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LabAutomation 2006 - SLAS

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<strong>LabAutomation</strong><strong>2006</strong><br />

Monday, January 23, <strong>2006</strong> Location – Pueblo A, Wyndham Palm Springs Hotel<br />

Deerac Fluidics (Booth 317)<br />

Unit 8, Enterprise Centre, Pearse Street<br />

Dublin 2, Ireland<br />

353(1)6791464; 353(1)6791544 fax<br />

www.deerac.com<br />

An Integrated Solution for Assay Optimization and Kinase Profiling in uHTS Format<br />

Promega and Deerac Fluidics presents an integrated solution for kinase profiling in 1536-well format using Promega’s luminescent Kinase-Glo ®<br />

Plus assay with the Deerac Fluidics Equator HTS dispenser. The attendee learns about the features of the Kinase-Glo ® Plus assay and the<br />

Equator HTS for drug discovery applications. In addition, the attendee learns about a process used for determining optimal kinase assay<br />

parameters with the Equator HTS. Lastly, data is presented showing how these optimal kinase assay conditions can be used with 24-point<br />

titrations of compounds to determine selectivity and potency against a panel of kinases.<br />

Monday, January 23, <strong>2006</strong> Location – Andreas, Wyndham Palm Springs Hotel<br />

Labcyte, Inc. (Booth 477)<br />

1190 Borregas Avenue<br />

Sunnyvale, California 94089<br />

+1.408.747.2000; +1.408.747.2010 fax<br />

www.labcyte.com<br />

Acoustic Droplet Ejection<br />

The Echo 550 liquid handler has been updated with customer-driven improvements. This ”touchless” nanoliter transfer system provides<br />

better results in high-throughput screening by reducing false negatives while dramatically reducing costs. Hear the latest on this technology<br />

from users in the pharmaceutical industry.<br />

Eliminate Edge Effects in Multi-Well Plates<br />

The new MicroClimeTM Environmental lid cuts edge effects by reducing evaporation and hydration. This lid carries a reservoir of fluid<br />

designed to produce a vapor barrier that prevents gas exchange with the outside environment while maintaining a saturated environment<br />

for the wells. See dramatic proof of reduced evaporation and hydration and an example of DMSO dehydration.<br />

Monday, January 23, <strong>2006</strong> Location– Smoketree E – Palm Springs Convention Center<br />

Nanostream, Inc. (Booth 251)<br />

580 Sierra Madre Villa Avenue<br />

Pasadena, California 91107<br />

+1.626.351.8200: +1.626.351.8201 fax<br />

www.nanostream.com<br />

Simultaneous 24-Channel Analyses Using Micro Parallel LC for Drug Release Profiling<br />

Oral osmotically-controlled tablets are designed to have patterned drug delivery profiles. Different drug release profiles (e.g., zero-order<br />

or ascending) can be generated with specific configurations in the extended-release dosage form. Therefore, pharmaceutical analysis of<br />

the drug released from the designed dose has become a critical step in formulation and product development. Scientists must rely on<br />

research tools like micro parallel liquid chromatography (PLC) to accelerate formulation studies while minimizing costs, bench space,<br />

solvent consumption and waste.<br />

In this workshop, Dr. Jerry Yeh, Director of Analytical Sciences at Alza Corporation, discusses how his group applied Nanostream’s PLC<br />

system to simultaneously analyze samples from a United States Pharmacopeia (USP) Type VII apparatus in 24 channels. Dr. Yeh reviews<br />

how data obtained using the PLC system produced a seven-fold concomitant reduction in solvent consumption compared to conventional<br />

HPLC instrumentation.<br />

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