2010 American Heart Association

heart to arrhythmia. 492–501 Mutations causing cardiac ion channelopathies
are found in 2% to 10% of victims 492–498 and in 14%
to 20% of young adults with sudden death in whom the cause of
death is not evident in a routine autopsy. 499–501 Clinical and
laboratory (eg, ECG, molecular-genetic screening) investigations
of first- and second-degree relatives of patients with sudden
unexplained death reported inherited, arrhythmogenic disease in
22% to 53% of families. 502–505
Therefore when sudden unexplained cardiac arrest occurs in
children and young adults, obtain a complete past medical and
family history (including a history of syncopal episodes, sei-
Guidelines Part 14: PALS Writing Group Disclosures
Writing
Group
Member Employment Research Grant
Monica E.
Kleinman
Leon
Chameides
Stephen M.
Schexnayder
Ricardo A.
Samson
Mary Fran
Hazinski
Dianne L.
Atkins
Marc D.
Berg
Allan R. de
Caen
Children’s Hospital Anesthesia
Foundation–Senior
Associate in Critical Care
Medicine
Emeritus Director Pediatric
Cardiology, Clinical Professor,
University of Connecticut
University of Arkansas for
Medical Sciences—Professor/
Division Chief; †AHA
Compensated Consultant as
Associate Senior Science Editor
The University of Arizona: clinical
care, teaching and research
related to the field of Pediatric
Cardiology in academic
setting-Professor
Vanderbilt University School of
Nursing—Professor; AHA ECC
Product Development—Senior
Science Editor- †Significant
compensation as a paid AHA
consultant to help develop and
edit the 2010 AHA Guidelines for
CPR and ECC.
University of Iowa—Professor
*Compensated worksheet editor
for the 2010 AHA Guidelines.
Money is divided 2/3 to my
institution and 1/3 to me.
University of Arizona - Staff
Intensivist; Asso. Prof. Clinical
Pediatrics, Attending Intensivist,
Pediatric Critical Care Medicine
Self employed, pediatric
intensivist
Disclosures
zures, unexplained accidents or drownings, or sudden unexpected
death at �50 years old) and review previous ECGs.
All infants, children, and young adults with sudden unexpected
death should, where resources allow, have an unrestricted,
complete autopsy, preferably performed by a pathologist
with training and experience in cardiovascular pathology.
Consider appropriate preservation and genetic analysis of tissue
to determine the presence of a channelopathy. Refer families of
patients that do not have a cause of death found on autopsy to a
healthcare provider or center with expertise in arrhythmias
(Class I, LOE C).
Other
Research
Support Speakers’ Bureau/ Honoraria
Ownership
Interest
Consultant/ Advisory
Board Other
None None None None None None
None None None None None None
*Pharmacokinetics of Proton
Pumps inhibitors in Critically
Ill patients
Kleinman et al Part 14: Pediatric Advanced Life Support S895
None None None None *Expert witness in
several cases
involving pediatric
critical care &
emergency
medicine
None None None None None None
None None None None None None
None None None None None *Defense expert
witness for episode
of ventricular
fibrillation in a 2
year old child.
Attorney are
Buckley and
Thereoux of
Princeton, New
Jersey
None None Travel expenses defrayed with an
honorarium of $4000 for speaking
at 13th Asian Australasian
Congress of Anesthesiologists,
Fukuoka, Japan 6/2010
None None None
None None None None None *Medical expert for
Canadian Medical
ProtectiveAssoc
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