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<strong>UCSI</strong> <strong>University</strong><br />

Faculty of Applied Sciences<br />

School of Applied Sciences<br />

Full Name<br />

Patrick Nwabueze Okechukwu.<br />

Current Position<br />

Lecturer<br />

Academic Qualifications<br />

B Sc. Hons Plant Science and Biotechnology (Biological Sciences)<br />

M Sc. Pharmacology<br />

PhD. Pharmacology (In progress)<br />

Professional Bodies<br />

� The Malaysia Natural Product Society<br />

� The Malaysia Society of Pharmacology and Physiology<br />

� American Society for Pharmacology and Experimental<br />

Therapeutics<br />

� Federation of American Societies for Experimental Biology.<br />

� British Pharmacology Society<br />

Research (any on-going / completed research project)<br />

� IN-Vitro Pharmacology Profile of Alkaloid from Leaves of<br />

Alseodaphne perakensis.<br />

� Purification and Pharmacological (antiulcer, antihypertension,<br />

antidiabetic) Effects of Stem Extract of Coscinium fenestratum<br />

� Purification and Pharmacological (antidiabetic) Effect of Root<br />

Extract of Thottea gradiflora rotteb.<br />

� Purification and Pharmacological (antiulcer, antipyretic,<br />

antinociceptive, and anti-inflammatory) Effects of Extract From<br />

The Leaves of Labisia pumila.<br />

� Quantification and Absorption Studies of Bioactive Compounds<br />

From Stem Extract of Coscinium fenestratum<br />

� Quantification and Absorption Studies of Bioactive Compounds<br />

From The Leaves of Labisia pumila.<br />

� Quantification and Absorption Studies of Bioactive Compounds<br />

From Root Extract of Thottea gradiflora rotteb.<br />

� The Effects of Vitamin-E Supplementation on Bone Proteomics In<br />

Ovariectomised Rats.<br />

� Investigation of anti-inflammatory, anti-pyretic, analgesic,<br />

Antiasthmatic investigation of Yemeni Sidr Honey ( Project<br />

sponsored by Yemani Government).<br />

<strong>UCSI</strong> <strong>University</strong><br />

Kuala Lumpur Campus<br />

No. 1 Jalan Menara Gading, <strong>UCSI</strong> Heights, 56000 Cheras, Kuala Lumpur, W. P. Kuala Lumpur.<br />

Tel: 03-91018880 Fax: 03-91023606 Website: www.ucsi.edu.my


� Investigation of anti-diabetic, anti-ulcer and antioxidant<br />

investigation of Camel urine and milk (Project sponsored by<br />

� Somaliland Government).<br />

Publications<br />

Poster Publication:<br />

1. Adolph William Ndyeabura, Gabriel A. Akowuah and Patrick N.<br />

Okechukwu, Antidiabetic and anti oxidant effect of compounds<br />

isolated from partially purified fraction e ofcoscinium fenestratum<br />

dcm stem extract on stz-induced diabetic rats. 25 rd MSPP Scientific<br />

meeting, May, Malaysia Poster (PP005) 25-26th May 2011.<br />

2. Aman Ahmad Alzubier, Gabriel Akyirem Akowuah and Patrick N<br />

Okechukwu. The evaluation of anti-inflammatory, antipyretic and<br />

analgesic effect of yemeni sidr honey. 25 rd MSPP Scientific<br />

meeting, May, Malaysia Poster (PP009) 25-26th May 2011<br />

3. Loshnie Samuagam, Blessing Emmanuel, Mariani Raja Gopalan ,<br />

Gabriel Akyirem Akowuah, Patrick N Okechukwu, the study of<br />

antinociceptive, analgesic and antioxidant effect of crude and<br />

partially purified labisia pumila leaf extract. 25 rd MSPP Scientific<br />

meeting, May, Malaysia Poster (PP055) 25-26th May 2011.<br />

4. Rufus Pamela Godspower 1 , Gaberiel A. Akowuah 2 and Patrick N.<br />

Okechukwu 2 (2011) The study of anti – ulcer effect of partially<br />

purified DCM extract from the stem of Coscinium fenestratum. 22 nd<br />

Intervasity Biochemistry Seminar Poster (P32) 19 th March 2011.<br />

5. Patrick Nwabueze okechukwu, audrey jiajia Lee,and Gabriel<br />

Akyirem Akowuah In-vitro antihistaminergic, anticholinergic,<br />

antioxidant and mast cell stabilizing effects of partially purified<br />

Labisia pumila leaf extract FASEB J March 17, 2011 25:1020.7<br />

6. Catherine Moyinoluwa Ikujuni, Patrick Nwabueze Okechukwu,<br />

Mariani Rajagopal, Kumutamalar Panrengan, and Gabriel Akyirem<br />

Akowuah Studies on the Anti-inflammatory, Antinociceptive and<br />

Antipyretics activities of extract from Leaves of Labisia pumila<br />

FASEB J April 6, 2010 24:773.5<br />

<strong>UCSI</strong> <strong>University</strong><br />

Kuala Lumpur Campus<br />

No. 1 Jalan Menara Gading, <strong>UCSI</strong> Heights, 56000 Cheras, Kuala Lumpur, W. P. Kuala Lumpur.<br />

Tel: 03-91018880 Fax: 03-91023606 Website: www.ucsi.edu.my


7. Patrick Nwabueze Okechukwu, Connie Boon Ai Ching, Kevin Lai<br />

Kiat Young,Wong Hui Chyn, and Gabriel Akyirem Akowuah The<br />

Study of the Anti-ulcer and Radical Scavenging Effects of Extracts<br />

from the Stem of Coscinium Fenestratum FASEB J April 6,<br />

2010 24:773.1<br />

8. Patrick Nwabueze Okechukwu, Connie Boon Ai Ching, Kevin Lai<br />

Kiat Young,Wong Hui Chyn, and Gabriel Akyirem Akowuah The<br />

Study of the Anti-ulcer and Radical Scavenging Effects of Extracts<br />

from the Stem of Coscinium Fenestratum FASEB J April 6,<br />

2010 24:773.1<br />

9. Boon, AC, Kuar, M, Singh, S, Lai, KYK, Wong, HC, Akuwoah, GA<br />

and Okechukwu, PN (2009) ‘Evaluation of anti-ulcer and radical<br />

scavenging effects of extract from the stem of Coscinium<br />

fenestratum’, 23 rd MSPP Scientific meeting, May, Malaysia Poster<br />

(PP19) 13 th May 2009.<br />

10. Louis, JR, Gan, KC and Okechukwu, PN (2009) ‘Anti-inflammatory<br />

and anti-nociceptive effects of alkaloids from Alseodaphne<br />

perakensis leaf extract’, 20 th Intervarsity Biochemistry Seminar<br />

UPM, March, Malaysia Poster (PP22) 21 st March 2009<br />

11. Murthy, S, Nathans, S and Okechukwu, PN (2008) ‘A study on the<br />

plasma glucose lowering effect of root extract from Thottea<br />

gradiflora Rottb on streptozotocin induced-diabetic rats’, 22 nd<br />

Malaysian Society of Pharmacology & Physiology Science meeting<br />

<strong>University</strong> of Malaya, Malaysia Poster (PP68) 6 th April 2008<br />

12. Murthy, S and Okechukwu, PN ‘Isolation and Evaluation of<br />

antidiabetic effect of DCM extract from the root of Thottea gradiflora<br />

Rottb on streptozotocin induced-diabetic rats’, 19 th Intervarsity<br />

Biochemistry Seminar UTAR, 22 nd March 2008 Poster (PP12)<br />

13. Nathans, S, Tan, HS and Okechukwu, PN (2007) ‘Antidiabetic<br />

Effect of Thottea Grandiflora Rottb Extracts in Streptozocin Induced<br />

Diabetic’, paper presented at the 18 th Intervarsity Biochemistry<br />

Seminar <strong>University</strong> of Malaya, 17 th March , 2007<br />

14. Okechukwu, PN, Rosli, R, Pook, PK, Lajis, N, Soh, KS and Raj, VL<br />

(2006) ‘Biological study (morphine-like and histaminergic) of<br />

partially purified extracts from the leaves of Alseodaphne perakensis<br />

<strong>UCSI</strong> <strong>University</strong><br />

Kuala Lumpur Campus<br />

No. 1 Jalan Menara Gading, <strong>UCSI</strong> Heights, 56000 Cheras, Kuala Lumpur, W. P. Kuala Lumpur.<br />

Tel: 03-91018880 Fax: 03-91023606 Website: www.ucsi.edu.my


(AP)’, poster presented at the 15 th World Congress of<br />

Pharmacology, Poster P30006, Beijing, China 3 rd July 2006<br />

15. Okechukwu, PN, Rosli, R, Pook, PK, Lajis, N, Soh, KS and Raj, VL<br />

(2006) ‘An invitro study of the pharmacological effects of extracts<br />

from the leaves of Alseodaphne perakensis (AP)’, poster presented at<br />

the Experimental Biology 06 (Poster C176), San Francisco, USA 6 th<br />

April 2006<br />

16. Okechukwu, PN, Rosli, R, Pook, PK, Lajis, N, Soh, KS and Raj, VL<br />

(2003) ‘An invitro study of the antihistaminergic and anticholinergic<br />

effects of compounds from the leaves of Alseodaphne perakensis’,<br />

poster presented at the Research and Development Exhibition<br />

Research Management Centre (Poster BAB 77), UPM, Malaysia 22 nd<br />

Nov 2003<br />

Oral Publication:<br />

1. Patrick Nwabueze Okechukwu, Norazlina Mohamed, Ima Nirwana<br />

Soelaiman, Gabriele Anisah Froemming. The Evaluation of Bone<br />

Proteome In Palm vitamin –E Supplemented Ovariectomised Rats, 1 st<br />

Annual Institute of Medical Molecular Biotechnology (IMMB) 25-<br />

26 Novermber 2011, Carlton Holiday & Suites, Shah Alam Malaysia.<br />

2. Patrick Nwabueze Okechukwu, Aman Ahmad Alzubier, Investigation<br />

of anti-inflammatory , antipyretic and analgesic effect of Yemeni Sidr<br />

Honey International <strong>University</strong> Conference (WASET) 2011 August<br />

24-26 Paris, France.<br />

3. Patrck Nwabueze Okechukwu, Boon Connie Gaberiel A. Akowuah,<br />

Anti-ulcer and Free radical scavenging effects of partial purified<br />

extract from the stem of Coscinium fenestratum International<br />

<strong>University</strong> Conference (WASET) 2011 August 24-26 Paris, France.<br />

4. Patrick Nwabueze Okechukwu Lee Jia Jai Gabriel Akyirem<br />

Akowuah, in-vitro antiasthmatic, antioxidant and mast cell stabilizing<br />

effects of crude dcm leaf extract of labisia pumila. , 25 rd MSPP<br />

Scientific meeting, May, Malaysia Oral (O027) 25-26th May 2011.<br />

5. Ikujuni Catherine Moyinoluwa,Kumutamalar Panrengam,Mariaini<br />

Rajagopal and Patrick Nwabueze Okechukwu (2010) ‘Studies on The<br />

<strong>UCSI</strong> <strong>University</strong><br />

Kuala Lumpur Campus<br />

No. 1 Jalan Menara Gading, <strong>UCSI</strong> Heights, 56000 Cheras, Kuala Lumpur, W. P. Kuala Lumpur.<br />

Tel: 03-91018880 Fax: 03-91023606 Website: www.ucsi.edu.my


Anti-inflammatary,Antinociceptive, and Antipyretics Activities of<br />

Extract from leaf’, labisia pumila 21 st Intervasity Biochemistry<br />

Seminar Oral (T14) 27 th March 2010.<br />

6. Wong, HC and Okechukwu, PN, ‘Isolation and Investigation of the<br />

hypotensive effect of semi – purified extract from the stem of<br />

Coscinium fenestratum’, paper presented at the 19 th Intervarsity<br />

Biochemistry Seminar <strong>University</strong> of Malaya, 22 nd March 2008.<br />

Peer Review Journal Publication:<br />

1. Okechukwu Patrick Nwabueze, Lee Jiajia Audrey and Akowuah<br />

Gabriel Akyirem. In vitro antihistaminergic and anticholinergic<br />

activities of dichloromethane crude leaf extract of labisia pumila<br />

International Journal of Pharmacology & Toxicology Science (In<br />

Press) 2011.<br />

2. Patrick Nwabueze Okechukwu, Ai Ching Connie Boon and<br />

Gabriel Akyirem Akowuah. Anti-ulcer and Free Radical<br />

Scavenging Effects of Partial Purified Fraction E from the Stem of<br />

Coscinium fenestratum. Journal of Life Science (In press) 2011.<br />

3. Okechukwu Nwabueze Patrick. The antihyperglycemic activity of<br />

partially purified extract from the roots of thottea grandiflora<br />

rottb. International Journal of Pharmacology & Toxicology<br />

Science 2011; 3: 22-31.<br />

4. Okechukwu PN and Loshnie Samuagam, The Study of<br />

Antinociceptive Effects of Meoh and Dcm Crude Extract from<br />

The Leaves of Labisia Pumila, Global Journal Pharmacology<br />

(GJP) 5 (3) : 181-185, 2011.<br />

5. Aman Ahmed Alzubier and Patrick Nwabueze Okechukwu,<br />

Investigation of Anti-inflammatory, Antipyretic and Analgesic<br />

Effect of Yemeni Sidr Honey WASET 80 (2011) 47-52.<br />

6. Okechukwu, NP, and Marunga,J, Gasteroprotective Effect of<br />

Dichloromethane Crude Extract of Labisia Pumila. International<br />

Journal of Pharmacology & Toxicology Science 2 (2011) 1-7<br />

7. Samuagam, L, Akowuah<br />

,GA, Okechukwu, PN, Partial<br />

<strong>UCSI</strong> <strong>University</strong><br />

Kuala Lumpur Campus<br />

No. 1 Jalan Menara Gading, <strong>UCSI</strong> Heights, 56000 Cheras, Kuala Lumpur, W. P. Kuala Lumpur.<br />

Tel: 03-91018880 Fax: 03-91023606 Website: www.ucsi.edu.my


Purification and Antinociceptive Investigation of Extracts of<br />

Leaves of labisia pumila . Asean Journal of Pharmacy and Clinical<br />

Research Vol 4 Issue 4 (2011) 44-46<br />

8. Selvaraja,M , Ndyeabura, AM, Akowuah,GA, Okechukwu, PN,<br />

Antidiabetic Activity of Crude Stem Extracts of Coscinium<br />

fenestratum on Streptozotocin-Induced Type-2 Diabetic Rats.<br />

Asean Journal of Pharmacy and Clinical Research Vol 4 Issue 4<br />

(2011) 47-51.<br />

<strong>UCSI</strong> <strong>University</strong><br />

Kuala Lumpur Campus<br />

No. 1 Jalan Menara Gading, <strong>UCSI</strong> Heights, 56000 Cheras, Kuala Lumpur, W. P. Kuala Lumpur.<br />

Tel: 03-91018880 Fax: 03-91023606 Website: www.ucsi.edu.my

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