LabAutomation 2006 - SLAS
LabAutomation 2006 - SLAS
LabAutomation 2006 - SLAS
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<strong>LabAutomation</strong><strong>2006</strong><br />
12:00 pm Monday, January 23, <strong>2006</strong> Track 2: Micro- and Nanotechnologies Room: Pasadena<br />
Wyndham Palm Springs Hotel<br />
Yama Abassi<br />
Co-Author(s)<br />
ACEA Biosciences<br />
Xiaobo Wang<br />
San Diego, California<br />
Xiao Xu<br />
yabassi@aceabio.com<br />
ACEA Biosciences<br />
Electronic Cell Sensor Array Technology for Information Intensive High Content<br />
Cell-Based Assays<br />
ACEA Biosciences has recently introduced the RT-CES system which allows for label-free real-time monitoring of cellular processes such<br />
as cell proliferation, adhesion and viability, using electronic cell sensor array technology. Real-time monitoring of cellular processes by the<br />
RT-CES offers distinct and important advantages over traditional end-point assays. First, comprehensive representation of entire length of<br />
the assay is possible allowing the user to make informed decisions regarding the timing of manipulations or treatments. Second, the actual<br />
kinetic trace of the cells within an assay prior or subsequent to certain manipulations gives important information regarding the biological<br />
status of the cell such as cell growth, arrest, morphological changes and apoptosis. The utility of the RT-CES system in cell proliferation<br />
and cytotoxicity assays for drug discovery as well as receptor-ligand analysis in the context of GPCR and receptor tyrosine kinase assays<br />
will be discussed.<br />
3:00 pm Monday, January 23, <strong>2006</strong> Track 2: Micro- and Nanotechnologies Room: Pasadena<br />
Wyndham Palm Springs Hotel<br />
M. Allen Northrup<br />
MicroFluidic Systems Inc<br />
Pleasanton, California<br />
northrup@mfsi.biz<br />
Integration of Automated Pathogen Detection Systems<br />
Microfluidic Systems Inc. is developing integrated, autonomous bioassay devices and systems for pathogen identification and also for<br />
human DNA isolation. Results that will be presented include the development of microfluidics-based biological sample handling and<br />
processing, cell lysis, nucleic acid purification, flow-through parallel nucleic acid amplification and detection, and rapid immunoassays.<br />
Applications include differential extraction of male and female DNA from a swab sample, and processing and detection of air and waterborn<br />
bacteria, viruses, and toxins, and blood-born viruses.<br />
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