Review of Current Evidence and Comparison of Guidelines for ...
Review of Current Evidence and Comparison of Guidelines for ...
Review of Current Evidence and Comparison of Guidelines for ...
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EUR/03/5045931<br />
page 22<br />
Table 3<br />
Late latent/cardiovascular/gummatous<br />
Alternatives Penicillin allergy/parenteral<br />
treatment refused<br />
European Treatment BBP PBP Benzyl Penicillin Doxycycline Tetracycline<br />
United<br />
Kingdom<br />
Dose 2.4 MU 0.6 MU 1 MU 200 mg 500 mg<br />
Regime ow od od od qds<br />
Route IM IM IM po po<br />
Duration 3 weeks 17–21 days 21 days 21–28 days 28 days<br />
Treatment PBP BBP Doxycycline Amoxycillin/<br />
probenecid<br />
Dose 750 mg 2.4g 200 mg 2 g/500 mg<br />
Regime od ow bd tds/qds<br />
Route IM IM po po<br />
Duration 17 days 3 weeks 28 days 28 days<br />
United States Treatment BBP Doxycycline Tetracycline<br />
Russian<br />
Federation<br />
Dose 2.4 MU 100 mg 500 mg<br />
Regime ow bd qds<br />
Route IM po po<br />
Duration 3 weeks 28 days 28 days<br />
Treatment Benzyl Penicillin NBP PBP Ceftriaxone<br />
Dose 1 MU 0.6 MU 1.2 MU 1–2 g<br />
Regime qds bd od od<br />
Route IM IM IM IM<br />
Duration 28 days , 14<br />
days <strong>of</strong>f, 14<br />
days<br />
28 days , 14<br />
days <strong>of</strong>f, 14<br />
days<br />
20 days, 14days<br />
<strong>of</strong>f, 10 days, (28<br />
days in late<br />
visceral)<br />
14 days
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