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Advances in Food Mycology

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OCHRATOXIN A PRODUCING FUNGI FROM<br />

SPANISH VINEYARDS<br />

Marta Bau, M. Rosa Bragulat, M. Lourdes Abarca,<br />

Santiago M<strong>in</strong>guez and F. Javier Cabañes *<br />

1. INTRODUCTION<br />

Ochratox<strong>in</strong> A (OA) is a nephrotoxic mycotox<strong>in</strong> naturally occurr<strong>in</strong>g<br />

<strong>in</strong> a wide range of food commodities. It has been classified by IARC<br />

as a possible human renal carc<strong>in</strong>ogen (group 2B) (Castegnaro and<br />

Wild, 1995) and among other toxic effects, is teratogenic, immunotoxic,<br />

genotoxic, mutagenic and carc<strong>in</strong>ogenic (Creppy, 1999). W<strong>in</strong>e is<br />

considered the second major source of OA <strong>in</strong> Europe, with cereals<br />

be<strong>in</strong>g the primary source. S<strong>in</strong>ce the first report on the occurrence of<br />

OA <strong>in</strong> w<strong>in</strong>e (Zimmerli and Dick, 1996) its presence <strong>in</strong> w<strong>in</strong>e and grape<br />

juice have been reported <strong>in</strong> a broad variety of w<strong>in</strong>es from different<br />

orig<strong>in</strong>s. Maximum OA levels have been established for cereals and<br />

dried v<strong>in</strong>e fruits <strong>in</strong> the European Union, and it is possible that other<br />

commodities such as w<strong>in</strong>e and grape juices will be regulated before the<br />

end of 2003 (Anonymous, 2002).<br />

Until recently, Aspergillus ochraceus and Penicillium verrucosum<br />

were considered the ma<strong>in</strong> OA-produc<strong>in</strong>g species. P. verrucosum is usually<br />

found <strong>in</strong> cool temperate regions and has been reported almost<br />

exclusively <strong>in</strong> cereal and cereal products while A. ochraceus is found<br />

*Marta Bau, M. Rosa Bragulat, M. Lourdes Abarca and F. Javier Cabañes:<br />

Departament de Sanitat i d’Anatomia Animals, Universitat Autònoma de Barcelona,<br />

08193 Bellaterra, Barcelona, Spa<strong>in</strong>. Santiago M<strong>in</strong>guez: Institut Català de la V<strong>in</strong>ya i el<br />

Vi (INCAVI), Generalitat de Catalunya, Vilafranca del Penedés, Barcelona, Spa<strong>in</strong>.<br />

Correspondence to: Javier.Cabanes@uab.es<br />

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