LabAutomation 2006 - SLAS
LabAutomation 2006 - SLAS
LabAutomation 2006 - SLAS
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TP65<br />
Henrik Svennberg<br />
Astrazeneca R&D Molndal<br />
Molndal, Sweden<br />
henrik.svennberg@astrazeneca.com<br />
<strong>LabAutomation</strong><strong>2006</strong><br />
Co-Author(s)<br />
Anna-Karin Norlén<br />
Michael Wirth Färdigh<br />
LLEX and SPEX, Two Work Tools for Control of Tecan Robots During Development of<br />
Liquid-Liquid and Solid Phase Extraction Methods<br />
Sample preparation with Liquid-Liquid Extraction and Solid Phase Extraction is most conveniently performed with the aid of liquid handling<br />
robots, in our case Tecan robots. To avoid extra automation efforts, the sample preparation method should preferably be developed with<br />
the automation equipment intended for the final method. We wanted to make the liquid handling robot available for method development<br />
work by analytical chemists without skills in script writing. Therefore the LLEX and SPEX work tools were designed. They utilise Microsoft<br />
Excel as a user interface for visualised and intuitive robot command input. Some Excel formulas and Visual Basic macros are then used to<br />
create worklists. These worklists are executed by a Gemini script to control the robot. This speech/poster will describe how the work tools<br />
are designed and the use of them will be exemplified with a sample preparation method development for Nexium.<br />
The Microsoft Excel ® user interface made it very convenient for the analytical chemist to set up the method development experiments on<br />
the Tecan robot. New methods for sample preparation were established within a few Tecan runs.<br />
TP66<br />
Bruce Tyley<br />
PerkElmer Life Sciences<br />
Downer’s Grove, Illinois<br />
bruce.tyley@perkinelmer.com<br />
Co-Author<br />
Lois Tack<br />
Positive Sample ID and Tracking with the JANUS Robotic Liquid Handling System<br />
Many key applications, such as forensic DNA processing, compound storage and high through-put screening, require strict tracking of<br />
samples to create sample records or (as required by crime labs) accurate evidence records. During an automated procedure, a sample<br />
can be transferred among several physical locations and container types where various operations in the procedure take place. These<br />
locations, whether test tubes, microtiter plates or other labware, usually are identified by one- and two-dimensional bar codes. Faithful<br />
tracking of samples as they progress through a process can be successfully automated only if the instrument system software captures<br />
and stores all sample activities related to the run.<br />
The JANUS Automated Workstations from PerkinElmer Life and Analytical Sciences support the integration of various bar code reading<br />
devices for tubes and plates. This poster presentation will illustrate how sample data, which are tracked in the JANUS system database,<br />
can be checked and verified according to user requirements. Some examples of these activities include verifying bar coded samples<br />
against laboratory worklist files from a LIMS database, checking that labware has been placed at expected positions on the instrument<br />
deck, and checking for missing and extra samples. Data from a protocol can be extracted from the database and formatted into secure<br />
sample tracking reports. Sample tracking is compatible with all variations of JANUS platforms including both the 4-tip and 8-tip Varispan<br />
arms and the Modular Dispense Technology (MDT) using 96-tip and 384-tip heads.<br />
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