Hayvan Sağlığı Araştırmaları 2009 Yılı Program - Tagem

Fighting and protection from disease depends on the protection of vaccine strains to
field strains, detection of changes in the field and determination of a different vaccine
strain. These methods must be easy and fast. One of these method is Mab production
against FMDV and detection antigenic relation between vaccine strains and field strains.
In this study, nine Mabs are produced and characterized against FMDV type A
strains.These Mabs are defined as non-nötralization. These Mabs recognized an epitope
which is conserved between types A, trypsin resistant, discontinuous and conformational.
After fusions, we evaluated arithmetic mean of colony produce 31.2 %, standart
deviation +- 9, coefficient variation 28 %, standart error +- 2.8, 95 % confidence
interval 24.8-37.5. We acquired 30 % efficiency at the end of this study.
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