<strong>2009</strong>.org


P01:02<br />

A COMPARISON OF ANTICOAGULANTS IN WHOLE BLOOD PLATELET IMPEDANCE AGGREGOMETRY<br />

IN CABG PATIENTS<br />

Thimour-Bergström Linda 1 , Roman-Emanuel Christine 1 , Jeppsson Anders 1<br />

1) Sahlgrenska University hospital, Sweden<br />

Objective<br />

Impedance aggregometry is a new method to evaluate platelet function. Blood samples are collected in test tubes<br />

with anticoagulants and analyzed in a point-of-care device. We investigated if blood samples from CABG patients<br />

collected in tubes with hirudin and citrate gives comparable results.<br />

Methods<br />

Twenty CABG patients (mean age 66 +10 years) were included in a prospective observational study. 19/20 patients<br />

were treated with aspirin and 10 were also treated with the ADP receptor blocker clopidogrel within seven days<br />

be<strong>for</strong>e surgery. Platelet impedance aggregation (Multiplate®), with adenosine-diphosphate (ADP) and thrombin<br />

receptor activated peptide 6 (TRAP) as activators, was measured after induction of anesthesia and at sternum<br />

closure. Aggregation was expressed as area under the curve. Absolute difference, relative difference and correlation<br />

coefficients (r) were calculated.<br />

Results<br />

In ADP-induced aggregation was the absolute difference between hirudin and citrate tubes -7±11 units (13±12 vs<br />

5±4 units) and the relative difference -27±78%. There was no significant correlation between hirudin and citrate<br />

tubes aggregation (r=0.25, p=0.11). In contrast, there was a strong correlation between hirudin and citrate tubes in<br />

TRAP induced aggregation (r=0.84, p


P01:04<br />

RIGHT VENTRICULAR 3-D ARCHITECTURE IS PRESERVED DURING EXPERIMENTALLY INDUCED<br />

RIGHT VENTRICULAR HYPERTROPHY<br />

Nielsen Eva 1 , Smerup Morten 1 , Agger Peter 1 , Frandsen Jesper 1 , Lunkenheimer Paul P. 2 ,<br />

Anderson Rober H. 3 , Hjortdal Vibeke 1 ,<br />

1) Aarhus University Hospital, Skejby, Denmark, 2) University Münster, Germany,<br />

3) University Collage, London, United Kingdom<br />

Introduction<br />

The three-dimensional architecture of the myocytes in the right ventricular (RV) myocardium is a major determinant<br />

of function, but as yet no investigator-independent methods have been used to characterize either the normal<br />

or hypertrophied state. Our aim was to assess and compare, using diffusion tensor MRI (DTMRI), the normal<br />

architecture with the arrangement induced by chronic hypertrophy.<br />

Materials and methods<br />

20 female piglets were randomized into either pulmonary trunk banding or sham operations. RV hypertrophy was<br />

assessed by in vivo cardiovascular MRI after 8 weeks. Hereafter hearts were excised and fixated, and DTMRI was<br />

per<strong>for</strong>med to determine the helical angles of the myocytes aggregated within the walls, and the presence of any<br />

reproducible tracks <strong>for</strong>med by the aggregated myocytes.<br />

Results<br />

All banded animals developed significant RV hypertrophy, albeit no difference was observed in terms of helical<br />

angles or myocardial pathways between the banded animals and those undergone the sham operation. Helical<br />

angles varied from approximately 70º endocardially to -50º epicardially. Very few tracks were circular, with helical<br />

angles approximating zero. Reproducible patterns of chains of aggregated myocytes were observed in all hearts.<br />

Discussion<br />

The 3D-architecture of the RV is comparable to that found in the LV, although the RV lacks the extensive zone of<br />

circular myocytes found in the mid-portion of the LV walls. These circular tracks were also not observed in the RVs<br />

of banded animals. Without such beneficial architectural remodeling, the porcine RV seems unsuited structurally to<br />

sustain a permanent afterload increase.<br />

P01:05<br />

SURGERY FOR MYXOMA: A 10 YEAR EXPERIENCE<br />

Bondo Jørgensen Louise 1 , Steinbrüchel Daniel A. 1<br />

1) Rigshospitalet, Denmark<br />

Introduction<br />

Myxoma is a benign neoplasm that represents the most common primary tumor of the heart accounting <strong>for</strong> about<br />

50 % of all benign cardiac tumors. Despite its benign pathology this tumor may cause significant complication and<br />

mortality by affecting blood flow and causing arrhythmias and emboli.<br />

Material/Methods<br />

The records of 35 patients which underwent surgery <strong>for</strong> cardiac myxoma at Rigshospitalet, Copenhagen, identified<br />

during the period 1998 to 2008 were reviewed. Patients aged ranged from 23 to 90 years (median age 60); women<br />

predominated by a ratio of 1.2:1.<br />

In 29 patients the tumor was located in the “left side” of the heart (left ventricle/atrium), in 7 patients the myxoma<br />

was found in the right atrium/ventricle.<br />

Results<br />

In 8 patients the myxoma was found accidentally, 9 presented with emboli (cerebral or pulmonary), 18 patients were<br />

investigated du to cardiac symptoms. No significant differences with respect to age, gender, BMI or tumor pathology<br />

could be demonstrated in patients presenting with emboli compared to patients with cardiac symptoms. In 6 patients<br />

CABG , valve surgery or MAZE was per<strong>for</strong>med apart from myxoma resection. 30 day mortality was 2/35 (stroke/<br />

acute MI), 3 patients died during a median 4 year follow op.<br />

Conclusion<br />

Although cardiac myxoma is a benign disease, this tumor <strong>for</strong>m must be classified as potentially fatal due to a<br />

risk of embolisation. An embolic event was the initial clinical manifestation.in 25% of the patients. There<strong>for</strong>e an<br />

echocardiography should be considered in adults and young adults with cerebral or pulmonary embolism.<br />

68 www.sats<strong>2009</strong>.org


P01:06<br />

CARDIAC MYXOMA IN ICELAND - A NATION-WIDE CASE SERIES<br />

Sigurjonsson Hannes 1 , Andersen Karl 1 , Gardarsdottir Marianna 1 , Petursdottir Vigdis 1 , Klemenzson Gudmundur 1 ,<br />

Gunnarsson Gunnar Thor 1 , Gudbjartsson Tomas 1<br />

1) Landspitali University Hospital, Iceland<br />

Introduction<br />

Myxoma is the most common benign primary tumor of the heart, usually presenting with symptoms of systemic<br />

emboli or intracardiac obstruction. In recent years, incidental finding is also common. We studied all myxomas<br />

diagnosed in a well defined population during a 23 year period.<br />

Material and methods<br />

A retrospective population-based study including all patients diagnosed with cardiac myxoma in Iceland from 1986<br />

until March 1, <strong>2009</strong> (> 4300 operations per<strong>for</strong>med). Cases were identified through three different registries and<br />

databases.<br />

Results<br />

Nine cases were identified (3 males, 6 females) with mean age of 60.7 yrs (range 37-85). Age-adjusted incidence<br />

rate was 0.12 (95% CI: 0.05-0.22) per 100.000. Eight of the tumors were located in the left atrium and one in the<br />

right atrium. Average diameter was 4.4 cm (1.5-8.0). Dyspnea (n=5) and ischemic stroke (n=2) were the most<br />

common symptoms. Seven of the cases were diagnosed with transthoracal echocardiography and 2 with chest CT,<br />

one of them incidentally. All 9 patients underwent surgical resection, mean operation time being 238 min. All patients<br />

survived surgery and atrial fibrillation (n=5) was the most common complication. Median length of hospital stay was<br />

21 days and today (March 1, <strong>2009</strong>), 7 of the 9 patients are alive with no signs of recurrent disease.<br />

Conclusions<br />

Cardiac myxomas have similar incidence, presenting symptoms and mode of detection in Iceland as in other series.<br />

To our knowledge this is the first study reporting the incidence of cardiac myxoma in an entire population.<br />

P01:07<br />

TOPICAL NEGATIVE PRESSURE OVER CONVENTIONAL THERAPY OF DEEP STERNAL WOUND<br />

INFECTION IN CARDIAC SURGERY. PROSPECTIVE ANALYSIS.<br />

Simek Martin 1 , Hajek Roman 1 , Fluger Ivo 1 , Molitor Martin 1 , Langova Katerina 1 , Grulichova Jana 1 , Lonsky Vladimir 1<br />

1) University Hospital Olomouc, Czech Republic<br />

Introduction<br />

We sought to compare clinical outcomes, in-hospital mortality and 1-year survival of two different treatment<br />

modalities of deep sternal wound infection, topical negative pressure and the conventional therapy.<br />

Methods<br />

Prospective analysis of 66 consecutive patients treated <strong>for</strong> deep sternal infection at our institution. A total of 28<br />

patients (February 2002 through September 2004) underwent conventional treatment, and 34 patients (November<br />

2004 through December 2007) had the application of topical negative pressure. Four patients (July 2004 through<br />

December 2004) who underwent a combination of both strategies were excluded from the study. Clinical and wound<br />

care outcomes were compared, focusing on therapeutic failure rate, in-hospital stay and the 1-year mortality of both<br />

treatment strategies.<br />

Results<br />

Topical negative pressure was associated with a significantly lower failure rate of the primary therapy (p


P01:08<br />

THE EFFECT OF CO2-INSUFFLATION ON THE TEMPERATURE OF THE STERNOTOMY WOUND<br />

Frey Joana 1 , Svegby Henrik 2 , Svenarud Peter 1 , van der Linden Jan 1<br />

1) Karolinska University Hospital, 2) Royal Technical University, Sweden<br />

Background<br />

The open surgical wound is exposed to heat loss through radiation, evaporation and convection. Also, general<br />

anaesthesia contributes to a decrease in body temperature. Mild core hypothermia has been shown to contribute<br />

to cardiovascular morbidity, transfusion demands, delayed wound healing, postoperative wound infections, and<br />

extended hospitalization. A number of measures to prevent core hypothermia have been assessed as to their<br />

effectiveness but warming the open surgical wound by insufflating CO2 has so far not been investigated.<br />

Methods<br />

In 10 patients undergoing heart surgery, the surface temperature of an open cardiothoracic wound was measured<br />

with an infrared camera. Thermographic images were taken 2 minutes after opening of the pericardium, 2 minutes<br />

after insufflating the wound with dry room-tempered CO2 at a flow rate of 5 L/min via a gas diffuser, and 2 minutes<br />

after again exposing the wound to ambient air. Later off-analysis measured the average surface temperature of the<br />

whole wound.<br />

Results<br />

Exposure to CO2 increased the median temperature of the whole wound by 0.5°C (p=0.01) and the two thirds most<br />

distal to the diffuser by 1,2°C (p2 had been turned off. In the area closest to the diffuser the temperature decreased<br />

with 1.8°C (p2.<br />

Conclusion<br />

Short term insufflation of dry room-tempered CO2 in an open surgical wound cavity increases the surface temperature<br />

of the whole wound significantly. However, the temperature of the area closest to the diffuser decreased, most<br />

propably due to convection.<br />

P01:09<br />

THE PECTORALIS MUSCLE AXIAL FLAP WITH V-Y SKIN PADDLE FOR COVERING OF STERNAL DEFECTS.<br />

Molitor Martin 1 , Simek Martin 1 , Záleaák Bohumil 2 , Lonský Vladimir 1<br />

1) University Hospital Olomouc, Czech Republic<br />

Introduction<br />

Infectious wound complication after cardiovascular surgery is serious problem with high rate of associated morbidity<br />

and mortality and usually lead to wound dehiscence with sternal osteomyelitis and both bone and soft tissue defects.<br />

When infection is managed the reconstruction of the thoracic wall remains the main problem. Tissues used to<br />

cover the defect must be well nourished and suture must be absolutely tension free. We introduce our method of<br />

reconstruction using pectoralis muscle axial flap with V-Y skin paddle.<br />

Method<br />

Right pectoralis muscle is freed in the extent that allows its com<strong>for</strong>table shifting over whole sternal bone and V-Y<br />

skin paddle allows tension free skin suture in the midline.<br />

Results<br />

In the period of 2007-<strong>2009</strong> we have per<strong>for</strong>med four flaps. In two patients haematoma occured in the site of disconected<br />

humeral head of pectoralis muscle, in one patient in the proximal midline suture. In one patient peripheral necrosis<br />

of the distal part of the flap occured that needed resuturing and after that healed completely. All flaps survived and<br />

no dehiscence or other complication in the site of primary defect occured.<br />

Conclusion<br />

Our type of flap is reliable and easy to per<strong>for</strong>me. It has excellent blood supply and allow tension free suture of all<br />

tissues. Nosignificant superficial necrosis can occur in the most peripheral part of the flap. Its main disadvantage is<br />

that it cannot be used in female patients due to breast. Insignificant medial shifting of the areola in male patient is<br />

well tolerated.<br />

70 www.sats<strong>2009</strong>.org


P01:10<br />

CIRCULATORY ARREST AND BRAIN MONITORING<br />

Vainikka Tiina 1 , Wennervirta Johanna 1 , Ångerman-haasmaa Susanne 1 , Mäki Kaisa 1 , Vakkuri Anne 1 ,<br />

Sipponen Jorma 1 , Salminen Ulla-Stina 1<br />

1) Helsinki University Hospital, Finland<br />

Brain monitoring in patients undergoing aortic arch surgery is unreliable. During cardiopulmonary bypass, deep<br />

hypothermia and circulatory arrest, brain damage may occur at any time point.<br />

Prospective patient enrollment started 11/2007. Patients (30) undergoing cardiopulmonary bypass, deep hypothermia<br />

and circulatory arrest are included. CAD patients operated on-pump (15) or off-pump (15) serve as controls. For<br />

brain monitoring, continuous EEG recording and NIRS oximeter are used. Neuropsychological tests are done 6<br />

months postoperatively.<br />

So far 18 patients, F/M = 5/13, 55.6 + 13.8 years, EuroScore 19.3% + 20.0%, were enrolled. Diagnosis was<br />

ascending aortic dissection in 12 and rupture of ascending aortic aneurysm in 1. Elective surgery was per<strong>for</strong>med in<br />

additional 5. Circulatory arrest was 36.9 + 30.1 min. Both-sided (3) or right (5) selective cerebral perfusion was used<br />

in 8 <strong>for</strong> 38.4 + 26.6 min. 2 (6.7%) died intrahospitally, 6 (33.3%) had neurological complications; 3 severe cerebral<br />

infarctions. Neurological complications showed NIRS and/or EEG changes. So far 11 were controlled: 1 died, 2 were<br />

hospitalized <strong>for</strong> stroke, 8 were tested. All 6 not retired were working. 2 patients were intact, 5 showed mild cognitive<br />

changes, 1 was depressed. 10 on-pump controls, F/M = 1/9, 62.8 + 9.3 years, recovered uneventfully, 4 attended<br />

control: 2 were intact and 2 had mild cognitive changes. Of 3 off-pump controls, F/M=0/3, 61.3 + 15.8 years, 2<br />

attended and were intact.<br />

EEG and NIRS monitoring gives in<strong>for</strong>mation of the timing and severity of intra-operative brain damage. In less<br />

severe neurological complications 6-month results are good.<br />

P01:11<br />

NEGATIVE-PRESSURE WOUND THERAPY (NPWT) FOR STERNAL WOUND INFECTION<br />

“THE FIRST CASES IN ICELAND”<br />

Steingrímsson Steinn 1 , Gottfredsson Magnus 2 , Gudmundsdottir Ingibjorg 3 , Sjögren Johan 4 , Gudbjartsson Tomas 2<br />

1) 2) 3) University of Iceland, Landspitali University Hospital, Faculty of Nursing, Uni. of Iceland, Iceland<br />

4) Lund University Hospital, Sweden<br />

NPWT has been shown to be effective <strong>for</strong> treating sternal wound infections (SWI). Rather than leaving the wound<br />

open after debridement or use closed irrigation, a sponge is placed in the wound and negative pressure applied. This<br />

reduces bacterial load, increases blood flow and stimulates <strong>for</strong>mation of granulation tissue in the wound. The aim of<br />

this study was to evaluate the results of NPWT <strong>for</strong> SWI in Iceland.<br />

Consecutive case series, including all patients with SWI following cardiac surgery that required surgical revision,<br />

diagnosed between July 2005 and Dec 2008. During this period all patients with SWI were treated with NPWT.<br />

12 patients (age 69 yrs, 10 males, 9 following CABG) were identified (1,3% infection rate). Coagulase-negative<br />

staphylococci (n=6) and Staphylococcus aureus (n=4) were the most common pathogens. NPWT was initiated<br />

on the 19th day postoperatively (median, range 5-111) and the duration of treatment was 14 days (median, range<br />

5-36). In most cases (9/12) the sternal-wires were removed and the sponges replaced 2-8 times. Primary closure<br />

of the sternum was achieved following NPWT in 10 out of 12 cases. In one case of Pseudomonas aeruginosa<br />

infection, NPWT treatment failed and this patient was treated successfully with vinegar soaked gauzes. No major<br />

complications were directly related to NPWT, however one patient died of sepsis related to SWI. The other 11<br />

patients are alive today (Jan. <strong>2009</strong>) and without signs of infection.<br />

This small series shows promising results <strong>for</strong> NPWT of SWI in Iceland and that major complications are rare.<br />

STOCKHOLM, SWEDEN 71


P01:12<br />

REOPERATION FOR BLEEDING FOLLOWING OPEN HEART SURGERY IN ICELAND<br />

Smarason Njall 1 , Sigurjonsson Hannes 1 , Hreinsson Hreinsson 1 , Arnorsson Þorarinn 1 , Gudbjartsson Tomas 1<br />

1) Landspitali University Hospital, Iceland<br />

Introduction<br />

Postoperative bleeding is a potentially fatal complication following open heart surgery, with studies reporting a<br />

reoperation-rate <strong>for</strong> bleeding in the range of 2-6%. In Iceland surgical outcome after such reoperations has not been<br />

studied be<strong>for</strong>e.<br />

Material and methods<br />

This retrospective study included all adults that underwent open heart surgery in Iceland between 2000-2005, and<br />

were reoperated <strong>for</strong> bleeding.<br />

Results<br />

There were 103 reoperations (mean age 68 yrs, 76% males), out of 1295 open heart procedures per<strong>for</strong>med during<br />

the same period, giving a reoperation-rate of 8%. One third of the patients were taking aspirin and 8% clopidogrel<br />

less than 5 days be<strong>for</strong>e surgery. The bleeding in the primary operation averaged 1523 ml (range 300-4780) and<br />

3942 ml <strong>for</strong> the first 24 hours postoperatively. Every other patient was reoperated on within 2 h and 97% within<br />

24 hours. The patients received 16.5 units of packed cells, 15.6 units of plasma and 2.3 sets of thrombocytes. The<br />

most common postop complication was atrial fibrillation (58.3%), pleural effusion that needed drainage (24.3%),<br />

myocardial infarction (23.3%) and sternal wound infection (11.7%). Median length of stay was 14 days (range 6-85),<br />

including 2 days (range 1-38) in the ICU. Operative mortality was 15.5% and 1-year crude survival 79.6%.<br />

Conclusion<br />

Reoperation-rate of 8% is in the higher range compared to other studies. Bleeding is a serious complication, with<br />

high morbidity and significant mortality. Furthermore, cost is increased due to expensive transfusions and extended<br />

hospital stay. This emphasizes the necessity to find means to reduce post-operative bleeding.<br />

P01:13<br />

SURGICAL TREATMENT OF NEUROENDOCRINE BRONCHIAL TUMORS AT KAROLINSKA UNIVERSITY HOSPITAL<br />

Brodin Daniel 1 , Bergman Per 1 ,<br />

1) Karolinska University Hospital, Sweden<br />

Objective<br />

Due to the excellent prognosis of typical carcinoids (TC), parenchymal saving has been addressed <strong>for</strong> discussion<br />

as an alternative to anatomical resections. But many authors mean that there is not sufficient data to recommend<br />

parenchymal-saving (limited) operations in any carcinoids. The aim of the present study was to determine factors<br />

that could influence the long-time survival of patients treated surgically <strong>for</strong> neuroendocrine bronchial tumors and<br />

thereby help to establish criteria of limited operation.<br />

Methods<br />

The study was based on retrospective analysis of a total of 45 patients who were surgically treated <strong>for</strong> neuroendocrine<br />

bronchial tumours between 1987-2004. Cumulative survival was estimated by the Kaplan Meier method. Differences<br />

in survival were tested using log rank test.<br />

Results<br />

The 45 patients constituted 9 % of all operated and diagnosed lung tumours. Twenty-four were classified with TC,<br />

five with atypical carcinoids (AC), nine with small cell lung cancer (SCLC) and three with large cell lung cancer<br />

(LCNE). Four patients with carcinoids could not be further sub-classified. Overall 5-year survival rate was 73 %, <strong>for</strong><br />

TC 96 %, AC 60 %, SCLC 22 % and LCNE 33%. Smokers and men had a shorter survival compared to non-smokers<br />

and women. Patients with AC had a higher mean age (67.9) than patients with TC (57.6).<br />

Conclusion<br />

There is a favourable outcome <strong>for</strong> the TC and these patients could be considered <strong>for</strong> parenchymal-saving<br />

operations.<br />

72 www.sats<strong>2009</strong>.org


P01:14<br />

BILATERAL LUNG VOLUME REDUCTION SURGERY FOR SEVERE EMPHYSEMA<br />

Gunnarsson Sverrir I. 1 , Johannsson Kristinn B. 1 , Gudjonsdottir Marta 2 , Magnusson Björn 3 ,<br />

Beck Hans J. 2 , Gudbjartsson Tomas 1<br />

1) Landspitali University Hospital, 2) Reykjalundur Rehabilitation Center, 3) Neskaupstadur Hospital, Iceland<br />

Introduction<br />

Lung volume reduction surgery (LVRS) can be used as a palliative treatment <strong>for</strong> severe emphysema in appropriately<br />

selected patients. The aim of this study was to evaluate the results of LVRS in Iceland.<br />

Materials and methods<br />

A prospective study of 16 consecutive LVRS patients (age 59 yrs, 10 males) with severe emphysema operated<br />

between 1986 and 2008. Approximately 20% of each lung was excised through a sternotomy, using a linear<br />

stapler. All patients were extubated at the end of the procedure. Function tests were done pre- and 2-4 months<br />

postoperatively.<br />

Results<br />

Average operation time was 86 min. (range 55-135) and hospital stay 26 days (range 9-85). There were no<br />

postoperative deaths and prolonged airleak was the most common complication (n=7). Four patients needed<br />

reoperation; including 3 with sternal dehiscence and one with sternal wound infection. Preoperatively, FEV1 was 0.97<br />

L (33% of predicted) and TLC 7,8 L (132% of predicted), RV 4.5 L (205% of predicted) and exercise capacity 69 W.<br />

Postoperatively FEV1 had increased significantly by 34% to 1,3 L (p=0.004), but other changes were not significant.<br />

Today (April <strong>2009</strong>), 10 out of 16 patients are alive, with median crude survival of 96 months (range 9-151).<br />

Conclusion<br />

In this small series, FEV1 significantly improved after LVRS. All the patients survived surgery, however, complications<br />

were common and hospital stay extended. LVRS appears to benefit some patients with severe emphysema. However,<br />

due to small patient numbers our results have to be interpreted cautiously.<br />

P01:15<br />

SURGICAL RESECTIONS FOR GIANT PULMONARY BULLAE<br />

Gunnarsson Sverrir I. 1 , Johannsson Kristinn B. 1 , Asgeirsson Hilmir 1 , Gudjonsdottir Marta 2 ,<br />

Magnusson Bjorn 2 , Gudbjartsson Tomas 1<br />

1) Landspitali University Hospital, 2) Reykjalundur Rehabilitation Center, Iceland<br />

Background<br />

Giant bullae are large dilated air spaces, often occupying more than 1/3 of the hemithorax in patients with emphysema.<br />

The aim of this study was to evaluate the surgical outcome of resections <strong>for</strong> giant bullae in Iceland.<br />

Materials and methods<br />

A retrospective review of 12 consecutive patients (age 58 yrs, 11 males) with severe emphysema who underwent<br />

bullectomy (8 bilateral and 4 unilateral) in Iceland during 1992-2008. Except <strong>for</strong> one lobectomy per<strong>for</strong>med through a<br />

thoracotomy all patients were operated with wedge resection through sternotomy. In all cases pre- an postoperative<br />

lung function studies were per<strong>for</strong>med.<br />

Results<br />

Average operation time was 91 min (range 75-150). Preoperatively FEV1 was 1.0 L (33% of predicted) and FVC 2.9<br />

L (68% of predicted). Two months postop an 80% increase in FEV1 was noted (1.8 L, 58% of predicted, p=0.015)<br />

but only 7% increase in FVC (2.9 L, 68% of predicted, p=0.6). All patient survived surgery and the most common<br />

complications were prolonged air leak (>7 days) (n=9) and pneumonia (n=2). One patient was reoperated on <strong>for</strong><br />

sternal dehiscience. Median hospital stay was 36 days (range 10-74). Today (May <strong>2009</strong>) 7 patients are alive, but the<br />

other 5 patients died 9 yrs median after the operation (100% 5-year survival).<br />

Conclusion<br />

Results of bullectomy in this small series is good. There was a significant increase in FEV1, major complications were<br />

rare and long-term survival acceptable. Prolonged air leak is a common postoperative complication that prolongs<br />

hospital stay of these patients.<br />

STOCKHOLM, SWEDEN 73


P01:16<br />

PNEUMONECTOMY FOR NON-SMALL CELL LUNG CANCER IN ICELAND: EARLY COMPLICATIONS<br />

AND LONG TERM SURVIVAL<br />

Thorsteinsson Hunbogi 1 , Jonsson Steinn 2 , Alfredsson Hordur 3 , Isaksson Helgi 4 , Gudbjartsson Tomas 3<br />

1) 2) 3) Fac. of medicine, University of Iceland, Dpt. of pulmonology, Dpt. of cardiothoracic surgery,<br />

4) Dpt. of pathology, Iceland<br />

Objective<br />

Pneumonectomy is required <strong>for</strong> large or central non small cell lung cancer (NSCLC). This study aims to investigate<br />

the indications, complications and surgical outcome of pneumonectomy <strong>for</strong> NSCLC in Iceland.<br />

Material and methods<br />

A retrospective study of all pneumonectomies per<strong>for</strong>med <strong>for</strong> NSCLC in Iceland 1988-2007. Clinical in<strong>for</strong>mation was<br />

retreived from medical records and all cases staged using the TNM staging system. Survival and prognostic factors<br />

were evaluated using Cox multivariate analysis.<br />

Results<br />

77 patients (64% males) with mean age of 62.3 yrs. were operated on, 44% on the right side. Mediastinoscopy<br />

was per<strong>for</strong>med in 31% of cases. Most patients were stage I or II (58%), but 17% and 21% were stage III A and IIIB,<br />

respectively. Mean operating time was 161 min., bleeding 1,1 L and hospital stay 11 days. Atrial fibrillation/flutter<br />

(21%), pneumonia (6%), empyema (5%) and respiratory failure (5%) were the most common complications. Three<br />

(3.9%) patients died within 30 and 8 (10.4%) within 90 days of surgery. Five year survival was 21%. Age (HR 1.035),<br />

airway obstruction (HR 2.9), large cell- or adenocarcinoma histology (HR 2.21) and TNM stage IV vs. I (HR 16.5)<br />

were independent predictors of poor survival. Operation in the later 10 year period predicted improved survival (HR<br />

0.55, p= 0,03).<br />

Conclusions<br />

Pneumonectomies <strong>for</strong> NSCLC in Iceland have a low rate of complications and operative mortality. Long term survival,<br />

however, is lower than expected, possibly related to insufficient preoperative staging, with only 1 out of 3 patients<br />

undergoing mediastinoscopy prior to pneumonectomy.<br />

P01:17<br />

MEDIASTINOSCOPY – INDICATIONS AND EARLY COMPLICATIONS.<br />

Olafsdottir Thora Sif 1 , Gudmundsson Gunnar 2 , Björnsson Jóhannes 3 , Gudbjartsson Tomas 1 ,<br />

1) Department of surgery, 2) Department of pulmonary medicine, 3) Department of Pathology, Landspitali, Iceland<br />

Introduction<br />

Mediastinoscopy is an important tool <strong>for</strong> staging lung cancer and evaluating mediastinal pathology. The objective of<br />

this retrospective study was to investigate the indications and safety of mediastinoscopy in a well defined cohort of<br />

patients.<br />

Material and methods<br />

All patients that underwent mediastinoscopy in Iceland between 1983-2007 were included. Clinical in<strong>for</strong>mation was<br />

obtained from patient charts and pathology reports were reviewed. For comparison the study-period was divided<br />

into 5-year periods.<br />

Results<br />

282 operations were per<strong>for</strong>med but in 34 cases data was missing, leaving 248 patients <strong>for</strong> analysis (mean age 59<br />

yrs, range 11-89, 150 males). A steady increase was seen in the number of operations, or 16 compared to 85 during<br />

the first and last periods, respectively (p500 ml (0,8%). There were two operative deaths, one due to a major intraoperative bleeding from a<br />

mediastinal tumor that infiltrated the aortic arch and one from a post-operative pseudomonas pneumonia.<br />

Conclusions<br />

The number of mediastinoscopies is increasing in Iceland, especially as a part of lung cancer staging. Mediastinoscopy<br />

is a safe procedure with low mortality and morbidity.<br />

74 www.sats<strong>2009</strong>.org


P01:18<br />

THYMIC EPITHELIAL TUMORS: HISTOLOGY, STAGING AND THE RESULTS OF SURGICAL REMOVAL<br />

Mariusdottir Elin 1 , Gudbjartsson Tomas 2 , Sigfusson Nikulas 2<br />

1) University of the Iceland, 2) Landspitali University hospital, Iceland<br />

Objective<br />

Most thymic tumors are of epithelial origin with different clinical behavior and prognosis. Our aim was to study<br />

the histological subtype and tumor stage of thymic epithelial tumors in Iceland and evaluate the results of<br />

surgical treatment.<br />

Materials and methods<br />

16 consecutive patients (mean age 61 yrs, 10 males), diagnosed with thymic tumor in Iceland, from 1984 to <strong>2009</strong>,<br />

were studied retrospectively. The histological subtype was determined according to the new WHO classification<br />

(A-C) and the Masoka-system used <strong>for</strong> staging the tumors.<br />

Results<br />

Seven patients had local symptoms (chest pain, cough), seven were diagnosed incidentally and 2 were diagnosed<br />

during a work-up <strong>for</strong> myasthenia gravis. Benign tumours were 12, and thymic carcinomas four (25%). The histological<br />

subtype was type A (n= 4), type AB (n=2), type B1 (n=1), type B2 (n=5) and type C (n=4), with no B3 tumors.<br />

Majority of the tumors were on stage I (n=4) or II (n=5) but the carcinomas were two on each stage, III and IV.<br />

Twelve of the 16 patients underwent a radical resection of the tumor through a median sternotomy. There were no<br />

major complications and all the patients survived surgery. Overall crude survival <strong>for</strong> the 16 patients at 5 years was<br />

56%, 75% <strong>for</strong> thymomas and 0% <strong>for</strong> thymic carcinoma.<br />

Conclusions<br />

Tumors in the thymus are rare, most of them benign thymomas with excellent prognosis. For thymic carcinomas,<br />

however, the prognosis is poor and these patients usually die within one year from diagnosis.<br />

P01:19<br />

MYOCARDIAL REVASCULARIZATION IN PATIENTS WITH SEVERE LEFT VENTRICULAR<br />

DYSFUNCTION, IS ON PUMP BEATING THE PREFERABLE TECHNIQUE?<br />

Abdel Aal Mohamed 1<br />

1) Riyadh, Saudi Arabia<br />

Objective<br />

This study compares early outcomes after on-pump beating-heart CABG and conventional CABG in patients with<br />

ejection fraction (EF) less than 30%.<br />

Methods<br />

From 2005 to 2008, 167 patients with ejection fraction less than 30% underwent CABG on-pump beating-heart<br />

CABG was done in 75 patients (group 1) and 95 patients were done using conventional technique (group2). Twelve<br />

patients in the conventional CABG group required insertion of intra-aortic balloon pump initiation intra-operatively<br />

or postoperatively, whereas only 2 patients required this in the on-pump beating-heart CABG group.<br />

Results<br />

In-hospital mortality was less in the on-pump beating-heart CABG group (2.25% versus 3.68). Twelve patients in the<br />

conventional CABG group required insertion of intra-aortic balloon pump initiation intra-operatively or postoperatively,<br />

whereas only 2 patients required this in the on-pump beating-heart CABG group.The ventilation time was longer<br />

in conventional group it was 10± 12.3 versus 7.6±11.7. No significant difference was found in morbidity including<br />

stroke, renal failure. The incidence of postoperative atrial fibrillation was significantly less in on pump beating group<br />

as compared to CPB group it was happened in 6 patients versus 21 respectively. The duration of intensive care unit<br />

stay was 2.9 ±1.65 in group 1 while it was 3.7± 1.78 group 2. The hospital stay was also shorter in the on-pump<br />

beating-heart CABG group, it was 6.8± 1.43 versus 8.6 ±2.13 and it was significantly difference.<br />

Conclusions<br />

On-pump beating-heart CABG can be per<strong>for</strong>med safely on high-risk patients.<br />

STOCKHOLM, SWEDEN 75


P01:20<br />

SURGICAL REVASCULARIZATION AFTER ACUTE MYOCARDIAL INFARCTION, IS IT RUNNING<br />

AGAINST THE CLOCK?<br />

Abdel Aal Mohamed 1<br />

1) Riyadh, Saudi Arabia<br />

Objective<br />

The optimal timing <strong>for</strong> surgical revascularization after acute myocardial infarction (MI) remains controversial. Higher<br />

mortality <strong>for</strong> emergency coronary artery bypass grafting (CABG) after acute myocardial infarction (AMI), ranging<br />

from 5% to 30%, has been documented since the early 1970.<br />

Patients and methods<br />

We examined our experience retrospectively in 278 patients who underwent CABG between 2005 and 2007 at<br />

king Fahad cardiac center in king khaled university hospital, Riyadh, Saudi Arabia. We had three groups one who<br />

underwent CABG within 24hours (group 1) , group 2 between 1 to 3 days and last group 3 after 14 days.<br />

Results<br />

The operative mortality associated with increasing time intervals between MI and CABG were 11.68%, 7.05%,<br />

2.5 %, <strong>for</strong> group 1(within 24 hours), group 2 and 3 respectively. In comparison, the incidence of cerebrovascular<br />

(CVA) and atrial fibrillation (AF) were greater in group 1 and the length of ICU stay was longer <strong>for</strong> patients<br />

undergoing CABG early after MI (within 24 hours). Emergency coronary artery bypass grafting (CABG) after<br />

AMI within 24 hours (group 1) has a significantly higher risk.<br />

Conclusion<br />

Nonemergency surgical revascularization can be done safely at any time interval after acute myocardial infarction,<br />

certainly after 72 hours, without increase in operative mortality and acceptable<br />

P01:21<br />

SURVIVAL BENEFIT OF CORONARY ENDARTERECTOMY IN PATIENTS UNDERGOING COMBINED<br />

VALVE AND CORONARY BYPASS GRAFTING<br />

Javangula Kalyana 1 , Papaspyros Sotoris 1 , Nair Unnikrishnan 1<br />

1) Leeds General Infirmary, United Kingdom<br />

Objectives<br />

Coronary Endarterectomy (CE) in patients undergoing coronary artery graft (CABG) surgery has been shown to<br />

be useful in re-vascularization of patients with diffuse disease. We present our experience with CE in patients<br />

undergoing valve surgery combined with coronary bypass.<br />

Methods<br />

Between 1989 and 2008, 237 patients underwent CABG with valve surgery under a single surgeon. Of these, 41<br />

patients had in addition CE. The data was retrospectively obtained from the notes and database. The follow-up<br />

was obtained by telephonic interview. All variables were analyzed by univariate analysis <strong>for</strong> significant factors <strong>for</strong><br />

in hospital mortality. Morbidity and long term survival was also studied. There were 29 males and 12 females with<br />

a mean age of 67.4 ±8.1 and body mass index of 26.3±3.3. Their mean euroscore was 7.6±3.2 and the log euro<br />

score was 12.2 ± 16.1.<br />

Results<br />

In hospital mortality was 9.8% (4 out of 41) with 6 late deaths. Long-term survival at 10 years was estimated to<br />

be 57.2% (95% CL 37.8%-86.6%). Average hospital stay was 12.7±10.43 days. ICU stay was < 48 hours in 32<br />

patients.The symptom relief was noted in majority with only 3 of the survivors having NYHA class II symptoms. One<br />

of the survivors was on nitrates and none required any further percutaneous or cardiac surgical intervention.<br />

Conclusions<br />

Coronary Endarterectomy does not increase mortality in combined procedures. By achieving more complete<br />

revascularization, it may be offering survival benefit in this group of patients. However this needs to be confirmed<br />

on studies with larger number of patients.<br />

76 www.sats<strong>2009</strong>.org


P01:22<br />

URGENT CABG PREDISPOSES PATIENTS TO REOPERATIONS- MAINLY DUE TO EXCESSIVE BLEEDING<br />

Suojaranta-ylinen Raili 1 , Hiippala Seppo 1<br />

1) Helsinki University Hospital, Finland<br />

Treatment of acute coronary syndrome (ACS) demands aggressive anti-thrombotic therapy and occasionally<br />

also mechanical circulatory support. Both may increase the risk of reoperation after urgent CABG surgery. This<br />

retrospective study was focused on the causes of these reoperations.<br />

Methods<br />

The inclusion criteria were urgent or emergent CABG after admission <strong>for</strong> ACS and the use of cardiopulmonary<br />

bypass. Combined operations including valves or other procedures and off-pump surgeries were excluded. 544<br />

patients were found with an estimated 95.7 % coverage of the target population. All patient records were reviewed<br />

to verify the cause of reoperation. The results were compared to a group of elective CABG patients. The odds ratios<br />

with 95% confidence intervals were calculated <strong>for</strong> the relevant events.<br />

Results<br />

The groups were comparable regarding sex, age, perfusion time, number of distal anastomosis and ReDo operations.<br />

The urgent group had significantly higher Euroscore, all patients were exposed to anti-thrombotic therapy and 12.5%<br />

had perioperative intra-aortic balloon pump compared to just 1.1% in the elective group. In the urgent group the<br />

odds were 2,83 (1,40-5,70) <strong>for</strong> a reoperation due to excessive bleeding and 4,11 (1,53-11,04) <strong>for</strong> all other causes<br />

compared to the elective group. The proportion of reoperations <strong>for</strong> surgical bleeding was the same in both groups.<br />

Conclusions<br />

Urgent CABG increased the odds <strong>for</strong> reoperation three to four fold and in two cases out of three the indication was<br />

excessive bleeding. In both groups the cause of bleeding was surgical in more than two reoperations out of three.<br />

P01:23<br />

OBESITY AND THE RATE OF EARLY COMPLICATIONS AFTER CORONARY ARTERIAL REVASCULARISATION<br />

Oddsson Saemundur J. 1 , Sigurjonsson Hannes 1 , Arnorsson Thorarinn 1 , Gudbjartsson Tomas 1<br />

1) Landspitali University Hospital, Iceland<br />

Introduction<br />

Traditionally obesity has been related to increased postoperative morbidity and mortality following open heart<br />

surgery. Recent studies, however, indicate that the association of obesity and complications is not straight-<strong>for</strong>ward,<br />

with some studies even reporting a beneficial association (obesity paradox). The aim of this study was to study this<br />

relationship in a well defined cohort of CABG/OPCAB patients.<br />

Material and methods<br />

A retrospective non-randomised study on all patients that underwent CABG/OPCAB in Iceland from June 2002<br />

to February 2005. There were 279 patients that were divided into two groups, an obese group (defined as BMI ><br />

30 kg/m2) (28%), and a non-obese group (BMI ≤30 kg/m2) (72%). Demographics, risk factors, complications and<br />

operative mortality (OM) of both groups were compared.<br />

Results<br />

Patient demographics were similar in both groups, including the rate of risk factors such as diabetes mellitus,<br />

hypertension and hyperlipidemia (Table 1). Type of surgery (CABG vs. OPCAB) was also comparable, however,<br />

EuroSCORE was significantly lower in the obese group and operation- and cross-clamp time longer. There were no<br />

significant differences in rates of either major or minor complications and the same was true <strong>for</strong> OM. Hospital stay,<br />

bleeding and transfusion requirements were also comparable between groups.<br />

Conclusion<br />

Obese patients seem to do as well as non-obese patients following coronary arterial revascularisation, at least<br />

regarding short-term complications and OM. Because obese patients had significantly lower EuroSCOREs, the<br />

effects of selection bias can´t be ruled out.<br />

STOCKHOLM, SWEDEN 77


P01:24<br />

HOW DOES INTRAOPERATIVE ASSESSMENT OF DISTAL LAD DISEASE TRANSLATE INTO<br />

CLINICAL OUTCOME?<br />

Svedjeholm Rolf 1 , Vanky Farkas 1<br />

1) Linköping University Hospital, Sweden<br />

Objective<br />

It is generally appreciated that the quality of coronary vessels are important <strong>for</strong> successful revascularization.<br />

Intraoperative assessment of coronary vessel quality by inspection, palpation and probing is routinely per<strong>for</strong>med. It<br />

is questionable to what extent an assessment subject to investigator bias translates into clinical outcome. As our<br />

institutional database contained in<strong>for</strong>mation about intraoperative assessment of quality of distal LAD we decided<br />

to investigate this issue.<br />

Method<br />

Data were registered prospectively in a computerized institutional database. 1751 patients had calcification of<br />

distal LAD classified by the surgeon as none, mild, moderate or severe. In 1034 patients it was classified as none<br />

or mild (Group NM) and in 234 patients it was classified as severe (Group S). These groups were compared with<br />

regard to outcome.<br />

Results<br />

Average age did not differ between Group S (65±1 years) and Group NM (66±1 years) but the proportion of<br />

patients with diabetes (28.2% v 15.3%; p


P01:26<br />

RETROTHYMIC ROUTING FOR SKELETONIZED INERNAL THORACIC ARTERIES:<br />

OPTIMAL LENGTHS, BEST COURSE, MAXIMAL PROTECTION<br />

Kargar Faranak 1 , Pooraliakbar Hamid-reza 1 , Yaghoubi Nahid 1 , Malek Hadi 1 , Aazami Mathias 1<br />

1) Shahed Rajaei Heart Hospital, Iran<br />

Introduction<br />

Routing in-situ internal thoracic arteries (ITAs) towards their coronary targets is a salient technical aspect. The latter<br />

should offer a smooth course providing maximal tension-free lengths, avoid technical flaws as graft kinking or errors<br />

in angulations of sequential anastomoses, decouple in-situ ITAs from respiratory mechanics, and offer protection by<br />

the time of re-sternotomy. In line with a<strong>for</strong>ementioned prerequisites, we report on a new technique <strong>for</strong> routing of the<br />

both right and left ITAs.<br />

Patients and methods<br />

Since 2007 to present, 158 patients (mean age 59.53±9.3 years; female: 25.6%; mean preoperative EF: 43 ±8.36 %;<br />

mean logestic euroscore: 5.75 ± 6.5) underwent CABG using one or both skeletonized ITAs. The ITAs were routed<br />

using the current technique in a retrothymic position towards LAD system, RCA or circumflex artery branches.<br />

Results<br />

158 left and 55 right in-situ ITAs were used. The mean number of grafts per patient was 2.9±0.8 (venous: 1.03±<br />

1.1; arterial 1.87±0.96). 90 % of LITA was used to feed LAD system and 74% of RITA was anastomosed to RCA<br />

branches. A composite arterial graft was per<strong>for</strong>med in 22% and 20% of patients needed concomitant coronary<br />

procedures. The overall hospital mortality was 1.8% and 3.6% of patients suffered perioperative MI mostly due to<br />

extensive concomitant endarterectomy. None of the patients suffered phrenic nerve dysfunction.<br />

Discussion<br />

Retrothymic routing <strong>for</strong> ITAs is a safe and reproducible method. Decoupling in-situ ITAs from respiratory mechanics,<br />

respecting the pleura, and avoiding splitting of the pericardium are some of its technical advantages.<br />

P01:27<br />

NUMBER OF CEREBRAL EMBOLI IS RELATED TO ACCESS SITE AT CORONARY ANGIOGRAPHY<br />

Nyman Jesper 1 , Jurga Juliane 1 , Sarkar Nondita 1 , Tornvall Per 1 , Manilla Maria N. 1 ,<br />

Svenarud Peter 1 , van der Linden Jan 1<br />

1) Karolinska Institute, Sweden<br />

Background<br />

Stroke is a severe but unusual complication during coronary angiography (CA). Recent studies have shown that<br />

particulate cerebral emboli are common during CA, but their role in this context is not entirely understood. The choice<br />

of access site <strong>for</strong> CA might be of importance. The aim of this study was to evaluate if the number of particulate<br />

cerebral emboli when a radial is compared with a femoral access site during CA.<br />

Methods<br />

Patients undergoing CA were randomized to a right femoral or a right radial access site. A transcranial Doppler<br />

(Embodop, DWI, Germany) with bilateral probes was used to continuously register number of particulate emboli<br />

passing each middle cerebral artery (MCA) during CA.<br />

Results<br />

Fifty patients were included, of whom 8 patients were converted from radial to femoral access and are not presented.<br />

The total number of particulate emboli was higher with the radial than with the femoral access site (10.9 ± 6.3<br />

versus 6.9 ± 4.7, p


P01:28<br />

CORONARY ARTERY BYPASS GRAFTING IN ST-MYOCARDIAL INFARCTION. AN ASSESSMENT OF<br />

AVAILABLE GUIDELINE DATA<br />

Myrmel Truls 1 , Eggen Hermansen Stig 1<br />

1) UNN, Norway<br />

Objective<br />

Guidelines <strong>for</strong> treatment of ST-elevation myocardial infarction (STEMI) have been published from the American<br />

Heart <strong>Association</strong> in 2004, and from the European Society of Cardiology in 2008. These guidelines state a lack of<br />

data on timing and selection of patients <strong>for</strong> revascularization by CABG in evolving and established ST-elevation<br />

infarctions.<br />

Methods<br />

A systematic search of PubMed, EMBASE, Clinicaltrials.gov, and Cochrane Central Register on controlled studies<br />

assessing the application of CABG as one trial arm in STEMI.<br />

Results<br />

We found no controlled trials including CABG as the main treatment in one of the trial arms in STEMI-studies. In the<br />

Shock-trial, CABG was part of the early reperfusion-strategy, and the mortality in patients treated by CABG was<br />

equal to percutaneous coronary interventions (PCI).<br />

Conclusion<br />

Data from controlled trials using CABG in STEMI are almost non existent. There are, however, general data supporting<br />

early revascularization. Thus, the use of CABG in STEMI must rely on clinical judgement integrated in a primary<br />

PCI-strategy. There is a number of observational data indicating a too restrictive use of CABG in this setting, most<br />

probably affecting patients with multi-vessel disease.<br />

P01:29<br />

RECOVERY FROM CHRONIC MYOCARDITIS AFTER 14 MONTHS OF SUPPORT BY VENTRAASSIST LVAD<br />

Gude Einar 1 , Sorensen Gro 1 , Andreassen Arne K 1 , Geiran Odd R 1 , Fiane Arnt E 1<br />

1) Oslo University Hospital, Rikshospitalet, Norway<br />

16 years old female was admitted to ourhospital with heart failure after gastroenteritis in Greece. Myocardial<br />

biopsi showed myocarditis with massive leucocyte infiltration, intracellular oedema and cellular destruction.<br />

Echocardiography showed EF 10%, biventricular failure, cardiac output 1.7 l/min.<br />

In cardiogenic shock with VT, she was supported with ECMO, IABP and levosimendan.<br />

VentrAssist LVAD was implanted Sept-07, after 20 days on ECMO.<br />

After reconstruction of femoral artery due to embolus post ECMO, and an increase in liver enzymes responding to<br />

gradual increase in VAD speed she was out of hospital after 30 days, and discharged after 45 days.<br />

From January 2008 a gradual improventent in cardiac function was observed and LVAD explant was planned.<br />

Myocardial biopsi showed chronic myocarditis and inflammatory process until she was successfully treated with<br />

steroids 60 mg tapered down to 5 mg/day after 3 weeks. LVAD removal was delayed by a gastrointestinal infection<br />

with paralytic ileus and sepsis, treated with linezolid 10 days. After recovery invasive candida albicans was detected<br />

and treated <strong>for</strong> 3 weeks without recurrence.<br />

After 413 days with Ventrassist LVAD, ECHO showed EF 50%, LVEDD 45 mm, NT-Pro BNP 35 and normal right heart<br />

hemodynamics also when reducing pump speed to 1250 rpm. VO2 20 ml/kg/min, negative Troponin T. CRP


P01:30<br />

TWO PATIENTS WITH VENTRASSIST SUCCESSFULLY TREATED FOR CANDIDAS ALBICANS.<br />

Gude Einar 1 , Bjornholt Jorgen 1 , Andreassen Arne K 1 , Sorensen Gro 1 , Geiran Odd R 1 , Fiane Arnt E 1<br />

1) Oslo University Hospital, Rikshospitalet, Norway<br />

Infections are a major cause of morbidity and mortality in patients with LVAD.<br />

Secondary to antibiotic use, invasive fungal infections are a feared and well known complication.<br />

We present the history of two Ventrassist patients with invasive candida albicans that were successfully eradicated.<br />

Patient 1. 17 year old female with Ventrassist due to acute myocarditis. Because of myocardial recovery explant of<br />

Ventrassist was planned. After an episode of gastroenteritis complicated by paralytic ileus, Enterobacter cloacae was<br />

detected on a central venous line catheter. After 10 days of treatment with meropenem, Candida albigans was found<br />

in 3 consecutive blood cultures. She was successfully treated with caspofunginacetat <strong>for</strong> 3 weeks. No recurrence of<br />

fungal infection was found in serial blood culture or on explanted LVAD. LVAD successfully explanted.<br />

Patient 2. 52 year old female with Ventrassit due to heart failure. After initial improvement she experienced a<br />

cerebral hemorrage, surgically evacuated complicated by long term respirator use. After treatment with meropenem<br />

and linezolid <strong>for</strong> 12 days <strong>for</strong> Staphylococcus aureus and Enterococcus, Candida albicans was detected in blood<br />

culture. After treatment with caspofunginacetat <strong>for</strong> 3 weeks, fungal infection was no longer detectable in serial<br />

blood cultures. Follow up 3 months. Listed <strong>for</strong> heart transplantation.<br />

Conclusion<br />

Invasive Candida albicans has occured in two of our Ventassist patients secondary to antibiotic use. Both patients<br />

were successfully eradicated without evidense of recurrence. This is in contrast to our previous experience of fungal<br />

infections were <strong>for</strong>eign material must be replaced or removed be<strong>for</strong>e eradication of infection is possible.<br />

P01:31<br />

STRESS INDUCED CARDIOMYOPATHY, TAKOTSUBO SYNDROME, COMPLICATING EARLY<br />

RECOVERY AFTER LUNG TRANSPLANTATION<br />

Hämmäinen Pekka 1 , Virolainen Juha 1 , Eriksson Heidi 1 , Lemström Karl 1 , Piilonen Anneli 1 , Harjula Ari 1 , Sipponen Jorma 1<br />

1) Helsinki University Hospital, Finland<br />

Primary graft dysfunction, infection, and acute rejection are major concerns complicating early recovery after lung<br />

transplantation. We present a case report, in which stress induced cardiomyopathy mimicked severe delayed primary<br />

lung graft failure.<br />

A 56-year-old woman with emphysema was referred <strong>for</strong> lung transplantation. Among other examinations, her<br />

cardiac ECHO showed normal right and left ventricle function, with tricuspid gradient of 31 mmHg, and LV EF<br />

61%. Her coronary angiogram was normal. As suitable donor lungs became available, her CRP was 231 and she<br />

had recurrent pneumonia. The procedure itself was uneventful, and she was extubated 7 hours later. Native lungs<br />

contained macroscopically seen foci of aspergillosis. On 17th postoperative day, she unexpectedly presented twice<br />

grand mal type seizures on ward, after which she was intubated. Next morning chest-xray showed new congestive<br />

features, and pleural effusions were drained. Oxygenation further deteriorated and CT showed extensive alveolar<br />

infiltrates. Infection as well as acute rejection were initially considered possible. However, pro-BNP value, not<br />

determined earlier, was high 12300 ng/l. Cardiac echo showed normal right heart, but left ventricular anteroapical<br />

and posterior walls were largely akinetic, and planimetric estimate of ejection fraction was only 25-30% . The<br />

overall findings were compatible with Takotsubo syndrome. LV function was supported pharmacologically, and the<br />

outcome was excellent.<br />

Takotsubo syndrome has not earlier been described to complicate lung transplantation. Newly transplanted lungs<br />

are highly vulnerable to elevated left atrial filling pressure. Correct diagnosis and avoiding additional antirejection<br />

treatment most probably contributed to eradication of aspergillus.<br />

STOCKHOLM, SWEDEN 81


P01:32<br />

RECIPIENT CELLS IN BRONCHIAL ALLOGRAFTS<br />

Vainikka Tiina 1 , Päiväniemi Outi 2 , Musilová Petra 3 , Alho Hanni 1 , Maasilta Paula 1 ,<br />

Aittomäki Kristiina 1 , Salminen Ulla-Stina 1<br />

1) Helsinki University Hospital, 2) Tampere University Hospital, Finland 3) Veterinary Research Institute, Czech Republic<br />

Lung transplantation is accepted therapy <strong>for</strong> end-stage pulmonary diseases. The main limitation on long-term<br />

survival is obliterative bronchiolits (OB). It is considered a manifestation of chronic allograft rejection. Histologically<br />

OB is manifested as epithelial cell injury, inflammation, fibrosis, and obliteration of the small airways. We studied<br />

recipient cells in bronchial allografts.<br />

29 random-bred pigs were used. Adequate, inadequate or no immunosuppression was given. 2 received control<br />

autografts and 9 male recipients received bronchial allografts from female donors. A series of allografts were<br />

transplanted subcutaneously on the ventral side of donors and were harvested serially during the follow-up.<br />

Histology (H&E) and y-chromosomes (FISH-method) using pig-spesific DNA-label were assessed. Additional 5<br />

female recipients received bronchial allografts from male donors. Samples of lung, liver, kidney and spleen were<br />

taken after 3 months to study y-chromosomes in female recipient organs (FISH).<br />

In male recipients with none or inadequate immunosuppression, rapid epithelial destruction occurred in bronchial<br />

allografts preceding obliteration. Adequate immunosuppression resulted in graft patency until 3 months (p


P01:34<br />

LONG-TERM RESULTS OF MITRAL VALVE REPAIR USING A MADE TO MEASURE GORE-TEX<br />

ANNULOPLASTY RING<br />

Javangula Kalyana 1 , Mushtaq Abid 1 , Papaspyros Sotoris 1 , Nair Unnikrishnan 1<br />

1) Leeds General Infirmary, United Kingdom<br />

Objectives<br />

This study evaluates the long-term results of mitral valve repair using a made to measure Gore-tex Annuloplasty<br />

Ring configured to the actual circumference of the valve.<br />

Methods<br />

A retrospective review was conducted of 39 consecutive patients (mean age 61.6 +/- 10.3 years; range: 26-80 years,<br />

mean Euroscore 6.5) who underwent mitral valve annuloplasty between June 1996 to December 2007. The major<br />

causes of mitral regurgitation (MR) were annular dilatation and prolapse of the posterior leaflet. Quadrangular<br />

resection of the prolapsing posterior cusp was undertaken, when necessary. A 2 mm wide made-to-measure ring<br />

created from a 0.6mm thick Gore-tex, configured to the valve circumference was inserted with interrupted ethibond<br />

sutures supporting the posterior annulus.<br />

Results<br />

One patient with Gillian Barrie Syndrome (2.5%) died late; one (2.5%) had pacemaker insertion and one (2.5%)<br />

needed valve replacement 12 months later following infection. Postoperatively at 8 years the actuarial survival was<br />

92.5% and freedom from re-operation 97.1%. Clinical and echocardiography follow-up continued <strong>for</strong> a mean period<br />

of 6.1 +/- 1.62 years (range: 1.96 to 9.55), and was complete on 21 patients. The mean NYHA functional class at<br />

follow-up was significantly lower than the preoperative score (1.32:2.65, p=0.0008, paired t-test). Pre-operatively<br />

3 patients (14%) had mild MR, 5 (24%) moderate MR and 13 (62%) severe MR. Post-operatively, 13 patients (62%)<br />

had no detectable MR and 8 (38%) had mild MR.<br />

Conclusions<br />

Mitral valve repair using a made-to-measure Gore-tex ring configured to the actual circumference of the mitral valve<br />

is safe, cost-effective, durable and reproducible.<br />

P01:35<br />

THE LEFT ATRIAL ROOF APPROACH (LARI) - AN ASSET FOR MINIMALLY INVASIVE MITRAL SURGERY<br />

Javangula Kalyana 1 , Nair Unnikrishnan 1<br />

1) Leeds General Infirmary, United Kingdom<br />

Background<br />

Adequate exposure and access is fundamental in mitral valve surgery. The conventional approach is interatrial<br />

groove using bicaval venous cannulation. The left atrial roof incision has the potential of facilitating an excellent<br />

exposure of mitral valve through a limited incision without major cardiac tissue trauma, which is particularly desirable<br />

<strong>for</strong> minimally invasive mitral surgery.<br />

We conducted this study to determine the safety, efficacy and technical ease of the LARI.<br />

Methods<br />

Retrospectively collected data of 95 consecutive patients who had mitral valve surgery by the same surgeon in the<br />

last 5 years were analysed. The patients were divided into two groups. Group 1 patients had LARI through minimally<br />

invasive sternotomy (MIS) or full sternotomy. Group 2 patients had the conventional paraseptal incision of the left<br />

atrium through a MIS or full sternotomy. The mitral valve was exposed with LARI in 81 patients (85%). Minimally<br />

invasive technique was used in 19% patients.<br />

Results<br />

More patients in the LARI group regained sinus rhythm on discharge. Concomitant procedures included AVR (25)<br />

TVR (2) AV repair (5) CABG (28) and LA and ventricular volume reduction (5). There was 1 death in group 2.<br />

Conclusions<br />

LARI is a safe technique.Compared to conventional interatrial approach, LARI has short cross clamp and bypass<br />

time. It has the added advantage of reduction in the incidence of AF, ICU stay, total hospital stay. It is feasible in<br />

redo surgery and is ideal <strong>for</strong> supervised surgical training.<br />

STOCKHOLM, SWEDEN 83


P01:36<br />

ACUTE DYSFUNCTION OF MECHANICAL AORTIC VALVE PROSTHESIS DUE TO PANNUS FORMATION<br />

Ellensen Vegard Skalstad 1 , Andersen Knut S. 1 , Segadal Leidulf 1 , Haaverstad Rune 1<br />

1) Haukeland University Hospital, Bergen, Norway.<br />

Background<br />

Acute dysfunction of mechanical prosthetic aortic valves is a life threatening complication. The common symptoms<br />

are chest pain and dyspnoea, which may be intermittent. Loss of valve click is often noticed by the patient or relatives.<br />

Patient history is of utmost importance <strong>for</strong> the diagnosis, which is confirmed by echocardiography, cinefluoroscopy or<br />

both. It is important to differentiate between thrombosis and pannus, as the <strong>for</strong>mer can be treated by thrombolysis,<br />

while the latter should be operated acutely.<br />

Patients and results<br />

We have reviewed 12 patients (13 episodes) suffering from acute dysfunction of a mechanical aortic valve caused<br />

by pannus <strong>for</strong>mation. All patients were initially operated with a monoleaflet aortic valve prosthesis (Medtronic-Hall)<br />

between 1984 and 1999. Mean age at the primary operation was 48 years (range 22-66 years). 67% were female,<br />

33% male. Mean time from primary surgery to acute dysfunction was 11.5 years (range 4.3-24.7 years). One patient<br />

had redo-surgery twice. All the reoperated patients (67%) survived. Four patients (33%) died in-hospital be<strong>for</strong>e<br />

initiation of redo-surgery. The cause of death was confirmed by autopsy.<br />

Conclusion<br />

Acute dysfunction of mechanical aortic valves caused by pannus is a life threatening complication with high mortality.<br />

As soon as the diagnosis is confirmed, redo-surgery should be per<strong>for</strong>med. In our material, the prognosis was good<br />

when the patients were reoperated in time, but bad <strong>for</strong> those who did not reach the operating theatre.<br />

P01:37<br />

EARLY HEMODYNAMIC PERFORMANCE OF PORCINE AND PERICARDIAL PROSTHESES IN<br />

AORTIC POSITION<br />

Påhlman Carin 1 , Nylander Eva 2 , Franzén Stefan 3 , Tamás Éva 3<br />

1) Faculty of Health Sciences, Linköping, 2) Dept. of Clin. Physiology Linköping,<br />

3) Dept. of Cardiothor. Surg., Linköping, Sweden<br />

Background<br />

The per<strong>for</strong>mance of the bioprosthesis after aortic valve replacement (AVR) is of major importance <strong>for</strong> the long-term<br />

outcome and quality of life. The aim of this retrospective study was to compare the early postoperative hemodynamic<br />

per<strong>for</strong>mances of pericardial versus porcine bioprostheses used in our institution.<br />

Methods<br />

The study group included 48 patients operated with isolated AVR in 2008. Hancock II (n=24) implants were compared<br />

to Perimount 2900 (n=24) matched <strong>for</strong> gender, age, body surface area and prosthesis size (labelled 21 to 27).<br />

Transthoracic echocardiography was per<strong>for</strong>med 3-12 days postoperatively.<br />

Results<br />

The pericardial group had a significant lower max velocity and mean gradient (2.62 ± 0.44 m/s, 15.8 ± 4.2 mmHg<br />

versus 3.08 ± 0.44 m/s, 21.8 ± 6.5 mmHg, p


P01:38<br />

MITRAL ANNULOPLASTY WITH A NEW MEDTENTIA RING<br />

Werkkala Kalervo 1 , Simpanen Jarmo 1 , Wirup Per 2<br />

1) Helsinki University, Finland 2) Arhus, Denmark<br />

Medtentia Annuloplasty Ring (MAR) is a new implantable annulus support ring designed to provide support <strong>for</strong> the<br />

mitral annulus. The MAR ring consists of two helical rings and is rotated in place starting at the posterior medial<br />

comissur and rotated 360 degrees so that the lower ring of the MAR slides on the ventricular aspect of the mitral<br />

annulus, underneath all chordae.The MAR ring was tested in 12 adult patients undergoing mitral valve annuloplasty.<br />

In all cases a posterior leaflet prolaps was found and a reduction annuloplasty was per<strong>for</strong>med. thereafter the MAR<br />

was implanted and the position was controlled with a dental mirror. Be<strong>for</strong>e permanent fixation of the conventional<br />

ring the MAR was removed.<br />

The mean time to implant the MAR was 1.5 min ( 0.5-5 min ). At this time no attempt to fix the MAR ring was done<br />

and it was removed. The duration of the removal time was 0.6 min (0.1-2 min).<br />

The MAR ring was easy and quick to implant and explant. During the procedure no damage to the mitral valve and<br />

chordae was noted. In all cases the ring cached all chordae. After implantation the MAR ring needs a quick fixation<br />

method to be easy and rapid method <strong>for</strong> mitral annuloplasty in conventional, minimal and robotic surgery.<br />

P01:39<br />

AORTIC VALVE REPLACEMENT IN THE ELDERLY<br />

Vainikka Tiina 1 , Soisalon-Soininen Sari 1 , Kaartinen Maija 1 , Suojaranta-Ylinen Raili 1 ,<br />

Maasilta Paula 1 , Vento Antti 1 , Salminen Ulla-Stina 1<br />

1) Helsinki University Hospital, Finland<br />

Background<br />

Aortic stenosis rate increases with age. Thus, number of patients undergoing aor-tic valve replacement (AVR) is<br />

expected to grow, when the elderly population is increasing.<br />

Methods<br />

Patients (n=145) undergoing AVR with bioprostheses 1992 - 1997 were followed. At the time of operation, 30 were<br />

> 80 years, 94 were < 80 to > 70 years, and 21 < 70 years old. A follow-up control including echocardiographic<br />

examination took place at least 5 years postoperatively. Follow-up continued until July 31, 2006.<br />

Results<br />

In the oldest group, 30-day mortality was 3.3% and 6.4% in the middle group. In the middle group, 5 valve-related<br />

reoperations were per<strong>for</strong>med. At time of follow-up, 84 (58 %) patients were alive and 60 (71%) attended. LVEF<br />

was improved being > 60% in all groups and the aortic valve gradient was lower than preoperatively in all and most<br />

decreased in the oldest group (p


P01:40<br />

SVO2 A MARKER WITH EXCELLENT SENSITIVITY AND SPECIFICITY FOR CARDIAC MORTALITY AFTER<br />

SURGERY FOR AORTIC STENOSIS<br />

Svedjeholm Rolf 1 , Holm Jonas 1 , Vanky Farkas 1 , Håkanson Erik 1<br />

1) Linköping University Hospital, Sweden<br />

Objective<br />

Adequate monitoring of hemodynamic state is essential after cardiac surgery and vital <strong>for</strong> medical decision making<br />

particularly concerning hemodynamic management. Un<strong>for</strong>tunately commonly used methods to assess hemodynamic<br />

state are poorly documented with regard to outcome. Mixed venous oxygen saturation (SvO2) was there<strong>for</strong>e<br />

investigated after cardiac surgery.<br />

Methods<br />

Detailed data regarding mortality was available on all patients undergoing aortic valve replacement <strong>for</strong> isolated<br />

aortic stenosis during 1995 - 2000 in the southeast region of Sweden (n=396). SvO2 was routinely measured on<br />

arrival to intensive care unit (ICU) and registered in a data base. A receiver operating characteristics (ROC) analysis<br />

of SvO2 in relation to mortality related to cardiac failure and all cause mortality within 30 days was per<strong>for</strong>med.<br />

Results<br />

Area under the curve (AUC) was 0.97 (95% CI 0.96-1.00) <strong>for</strong> mortality related to cardiac failure (p=0.001) and 0.76<br />

(95% CI 0.53-0.99) <strong>for</strong> all cause mortality (p=0.011). The best cut off <strong>for</strong> mortality related to cardiac failure was<br />

SvO2 53.7% with a sensitivity of 1.00 and a specificity of 0.94. Negative predictive value was 100%.<br />

The best cut off <strong>for</strong> all cause mortality was SvO2 58.1% with a sensitivity of 0.75 and a specificity of 0.84. Negative<br />

predictive value was 99.4%<br />

Conclusions<br />

SvO2 on arrival to ICU after surgery <strong>for</strong> aortic stenosis demonstrated excellent sensitivity and specificity <strong>for</strong><br />

postoperative mortality related to cardiac failure and fairly good AUC <strong>for</strong> all cause mortality with excellent negative<br />

predictive value.<br />

P01:41<br />

RESTORING SUBVALVAR CONTINUITY BY REIMPLENTING STRUT CHORDA IN THE SETTING OF<br />

RHUMATIC MITRAL VALVE REPLACEMENT1<br />

Kargar Faranak 1 , Samiei Niloofar 1 , Mohebi Ahmad 2 , Noohi Freidoun 1 , Aazami Mathias 1<br />

1) Shahed Rajaei Heart Hospital, Iran<br />

Introduction<br />

Preserving mitral subvalvar continuity is technically challenging in the setting of rheumatic heart valve disease. We<br />

report on a new technique to restore mitral subvalvar continuity by re-implanting the strut chorda that are primary<br />

mediators of LV-central fibrous body interplay.<br />

Patients and methods<br />

During <strong>2009</strong>, 7 patients (mean age: 48.6 ± 12.6 y.o; female: 57%; mean LVEF: 44.29 %; mean PAP: 51 mmHg;<br />

mean logistic Euroscore: 9.5 ± 8 %) with rheumatic heart valve disease (mitral stenosis: 43%; mitral regurgitation:<br />

14%; mitral stenosis and regurgitation: 43%) underwent mitral valve replacement using the current technique that<br />

consists on preserving mitral subvalvar continuity by reimplanting mitral strut chorda to the mitral annulus and sitting<br />

a mechanical bi-leaflet valve prosthesis in an intra-annular position.<br />

Results<br />

All patients survived on operation; displaying an uneventful postoperative course. 5 patients (71.4%) required one<br />

or more concomitant procedures. The mean pump and ischemic times were 269 and 193 minutes respectively. At<br />

the time of discharge the means LVEF and trans-mitral prosthetic gradient were 42.14 % and 4.2 mmHg (ranged<br />

from 3 to 7) respectively. The re-implanted anterior and posterior strut chorda were identified in all patients on<br />

postoperative echocardiography without inferring with prosthetic valves leaflets.<br />

Conclusions<br />

Restoring the mitral subvalvar continuity by re-implanting the strut chorda is safe and reproducible in patients with<br />

rheumatic heart valve disease. The latter may be more physiologic rather than re-approximating marginal chorda to<br />

the annulus in terms of preservation of LV function that needs to be further investigated.<br />

86 www.sats<strong>2009</strong>.org


P01:42<br />

DAVID PROCEDURE: EARLY AND MID-TERM RESULTS FIVE YEAR EXPIERIENCE<br />

Karciauskas Dainius 1 , Benetis Rimantas 1 , Egle Ereminiene 1 , Povilas Jakuska 1 , Sarunas Kinduris 1<br />

1) Kaunas Medical University, Lithuania<br />

Background<br />

Aortic valve sparing surgery offers a unique opportunity to preserve the aortic valve of patients with aortic root<br />

disease.<br />

Methods<br />

Between January 2004 and April <strong>2009</strong>, David procedure was per<strong>for</strong>med in 21 patients of 827 patients whom<br />

underwent aortic root and valve surgery in the Heart Center of Kaunas University of Medicine. Study protocol<br />

included clinical data (age), patients functional status (NYHA), left ventricule mass index, postoperative major<br />

adverse effects: reoperations <strong>for</strong> bleeding, stroke and lethal outcomes. Patients were observed up to 30 days after<br />

surgery <strong>for</strong> early results and annually <strong>for</strong> mid-term results.<br />

Results<br />

Mean age in group was 51.9 ± 3.3 y. Preoperative status (NYHA) of group was 2.8 ± 0.15. Early mortality rates,<br />

observed within the first 30 days, were only after emergency surgery due to Acute dissection (n=1) and there were<br />

no late mortality events. Reoperation rates due to bleeding events were noted only within first 12 hours: n=4. Annual<br />

doppler echocardiography revealed mild to moderate aortic insufeciency in three patients one year after surgery<br />

with left ventricule mass index reduction from 186.8 ± 13.3 g/m2 to 128.4 ± 12 g/m2. Neither thromboembolic<br />

complications nor stroke events were noted.<br />

Conclusions<br />

Aortic valve-sparing operations according to clinical outcomes are safe but there are some issues related with aortic<br />

valve competence which need full follow-up due to small cohort of patients and sufficient interval of time.<br />

P01:43<br />

TRANSCATHETER AORTIC VALVE IMPLANTATION IN HIGH-RISK SURGICAL CANDIDATES WITH LOW<br />

RISK SCORES<br />

Ahn Henrik 1 , Baranowski Jacek 1 , Freter Wolfgang 1 , Nielsen Niels Erik 1 , Nylander Eva 1 , Tamas Eva 1 , Wallby Lars 1<br />

1) Linköping Heart Center, Sweden<br />

There are patients (pts) with expected high risk at operation that does not get high-risk scores from the traditional<br />

measures as STS or logEuroscores. Among our first 15 pts who underwent a transcatheter aortic valve implantation<br />

there were 3 who principally were accepted after an extensive evaluation of the expected risk of an open chest<br />

operation.<br />

Material and methods<br />

The first pt, a 75 year old man, had been operated 4 years be<strong>for</strong>e with a biological stented prosthesis (Perimount<br />

23 mm) and CABG. The operation was very complicated and the prosthesis became increasingly stenotic. The<br />

other 2 pts, a 60 years old woman and a 66 years old man, had been treated with full dose chest radiation due to<br />

previous malignancies. Both had developed heart failure with aortic stenosis as dominant lesion but mitral valve<br />

disease and secondary tricuspid insufficiency contributed to the clinical picture. The man had previously undergone<br />

a pericardectomy and PCI three times.<br />

The woman had a new malignancy diagnosed, curable but needing surgery without delay.<br />

Results<br />

The valve-in-valve procedure by the transapical approach was uneventful with good position and function of the new<br />

valve (Edwards Lifesciences, Sapien 23 mm). The woman got a Sapien 26 mm valve with good functional result.<br />

The third patient deteriorated quickly after the periods with rapid pacing needing resuscitation in combination with<br />

standard drug treatment. He recovered and showed no neurological symptoms in the early postop period.<br />

Conclusion<br />

Challenging intraoperative problems were avoided by this new catheter based technology.<br />

STOCKHOLM, SWEDEN 87


P01:44<br />

SUBCLAVIAN ARTERY APPROACH IN TRANSCATHETER AORTIC VALVE IMPLANTATION<br />

Holm Peter 1 , Jönsson Anders 1<br />

1) Karolinska University Hospital, Sweden<br />

Objectives<br />

Transcatheter aortic valve implantation (TAVI) has evolved as a therapeutic option with reproducibly good results in<br />

patients (pts) considered to be at high risk <strong>for</strong> complications from conventional surgical valve replacement. Several<br />

thousands of pts have been treated with TAVI worldwide. The experience at our centre since February 2008 is<br />

limited to the CoreValve system. The purpose of this study was to report our experience with TAVI using the left<br />

subclavian artery as vascular access.<br />

Methods and Results<br />

A total of 55 pts with a mean age of 82±6 years and a logistic EUROSCORE of 24±11% underwent TAVI using the<br />

CoreValve prosthesis. In 50 pts the prosthesis was delivered using a transfemoral approach. In 5 pts (3 male) the<br />

left subclavian artery was used <strong>for</strong> access. The decision to use the subclavian artery approach was based on severe<br />

aortic angulations in two patients and inability to create femoral access because of small, calcified or tortuous<br />

femoral arteries in three pts. There was no 30-day mortality in any of the pts operated on using the subclavian artery<br />

as vascular access.<br />

Conclusions<br />

The left subclavian artery can be used as an alternative to create access in patients unsuitable <strong>for</strong> TAVI via the<br />

femoral arteries. This access has in our initial experience some advantages when compared to the femoral artery<br />

approach. The short and straight distance from the introducer positioned in the subclavian artery down to the aortic<br />

annulus offers enhanced stabilization during the expansion of the valve.<br />

P01:45<br />

CAN A PHYSICAL MOBILISATION PROGRAM FOLLOWING OPEN HEART SURGERY INFLUENCE ON<br />

POSTOPERATIVE ROUTINES?<br />

Haukeland Unni Kleppe 1 , Oterhals Kjersti 1 , Drevdal Julie 1 , Lygren Heidi 1 , Njåstad Anita 1 ,<br />

Segadal Leidulf 1 , Haaverstad Rune 1<br />

1) Haukeland University Hospital, Norway<br />

Background and objectives<br />

Pulmonary complications are frequent following open heart surgery. Physical mobilisation is of prime importance<br />

to prevent postoperative respiratory complications. The main objective was to study whether a standard nursing<br />

protocol <strong>for</strong> mobilising patients could stimulate active and early mobilisation in general, and additionally reduce<br />

postoperative pulmonary complications.<br />

Methods<br />

According to the new protocol, minimum mobilisation of 57 patients (intervention group) included sitting in a chair<br />

30 min x 3 1. po. day and 60 min x 3 the 2. day. From day 3 patients should walk about and stay out of bed most<br />

of the day. Retrospectively complications were compared with a matched group of 59 patients (control group) with<br />

routine treatment. The mobilisation was registered in a data <strong>for</strong>m. Clinical and demographic data were collected<br />

from patient files.<br />

Results<br />

The groups were similar with regards to age, gender and preop. risk factors (EuroScore). Mean age of all patients<br />

was 68 ± 12 years, range 27-89 years, and 72 % were men. The study revealed that systemizing respiratory<br />

complications is a difficult task and this will be further analyzed. No differences were found between the groups with<br />

respect to how many times patients were mobilised the first three po. days. However, patients in the intervention<br />

group stayed out of bed <strong>for</strong> longer periods both on day 1 (p = 0.018) and day 2 (p < 0.0001).<br />

Conclusions<br />

A postoperative nursing protocol may improve mobilisation of patients following heart surgery. Increased knowledge<br />

and focus on mobilisation may have influenced positively on mobilising routines on the ward.<br />

88 www.sats<strong>2009</strong>.org


P01:46<br />

TELEPHONE SUPPORT FOR CARDIAC SURGERY PATIENTS AT HOME POST DISCHARGE FROM HOSPITAL<br />

Thorsteinsdottir Steinunn Arna 1<br />

1) Landspitali University Hospital, Iceland<br />

Aims<br />

The aim of this quality project was to explore the educational needs, provide general support and evaluate the<br />

usefulness of telephone-support among cardiac surgery patients one to two weeks post discharge from Landspitali<br />

University Hospital (LUH).<br />

Method<br />

A descriptive exploratory method was used. All cardiac surgery patients (n=17) who were discharged from the<br />

heart-surgery unit at LUH over a one month period in spring <strong>2009</strong> received a phone call from a nurse at the unit.<br />

They received the call 6-15 days post-discharge. A purpose-made checklist was used to collect data on educational<br />

need. The list included questions on physiological and psychological issues. In<strong>for</strong>mation was also sought on use<br />

of health care services post-discharge, satisfaction with education received at the hospital and usefulness of the<br />

telephone call.<br />

Findings<br />

This intervention consisted of patient education, encouragement and support, screening <strong>for</strong> potential complications<br />

and facilitating access to various agents in the healthcare system. Patients expressed satisfaction with the phonecall<br />

and evaluated it as necessary even though they were content with the discharge education received. All of them<br />

had some questions or needed confirmation of their condition as being normal. Pain, problems with the operated<br />

leg, fatigue, oedema and psychological problems were the most common signs and symptoms these patients<br />

experienced.<br />

Conclusion<br />

Telephone-support seems to be a useful intervention <strong>for</strong> this patient group and improves their satisfaction and<br />

security at home. Many un<strong>for</strong>eseen questions and problems arise after discharge and addressing them timely may<br />

enhance recovery and prevent complications to become severe.<br />

P01:47<br />

THE MEMORIES AND EXPERIENCES OF PATIENTS AFTER HEART-SURGERY, AN INTERVIEW STUDY<br />

Sundh Marie 1 , Rylander Hagson Pauline 1<br />

1) Sweden<br />

Previous studies have shown that patients become strongly affected after heart-surgery and a stay in an intensivecare<br />

unit. The aim of this study was to describe the patient’s experiences and memories after open-heart-surgery.<br />

Four patients where included in the study and in-depth-interviews where made in the fourth to fifth day after surgery.<br />

A Qualitative content analysis of the interviews where made, which showed that the patients experienced several<br />

mixed feelings related to the surgery, such as pleasure and anxiety. They experienced how their abilities changed<br />

after the surgery with symptoms as confusion and amnesia. The experiences where affected by factors out of the<br />

patient’s control, such as the routines and environment of the ward. To be cared <strong>for</strong> in an intensive-care unit after<br />

heart surgery was described as a big incident in life and the patients felt the need of empathy, compassion and<br />

warmth. As employees of the ward we were capable of providing many of these needs, but we must not <strong>for</strong>get about<br />

the seriousness of the situation these patients are experiencing and we must never consider it to be a matter of<br />

routine. If we do so, it will show in our actions during the care of these patients and it will contribute to a negative<br />

experience of the patients.<br />

STOCKHOLM, SWEDEN 89


P01:48<br />

NURSING STUDY 30 DAYS AFTER DISCHARGE.<br />

Joergensen Inge Selchau 1 , Tracey Anita 2<br />

1) Aarhus University Hospital, Skejby, 2) Aalborg Hospital, Denmark<br />

Introduction<br />

In connection with The Danish On-pump Off-pump Randomization Study (DOORS) the project nurse contacts the<br />

patient by telephone 30 days after the heart operation. In connection with these interviews the project nurse has<br />

noticed that a lot of the patients experienced different types of problems which the nurses previously didn’t realise<br />

the extent of. The problems occur within the first month following the operation.<br />

Hypothesis<br />

Patients who have undergone a heart operation have problems of physical, psychological and social nature.<br />

Aim<br />

The aim of the investigation is to get a greater kvowledge about and gain an increased insight into the physical,<br />

psychological and social state of health of the patients. In the future this knowledge will be used in the guidance and<br />

in<strong>for</strong>mation the heart patient receives during hospitalization in order that they are better prepared <strong>for</strong> discharge and<br />

their future life with a chronic illness.<br />

Method<br />

Telephone interviews with 350 patients based on a semi-structured interview guide. Focus is on the topics of pain<br />

- medicine administration - compliance, physical activity - exercise, breathing, nutrition - appetite - weight, sleep,<br />

health and discharge. Data will be analysed be means of quantitative content analysis.<br />

Results and conclusion<br />

Quantitative content analysis of the results of the investigation is expected to be carried out during the autumn of<br />

<strong>2009</strong>. Following which conclusion will be drawn and in perspective might have an influence on the care and treatment<br />

of the heart patients in the future.<br />

P01:49<br />

INTRAOPERATIVE CONTAMINATION OF SURGICAL INSTRUMENTS<br />

Persson Jenny 1<br />

1) Karolinska Universitetssjukhuset i Solna, Sweden<br />

Background<br />

Every year 2-5% of all surgical patients in the USA suffers from surgical wound infections, resulting in 500.000<br />

infections and 1.6 billion dollar in additional costs. These complications also results in higher mortality as a complication<br />

to surgery. Several factors are known to influence on the risk of surgical wound contaminations. Pathogens can<br />

contaminate surgical wounds by surgical instruments, which are exposed by all the factors <strong>for</strong> contaminations in the<br />

operating theatre. However, there are very few articles that have study the prevalence of microorganisms on surgical<br />

instruments.<br />

Objectives<br />

To study the prevalence of microorganisms on frequently used surgical instruments in aortic valve surgery with<br />

replacement to a biological implant.<br />

Do microorganisms occur on surgical instruments?<br />

What types of microorganisms occurs on surgical instruments?<br />

Does any step in the intraoperative procedure influence more than another step on the risk of contamination?<br />

Method<br />

The study is planned to be per<strong>for</strong>med with a quantitative method on 20 operations. To handle all factors of<br />

contaminations, and to avoid influence of unwanted factors, the study has to be strictly standardized and controlled<br />

by a test protocol. To determine average and nominal time <strong>for</strong> the predefined steps in the intraoperative procedure,<br />

and to validate the optimal standardized sample collection technique <strong>for</strong> swabbing the instruments, two pilot<br />

studies will be per<strong>for</strong>med. The two most frequently used instruments will be swabbed be<strong>for</strong>e or after a predefined<br />

intraoperative step and samples will be cultivated <strong>for</strong> identification and count.<br />

90 www.sats<strong>2009</strong>.org


P01:50<br />

FINE FEATHERS MAKE FINE BIRDS.<br />

Tracey Anita 1 , Rasmussen Tina Seidelin 2 ,<br />

1) Aalborg Hospital, Aarhus University Hosp, 2) Aalborg Hospital, Denmark<br />

Background<br />

The focus of the study is on the patient’s experience of wearing patient clothing. Patient clothing can be compared<br />

with night wear as it is designed <strong>for</strong> being worn in bed. The experience of wearing patient clothing is described as a<br />

feeling of being naked, anonymous or as if ones personality is camouflaged. Clothing is our cultural skin which finds<br />

expression in the way we’re dressed. By wearing patient clothing the patient shows that he belongs to the patient<br />

culture. Wearing patient clothing can result in decrease in spontaneous activity.<br />

- Why do patients wear patient clothing at all?<br />

- Does patient clothing get like a type of uni<strong>for</strong>m that makes the patient anonymous?<br />

- How can it be that the patient doesn’t choose to wear their own clothes?<br />

- We experience that patient’s behaviour in connection with clothing is distinctly different during hospitalization than<br />

it is in private. Would one <strong>for</strong> example buy bread in the local bakers wearing only nightclothes?<br />

Aim<br />

The Aim is to investigate how patients in a Danish Hospital experience wearing patient clothing during hospitalization<br />

in a post-operative ward.<br />

Method<br />

Participant observation and semi-structured interview are the chosen qualitative methods that are used to create<br />

the empirical material. Each observer observes five patients in their own ward during daytime hours. Following this<br />

ten other patients are interviewed and the interviews are transcribed.<br />

Results<br />

The investigation is expected to be carried out during <strong>2009</strong> with subsequent reporting during the summer of 2010.<br />

P01:51<br />

IS MINI-CPB REALLY LESS HARMFULL THAN THE CONVENTIONAL CPB? THE RESULTS OF<br />

IMMUNOLOGICAL STUDY.<br />

Lonsky Vladimir 1 , Krejsek Jan 1 , Kudlova Manuela 1 , Kolackova Martina 1 , Mandak Jiri 1 , Kubicek Jaroslav 1 , Volt Martin 4<br />

1) Palacky University Hospital, Czech Republic<br />

Background<br />

The cardiac surgical intervention with the use of CPB is accompanied by the activation of complex immunity arm.<br />

This feature is associated with both pro-inflammatory and anti-inflammatory changes. The expression of various pro-<br />

and anti-inflammatory markers were compared between “conventional” and “mini” patients to evaluate potential<br />

benefits of mini-CPB.<br />

Methods<br />

54 patients who underwent primary isolated CABG were prospectively studied. 26 patients (MINI) were operated<br />

upon using a closed circuit IDEAL/SYNERGY, Sorin, Italy, second group of 28 patients (CPB) were operated with<br />

the use of conventional extracorporeal circulation with hardshell reservoir. Peripheral venous blood samples were<br />

collected be<strong>for</strong>e and after surgery and at the 1st, 3rd and 7th postoperative day. The expression of sTNF-alfa R<br />

80kDa, sTNF- alfa R 60kDa, IL-6, IL-10, PMN elastase, MCP-1 as plasmatic markers and CD64 (monocytes and<br />

granulocytes) CD163 (monocytes and granulocytes), CD95 (monocytes and granulocytes), TLR2 (monocytes and<br />

granulocytes), CD254 (monocytes and granulocytes) as cellular markers was studied with the use of flow cytometry<br />

or ELISA assay.<br />

Results<br />

Summarizing our results we can say that almost all studied pro- and anti-inflammatory markers were found to be<br />

significantly less activated in MINI group comparing to conventional CPB at the end of surgery (IL-6 p


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SAS_S14_A5:AD 11/05/09 13:29 Side 1<br />

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